Abstract: The invention provides, in one aspect, a compound represented by formula (I) or a stereoisomer, tautomer or pharmaceutical salt thereof, and use thereof in preparation of a medicament for preventing and/or treating estrogen receptor (ER)-related diseases or disorders.

Abstract: A control device with a touch screen and motion sensors is held in one hand with the screen facing the user. Preferably, thumb motion of the hand holding the control device on the touch screen sensor of the control device is the input to control the motion and animations of an avatar, wherein the avatar motion is displayed on the control device touch screen or, in an embodiment, on an external display device. An important aspect of the present invention is tilting the control device, causing an angular rotation velocity, which can trigger a game event such as throwing, kicking, shooting or other action of the game.

Abstract: A control device with a touch screen and motion sensors is held in one hand with the screen facing the user. Preferably, thumb motion of the hand holding the control device on the touch screen sensor of the control device is the input to control the motion and animations of an avatar, wherein the avatar motion is displayed on the control device touch screen or, in an embodiment, on an external display device. An important aspect of the present invention is tilting the control device, causing an angular rotation velocity, which can trigger a game event such as throwing, kicking, shooting or other action of the game.

Abstract: Inventive devices and methods for mounting a flat panel surface onto a flat receiving surface. The devices include a recessed extension spring (306) which results in the surfaces being joined without resulting in any appreciable gap between the panel and the flat receiving surface.

Abstract: Systems and methods for computing a distribution pattern of information whereby, as the rating of thought objects in a roundtable exchange proceeds, thought objects that are more highly rated and are therefore more likely to be chosen as subjects for discussion in groups, are more widely distributed to participant devices for rating, and for computing a pattern of assignment whereby each participant device is assigned to a group discussing a subject which that participant device rated highly, within constraints specified by the facilitator.

Abstract: Pressure vessels that operate at elevated temperatures and pressures (e.g., 600° F./316° C., 20000 psig), and ultrasonic transducers and signal connectors for use therein, are described. The pressure vessels include a housing defining a cavity. The housing includes a cylindrical body with plugs positioned within openings of the cylindrical body. Each plug has a recess extending from an external surface to a location ultrasonically adjacent the cavity. The pressure vessels additionally include transducer assemblies positioned within respective plug recesses. Each transducer assembly includes a signal connector positioned within the recess adjacent the external surface, a transducer having a piezoceramic element positioned within the recess at the location ultrasonically adjacent the cavity, and a metallic interconnection spring interconnecting the transducer to the signal connector.

Abstract: A method is provided. A center of mass of the bat is calculated based at least in part on the physical characteristics, the length, and the drop. A first and second mass distribution for an insert having a central axis and a length is calculated based at least in part on the calculated center of mass. The first mass distribution is symmetric about the central axis along the entire length, and the second mass distribution includes a first density for at least one low mass region and a second density for a high mass region with the second density is greater than the first density. Then, the insert is 3D printing based at least in part on the first and second mass distributions.

Abstract: A method is provided. A session is established with a server by a user, which included generating a symmetric session key, encrypting the symmetric session key with the server's public key to generate an encrypted session key, and transmitting the encrypted session key to the server. A user's physical characteristics are measured, and the user's physical characteristics are formatted into a transmission message. The transmission message is encrypted to generate an encrypted transmission message with the symmetric session key. The encrypted transmission message is transmitted to the server. A receive message is received from the server. The receive message is decrypted with the symmetric session key into a decrypted message, and the decrypted message is formatted into ordered bat data. The ordered bat data is then displayed.

Abstract: Pressure vessels that operate at elevated temperatures and pressures (e.g., 600° F./316° C., 20000 psig), and ultrasonic transducers and signal connectors for use therein, are described. The pressure vessels include a housing defining a cavity. The housing includes a cylindrical body with plugs positioned within openings of the cylindrical body. Each plug has a recess extending from an external surface to a location ultrasonically adjacent the cavity. The pressure vessels additionally include transducer assemblies positioned within respective plug recesses. Each transducer assembly includes a signal connector positioned within the recess adjacent the external surface, a transducer having a piezoceramic element positioned within the recess at the location ultrasonically adjacent the cavity, and a metallic interconnection spring interconnecting the transducer to the signal connector.

Abstract: Aspects of this disclosure generally are related to significant systems and methods of processing qualitative, comment-style, responses provided by a population, and for corresponding production of significant visualizations configured to efficiently facilitate insight into population characteristics and matters important to the population. According to some embodiments, qualitative, or open-ended, comment-style responses are assigned priority values by participants. Based at least on an analysis of these priority values, groups of participants, qualitative responses, or both, are identified, according to some embodiments. In some embodiments, a significant visualization is generated that visually presents the groups at least in part via clusters of visual representations of participants, qualitative responses, or both based at least on results of the analysis.

Abstract: A control device with a touch screen and motion sensors is held in one hand with the screen facing the user. Preferably, thumb motion of the hand holding the control device on the touch screen sensor of the control device is the input to control the motion and animations of an avatar, wherein the avatar motion is displayed on the control device touch screen or, in an embodiment, on an external display device. An important aspect of the present invention is tilting the control device, causing an angular rotation velocity, which can trigger a game event such as throwing, kicking, shooting or other action of the game.

Abstract: A method and system to analyze sports motions using the motion sensors of a mobile device, such as a smart phone, is provided. This method uses the mobile device motion sensor output to define the impact point with a virtual object, such as a golf ball, baseball or tennis ball. The motion sensor signature of the sports motion is analyzed for characteristics, specific to each type of sports motion. A method is disclosed using multiple sensors outputs in a mobile device to compute the impact point with a virtual object, such as a golf ball, baseball, tennis ball. Further, a method is disclosed where moving virtual sports objects interact with virtual sports motions and the responsive outputs are displayed on the mobile device and/or any Web-enabled display device.

Abstract: One aspect of the disclosure relates to a method of swinging a mobile device to simulate swinging of a golf club in order to evaluate a user's golf swing for customized golf club fitting. In an embodiment, the method can be performed by a processor of the mobile device. In another embodiment, the method can be performed for multiple mobile devices concurrently, the method performed at least in part on a cloud-based server. According to an aspect of the invention, a method comprises swinging a mobile device having motion sensors integrated therein to simulate a golf swing; evaluating the simulated golf swing to determine at least one characteristic of a custom-fitted golf club; and outputting information related to the determined at least one characteristic. In an embodiment, the mobile device is held by a user. In an alternate embodiment, the mobile device is attached to a golf club.

Abstract: A family of sports teaching applications that delivers customized lessons driven by the analysis of user body motions where data is captured via the accelerometer and gyroscope in a mobile device, such as a smartphone is provided. Each specific application is designed with motion data models that define proper form for athletes in club sports such as, but not limited to, golf, baseball hitting, hockey, polo, and racquet sports such as, but not limited to, table tennis, squash, badminton and throwing sports like baseball pitching, football, discus, javelin, and shot put, and other sports such as skiing and running. The Invention is also applicable to the customized fitting of sports equipment such as golf clubs, baseball bats, tennis racquets, etc. to athletes unique swing motions and swing speeds, and for multiplayer tournament competitions via the Internet utilizing the swing motion analysis and system described herein.

Abstract: Systems and methods are provided to connect a control device such as a mobile phone to a display device. The control device can be used to operate (control) an application executing at a server and/or at the display device. In an embodiment, the display device initiates a connection request to the server via a network. The server then generates a unique code, and transmits the code to the display device. The code can be displayed as a matrix barcode. The control device scans the matrix barcode and decodes it. The control device then initiates a connection request to the server and transmits the code to the server. A matching engine connects the control device to the display device corresponding to the code. The connections are preferably made via a full-duplex Internet connection protocol, such as the WebSocket protocol, to facilitate low latency network connections.

Abstract: A family of sports teaching applications that delivers customized lessons driven by the analysis of user body motions where data is captured via the accelerometer and gyroscope in a mobile device, such as a smartphone is provided. Each specific application is designed with motion data models that define proper form for athletes in club sports such as, but not limited to, golf, baseball hitting, hockey, polo, and racquet sports such as, but not limited to, table tennis, squash, badminton and throwing sports like baseball pitching, football, discus, javelin, and shot put, and other sports such as skiing and running. The Invention is also applicable to the customized fitting of sports equipment such as golf clubs, baseball bats, tennis racquets, etc. to athletes unique swing motions and swing speeds, and for multiplayer tournament competitions via the Internet utilizing the swing motion analysis and system described herein.

Abstract: One aspect of the disclosure relates to a method of swinging a mobile device to simulate swinging of a golf club in order to evaluate a user's golf swing for customized golf club fitting. In an embodiment, the method can be performed by a processor of the mobile device. In another embodiment, the method can be performed for multiple mobile devices concurrently, the method performed at least in part on a cloud-based server. According to an aspect of the invention, a method comprises swinging a mobile device having motion sensors integrated therein to simulate a golf swing; evaluating the simulated golf swing to determine at least one characteristic of a custom-fitted golf club; and outputting information related to the determined at least one characteristic. In an embodiment, the mobile device is held by a user. In an alternate embodiment, the mobile device is attached to a golf club.

Abstract: This invention is for control of a system using motion states of a control device. The method enables complex system control typically controlled by complex controllers, but does not require any buttons or actuators, or video capture of body movements or gesture. An embodiment of the invention utilizes the gyroscope and accelerometer motion sensors of a control device such as a smart phone, smart watch, fitness band, or other device with motion sensors connected, via a cable or wirelessly, to a processor for analysis and translation.

Abstract: A distributed gaming platform is provided wherein mobile devices (e.g., a smartphone) with motion sensors are used as input controllers of a game. A cloud-based gaming rules engine manages multiple players and the content for display in the game. The game output is displayed on any web-enabled display which is physically distinct from the mobile device. Multiple players may simultaneously play the same game, or different games, in multiple geographic locations.

Abstract: A method and system to analyze sports motions using the motion sensors of a mobile device, such as a smart phone, is provided. This method uses the mobile device motion sensor output to define the impact point with a virtual object, such as a golf ball, baseball or tennis ball. The motion sensor signature of the sports motion is analyzed for characteristics, specific to each type of sports motion. A method is disclosed using multiple sensors outputs in a mobile device to compute the impact point with a virtual object, such as a golf ball, baseball, tennis ball. Further, a method is disclosed where moving virtual sports objects interact with virtual sports motions and the responsive outputs are displayed on the mobile device and/or any Web-enabled display device.