Patents by Inventor John Kopchick

John Kopchick has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11433117
    Abstract: Methods and FSP27 compositions for treating and/or preventing metabolic disease and conditions associated insulin resistance, obesity, inflammation and dyslipidemia are described.
    Type: Grant
    Filed: June 14, 2018
    Date of Patent: September 6, 2022
    Assignee: Ohio University
    Inventors: Vishwajeet Puri, John Kopchick, Vishva Sharma
  • Patent number: 11426445
    Abstract: FSP27 compositions and methods for treating cancers are described.
    Type: Grant
    Filed: September 17, 2018
    Date of Patent: August 30, 2022
    Assignee: Ohio University
    Inventors: John Kopchick, Vishwajeet Puri, Vishva Sharma, Reetobrata Basu
  • Publication number: 20200222502
    Abstract: FSP27 compositions and methods for treating cancers are described.
    Type: Application
    Filed: September 17, 2018
    Publication date: July 16, 2020
    Applicant: Ohio University
    Inventors: John Kopchick, Vishwajeet Puri, Vishva Sharma, Reetobrata Basu
  • Publication number: 20200179483
    Abstract: Methods and FSP27 compositions for treating and/or preventing metabolic disease and conditions associated insulin resistance, obesity, inflammation and dyslipidemia are described.
    Type: Application
    Filed: June 14, 2018
    Publication date: June 11, 2020
    Applicant: Ohio University
    Inventors: Vishwajeet Puri, John Kopchick, Vishva Sharma
  • Patent number: 8962811
    Abstract: Methods of increasing the yield in plant expression of recombinant proteins comprising engineering glycosylation sites into cloned genes or cDNAs for proteins using codons that drive post-translational modifications in plants; and engineering the cloned genes or cDNAs to contain a plant secretory signal sequence that targets the gene products (protein) for secretion. The methods result in increased recombinant glycosylated protein yields. Proteins produced according to these methods are disclosed.
    Type: Grant
    Filed: April 3, 2013
    Date of Patent: February 24, 2015
    Assignee: Ohio University
    Inventors: Marcia J. Kieliszewski, Jianfeng Xu, John Kopchick, Shigeru Okada, Gary Meyer
  • Publication number: 20140024806
    Abstract: Methods of increasing the yield in plant expression of recombinant proteins comprising engineering glycosylation sites into cloned genes or cDNAs for proteins using codons that drive post-translational modifications in plants; and engineering the cloned genes or cDNAs to contain a plant secretory signal sequence that targets the gene products (protein) for secretion. The methods result in increased recombinant glycosylated protein yields. Proteins produced according to these methods are disclosed.
    Type: Application
    Filed: April 3, 2013
    Publication date: January 23, 2014
    Applicant: Ohio University
    Inventors: Marcia J. Kieliszewski, Jianfeng Xu, John Kopchick, Shigeru Okada, Gary Meyer
  • Publication number: 20110230404
    Abstract: Methods of increasing the yield in plant expression of recombinant proteins comprising engineering glycosylation sites into cloned genes or cDNAs for proteins using codons that drive post-translational modifications in plants; and engineering the cloned genes or cDNAs to contain a plant secretory signal sequence that targets the gene products (protein) for secretion. The methods result in increased recombinant glycosylated protein yields. Proteins produced according to these methods are disclosed.
    Type: Application
    Filed: January 13, 2011
    Publication date: September 22, 2011
    Applicant: OHIO UNIVERSITY
    Inventors: Marcia J. Kieliszewski, Jianfeng Xu, John Kopchick, Shigeru Okada, Gary D. Meyer
  • Publication number: 20100029548
    Abstract: Methods of increasing the yield in plant expression of recombinant proteins comprising: engineering glycosylation sites into cloned genes or cDNAs for proteins using codons that drive post-translational modifications in plants; and engineering the cloned genes or cDNAs to contain a plant secretory signal sequence that targets the gene products (protein) for secretion. The methods result in increased recombinant glycosylated protein yields. Proteins produced according to these methods are disclosed.
    Type: Application
    Filed: May 8, 2008
    Publication date: February 4, 2010
    Applicant: Ohio University
    Inventors: Marcia J. Kieliszewski, Jianfeng Xu, John Kopchick, Shigeru Okada, Gary D. Meyer
  • Publication number: 20070142311
    Abstract: Mouse genes differentially expressed in comparisons of normal vs. hyperinsulinemic, hyperinsulinemic vs. type 2 diabetic, and normal vs. type 2 diabetic liver by gene chip analysis have been identified, as have corresponding human genes and proteins. The human molecules, or antagonists thereof, may be used for protection against hyperinsulinemia or type 2 diabetes, or their sequelae.
    Type: Application
    Filed: April 2, 2004
    Publication date: June 21, 2007
    Inventors: John Kopchick, Bruce Kedler, Keith Boyce, Andres Kriete
  • Publication number: 20070111933
    Abstract: Mouse genes differentially expressed in comparisons of older and younger livers by gene chip analysis have been identified, as have corresponding human genes and proteins. The human molecules, or antagonists thereof, may be used for protection against faster-than-normal biological aging, or to achieve slower-than-normal biological aging. The human molecules may also be used as markers of biological aging.
    Type: Application
    Filed: June 2, 2004
    Publication date: May 17, 2007
    Inventors: John Kopchick, Bruce Kelder, Keith Boyce, Andres Kriete
  • Publication number: 20060240500
    Abstract: Various nucleic acids and proteins have been identified by differential hybridization methods as useful as markers for diagnosing kidney damage. The identified marker proteins include (I) androgen related protein, SON protein, FUSE binding Protein 1, claudin10, heat shock protein, phospho triesterase related protein, ubiquitin protein ligase Nedd-4, and Ac39/physophilin, and (II) disabled-2 p96, palmitylated serine/threonine kinase, tumor differentially expressed 1 protein, cytochrome oxidase III, TLH 39 protein precursor, hydroxysteroid dehydrogenase 4 delta <5>-3 beta, and glutathione peroxidase III. The proteins of group (I), and antagonists of the proteins of group (II), are useful for protecting mammals against kidney damage.
    Type: Application
    Filed: August 4, 2003
    Publication date: October 26, 2006
    Applicant: Ohio University
    Inventors: John Kopchick, Karen Coschigano, Amy Wetzel
  • Publication number: 20060148680
    Abstract: Methods of increasing the yield in plant expression of recombinant proteins comprising: engineering glycosylation sites into cloned genes or cDNAs for proteins using codons that drive post-translational modifications in plants; and engineering the cloned genes or cDNAs to contain a plant secretory signal sequence that targets the gene products (protein) for secretion. The methods result in increased recombinant glycosylated protein yields. Proteins produced according to these methods are disclosed.
    Type: Application
    Filed: January 14, 2005
    Publication date: July 6, 2006
    Inventors: Marcia Kieliszewski, Jianfeng Xu, John Kopchick, Shigeru Okada
  • Publication number: 20050203018
    Abstract: Growth homone-regulatable liver genes and proteins are described. These may be used as diagnostic markers of liver pathology.
    Type: Application
    Filed: January 11, 2005
    Publication date: September 15, 2005
    Inventors: John Kopchick, Jean Tiong