Abstract: Examples of the present disclosure provide apparatuses and methods for direct data transfer. An example method comprises transferring data between a first device and a second device, wherein the first device is a bit vector operation device, and transforming the data using a data transform engine (DTE) by rearranging the data to enable the data to be stored on the first device when transferring the data between the second device and first memory device.

Abstract: Systems and methods are provided to generate subscription recommendations within a membership platform based on classification of content creators. Exemplary implementations may: obtain creator information for content creators of a membership platform; classify individual content creators into modality classes based on the creator information; classify individual content creators into genre classes based on the creator information; generate relationship information establishing relationships between the content creators based on commonality within the modality classes and the genre classes; generate one or more subscription recommendations based on the relationship information; effectuate presentation of the one or more subscription recommendations on one or more computing platforms of one or more of the subscribers; and/or perform other operations.

Abstract: Systems and methods to generate creator page recommendations for content creators within a membership platform based on classification of content creators are described herein. Exemplary implementations may: obtain new creator information; obtain existing creator information; classify individual existing content creators into modality classes and/or genre classes based on the existing creator information; classify individual new content creators into the modality classes and/or the genre classes based on the new creator information; generate relationship information establishing relationships between the new content creators and the existing content creators; generate one or more creator page recommendations based on the relationship information; effectuate presentation of the one or more creator page recommendations; and/or perform other operations.

Abstract: Systems and methods to generate creator page recommendations for content creators within a membership platform based on classification of content creators are described herein. Exemplary implementations may: obtain new creator information; obtain existing creator information; classify individual existing content creators into modality classes and/or genre classes based on the existing creator information; classify individual new content creators into the modality classes and/or the genre classes based on the new creator information; generate relationship information establishing relationships between the new content creators and the existing content creators; generate one or more creator page recommendations based on the relationship information; effectuate presentation of the one or more creator page recommendations; and/or perform other operations.

Abstract: Systems and methods to generate creator page recommendations for content creators within a membership platform based on classification of content creators are described herein. Exemplary implementations may: obtain new creator information; obtain existing creator information; classify individual existing content creators into modality classes and/or genre classes based on the existing creator information; classify individual new content creators into the modality classes and/or the genre classes based on the new creator information; generate relationship information establishing relationships between the new content creators and the existing content creators; generate one or more creator page recommendations based on the relationship information; effectuate presentation of the one or more creator page recommendations; and/or perform other operations.

Abstract: Systems and methods to generate creator page recommendations for content creators within a membership platform based on classification of content creators are described herein. Exemplary implementations may: obtain new creator information; obtain existing creator information; classify individual existing content creators into modality classes and/or genre classes based on the existing creator information; classify individual new content creators into the modality classes and/or the genre classes based on the new creator information; generate relationship information establishing relationships between the new content creators and the existing content creators; generate one or more creator page recommendations based on the relationship information; effectuate presentation of the one or more creator page recommendations; and/or perform other operations.

Abstract: Systems and techniques for determining degree of motion using machine learning to improve medical image quality are presented. In one example, a system generates, based on a convolutional neural network, motion probability data indicative of a probability distribution of a degree of motion for medical imaging data generated by a medical imaging device. The system also determines motion score data for the medical imaging data based on the motion probability data.

Abstract: Extended-release formulations can be prepared that comprise a core and an optional coating layer formed over the core. The core comprises a therapeutically effective amount an active pharmaceutical ingredient (API), a non-swelling matrix forming agent comprising a water-soluble agent and a water-insoluble polymer; one or more extended-release agents; an optional, wicking agent; and one or more optional excipients. Such formulations may be useful for preparing extended-release formulations of pregabalin that are suitable for once-daily dosing for the treatment of neuropathic pain associated with diabetic peripheral neuropathy (DPN) or postherpetic neuralgia (PHN).

Abstract: Systems and techniques for determining degree of motion using machine learning to improve medical image quality are presented. In one example, a system generates, based on a convolutional neural network, motion probability data indicative of a probability distribution of a degree of motion for medical imaging data generated by a medical imaging device. The system also determines motion score data for the medical imaging data based on the motion probability data.

Abstract: Sugar alcohol-free formulations of fingolimod. Compositions of fingolimod, salts thereof, or esters thereof that lack sugar alcohols are disclosed. The composition may include a water-soluble filler and a water-insoluble filler, in addition to other common excipients. In some examples, the water-soluble filler is glycine and the water-insoluble filler is dibasic calcium phosphate dihydrate as fillers. In some examples, the water-soluble filler and water-insoluble filler are present in equal concentrations. The compositions disclosed here may be used to make immediate release dosage forms containing fingolimod hydrochloride.

Abstract: In a method and apparatus for magnetic resonance imaging of an examination subject using an acquisition sequence that includes at least one acquisition cycle, wherein the acquisition cycle includes a readout block set with at least two readout blocks, and a saturation pulse set with at least two saturation pulses, the saturation pulses of the saturation pulse set are respectively associated with respective readout blocks of the readout block set, and the saturation pulses of the saturation pulse set have respectively varying flip angles.

Abstract: A method for optimizing Specific Absorption Rate (SAR) estimation using a Magnetic Resonance Imaging (MRI) Scanner includes detecting movement of a table holding a patient into a bore of the MRI Scanner and, while the table is moving into the bore, performing an MRI scan of the patient to acquire a multi-slice multi-dimensional MRI dataset of an anatomical region of interest of the patient. The multi-slice multi-dimensional MRI dataset is processed to obtain a three-dimensional model corresponding to the patient's body geometry. Then, a patient-optimized SAR estimation is calculated using the three-dimensional model of the patient's body geometry.

Abstract: A pharmaceutical composition comprising thyroxine, acacia, and an antioxidant selected from propyl gallate, butylated hydroxyanisol, and butylated hydroxytoluene is disclosed. The pharmaceutical composition has an improved shelf life. In one embodiment, the composition additionally comprises sucrose, microcrystalline cellulose, and mannitol. The pharmaceutical composition may be used for treating thyroid disorders by orally administering the composition to a patient in need thereof.

Abstract: In a method and apparatus for magnetic resonance imaging of an examination subject using an acquisition sequence that includes at least one acquisition cycle, wherein the acquisition cycle includes a readout block set with at least two readout blocks, and a saturation pulse set with at least two saturation pulses, the saturation pulses of the saturation pulse set are respectively associated with respective readout blocks of the readout block set, and the saturation pulses of the saturation pulse set have respectively varying flip angles.

Abstract: In a method and apparatus to generate a magnetic resonance (MR) image in a volume of interest of an examination subject, the magnetization is excited in an additional volume in the subject by at least one RF pulse, in order to achieve a desired magnetization in the volume of interest. The additional excitation volume differs at least partially from the volume of interest. For this purpose, at least one MR overview image of the examination subject is analyzed automatically to determine a position of at least one anatomical structure of the examination subject, from which the volume of interest is automatically determined. The additional excitation volume is automatically determined using the position of the at least one anatomical structure. The MR image in the volume of interest is acquired with excitation of the magnetization in the automatically determined additional excitation volume.

Abstract: A pharmaceutical composition comprising thyroxine, acacia, and an antioxidant selected from propyl gallate, butylated hydroxyanisol, and butylated hydroxytoluene is disclosed. The pharmaceutical composition has an improved shelf life. In one embodiment, the composition additionally comprises sucrose, microcrystalline cellulose, and mannitol. The pharmaceutical composition may be used for treating thyroid disorders by orally administering the composition to a patient in need thereof.

Abstract: A pharmaceutical composition comprising thyroxine and carrageenan. The pharmaceutical composition has an improved shelf life compared to other pharmaceutical compositions containing thyroxine. In one embodiment, the composition additionally comprises sucrose, microcrystalline cellulose, and mannitol. The pharmaceutical composition may be used for treating thyroid disorders by orally administering the composition to a patient in need thereof.

Abstract: In a method and apparatus to generate a magnetic resonance (MR) image in a volume of interest of an examination subject, the magnetization is excited in an additional volume in the subject by at least one RF pulse, in order to achieve a desired magnetization in the volume of interest. The additional excitation volume differs at least partially from the volume of interest. For this purpose, at least one MR overview image of the examination subject is analyzed automatically to determine a position of at least one anatomical structure of the examination subject, from which the volume of interest is automatically determined. The additional excitation volume is automatically determined using the position of the at least one anatomical structure. The MR image in the volume of interest is acquired with excitation of the magnetization in the automatically determined additional excitation volume.

Abstract: The present invention relates to a fixator for aligning and setting a fractured bone with an internal canal, such as a Colles' fracture of the radius. The fixator includes two positioning wires and at least one pinball fastener. An elongated portion of each wire is inserted through either the radial styloid process or the dorso-ulnar cortex and into the intramedullary canal. A shaped portion of each wire extends from the wrist. The lateral portion of the shaped portions are coplanar when viewed from above and their overlapping portions are in side-by-side relation when viewed from the side. The external portions are also preferably curved with concentric overlapping portions so that the fixator resembles a bracelet. When necessary, the fixator includes additional interfragmentary stabilizing wires that are securely joined to the positioning wires. Crimp sleeves can be used in conjunction with the pinballs to securely join the wires.

Abstract: Disclosed are compositions and methods for preventing, inhibiting, reducing and treating conditions and diseases associated with abnormal bone resorption in mammals, including for example osteoporosis. Embodiments of compositions of the invention comprise a pharmaceutically effective amount of alendronate and vitamin D3 suitable for once-weekly dosing. Compositions and methods of the invention provide vitamin D nutrition during bisphosphonate treatment to facilitate normal bone formation and mineralization while minimizing the occurrence of or potential for the complications associated with vitamin D insufficiency, such as hypocalcaemia and osteomalacia. Also disclosed are methods for manufacturing compositions of the present invention, for measuring stability and degradation of those compositions, and for measuring blood plasma levels of vitamin D.