Abstract: A class of pyrazole derivatives is described for use in treating p38 kinase mediated disorders. Compounds of particular interest are defined by Formula IA wherein R1, R2, R3 and R4 are as described in the specification.

Abstract: An array of micromachined mirrors are arranged on a first substrate at the intersections of input and output optical paths and oriented at approximately forty-five degrees to the paths. An array of split-electrodes are arranged on a second substrate above the respective mirrors. Each split electrode includes a first electrode configured to apply an electrostatic force that rotates the mirror approximately ninety degrees into one of the input optical paths to deflect the optical signal along one of the output optical paths, and a second electrode configured to apply an electrostatic force that maintains the mirror position. Stability may be improved by using the first and second electrodes in combination to first actuate the mirror and then balance the forces on the mirror to maintain its position. Reproducibly accurate positioning of the mirrors requires either the use of active positioning control or of mechanical stops.

Abstract: The inside out gas turbine cleaning method is a new method to clean axial gas turbine compressors. This is done by inserting a specially and fabricated flexible hose with nozzles on it into the first several stages of an off line gas turbine compressor. High pressure hot water with detergent is supplied to the hose and as it is withdrawn from the compressor it blasts dirt from the airfoil surfaces in the compressor. Conventional cleaning sprays water in one direction down the throat of the gas turbine compressor, whereas this method cleans from the back forward giving a different blast angle with higher pressure water (see FIG. 1). Using both the conventional cleaning method and this new process, the compressor can be cleaned better allowing for improved gas turbine power and fuel efficiency.

Abstract: A multi-track density direct access storage device is disclosed. In accordance with a preferred embodiment of the present invention, a direct access storage device for data storage within a data processing system comprises a housing, a rotatable spindle, at least one disk, and several heads. The disk is fixedly mounted to the rotatable spindle, and the rotatable spindle is rotated by a motor within the housing. A first disk surface of the disk has a first track density and a second disk surface of the disk has a second track density; wherein the second track density is preferably greater than the first track density. Each of the several heads contains a transducer to read and write information from and to the disk during the disk rotation.

Abstract: Apparatus and methods are provided for selecting farms to grow a crop of interest and/or for performing economic analysis relating to growing a crop of interest. One such disclosed apparatus includes a database and a farm identifier in communication with the database to develop a set of farms capable of growing the crop of interest. The apparatus also includes a competition analyzer cooperating with the farm identifier to estimate profits to be earned by farms in the set of farms for growing at least one crop which is different from the crop of interest. The apparatus is further provided with an offer developer cooperating with the competition analyzer to determine possible offers to be made to the farms in the set of farms based at least in part upon the estimated profits to be earned for growing the at least one crop which is different from the crop of interest.

Abstract: The present invention provides resin compositions comprising a thermoplastic resin and at least one phosphoramide having a glass transition point of at least about 0° C., preferably of at least about 10° C., and most preferably of at least about 20° C. The present invention also relates to articles made from the resin compositions. The present invention also provides methods to make the resin compositions-having improved heat properties over compositions known in the art.

Abstract: In a ultra high density, multiple-disk drive, track switches within a cylinder of tracks as well as track switches to tracks on other cylinders both require a movement of the head stack actuator. Track switching latency in such a disk drive is reduced by overlapping pre-movement portions of the track switching process with the data transfer operation of the currently active recording head. In addition, post-movement portions of the track switching process are overlapped with the movement of the heads so that the next selected read/write head may begin a data transfer operation immediately upon arrival at the next track. Further, the pre-movement and post-movement portions of the track-switch process may be overlapped with low displacement movement of the read/write heads relative to the currently active track or the next track.

Abstract: An infusible-grade storage medium that is capable of preserving the viability and function of stem cells, nucleated cells and other hematopoietic cells is provided.

Abstract: A method of characterizing a test sample of genomic DNA which method comprises contacting the test sample with type specific primer to prime selectively, within a telomere repeat array, internal repeat units of that type, and extending the type specific primers in the presence of appropriate nucleoside triphosphates and an agent for polymerization thereof to produce a set of amplification products extending from the internal repeat units of that type to at least the end of the telomere repeat array.

Abstract: The present invention provides resin compositions comprising a thermoplastic resin and at least one phosphoramide having a glass transition point of at least about 0° C., preferably of at least about 10° C., and most preferably of at least about 20° C., of the formula: wherein Q1 is oxygen or sulfur; R1 is an amine residue, and R2 and R3 are each independently an alkyloxy, alkylthio, aryloxy, or arylthio residue, or an aryloxy or arylthio residue containing at least one alkyl substitution; or an amine residue. The present invention also relates to articles made from the resin compositions. The present invention also provides methods to make the resin compositions having improved heat properties over compositions known in the art.

Abstract: An artificial knee comprises first and second pivotally interconnected knee components and first and second interengaging brake components for locking the knee components together. The first and second brake components are associated respectively with the first and second knee components, respectively. The second brake component is made of a resiliently deformable material. The arrangement is such that, when the artificial knee is subjected to a first load condition, the brake components are substantially free to slide against one another, and when the artificial knee is under a second, higher load condition, the second brake component is resiliently deformed against the first brake component to lock the two brake components together, thereby locking the two knee components together.

Abstract: An artificial limb has an endoskeletal shin component which is of generally constant H-shaped cross section and is formed by injection molding from thermoplastics material. In a preferred embodiment, the limb has a foot keel which is integrally molded with the shin component. The keel also has upper flanges which are contiguous with anterior and posterior flanges of the shin component. Such a limb can be made light in weight yet strong in terms of resistance to transverse bending moments, and can be inexpensively produced. The constant cross section of the shin component allows it to be cut to a required length and clamped to an upper limb component.

Abstract: A method and apparatus are provided for variable spindle rotation speed in a direct access storage device (DASD). The direct access storage device (DASD) includes a multi-phase, brushless, direct current (DC) spindle motor. Speed and commutation control signals are applied to a plurality of spindle motor drivers for normally operating the plurality of spindle motor drivers in saturation mode while performing read and write operations. A spindle rotational speed is detected and compared with a predetermined spindle speed range. Responsive to the detected spindle rotational speed being within said predetermined spindle speed range, normal operations of the direct access storage device (DASD) are enabled. One or more write sync fields are provided on each surface of a magnetic disk media. The write sync field is used for timing write operations in the direct access storage device.

Abstract: A ball tossing or teeing device (20) includes a housing (21) which carries an operating mechanism (22). A pedal (30) is depressible to actuate the operating mechanism (22) such that upon a single depression and release of pedal (30), the operating mechanism (22) launches a ball and positions another ball in place for launching. A chute (24) can be attached to the housing (21) and carries a tee (25). When the chute (24) is attached to the housing (21), the ball will move up the chute (24) and be placed on the tee (25) upon activation of the operating mechanism (22).

Abstract: A unitary foot and shin component for a lower limb prosthesis has a one piece thermoplastic endoskeletal foot keel and shin member and a continuous flexible cosmesis. The cosmesis includes a resilient foot body which is molded directly onto the keel so as to embed the keel, and an integral flexible and hollow shell which surrounds the shin member but is spaced from it. By forming the foot body and the hollow shell as a single polyurethane molding, the foot and shin can be supplied as a single component, ready for connection to a stump socket and alignment coupling.

Abstract: A multi-track density direct access storage device is disclosed. In accordance with a preferred embodiment of the present invention, a direct access storage device for data storage within a data processing system comprises a housing, a rotatable spindle, at least one disk, and several heads. The disk is fixedly mounted to the rotatable spindle, and the rotatable spindle is rotated by a motor within the housing. A first disk surface of the disk has a first track density and a second disk surface of the disk has a second track density; wherein the second track density is preferably greater than the first track density. Each of the several heads contains a transducer to read and write information from and to the disk during the disk rotation.

Abstract: Bisphosphoramidates such as N,N'-bis[di-(2,6-xylenoxy)phosphinyl]piperazine are effective flame retardant agents for thermoplastic polymers and blends thereof. In addition, the blends containing such bisphosphoramidates have excellent high temperature properties, as demonstrated by high heat deflection temperatures and a low tendency to decrease glass transition temperature.

Abstract: An infusible-grade storage medium that is capable of preserving the viability and function of stem cells, nucleated cells and other hematopoietic cells is provided.

Abstract: A system for fastening aircraft assemblies is disclosed. The system comprises a first wing clip (10) having an anchor plate (12) with at least one ear (20) for affixing to a first assembly (16); a second wing clip (11) having an anchor plate (14) and at least one ear (20) for affixing to a second assembly (18); and a fastener (44) for joining the first wing clip (10) to the second wing clip (11).