Abstract: A clamshell half of a split ring mechanical seal face assembly comprises a split seal ring half having circumferential and proximal surfaces that are seated against corresponding radial and axial support surfaces of a holder half. At least one extending member extends from a hole in the proximal surface to an arcuate slot in the axial support surface, or vice-versa, and thereby radially constrains the split seal ring half to remain unitized with the holder half during clamshell assembly, while permitting rotation of the split seal ring half about a shaft axis over a limited range, which in embodiments is between 2 degrees and 20 degrees. Embodiments further include a secondary seal between the holder half and split seal ring half that frictionally resists displacement of the split seal ring half.

Abstract: A clamshell half of a split ring mechanical seal face assembly comprises a split seal ring half having circumferential and proximal surfaces that are seated against corresponding radial and axial support surfaces of a holder half. At least one extending member extends from a hole in the proximal surface to an arcuate slot in the axial support surface, or vice-versa, and thereby radially constrains the split seal ring half to remain unitized with the holder half during clamshell assembly, while permitting rotation of the split seal ring half about a shaft axis over a limited range, which in embodiments is between 2 degrees and 20 degrees. Embodiments further include a secondary seal between the holder half and split seal ring half that frictionally resists displacement of the split seal ring half.

Abstract: Ceramic honeycomb extrusion apparatus and a method of extruding a honeycomb body are disclosed. The honeycomb extrusion apparatus and method utilize a homogenizer plate comprising through holes and a screen support plate comprising screen support plate openings and aligned with the through holes.

Abstract: A honeycomb ceramic substrate, a method of making thereof, and a honeycomb extrusion die configured to extrude a honeycomb ceramic substrate from a batch of ceramic or ceramic-forming material is provided. The substrate may include a lattice of intersecting walls defining a honeycomb network of flow channels extending between an inlet end and an outlet end of the honeycomb substrate. Each flow channel may be defined by a plurality of channel walls of the intersecting walls with at least two of the plurality of channel walls including concave inner surfaces facing a center of the corresponding flow channel from central portions of the concave inner surfaces to concave corner portions facing the center of the corresponding flow channel.

Abstract: A honeycomb ceramic substrate, a method of making thereof, and a honeycomb extrusion die configured to extrude a honeycomb ceramic substrate from a batch of ceramic or ceramic-forming material is provided. The substrate may include a lattice of intersecting walls defining a honeycomb network of flow channels extending between an inlet end and an outlet end of the honeycomb substrate. Each flow channel may be defined by a plurality of channel walls of the intersecting walls with at least two of the plurality of channel walls including concave inner surfaces facing a center of the corresponding flow channel from central portions of the concave inner surfaces to concave corner portions facing the center of the corresponding flow channel.

Abstract: A method of making a die body configured to extrude a honeycomb body, the method comprising the step (I) of manufacturing a die body and the step (II) of predetermining an upstream slot width W1 of the die body such that the upstream slot width W1 is optimized while a root of each die pin includes a section modulus within a predetermined section modulus range. The method still further comprises the step (III) of predetermining a slot length L such that a pin stress is within a predetermined pin stress range.

Abstract: A honeycomb ceramic substrate, a method of making thereof, and a honeycomb extrusion die configured to extrude a honeycomb ceramic substrate from a batch of ceramic or ceramic-forming material is provided. The substrate may include a lattice of intersecting walls defining a honeycomb network of flow channels extending between an inlet end and an outlet end of the honeycomb substrate. Each flow channel may be defined by a plurality of channel walls of the intersecting walls with at least two of the plurality of channel walls including concave inner surfaces facing a center of the corresponding flow channel from central portions of the concave inner surfaces to concave corner portions facing the center of the corresponding flow channel.

Abstract: A method of making a die body configured to extrude a honeycomb body, the method comprising the step (I) of manufacturing a die body and the step (II) of predetermining an upstream slot width W1 of the die body such that the upstream slot width W1 is optimized while a root of each die pin includes a section modulus within a predetermined section modulus range. The method still further comprises the step (III) of predetermining a slot length L such that a pin stress is within a predetermined pin stress range.

Abstract: A stent is provided with a drug-eluting layer disposed on at least a portion of its surface, wherein the drug-eluting layer comprises an endosome-disrupting agent and a pharmaceutical agent. In an embodiment, the endosome-disrupting agent, when taken up through endocytosis into living cells, causes lysis of endosomes containing the endosome-disrupting agent. The pharmaceutical agent can accompany the endosome-disrupting agent into the living cells.

Abstract: A drug-eluting endoprosthesis that includes a bioerodible metal portion and a therapeutic agent. In some aspects, the endoprosthesis includes a plurality of discrete deposits and a plurality of overlying layers each overlying one of the plurality of discrete deposits. Each discrete deposit includes one or more therapeutic agents and each overlying layer includes one or more bioerodible metals. In other aspects, the bioerodible metal portion includes at least two bioerodible metal regions having different electronegativities. The at least two bioerodible metal regions being in electrical contact with each other. The bioerodible metal erodes in a physiological environment to release the therapeutic agent.

Abstract: A stent is provided with a drug-eluting layer disposed on at least a portion of its surface, wherein the drug-eluting layer comprises an endosome-disrupting agent and a pharmaceutical agent. In an embodiment, the endosome-disrupting agent, when taken up through endocytosis into living cells, causes lysis of endosomes containing the endosome-disrupting agent. The pharmaceutical agent can accompany the endosome-disrupting agent into the living cells.

Abstract: Disclosed are methods to prepare a specimen for microanalysis, the specimens so prepared, and methods to analyze the specimens by atom probe microscopy. The specimens are prepared by embedding a specimen within an electrically conductive matrix to yield an embedded specimen; and then forming regions on the embedded specimen into shapes suitable for microanalysis by an atom probe.

Abstract: A bi-directional overrunning clutch assembly employed in connection with a reduced capacity low friction clutch to provide low and reverse gears in a transmission. The clutch assembly including an inner race, an outer race, and engagement members supported therebetween. The inner race is operatively coupled to the transmission casing and the outer race is operatively coupled to the ring gear of the gear set as well as the inner race of the friction clutch assembly. The clutch assembly further includes at least one actuating cam. The actuating cam operates to actuate the engagement members to provide four separate modes of operation between the inner and outer races of the clutch assembly.