Patents by Inventor John K. Fraser

John K. Fraser has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20160310540
    Abstract: Cells present in adipose tissue are used to promote wound healing in a patient. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of regenerative cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the regenerative cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, cells present in adipose tissue are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic benefit.
    Type: Application
    Filed: July 6, 2016
    Publication date: October 27, 2016
    Inventors: John K. Fraser, Marc H. Hedrick, Eric Daniels
  • Patent number: 9463203
    Abstract: Regenerative cells present in adipose tissue are used to treat patients, including patients with musculoskeletal diseases or disorders. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of regenerative cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, regenerative cells present in adipose tissue are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic musculoskeletal benefit.
    Type: Grant
    Filed: August 18, 2014
    Date of Patent: October 11, 2016
    Assignee: Cytori Therapeutics, Inc.
    Inventors: Marc H. Hedrick, John K. Fraser, Susan L. Riley, Ronda E. Schreiber
  • Publication number: 20160143952
    Abstract: Cells present in processed lipoaspirate tissue are used to treat patients. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Compositions that are administered to a patient include a mixture of adipose tissue and stem cells so that the composition has a higher concentration of stem cells than when the adipose tissue was removed from the patient.
    Type: Application
    Filed: November 30, 2015
    Publication date: May 26, 2016
    Inventors: John K. Fraser, Marc H. Hedrick
  • Publication number: 20160137970
    Abstract: Systems and methods are described that are used to separate cells from a wide variety of tissues. In particular, automated systems and methods are described that separate regenerative cells, e.g., stem and/or progenitor cells, from adipose tissue. The systems and methods described herein provide rapid and reliable methods of separating and concentrating regenerative cells suitable for re-infusion into a subject.
    Type: Application
    Filed: October 12, 2015
    Publication date: May 19, 2016
    Inventors: Marc H. Hedrick, John K. Fraser, Michael J. Schulzki, Bobby Byrnes, Grace Carlson, Ronda Elizabeth Schreiber, Isabella Wulur
  • Publication number: 20160113967
    Abstract: The invention provides methods for manipulating regenerative cells from adipose tissue. Specifically, it provides methods for enrichment of desired cells and enhancement of their therapeutic effects.
    Type: Application
    Filed: September 21, 2015
    Publication date: April 28, 2016
    Inventors: Marc H. Hedrick, John K. Fraser
  • Patent number: 9198937
    Abstract: Cells present in processed lipoaspirate tissue are used to treat patients. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Compositions that are administered to a patient include a mixture of adipose tissue and stem cells so that the composition has a higher concentration of stem cells than when the adipose tissue was removed from the patient.
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: December 1, 2015
    Assignee: Cytori Therapeutics, Inc.
    Inventors: John K. Fraser, Marc H. Hedrick
  • Publication number: 20150196601
    Abstract: Cells present in adipose tissue are used to treat patients, including patients with PVD and related diseases or disorders. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, cells present in adipose tissue are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic benefit.
    Type: Application
    Filed: December 11, 2014
    Publication date: July 16, 2015
    Inventors: John K. Fraser, Marc H. Hedrick, Eric Daniels
  • Publication number: 20150152375
    Abstract: Systems and methods are described that are used to separate cells from a wide variety of tissues. In particular, automated systems and methods are described that separate regenerative cells, e.g., stem and/or progenitor cells, from adipose tissue. The systems and methods described herein provide rapid and reliable methods of separating and concentrating regenerative cells suitable for re-infusion into a subject.
    Type: Application
    Filed: November 10, 2014
    Publication date: June 4, 2015
    Inventors: Marc H. Hedrick, John K. Fraser, Michael J. Schulzki, Bobby Byrnes, Grace Carlson, Ronda Elizabeth Schreiber, Isabella Wulur
  • Publication number: 20150023931
    Abstract: Regenerative cells present in adipose tissue are used to treat patients, including patients with musculoskeletal diseases or disorders. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of regenerative cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, regenerative cells present in adipose tissue are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic musculoskeletal benefit.
    Type: Application
    Filed: August 18, 2014
    Publication date: January 22, 2015
    Inventors: Marc H. Hedrick, John K. Fraser, Susan L. Riley, Ronda E. Schreiber
  • Publication number: 20140369970
    Abstract: Aspects of the invention provides methods for preparing and using adipose-tissue-derived stem and progenitor cells, adipose-tissue-derived lymphatic endothelial cells, and cells capable of differentiating into lymphatic endothelial cells to treat disorders of the lymphatic system and to modulate expansion, repair, and/or regeneration of the lymphatic system. The invention further provides using adipose-tissue-derived lymphatic endothelial cells and cells capable of differentiating into lymphatic endothelial cells for delivery of therapeutic agents to tumor cells as a means for treating malignant disease, and assays to screen for drugs that modulate lymphatic system expansion, repair or regeneration.
    Type: Application
    Filed: July 21, 2014
    Publication date: December 18, 2014
    Inventors: Zeni Alfonso, John K. Fraser
  • Patent number: 8883499
    Abstract: Systems and methods are described that are used to separate cells from a wide variety of tissues. In particular, automated systems and methods are described that separate regenerative cells, e.g., stem and/or progenitor cells, from adipose tissue. The systems and methods described herein provide rapid and reliable methods of separating and concentrating regenerative cells suitable for re-infusion into a subject.
    Type: Grant
    Filed: April 20, 2012
    Date of Patent: November 11, 2014
    Assignee: Cytori Therapeutics, Inc.
    Inventors: Marc H. Hedrick, John K. Fraser, Michael J. Schulzki, Bobby Byrnes, Grace Carlson, Ronda Elizabeth Schreiber, Isabella Wulur
  • Publication number: 20140227341
    Abstract: Cells present in adipose tissue are used to promote wound healing in a patient. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of regenerative cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the regenerative cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, cells present in adipose tissue are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic benefit.
    Type: Application
    Filed: February 14, 2014
    Publication date: August 14, 2014
    Applicant: CYTORI THERAPEUTICS, INC.
    Inventors: John K. Fraser, Marc H. Hedrick, Eric Daniels
  • Publication number: 20140227234
    Abstract: Cells present in adipose tissue are used to promote wound healing in a patient. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of regenerative cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the regenerative cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, cells present in adipose tissue are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic benefit.
    Type: Application
    Filed: February 14, 2014
    Publication date: August 14, 2014
    Applicant: CYTORI THERAPEUTICS, INC.
    Inventors: John K. Fraser, Marc H. Hedrick, Eric Daniels
  • Patent number: 8784801
    Abstract: Aspects of the invention provides methods for preparing and using adipose-tissue-derived stem and progenitor cells, adipose-tissue-derived lymphatic endothelial cells, and cells capable of differentiating into lymphatic endothelial cells to treat disorders of the lymphatic system and to modulate expansion, repair, and/or regeneration of the lymphatic system. The invention further provides using adipose-tissue-derived lymphatic endothelial cells and cells capable of differentiating into lymphatic endothelial cells for delivery of therapeutic agents to tumor cells as a means for treating malignant disease, and assays to screen for drugs that modulate lymphatic system expansion, repair or regeneration.
    Type: Grant
    Filed: February 18, 2011
    Date of Patent: July 22, 2014
    Assignee: Cytori Therapeutics, Inc.
    Inventors: Zeni Alfonso, John K. Fraser
  • Patent number: 8771678
    Abstract: Methods of treating patients for conditions such as breast augmentation, soft tissue defects, and urinary incontinence, are described. The methods include removing adipose tissue from a patient, processing a portion of the adipose tissue to obtain a substantially isolated population of cells comprising disaggregated adipose-derived stem cells, mixing the concentrated population of adipose-derived cells comprising disaggregated adipose-derived cells with a portion of unprocessed, intact, non-disaggregated adipose tissue to form a composition, and administering the composition to the patient from which the adipose tissue was removed.
    Type: Grant
    Filed: August 17, 2012
    Date of Patent: July 8, 2014
    Assignee: Cytori Therapeutics, Inc.
    Inventors: Marc H. Hedrick, John K. Fraser
  • Patent number: 8691216
    Abstract: Cells present in adipose tissue are used to promote wound healing in a patient. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of regenerative cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the regenerative cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, cells present in adipose tissue are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic benefit.
    Type: Grant
    Filed: January 27, 2012
    Date of Patent: April 8, 2014
    Assignee: Cytori Therapeutics, Inc.
    Inventors: John K. Fraser, Marc H. Hedrick, Eric Daniels
  • Publication number: 20130344035
    Abstract: Cells present in processed lipoaspirate tissue are used to treat patients, including patients with renal conditions, diseases or disorders. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, cells present in processed lipoaspirate are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic renal benefit.
    Type: Application
    Filed: March 25, 2013
    Publication date: December 26, 2013
    Inventors: JOHN K. FRASER, MARC H. HEDRICK, ERIC DANIELS
  • Publication number: 20130288290
    Abstract: The invention provides methods for manipulating regenerative cells from adipose tissue. Specifically, it provides methods for enrichment of desired cells and enhancement of their therapeutic effects.
    Type: Application
    Filed: June 25, 2013
    Publication date: October 31, 2013
    Inventors: Marc H. Hedrick, John K. Fraser
  • Patent number: 8404229
    Abstract: Cells present in processed lipoaspirate tissue are used to treat patients, including patients with renal conditions, diseases or disorders. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, cells present in processed lipoaspirate are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic renal benefit.
    Type: Grant
    Filed: July 1, 2004
    Date of Patent: March 26, 2013
    Assignee: Cytori Therapeutics, Inc.
    Inventors: John K. Fraser, Marc H. Hedrick, Eric Daniels
  • Publication number: 20130060338
    Abstract: The present invention relates to a device comprising a cell carrier portion containing regenerative cells, e.g., stem and progenitor cells, and a cell carrier containment portion. The device is useful for the treatment of bone related disorders, including spinal fusion related disorders and long bone or flat bone related defects. The device may be used in conjunction with disclosed automated systems and methods for separating and concentrating regenerative cells.
    Type: Application
    Filed: August 29, 2012
    Publication date: March 7, 2013
    Applicant: CYTORI THERAPEUTICS, INC.
    Inventors: Marc H. Hedrick, John K. Fraser, Susan Lynn Riley, Joseph W. Tai