Patents by Inventor John Kenten

John Kenten has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ELECTROCHEMILUMINESCENT LABELED PROBES FOR USE IN IMMUNOASSAY METHODS, METHODS USING SUCH AND KITS COMPRISING SAME
    Publication number: 20260266808
    Abstract: The present invention is directed to assay methods and compounds and kits used in such assays.
    Type: Application
    Filed: January 20, 2026
    Publication date: September 10, 2026
    Inventors: John KENTEN, Mikayla HIGGINS, George SIGAL
  • Methods, compositions, and kits for assay signal amplification
    Patent number: 12704459
    Abstract: The invention relates to methods, compositions, kits, and assay systems for assay signal amplification. Also provided herein is a signal amplification reagent, wherein the signal amplification reagent is an antibody or antigen-binding fragment thereof.
    Type: Grant
    Filed: June 27, 2022
    Date of Patent: August 11, 2026
    Assignee: MESO SCALE TECHNOLOGIES, LLC.
    Inventors: John Kenten, George Sigal, Alexander K. Tucker-Schwartz
  • KIDNEY FUNCTION BIOMARKERS
    Publication number: 20260227415
    Abstract: The present invention relates to methods of diagnosing a kidney disorder in a patient, as well as methods of monitoring the progression of a kidney disorder and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.
    Type: Application
    Filed: March 27, 2026
    Publication date: August 6, 2026
    Applicant: Meso Scale Technologies, LLC.
    Inventors: Eli N. Glezer, John Kenten, Sudeep Kumar, Galina Nikolenko
  • Electrochemiluminescent labeled probes for use in immunoassay methods, methods using such and kits comprising same
    Patent number: 12553887
    Abstract: The present invention is directed to assay methods and compounds and kits used in such assays.
    Type: Grant
    Filed: February 28, 2020
    Date of Patent: February 17, 2026
    Assignee: MESO SCALE TECHNOLOGIES, LLC.
    Inventors: John Kenten, Mikayla Higgins, George Sigal
  • ASSAY METHODS
    Publication number: 20250362291
    Abstract: The present invention is directed to methods for improving assay specificity and performance in binding assays.
    Type: Application
    Filed: August 8, 2025
    Publication date: November 27, 2025
    Inventors: Anahit AGHVANYAN, Eli N. GLEZER, John KENTEN, George SIGAL, Martin STENGELIN, David ROUTENBERG
  • Assay methods
    Patent number: 12411131
    Abstract: The present invention is directed to methods for improving assay specificity and performance in binding assays.
    Type: Grant
    Filed: July 21, 2022
    Date of Patent: September 9, 2025
    Assignee: MESO SCALE TECHNOLOGIES, LLC.
    Inventors: Anahit Aghvanyan, Eli N. Glezer, John Kenten, George Sigal, Martin Stengelin, David Routenberg
  • METHODS AND KITS FOR VIRUS DETECTION
    Publication number: 20250237661
    Abstract: The invention relates to methods and kits for detecting a virus, e.g., a respiratory virus such as a coronavirus, in a biological sample. The invention also relates to methods and kits for detecting and/or quantifying biomarkers, e.g., antibody biomarkers against a viral antigen; inflammatory and/or tissue damage response biomarkers; and/or extracellular vesicles in response to a viral infection.
    Type: Application
    Filed: December 2, 2024
    Publication date: July 24, 2025
    Inventors: Jacob N. WOHLSTADTER, George SIGAL, Anu MATHEW, Anastasia AKSYUK, David ROUTENBERG, Martin STENGELIN, John KENTEN, Timothy J. BREAK, Seth B. HARKINS, Michael TSIONSKY
  • ASSAY METHODS
    Publication number: 20250060361
    Abstract: The present invention is directed to methods for improving assay specificity and performance in binding assays.
    Type: Application
    Filed: November 6, 2024
    Publication date: February 20, 2025
    Inventors: Anahit AGHVANYAN, Eli N. GLEZER, John KENTEN, George SIGAL, Martin STENGELIN
  • GLOMERULONEPHRITIS BIOMARKERS
    Publication number: 20250020662
    Abstract: The present invention relates to methods of diagnosing glomerulonephritis (GN) in a patient, as well as methods of monitoring the progression of GN and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.
    Type: Application
    Filed: March 27, 2024
    Publication date: January 16, 2025
    Applicant: Meso Scale Technologies, LLC.
    Inventors: Eli N. Glezer, John Kenten, Galina Nikolenko
  • Assay methods
    Patent number: 12163954
    Abstract: The present invention is directed to methods for improving assay specificity and performance in binding assays.
    Type: Grant
    Filed: December 23, 2020
    Date of Patent: December 10, 2024
    Assignee: MESO SCALE TECHNOLOGIES, LLC.
    Inventors: Anahit Aghvanyan, Eli N. Glezer, John Kenten, George Sigal, Martin Stengelin
  • LUNG CANCER BIOMARKERS
    Publication number: 20240361322
    Abstract: The present invention relates to methods of diagnosing lung cancer in a patient, as well as methods of monitoring the progression of lung cancer and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.
    Type: Application
    Filed: December 13, 2023
    Publication date: October 31, 2024
    Applicant: Meso Scale Technologies, LLC.
    Inventors: Anahit Aghvanyan, Eli N. Glezer, John Kenten, Sudeep Kumar, Galina Nikolenko, Martin Stengelin
  • ASSAY METHODS AND KITS
    Publication number: 20240229110
    Abstract: The invention provides novel components for conducting assays, e.g., sandwich immunoassays, methods utilizing the novel components, and compositions and kits comprising the novel components.
    Type: Application
    Filed: December 19, 2023
    Publication date: July 11, 2024
    Inventors: John KENTEN, Galina NIKOLENKO, John Robert PETTERSSON
  • SYSTEM AND METHOD FOR CONDUCTING A MULTIPLEXED ASSAY
    Publication number: 20240159746
    Abstract: Described herein are methods, systems and kits for conducting an assay for one or more analytes of interest in a sample. In one aspect, a method is provided for conducting a multiplexed binding assay for a plurality of analytes of interest in a sample. In one aspect, the assay includes an analyte binding step and a detection step. In one aspect, the analyte binding step is separated from the detection step.
    Type: Application
    Filed: February 28, 2022
    Publication date: May 16, 2024
    Inventors: Michael TSIONSKY, John KENTEN
  • Glomerulonephritis biomarkers
    Patent number: 11971418
    Abstract: The present invention relates to methods of diagnosing glomerulonephritis (GN) in a patient, as well as methods of monitoring the progression of GN and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.
    Type: Grant
    Filed: February 8, 2021
    Date of Patent: April 30, 2024
    Assignee: Meso Scale Technologies, LLC.
    Inventors: Eli N. Glezer, John Kenten, Galina Nikolenko
  • Biodosimetry panels and methods
    Patent number: 11967410
    Abstract: Methods and kits to assess an absorbed dose of ionizing radiation and/or the severity of tissue injury from radiation in a patient. Also, algorithms used to calculate an absorbed dose of radiation based on biomarker measurements of a plurality of biomarkers that are altered relative to a normal control in the event of radiation exposure.
    Type: Grant
    Filed: February 22, 2018
    Date of Patent: April 23, 2024
    Assignees: Meso Scale Technologies, LLC, THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC.
    Inventors: William F Blakely, Eli N. Glezer, John Kenten, Sudeep Kumar, Anu Mathew, Natalia I. Ossetrova, George Sigal
  • KIDNEY FUNCTION BIOMARKERS
    Publication number: 20240053364
    Abstract: The present invention relates to methods of diagnosing a kidney disorder in a patient, as well as methods of monitoring the progression of a kidney disorder and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.
    Type: Application
    Filed: March 27, 2023
    Publication date: February 15, 2024
    Applicant: Meso Scale Technologies, LLC.
    Inventors: Eli N. Glezer, John Kenten, Sudeep Kumar, Galina Nikolenko
  • LUNG CANCER BIOMARKERS
    Publication number: 20240027456
    Abstract: The present invention relates to methods of diagnosing lung cancer in a patient, as well as methods of monitoring the progression of lung cancer and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.
    Type: Application
    Filed: October 4, 2023
    Publication date: January 25, 2024
    Applicant: Meso Scale Technologies, LLC.
    Inventors: Anahit Aghvanyan, Eli N. Glezer, John Kenten, Sudeep Kumar, Galina Nikolenko, Martin Stengelin, Srikant Vaithilingam
  • METHODS, COMPOSITIONS, AND KITS FOR NUCLEIC ACID DETECTION
    Publication number: 20240018571
    Abstract: The invention relates to methods, oligonucleotide reagents, compositions, and kits for nucleic acid detection.
    Type: Application
    Filed: May 18, 2021
    Publication date: January 18, 2024
    Inventors: John KENTEN, Jacob N. WOHLSTADTER
  • Lung cancer biomarkers
    Patent number: 11802877
    Abstract: The present invention relates to methods of diagnosing lung cancer in a patient, as well as methods of monitoring the progression of lung cancer and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.
    Type: Grant
    Filed: May 26, 2020
    Date of Patent: October 31, 2023
    Assignee: MESO SCALE TECHNOLOGIES, LLC.
    Inventors: Anahit Aghvanyan, Eli N. Glezer, John Kenten, Sudeep Kumar, Galina Nikolenko, Martin Stengelin, Srikant Vaithilingam
  • COMPOSITIONS AND METHODS FOR ASSAY MEASUREMENTS
    Publication number: 20230279290
    Abstract: The disclosure relates to novel compositions comprising an electrochemiluminescence (ECL) co-reactant. In embodiments, the composition further comprises an ionic component, a surfactant, or combination thereof. In embodiments, the ECL co-reactant is triethanolamine (TEA), tert-butyldiethanolamine (tBDEA), methyldibutylethanolamine (MDEA), 3-[Bis-(2-hydroxy-ethyl)-amino]-propane-1-sulfonic acid (DEA-PS), or a combination thereof. Methods of using the compositions and kits comprising the compositions are also provided herein, including methods using ECL-labeled oligonucleotide probes having quenching moieties.
    Type: Application
    Filed: December 22, 2022
    Publication date: September 7, 2023
    Inventors: John Kenten, John Pettersson, George Sigal, Alexander K. Tucker-Schwartz