Abstract: Methods of improving motor function in subjects diagnosed with a central nervous system injury are contemplated as including an administration of a psychedelic, empathogenic, or dissociative compound in a pharmaceutically effective amount followed by administration of a motor skill restoration therapy. The psychedelic, empathogenic, or dissociative compound may be administered to a subject that has been determined to be therapy refractive with a chronic central nervous system injury, to a subject with a subacute central nervous system injury sustained within 7 days and 6 months prior, or to a subject with an acute central nervous system injury sustained within the past 7 days. Such methods may be seen improve motor function in the subjects.

Abstract: Provided is a rehabilitation and training gaming system that can comprise a mechanism of detecting user inputs, such as a camera, joystick, force sensor, position sensor, inertial sensor, robotic interface, bioelectrical signal sensor, etc., computing unit(s) for processing inputs and generating outputs, and a computer-rendered object that is at least partially controlled by the user's inputs in a physics-driven manner. The physics-driven manner involves the computer-rendered object responding to user inputs in a manner which is both continuous and time-dependent, including but not limited to: a viscosity relationship, where the velocity, or rate of change, of a property of the computer-rendered object is proportional to the user's input, or an inertial relationship, where the acceleration, or second time derivative, of a property of the computer-rendered object is proportional to the user's input.

Abstract: Provided is a system for hand rehabilitation comprising an enclosure comprising a top surface and a bottom surface opposite the top surface; a wrist support attached to the top surface and configured to support and rigidly hold a wrist in position with respect to the top surface; a finger retention support arranged on the top surface, sized to accommodate at least a fingertip, and arranged to allow the finger to exert forces on the finger retention support in any direction; a sensor housed within the enclosure and in communication with the finger retention support, the sensor configured to detect and convert forces exerted by the finger on the finger retention support in multiple degrees of freedom into an electrical signal; and a processor in electrical communication with the sensor and configured to receive the electrical signal and provide feedback to a user.

Abstract: Provided is a rehabilitation and training gaming system that can comprise a mechanism of detecting user inputs, such as a camera, joystick, force sensor, position sensor, inertial sensor, robotic interface, bioelectrical signal sensor, etc., computing unit(s) for processing inputs and generating outputs, and a computer-rendered object that is at least partially controlled by the user's inputs in a physics-driven manner. The physics-driven manner involves the computer-rendered object responding to user inputs in a manner which is both continuous and time-dependent, including but not limited to: a viscosity relationship, where the velocity, or rate of change, of a property of the computer-rendered object is proportional to the user's input, or an inertial relationship, where the acceleration, or second time derivative, of a property of the computer-rendered object is proportional to the user's input.