Patents by Inventor John K. Hoffman

John K. Hoffman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10285693
    Abstract: A surgical instrument and method of manipulating tissue of a patient includes a body, a shaft assembly extending distally therefrom, and an end effector extending distally from the shaft assembly and configured to receive a cartridge for manipulating tissue. The end effector has a distal end portion, a proximal end portion, a gap between the distal and proximal end portions, and a retaining pin. The retaining pin includes a distal head and is selectively movable from an open position to a locked closed position. In the open position, the retaining pin is proximally positioned such that the gap is configured to receive tissue. In the locked closed position, the retaining pin extends across the gap and is configured to capture tissue within the gap. The distal head of the retaining pin is configured engage and secure the distal end portion relative to the proximal end portion via the retaining pin.
    Type: Grant
    Filed: December 31, 2015
    Date of Patent: May 14, 2019
    Assignee: Ethicon LLC
    Inventors: John S. Kimsey, Anil K. Nalagatla, Hector Chow, Sudhir Patel, Douglas B. Hoffman, Thomas Adams
  • Patent number: 10076441
    Abstract: A method for cerebral cooling is described using a cooling assembly, which includes first and second elongate tubular members adapted for insertion into a nasal cavity of a patient through the patient's nostrils. The elongate tubular members each have a proximal end, a distal end, a lumen extending therebetween, and a plurality of ports in fluid communication with the lumen. The cooling assembly also includes a manifold and a reservoir, which contains a pressurized fluid that includes a propellant having a boiling point less than 22° C. The elongate tubular members are inserted into the nasal cavity through the patient's nostrils and pressurized fluid is delivered onto a surface of the nasal cavity by infusing the pressurized fluid from the reservoir through the manifold, into the lumens and through the plurality of ports of the first and second elongate tubular members.
    Type: Grant
    Filed: June 6, 2016
    Date of Patent: September 18, 2018
    Assignee: BrainCool AB
    Inventors: Allan Rozenberg, John K Hoffman, James D Savage
  • Patent number: 9775741
    Abstract: Methods for cerebral cooling are described. Cooling assemblies include elongate tubular members, a reservoir containing a pressurized fluid, and a manifold connecting the reservoir and elongate tubular members. After insertion of the elongate tubular members into the patient's nostrils, a pressurized fluid is delivered onto a surface of the patient's nasal cavity through a plurality of ports in the elongate tubular members. The delivery of the fluid causes cooling by direct heat transfer through the nasopharynx and hematogenous cooling through the carotids and the Circle of Willis.
    Type: Grant
    Filed: April 30, 2014
    Date of Patent: October 3, 2017
    Assignee: BrainCool AB
    Inventors: Denise Barbut, Alan Rozenberg, John K Hoffman, Thomas H Shaffer
  • Publication number: 20170027746
    Abstract: A method for cerebral cooling is described using a cooling assembly, which includes first and second elongate tubular members adapted for insertion into a nasal cavity of a patient through the patient's nostrils. The elongate tubular members each have a proximal end, a distal end, a lumen extending therebetween, and a plurality of ports in fluid communication with the lumen. The cooling assembly also includes a manifold and a reservoir, which contains a pressurized fluid that includes a propellant having a boiling point less than 22° C. The elongate tubular members are inserted into the nasal cavity through the patient's nostrils and pressurized fluid is delivered onto a surface of the nasal cavity by infusing the pressurized fluid from the reservoir through the manifold, into the lumens and through the plurality of ports of the first and second elongate tubular members.
    Type: Application
    Filed: June 6, 2016
    Publication date: February 2, 2017
    Applicant: BrainCool AB
    Inventors: ALLAN ROZENBERG, JOHN K HOFFMAN, JAMES D SAVAGE
  • Publication number: 20170027745
    Abstract: Devices for cerebral and systemic cooling via a patient's nasopharyngeal cavity are described. Cooling assemblies include at least one elongate tubular member having first and second lumens, a source of liquid coolant, a gas source communicating with the first lumen, and a switch for alternately connecting the liquid coolant source to the second lumen. The first lumen transports a compressed gas and the second lumen transports a volatile liquid. The pressurized fluid may be a perflurocarbon. The perfluorocarbon may be perfluorohexane, perfluoropentane, or 2-methyl-perfluoropentane. The gas may be air, oxygen, or a combination.
    Type: Application
    Filed: June 2, 2016
    Publication date: February 2, 2017
    Inventors: Allan ROZENBERG, Denise BARBUT, John K. HOFFMAN, Thomas H. SHAFFER
  • Patent number: 9358150
    Abstract: Methods for cerebral and systemic cooling via a patient's nasopharyngeal cavity are described. In one method, a cooling assembly is inserted into a nasal cavity through a patient's nostril. A substantially dry gas is delivered through a lumen of the catheter onto the surface of the patient's nasal cavity. Evaporative heat loss cools the patient's nasal cavity. If additional cooling is needed, a liquid coolant is delivered through a separated lumen of the catheter. The liquid coolant is nebulized at a plurality of delivery ports on the distal end of the catheter and is delivered onto the surface of the patient's nasal cavity in combination with the dry gas. The dry gas enhances evaporation of the nebulized coolant and additional cooling is provided from the evaporative heat loss of the liquid coolant.
    Type: Grant
    Filed: March 19, 2012
    Date of Patent: June 7, 2016
    Assignee: BeneChill, Inc.
    Inventors: Allan Rozenberg, Denise Barbut, John K Hoffman, Thomas H Shaffer
  • Publication number: 20140343641
    Abstract: Methods for cerebral cooling are described. Cooling assemblies include elongate tubular members, a reservoir containing a pressurized fluid, and a manifold connecting the reservoir and elongate tubular members. After insertion of the elongate tubular members into the patient's nostrils, a pressurized fluid is delivered onto a surface of the patient's nasal cavity through a plurality of ports in the elongate tubular members. The delivery of the fluid causes cooling by direct heat transfer through the nasopharynx and hematogenous cooling through the carotids and the Circle of Willis.
    Type: Application
    Filed: April 30, 2014
    Publication date: November 20, 2014
    Applicant: BENECHILL, INC.
    Inventors: Denise Barbut, Alan Rozenberg, John K. Hoffman
  • Patent number: 8721699
    Abstract: A method for providing and adjusting cerebral cooling in response to changes in a physiological parameter. A spray having a boiling point between 38-300° C. is delivered to the surface of a patient's nasal cavities. The spray causes cooling by direct heat transfer through the nasopharynx and hematogenous cooling through the carotids and the Circle of Willis. A physiological parameter, such as cerebral temperature, changes in cerebral blood flow or brain oxygenation is monitored. The delivery rate of the spray is adjusted in response to the physiological parameter.
    Type: Grant
    Filed: February 10, 2010
    Date of Patent: May 13, 2014
    Assignee: BeneChill, Inc.
    Inventors: Denise Barbut, Allan Rozenberg, John K Hoffman
  • Publication number: 20130331915
    Abstract: A method for cerebral cooling is described using a cooling assembly, which includes first and second elongate tubular members adapted for insertion into a nasal cavity of a patient through the patient's nostrils. The elongate tubular members each have a proximal end, a distal end, a lumen extending therebetween, and a plurality of ports in fluid communication with the lumen. The cooling assembly also includes a manifold and a reservoir, which contains a pressurized fluid that includes a propellant having a boiling point less than 22° C. The elongate tubular members are inserted into the nasal cavity through the patient's nostrils and pressurized fluid is delivered onto a surface of the nasal cavity by infusing the pressurized fluid from the reservoir through the manifold, into the lumens and through the plurality of ports of the first and second elongate tubular members.
    Type: Application
    Filed: August 9, 2013
    Publication date: December 12, 2013
    Applicant: BeneChill, Inc.
    Inventors: ALLAN ROZENBERG, JOHN K. HOFFMAN, JAMES D. SAVAGE
  • Patent number: 8512280
    Abstract: A cerebral cooling device that uses a pressurized source to deliver a fluid that evaporates in the nasal cavity to provide cooling and has a balloon on the distal end that inflates from some of the pressure front the pressurized source. The device includes a nasal catheter having delivery ports located in the distal region and a balloon on the distal end. The proximal end of the catheter is in fluid communication with a pressurized source of a low boiling point fluid. A manifold located between the pressurized source and the catheter distributes the fluid and pressure from the pressurized source to a first lumen of the catheter to inflate the balloon and to a second lumen of the catheter through the delivery ports to cool the nasal cavity. A check valve in the manifold ensures that the fluid and pressure are first delivered to the balloon.
    Type: Grant
    Filed: April 4, 2012
    Date of Patent: August 20, 2013
    Assignee: BeneChill, Inc.
    Inventors: Allan Rozenberg, John K Hoffman, James Savage
  • Patent number: 8480723
    Abstract: A method for cerebral and systemic cooling by providing a nebulized liquid having a boiling point of 38-300° C. The nebulized liquid is delivered as a mist or a spray via the nasal and/or oral cavities of a patient. The mist causes cooling by direct heat transfer through the nasopharynx and hematogenous cooling through the carotids and the Circle of Willis. Compositions and medical devices for cerebral and systemic cooling are also provided. Cooling assemblies, and methods of use, are also provided that include flexible balloon assemblies that are inserted to various locations in a patient's body. The flexible balloons are then infused with a liquid having a temperature between about ?20° C. and about 37° C. The flexible balloon assemblies can be inserted into the nasal cavity, oral cavity, throat, stomach, and other locations to effect cerebral cooling.
    Type: Grant
    Filed: April 11, 2008
    Date of Patent: July 9, 2013
    Assignee: BeneChill, Inc.
    Inventors: Denise Barbut, Allan Rozenberg, John K. Hoffman
  • Patent number: 8308786
    Abstract: A method for cerebral and systemic cooling by circulating a cold liquid through a nasal catheter looped through the patient's nasal cavities and around the nasal septum. The nasal catheter is inserted into the patient's first nostril, advanced through the nasal cavity, around the nasal septum and out of the patient's second nostril. A cold fluid having a temperature between about ?20° C. and about 37° C. is flowed though a lumen in the nasal catheter to cool the nasal cavity. The nasal catheter may have one or more flexible balloons mounted on the catheter such that when the catheter is looped around the nasal septum, the balloon(s) are positioned in a portion of the patient's first and second nasal cavities. When a cold liquid is circulated through the catheter lumen, the flexible balloons expand to a contact the inner walls of the nasal cavities and provide direct cooling of the nasal cavities.
    Type: Grant
    Filed: February 27, 2008
    Date of Patent: November 13, 2012
    Assignee: BeneChill, Inc.
    Inventors: Allan Rozenberg, Denise Barbut, John K. Hoffman
  • Publication number: 20120197362
    Abstract: A cerebral cooling device that uses a pressurized source to deliver a fluid that evaporates in the nasal cavity to provide cooling and has a balloon on the distal end that inflates from some of the pressure front the pressurized source. The device includes a nasal catheter having delivery ports located in the distal region and a balloon on the distal end. The proximal end of the catheter is in fluid communication with a pressurized source of a low boiling point fluid. A manifold located between the pressurized source and the catheter distributes the fluid and pressure from the pressurized source to a first lumen of the catheter to inflate the balloon and to a second lumen of the catheter through the delivery ports to cool the nasal cavity. A check valve in the manifold ensures that the fluid and pressure are first delivered to the balloon.
    Type: Application
    Filed: April 4, 2012
    Publication date: August 2, 2012
    Inventors: ALLAN ROZENBERG, John K. Hoffman, James Savage
  • Patent number: 8157767
    Abstract: A cerebral cooling device that uses a pressurized source to deliver a fluid that evaporates in the nasal cavity to provide cooling and has a balloon on the distal end that inflates from some of the pressure from the pressurized source. The device includes a nasal catheter having delivery ports located in the distal region and a balloon on the distal end. The proximal end of the catheter is in fluid communication with a pressurized source of a low boiling point fluid. A manifold located between the pressurized source and the catheter distributes the fluid and pressure from the pressurized source to a first lumen of the catheter to inflate the balloon and to a second lumen of the catheter through the delivery ports to cool the nasal cavity. A check valve in the manifold ensures that the fluid and pressure are first delivered to the balloon.
    Type: Grant
    Filed: June 18, 2010
    Date of Patent: April 17, 2012
    Assignee: BeneChill, Inc.
    Inventors: Allan Rozenberg, John K Hoffman, James Savage
  • Publication number: 20100324483
    Abstract: A cerebral cooling device that uses a pressurized source to deliver a fluid that evaporates in the nasal cavity to provide cooling and has a balloon on the distal end that inflates from some of the pressure from the pressurized source. The device includes a nasal catheter having delivery ports located in the distal region and a balloon on the distal end. The proximal end of the catheter is in fluid communication with a pressurized source of a low boiling point fluid. A manifold located between the pressurized source and the catheter distributes the fluid and pressure from the pressurized source to a first lumen of the catheter to inflate the balloon and to a second lumen of the catheter through the delivery ports to cool the nasal cavity. A check valve in the manifold ensures that the fluid and pressure are first delivered to the balloon.
    Type: Application
    Filed: June 18, 2010
    Publication date: December 23, 2010
    Inventors: ALLAN ROZENBERG, John K. Hoffman, James Savage
  • Patent number: 7824436
    Abstract: A method for cerebral and systemic cooling by providing a nebulized liquid having a boiling point of 38-300° C. The nebulized liquid is delivered as a mist or a spray via the nasal and/or oral cavities of a patient. The mist causes cooling by direct heat transfer through the nasopharynx and hematogenous cooling through the carotids and the Circle of Willis. Compositions and medical devices for cerebral and systemic cooling are also provided. Cooling assemblies, and methods of use, are also provided that include flexible balloon assemblies that are inserted to various locations in a patient's body. The flexible balloons are then infused with a liquid having a temperature between about ?20° C. and about 37° C. The flexible balloon assemblies can be inserted into the nasal cavity, oral cavity, throat, stomach, and other locations to effect cerebral cooling.
    Type: Grant
    Filed: May 10, 2006
    Date of Patent: November 2, 2010
    Assignee: BeneChill, Inc.
    Inventors: Denise Barbut, Allan Rozenberg, John K. Hoffman
  • Publication number: 20100211140
    Abstract: A method for providing and adjusting cerebral cooling in response to changes in a physiological parameter. A spray having a boiling point between 38-300° C. is delivered to the surface of a patient's nasal cavities. The spray causes cooling by direct heat transfer through the nasopharynx and hematogenous cooling through the carotids and the Circle of Willis. A physiological parameter, such as cerebral temperature, changes in cerebral blood flow or brain oxygenation is monitored. The delivery rate of the spray is adjusted in response to the physiological parameter.
    Type: Application
    Filed: February 10, 2010
    Publication date: August 19, 2010
    Inventors: DENISE BARBUT, Allan Rozenberg, John K. Hoffman
  • Publication number: 20080249188
    Abstract: A method for cerebral and systemic cooling by providing a nebulized liquid having a boiling point of 38-300° C. The nebulized liquid is delivered as a mist or a spray via the nasal and/or oral cavities of a patient. The mist causes cooling by direct heat transfer through the nasopharynx and hematogenous cooling through the carotids and the Circle of Willis. Compositions and medical devices for cerebral and systemic cooling are also provided. Cooling assemblies, and methods of use, are also provided that include flexible balloon assemblies that are inserted to various locations in a patient's body. The flexible balloons are then infused with a liquid having a temperature between about ?20° C. and about 37° C. The flexible balloon assemblies can be inserted into the nasal cavity, oral cavity, throat, stomach, and other locations to effect cerebral cooling.
    Type: Application
    Filed: April 11, 2008
    Publication date: October 9, 2008
    Inventors: Denise Barbut, Allan Rozenberg, John K. Hoffman
  • Publication number: 20080215002
    Abstract: A method for cerebral and systemic cooling by circulating a cold liquid through a nasal catheter looped through the patient's nasal cavities and around the nasal septum. The nasal catheter is inserted into the patient's first nostril, advanced through the nasal cavity, around the nasal septum and out of the patient's second nostril. A cold fluid having a temperature between about ?20° C. and about 37° C. is flowed though a lumen in the nasal catheter to cool the nasal cavity. The nasal catheter may have one or more flexible balloons mounted on the catheter such that when the catheter is looped around the nasal septum, the balloon(s) are positioned in a portion of the patient's first and second nasal cavities. When a cold liquid is circulated through the catheter lumen, the flexible balloons expand to a contact the inner walls of the nasal cavities and provide direct cooling of the nasal cavities.
    Type: Application
    Filed: February 27, 2008
    Publication date: September 4, 2008
    Inventors: Allan Rozenberg, Denise Barbut, John K. Hoffman
  • Publication number: 20020153010
    Abstract: A liquid ventilation apparatus and method for facilitating liquid breathing by a patient. The apparatus can include a pressurizable chamber adapted to contain a breathable liquid and a gas, such that pressurizing and depressurizing the chamber moves a breathable liquid into and out of the lungs of a patient.
    Type: Application
    Filed: April 23, 2001
    Publication date: October 24, 2002
    Inventors: Allan L. Rozenberg, John K. Hoffman