Patents by Inventor John K. Fink

John K. Fink has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for detecting and treating neurological conditions
    Patent number: 9868990
    Abstract: The present invention relates to the NIPA-1 proteins and nucleic acids encoding the NIPA-1 proteins. The present invention further provides assays for the detection of NIPA-1 polymorphisms and mutations associated with disease states, as well as methods of screening for ligands and modulators of NIPA-1 proteins.
    Type: Grant
    Filed: February 3, 2016
    Date of Patent: January 16, 2018
    Assignees: The Regents of the University of Michigan, The Trustees of the University of Pennsylvania
    Inventors: John K. Fink, Shirley Rainier, Robert D. Nicholls, Jinghua Chai
  • Compositions for diagnosing episodic movement disorders and related conditions
    Patent number: 9758832
    Abstract: The present invention provides compositions and methods for research, diagnostic, drug screening, and therapeutic applications related to paroxysmal dystonic choreoathetosis and related conditions. In particular, the present invention provides mutations in the myofibrillogenesis regulator 1 (MR-1) gene associated with such conditions.
    Type: Grant
    Filed: July 15, 2016
    Date of Patent: September 12, 2017
    Assignee: The Regents of the University of Michigan
    Inventors: John K. Fink, Shirley Rainier
  • METHODS FOR DIAGNOSING EPISODIC MOVEMENT DISORDERS AND RELATED CONDITIONS
    Publication number: 20160319359
    Abstract: The present invention provides compositions and methods for research, diagnostic, drug screening, and therapeutic applications related to paroxysmal dystonic choreoathetosis and related conditions. In particular, the present invention provides mutations in the myofibrillogenesis regulator 1 (MR-1) gene associated with such conditions.
    Type: Application
    Filed: July 15, 2016
    Publication date: November 3, 2016
    Inventors: John K. Fink, Shirley Rainier
  • Methods for diagnosing episodic movement disorders and related conditions
    Patent number: 9416421
    Abstract: The present invention provides compositions and methods for research, diagnostic, drug screening, and therapeutic applications related to paroxysmal dystonic choreoathetosis and related conditions. In particular, the present invention provides mutations in the myofibrillogenesis regulator 1 (MR-1) gene associated with such conditions.
    Type: Grant
    Filed: July 3, 2013
    Date of Patent: August 16, 2016
    Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: John K. Fink, Shirley Rainier
  • COMPOSITIONS AND METHODS FOR DETECTING AND TREATING NEUROLOGICAL CONDITIONS
    Publication number: 20160230228
    Abstract: The present invention relates to the NIPA-1 proteins and nucleic acids encoding the NIPA-1 proteins. The present invention further provides assays for the detection of NIPA-1 polymorphisms and mutations associated with disease states, as well as methods of screening for ligands and modulators of NIPA-1 proteins.
    Type: Application
    Filed: February 3, 2016
    Publication date: August 11, 2016
    Inventors: John K. Fink, Shirley Rainier, Robert D. Nicholls, Jinghua Chai
  • Compositions and methods for detecting and treating neurological conditions
    Patent number: 9285375
    Abstract: The present invention relates to the NIPA-1 proteins and nucleic acids encoding the NIPA-1 proteins. The present invention further provides assays for the detection of NIPA-1 polymorphisms and mutations associated with disease states, as well as methods of screening for ligands and modulators of NIPA-1 proteins.
    Type: Grant
    Filed: August 8, 2013
    Date of Patent: March 15, 2016
    Assignees: The Regents of the University of Michigan, The Trustees of the University of Pennsylvania
    Inventors: John K. Fink, Shirley Rainier, Robert D. Nicholls, Jinghua Chai
  • COMPOSITIONS AND METHODS FOR DETECTING AND TREATING NEUROLOGICAL CONDITIONS
    Publication number: 20130326646
    Abstract: The present invention relates to the NIPA-1 proteins and nucleic acids encoding the NIPA-1 proteins. The present invention further provides assays for the detection of NIPA-1 polymorphisms and mutations associated with disease states, as well as methods of screening for ligands and modulators of NIPA-1 proteins.
    Type: Application
    Filed: August 8, 2013
    Publication date: December 5, 2013
    Applicants: The Trustees of the University of Pennsylvania, The Regents of the University of Michigan
    Inventors: John K. Fink, Shirley Rainer, Robert D. Nicholls, Jinghua Chai
  • METHODS FOR DIAGNOSING EPISODIC MOVEMENT DISORDERS AND RELATED CONDITIONS
    Publication number: 20130302802
    Abstract: The present invention provides compositions and methods for research, diagnostic, drug screening, and therapeutic applications related to paroxysmal dystonic choreoathetosis and related conditions. In particular, the present invention provides mutations in the myofibrillogenesis regulator 1 (MR-1) gene associated with such conditions.
    Type: Application
    Filed: July 3, 2013
    Publication date: November 14, 2013
    Inventors: John K. Fink, Shirley Rainier
  • Compositions and methods for detecting and treating neurological conditions
    Patent number: 8518638
    Abstract: The present invention relates to the NIPA-1 proteins and nucleic acids encoding the NIPA-1 proteins. The present invention further provides assays for the detection of NIPA-1 polymorphisms and mutations associated with disease states, as well as methods of screening for ligands and modulators of NIPA-1 proteins.
    Type: Grant
    Filed: February 7, 2008
    Date of Patent: August 27, 2013
    Assignee: The Regents of the University of Michigan
    Inventors: John K. Fink, Shirley Rainier, Robert D. Nicholls, Jinghua Chai
  • Methods for diagnosing episodic movement disorders and related conditions
    Patent number: 8481260
    Abstract: The present invention provides compositions and methods for research, diagnostic, drug screening, and therapeutic applications related to paroxysmal dystonic choreoathetosis and related conditions. In particular, the present invention provides mutations in the myofibrillogenesis regulator 1 (MR-1) gene associated with such conditions.
    Type: Grant
    Filed: March 23, 2010
    Date of Patent: July 9, 2013
    Assignee: The Regents of the University of Michigan
    Inventors: John K. Fink, Shirley Rainier
  • METHODS FOR DIAGNOSING EPISODIC MOVEMENT DISORDERS AND RELATED CONDITIONS
    Publication number: 20100227330
    Abstract: The present invention provides compositions and methods for research, diagnostic, drug screening, and therapeutic applications related to paroxysmal dystonic choreoathetosis and related conditions. In particular, the present invention provides mutations in the myofibrillogenesis regulator 1 (MR-1) gene associated with such conditions.
    Type: Application
    Filed: March 23, 2010
    Publication date: September 9, 2010
    Applicant: The Regents of the University of Michigan
    Inventors: John K. Fink, Shirley Rainier
  • Methods for diagnosing episodic movement disorders and related conditions
    Patent number: 7727719
    Abstract: The present invention provides compositions and methods for research, diagnostic, drug screening, and therapeutic applications related to paroxysmal dystonic choreoathetosis and related conditions. In particular, the present invention provides mutations in the myofibrillogenesis regulator 1 (MR-1) gene associated with such conditions.
    Type: Grant
    Filed: June 27, 2005
    Date of Patent: June 1, 2010
    Assignee: The Regents of the University of Michigan
    Inventors: John K. Fink, Shirley Rainier
  • Atlastin
    Patent number: 7649088
    Abstract: The present invention relates to methods and compositions of a novel gene and the peptide encoded by the gene. Mutations in the gene, named atlastin, are factors in the disease Hereditary Spastic Paraplegia and related disorders. The present invention will be used for the in the research, diagnosis and treatment of these disabling diseases.
    Type: Grant
    Filed: September 19, 2006
    Date of Patent: January 19, 2010
    Assignee: The Regents of the University of Michigan
    Inventors: John K. Fink, Xinping Zhao
  • Atlastin
    Patent number: 7582425
    Abstract: The present invention relates to methods and compositions of a novel gene and the peptide encoded by the gene. Mutations in the gene, named atlastin, are factors in the disease Hereditary Spastic Paraplegia and related disorders. The present invention will be used for the in the research, diagnosis and treatment of these disabling diseases.
    Type: Grant
    Filed: February 11, 2003
    Date of Patent: September 1, 2009
    Assignee: The Regents of the University of Michigan
    Inventors: John K. Fink, Xinping Zhao
  • ATLASTIN
    Publication number: 20090215065
    Abstract: The present invention relates to methods and compositions of a novel gene and the peptide encoded by the gene. Mutations in the gene, named atlastin, are factors in the disease Hereditary Spastic Paraplegia and related disorders. The present invention will be used for the in the research, diagnosis and treatment of these disabling diseases.
    Type: Application
    Filed: March 27, 2009
    Publication date: August 27, 2009
    Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: John K. Fink, Xinping Zhao
  • Compositions And Methods For Detecting And Treating Neurological Conditions
    Publication number: 20080249053
    Abstract: The present invention relates to the NIPA-1 proteins and nucleic acids encoding the NIPA-1 proteins. The present invention further provides assays for the detection of NIPA-1 polymorphisms and mutations associated with disease states, as well as methods of screening for ligands and modulators of NIPA-1 proteins.
    Type: Application
    Filed: February 7, 2008
    Publication date: October 9, 2008
    Applicants: The Regents of the University of Michigan, The Trustees of the University of Pennsylvania
    Inventors: John K. Fink, Shirley Rainer, Robert D. Nicholls, Jinghua Chai
  • Compositions and methods for detecting and treating motor neuron disorders
    Patent number: 7384748
    Abstract: The present invention relates to the NTE proteins and nucleic acids encoding the NTE proteins. The present invention further provides assays for the detection of NTE polymorphisms and mutations associated with disease states, as well as methods of screening for ligands and modulators of NTE proteins.
    Type: Grant
    Filed: December 13, 2005
    Date of Patent: June 10, 2008
    Assignee: The Regents of the University of Michigan
    Inventors: John K. Fink, Shirley Rainer
  • Compositions and methods for detecting and treating neurological conditions
    Patent number: 7332282
    Abstract: The present invention relates to the NIPA-1 proteins and nucleic acids encoding the NIPA-1 proteins. The present invention further provides assays for the detection of NIPA-1 polymorphisms and mutations associated with disease states, as well as methods of screening for ligands and modulators of NIPA-1 proteins.
    Type: Grant
    Filed: August 19, 2004
    Date of Patent: February 19, 2008
    Assignee: The Regents of the University of Michigan
    Inventors: John K. Fink, Shirley Rainier, Robert D. Nicholls, Jinghua Chai
  • Atlastin
    Patent number: 7108975
    Abstract: The present invention relates to methods and compositions of a novel gene and the peptide encoded by the gene. Mutations in the gene, named atlastin, are factors in the disease Hereditary Spastic Paraplegia and related disorders. The present invention will be used for the in the research, diagnosis and treatment of these disabling diseases.
    Type: Grant
    Filed: September 12, 2002
    Date of Patent: September 19, 2006
    Assignee: Regents of the University of Michigan
    Inventors: John K. Fink, Xinping Zhao
  • Atlastin
    Publication number: 20030224968
    Abstract: The present invention relates to methods and compositions of a novel gene and the peptide encoded by the gene. Mutations in the gene, named atlastin, are factors in the disease Hereditary Spastic Paraplegia and related disorders. The present invention will be used for the in the research, diagnosis and treatment of these disabling diseases.
    Type: Application
    Filed: February 11, 2003
    Publication date: December 4, 2003
    Applicant: The Regents Of The University Of Michigan
    Inventors: John K. Fink, Xinping Zhao