Patents by Inventor John Kao

John Kao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12600953
    Abstract: The present application is directed to compositions and methods for establishing organoid cultures from cryogenically preserved tissue (e.g., human biopsy tissue), and related methods of use with such established organoid cultures.
    Type: Grant
    Filed: July 27, 2018
    Date of Patent: April 14, 2026
    Assignee: The Regents of the University of Michigan
    Inventors: Jason Spence, Yu-Hwai Tsai, Michael Czerwinski, John Kao
  • Publication number: 20210087532
    Abstract: The present application is directed to compositions and methods for establishing organoid cultures from cryogenically preserved tissue (e.g., human biopsy tissue), and related methods of use with such established organoid cultures.
    Type: Application
    Filed: July 27, 2018
    Publication date: March 25, 2021
    Inventors: Jason SPENCE, Yu-Hwai TSAI, Michael CZERWINSKI, John KAO
  • Publication number: 20190249189
    Abstract: The present invention provides gene targets, constructs and methods for the genetic control of plant disease caused by multiple plant viruses. The present invention relates to achieving a plant protective effect through the identification of target coding sequences and the use of recombinant DNA technologies for post-transcriptionally repressing or inhibiting expression of the target coding sequences of plant-parasitic viruses. Protein-expression based approaches may also be utilized to augment phenotype resistance. Thus, transcription of a single transgenic event comprising one or more plant expression cassettes can allow for broad spectrum resistance of a plant to multiple plant viral strains and species among the geminiviruses, tospoviruses, and potexviruses.
    Type: Application
    Filed: February 19, 2019
    Publication date: August 15, 2019
    Inventors: Shihshieh Huang, Stanislaw Flasinski, Alessandra Frizzi, Brad Gabor, Charles Hagen, John Kao, Raquel Salati
  • Publication number: 20170356004
    Abstract: The present invention provides gene targets, constructs and methods for the genetic control of plant disease caused by multiple plant viruses. The present invention relates to achieving a plant protective effect through the identification of target coding sequences and the use of recombinant DNA technologies for post-transcriptionally repressing or inhibiting expression of the target coding sequences of plant-parasitic viruses. Protein-expression based approaches may also be utilized to augment phenotype resistance. Thus, transcription of a single transgenic event comprising one or more plant expression cassettes can allow for broad spectrum resistance of a plant to multiple plant viral strains and species among the geminiviruses, tospoviruses, and potexviruses.
    Type: Application
    Filed: May 17, 2017
    Publication date: December 14, 2017
    Inventors: Shihshieh Huang, Stanislaw Flasinski, Alessandra Frizzi, Brad Gabor, Charles Hagen, John Kao, Raquel Salati
  • Patent number: 9670502
    Abstract: The present invention provides gene targets, constructs and methods for the genetic control of plant disease caused by multiple plant viruses. The present invention relates to achieving a plant protective effect through the identification of target coding sequences and the use of recombinant DNA technologies for post-transcriptionally repressing or inhibiting expression of the target coding sequences of plant-parasitic viruses. Protein-expression based approaches may also be utilized to augment phenotype resistance. Thus, transcription of a single transgenic event comprising one or more plant expression cassettes can allow for broad spectrum resistance of a plant to multiple plant viral strains and species among the geminiviruses, tospoviruses, and potexviruses.
    Type: Grant
    Filed: January 25, 2013
    Date of Patent: June 6, 2017
    Assignee: Monsanto Technology LLC
    Inventors: Shihshieh Huang, Stanislaw Flasinski, Alessandra Frizzi, Brad Gabor, Charles Hagen, John Kao, Raquel Salati
  • Patent number: 8802939
    Abstract: The present invention relates to novel methods of producing interspecific hybrids between C. annuum and C. pubescens and progeny thereof. In addition, the present invention provides for the hybrid pepper plants, and parts thereof including their fruit, tissues, and seeds, resulting from a cross between C. annuum and C. pubescens that have nuclear genetic material from both C. annuum and C. pubescens. The hybrid pepper plants of the invention may have a variety of traits including resistance to geminiviruses, tobamoviruses, and resistance to damage by Xanthomonas.
    Type: Grant
    Filed: August 27, 2009
    Date of Patent: August 12, 2014
    Assignee: Seminis Vegetable Seeds, Inc.
    Inventors: Chuong Phan, John Kao, Terry Berke, Carl Jones
  • Patent number: 8455716
    Abstract: The present invention provides gene targets, constructs and methods for the genetic control of plant disease caused by multiple plant viruses. The present invention relates to achieving a plant protective effect through the identification of target coding sequences and the use of recombinant DNA technologies for post-transcriptionally repressing or inhibiting expression of the target coding sequences of plant-parasitic viruses. Protein-expression based approaches may also be utilized to augment phenotype resistance. Thus, transcription of a single transgenic event comprising one or more plant expression cassettes can allow for broad spectrum resistance of a plant to multiple plant viral strains and species among the geminiviruses, tospoviruses, and potexviruses.
    Type: Grant
    Filed: April 20, 2010
    Date of Patent: June 4, 2013
    Assignee: Monsanto Technology LLC
    Inventors: Shihshieh Huang, Stanislaw Flasinski, Alessandra Frizzi, Brad Gabor, Charles Hagen, John Kao, Raquel Salati
  • Patent number: 8288617
    Abstract: A squash plant having high level geminivirus resistance and a method for developing a squash plant having high resistance to geminvirus.
    Type: Grant
    Filed: August 25, 2008
    Date of Patent: October 16, 2012
    Assignee: Seminis Vegetable Seeds, Inc.
    Inventors: William C Johnson, John Kao
  • Publication number: 20100269224
    Abstract: The present invention provides gene targets, constructs and methods for the genetic control of plant disease caused by multiple plant viruses. The present invention relates to achieving a plant protective effect through the identification of target coding sequences and the use of recombinant DNA technologies for post-transcriptionally repressing or inhibiting expression of the target coding sequences of plant-parasitic viruses. Protein-expression based approaches may also be utilized to augment phenotype resistance. Thus, transcription of a single transgenic event comprising one or more plant expression cassettes can allow for broad spectrum resistance of a plant to multiple plant viral strains and species among the geminiviruses, tospoviruses, and potexviruses.
    Type: Application
    Filed: April 20, 2010
    Publication date: October 21, 2010
    Inventors: Shihshieh Huang, Stanislaw Flasinski, Alessandra Frizzi, Brad Gabor, Charles Hagen, John Kao, Raquel Salati
  • Publication number: 20100058494
    Abstract: The present invention relates to novel methods of producing interspecific hybrids between C. annuum and C. pubescens and progeny thereof. In addition, the present invention provides for the hybrid pepper plants, and parts thereof including their fruit, tissues, and seeds, resulting from a cross between C. annuum and C. pubescens that have nuclear genetic material from both C. annuum and C. pubescens. The hybrid pepper plants of the invention may have a variety of traits including resistance to geminiviruses, tobamoviruses, and resistance to damage by Xanthomonas.
    Type: Application
    Filed: August 27, 2009
    Publication date: March 4, 2010
    Inventors: Chuong Phan, John Kao, Terry Berke, Carl Jones
  • Publication number: 20080320614
    Abstract: A squash plant having high level geminivirus resistance and a method for developing a squash plant having high resistance to geminvirus.
    Type: Application
    Filed: August 25, 2008
    Publication date: December 25, 2008
    Inventors: William C. Johnson, John Kao
  • Patent number: 7432420
    Abstract: A squash plant having high level geminivirus resistance and a method for developing a squash plant having high resistance to geminvirus.
    Type: Grant
    Filed: September 7, 2005
    Date of Patent: October 7, 2008
    Assignee: Seminis Vegetable Seeds, Inc.
    Inventors: William C Johnson, John Kao
  • Patent number: 7386539
    Abstract: A system for customized document portfolio management. Corresponding methods and user interfaces are provided accordingly for allowing customized document portfolio management. In an preferred embodiment the system includes a document metadata database storing a plurality of documents and meta information thereof, a management server programmed to rule engine, search, security engine and notification engines, and a web server providing an interactive website for displaying documents and allowing creation of a customized portfolio. The customized portfolio management system preferably provides notification on the website, apprising users of changes in the status of their documents. Unique technical identification codes may be used to establish relationships among document.
    Type: Grant
    Filed: January 10, 2003
    Date of Patent: June 10, 2008
    Assignee: Taiwan Semiconductor Manufacturing Company, Ltd.
    Inventors: Lup Cheong Patrick Hung, John Kao, Frank Sung, Yu-Jen Chen, Edwin D. Liou, Ming-Hsin Thomas Chen, Jeffrey Liou, Yu Yong Shen, Chun-Cho Chen
  • Patent number: 7254588
    Abstract: A document management system generates a hierarchical category tree itemizing documents within a database from associated attributes of the documents. The document management system further provides access privileges to the documents itemized in the hierarchical category tree by associating access privileges to the attributes of the documents with itemized by the hierarchical category tree.
    Type: Grant
    Filed: April 26, 2004
    Date of Patent: August 7, 2007
    Assignee: Taiwan Semiconductor Manufacturing Company, Ltd.
    Inventors: Feng-Kuang Sung, John Kao, Ching-Chung Chang, Cheng-Hui Chiu
  • Publication number: 20070056059
    Abstract: A squash plant having high level geminivirus resistance and a method for ash plant having high resistance to geminvirus.
    Type: Application
    Filed: September 7, 2005
    Publication date: March 8, 2007
    Inventors: William Johnson, John Kao
  • Publication number: 20060122843
    Abstract: A computer controlled system and method of using the system for control of shipping a quantity of product either domestically or internationally. The system comprises a number of user input stations for entering a shipping request. Product release information stored in the computer is added to the request which is transmitted t a product storage unit, a printer, and an exit control station. The product storage unit selects the product requested. The printer prints a product release form which can include a customs declaration form and/or a digital authentication stamp if desired. The product is prepared for shipping and the product release form is attached. The product and the product release form is checked at the exit control station. The product is then shipped or corrective action is taken.
    Type: Application
    Filed: January 28, 2002
    Publication date: June 8, 2006
    Inventors: Hsiu-Chu Lin, Yi-Sung Lin, Chi-Wen Lin, John Kao
  • Publication number: 20050240572
    Abstract: A document management system generates a hierarchical category tree itemizing documents within a database from associated attributes of the documents. The document management system further provides access privileges to the documents itemized in the hierarchical category tree by associating access privileges to the attributes of the documents with itemized by the hierarchical category tree.
    Type: Application
    Filed: April 26, 2004
    Publication date: October 27, 2005
    Inventors: Feng-Kuang Sung, John Kao, Ching-Chung Chang, Cheng-Hui Chiu
  • Publication number: 20050209669
    Abstract: A positioning system for use in placing a stent at a vascular bifurcation includes an elongated catheter having an inflatable balloon mounted at its distal end. With the balloon deflated, the catheter/balloon assembly is engageable with the stent allowing the stent to be advanced through the vasculature to the bifurcation. At the bifurcation, the balloon can be selectively inflated to release the stent. A plurality of individually activatable, acoustic transducer crystals is mounted on the catheter at the proximal end of the stent. Each crystal can be selectively activated from an extracorporeal location to radiate an acoustic signal that is directed toward a vessel wall where it is reflected, creating an acoustic return signal. The return signal is then received by the respective transmitting crystal and converted to an electrical signal. The electrical signals are then used to determine a spatial relationship between the stent and the bifurcation.
    Type: Application
    Filed: March 3, 2004
    Publication date: September 22, 2005
    Inventor: John Kao
  • Publication number: 20040107214
    Abstract: A system for customizing a design portfolio for an IC product. An IP library management server allows IP providers to upload IP libraries and subsequently verify and sort the uploaded IP libraries. A technology document server allows a foundry to upload technology documents and verify and sort the uploaded technology document. A database stores the verified technology documents, IP libraries, and meta information associated therewith. A design portfolio management server provides a terminal user the verified technology documents and IP libraries for creation of a customized design portfolio thereby and further monitoring the customized design portfolio to send notification when the portfolio status changes.
    Type: Application
    Filed: January 10, 2003
    Publication date: June 3, 2004
    Inventors: Lup Cheong Patrick Hung, Ming-Hsin Thomas Chen, Feng-Mei Yang, Yu Yong Shen, Chun-Cho Chen, Yu-Jen Chen, Edwin D. Liou, Jeffrey Liou, John Kao, Frank Sung
  • Publication number: 20040107175
    Abstract: A system for customized document portfolio management. Corresponding methods and user interfaces are provided accordingly for allowing customized document portfolio management. In an preferred embodiment the system includes a document metadata database storing a plurality of documents and meta information thereof, a management server programmed to rule engine, search, security engine and notification engines, and a web server providing an interactive website for displaying documents and allowing creation of a customized portfolio. The customized portfolio management system preferably provides notification on the website, apprising users of changes in the status of their documents. Unique technical identification codes may be used to establish relationships among document.
    Type: Application
    Filed: January 10, 2003
    Publication date: June 3, 2004
    Inventors: Lup Cheong Patrick Hung, John Kao, Frank Sung, Yu-Jen Chen, Edwin D. Liou, Ming-Hsin Thomas Chen, Jeffrey Liou, Yu Yong Shen, Chun-Cho Chen