Patents by Inventor John Kummailil
John Kummailil has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240139097Abstract: The present disclosure relates to injectable compositions sterile injectable fluid compositions comprising a polysaccharide having a color in the visible spectrum, methods of forming the same, kits containing the same, and methods for performing agent-assisted procedures in a patient using the same.Type: ApplicationFiled: January 5, 2024Publication date: May 2, 2024Applicant: Boston Scientific Scimed, Inc.Inventors: Joseph T. Delaney, JR., Samuel Raybin, John Kummailil, Matthew B. Hollyer
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Publication number: 20240117121Abstract: In some aspects, the present disclosure pertains to multi-arm polymers that comprise a core and a plurality of polymer segments having a first end that is covalently attached to the core and (a) a second end comprising a moiety that comprises a reactive end group, wherein the polymer segments comprise one or more hydrophilic aprotic NMP-polymerizable monomers, and wherein the reactive multi-arm polymer comprises nitroxide radicals or (b) a second end comprising a moiety that comprises an alkoxyamine group, wherein the core is a polyol residue, and wherein the polymer segments comprise one or more NMP-polymerizable monomers. In some aspects, the present disclosure pertains to a multifunctional alkoxyamine molecule comprising a core and a plurality of alkoxyamine groups covalently attached to the core, wherein the core is a polyol residue.Type: ApplicationFiled: October 18, 2023Publication date: April 11, 2024Applicant: Boston Scientific Scimed, Inc.Inventors: Joseph T. Delaney, JR., Paul V. Grosso, John Kummailil, Tatyana Dyndikova, Carey Rehder
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Patent number: 11938216Abstract: The present disclosure relates to injectable compositions sterile injectable fluid compositions comprising a polysaccharide having a color in the visible spectrum, methods of forming the same, kits containing the same, and methods for performing agent-assisted procedures in a patient using the same.Type: GrantFiled: July 20, 2017Date of Patent: March 26, 2024Assignee: Boston Scientific Scimed, Inc.Inventors: Joseph T. Delaney, Jr., Samuel Raybin, John Kummailil, Matthew B. Hollyer
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Publication number: 20240026081Abstract: In some aspects, the present disclosure pertains to a multi-arm polymer comprising a core and a plurality of polyoxazoline segments (or arms) having a first end that is covalently attached to the core and a second end comprising a moiety that comprises a reactive group. In some aspects, systems are provided that comprise a first composition comprising such a multi-arm polymer and a second composition comprising a multifunctional compound that comprises functional groups that are reactive with the reactive groups of the multi-arm polymer. In some aspects, systems are provided that comprise crosslinked reaction products of such a multi-arm polymer and such a multifunctional compound.Type: ApplicationFiled: September 27, 2023Publication date: January 25, 2024Applicant: Boston Scientific Scimed Inc.Inventors: Joseph T. Delaney, JR., Paul V. Grosso, John Kummailil, Tatyana Dyndikova, Carey Rehder
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Patent number: 11820868Abstract: In some aspects, the present disclosure pertains to multi-arm polymers that comprise a core and a plurality of polymer segments having a first end that is covalently attached to the core and (a) a second end comprising a moiety that comprises a reactive end group, wherein the polymer segments comprise one or more hydrophilic aprotic NMP-polymerizable monomers, and wherein the reactive multi-arm polymer comprises nitroxide radicals or (b) a second end comprising a moiety that comprises an alkoxyamine group, wherein the core is a polyol residue, and wherein the polymer segments comprise one or more NMP-polymerizable monomers. In some aspects, the present disclosure pertains to a multifunctional alkoxyamine molecule comprising a core and a plurality of alkoxyamine groups covalently attached to the core, wherein the core is a polyol residue.Type: GrantFiled: August 21, 2020Date of Patent: November 21, 2023Assignee: Boston Scientific Scimed, Inc.Inventors: Joseph T. Delaney, Jr., Paul V. Grosso, John Kummailil, Tatyana Dyndikova, Carey Rehder
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Patent number: 11807720Abstract: In some aspects, the present disclosure pertains to a multi-arm polymer comprising a core and a plurality of polyoxazoline segments (or arms) having a first end that is covalently attached to the core and a second end comprising a moiety that comprises a reactive group. In some aspects, systems are provided that comprise a first composition comprising such a multi-arm polymer and a second composition comprising a multifunctional compound that comprises functional groups that are reactive with the reactive groups of the multi-arm polymer. In some aspects, systems are provided that comprise crosslinked reaction products of such a multi-arm polymer and such a multifunctional compound.Type: GrantFiled: August 21, 2020Date of Patent: November 7, 2023Assignee: Boston Scientific Scimed, Inc.Inventors: Joseph T. Delaney, Jr., Paul V. Grosso, John Kummailil, Tatyana Dyndikova, Carey Rehder
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Publication number: 20230149974Abstract: Methods of treating a substrate, e.g., forming a coating on the substrate, are described. The method may include applying a solution comprising a multifunctional molecule or a multifunctional-polymer molecule to at least a portion of a surface of the substrate. The surface may comprise a metal or metal alloy and the multifunctional molecule or a multifunctional-polymer molecule may bond to the surface via at least one sulfur group of a plurality of sulfur groups of the multifunctional molecule. The method may include combining the multifunctional molecule with a polymer molecule to form the multifunctional polymer molecule before or after applying the solution. The polymer molecule may bond to an internal carbon group or a terminal sulfur group of the multifunctional molecule.Type: ApplicationFiled: November 10, 2022Publication date: May 18, 2023Applicant: Boston Scientific Scimed, Inc.Inventors: Joseph T. DELANEY, JR., John KUMMAILIL, Paul V. GROSSO, Yen-Hao HSU
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Publication number: 20220243009Abstract: In some aspects, the present disclosure pertains to multi-arm polymers that comprise a core, a plurality of polymer segments having a first end that is covalently attached to the core and a second end comprising a moiety that comprises a reactive group, wherein the polymer segments comprise one or more free-radical-polymerizable monomers. In some aspects, systems are provided that comprise a first composition comprising such a multi-arm polymer and a second composition comprising a multifunctional compound that comprises functional groups that are reactive with the reactive groups of the multi-arm polymer. In some aspects, systems are provided that comprise crosslinked reaction products of such a multi-arm polymer and such a multifunctional compound.Type: ApplicationFiled: April 20, 2022Publication date: August 4, 2022Applicant: Boston Scientific Scimed Inc.Inventors: Joseph Thomas Delaney, JR., Carey Rehder, Tatyana Dyndikova, John Kummailil
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Patent number: 11326022Abstract: In some aspects, the present disclosure pertains to multi-arm polymers that comprise a core, a plurality of polymer segments having a first end that is covalently attached to the core and a second end comprising a moiety that comprises a reactive group, wherein the polymer segments comprise one or more free-radical-polymerizable monomers. In some aspects, systems are provided that comprise a first composition comprising such a multi-arm polymer and a second composition comprising a multifunctional compound that comprises functional groups that are reactive with the reactive groups of the multi-arm polymer. In some aspects, systems are provided that comprise crosslinked reaction products of such a multi-arm polymer and such a multifunctional compound.Type: GrantFiled: August 21, 2020Date of Patent: May 10, 2022Assignee: BOSTON SCIENTIFIC SCIMED, INC.Inventors: Joseph T. Delaney, Jr., Carey Rehder, Tatyana Dyndikova, John Kummailil
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Publication number: 20220096141Abstract: A method of forming an energy delivery portion of a medical device includes contacting a distal portion of an electrode shaft with an insulating material, and heating the insulating material to couple the insulating material to the distal portion of the electrode shaft to form an insulation tip. The distal portion of the electrode shaft includes one or more surface contours to entrain the insulating material.Type: ApplicationFiled: September 17, 2021Publication date: March 31, 2022Applicant: Boston Scientific Scimed, Inc.Inventors: John KUMMAILIL, Matthew P. JONES, Sverre GROPEN
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Publication number: 20210386472Abstract: A medical device includes an electrode shaft and a tip. The electrode shaft is configured to deliver energy to a target site and includes an electrode shaft lumen configured to deliver fluid to the target site. The tip is coupled to a distal tip of the electrode shaft. The tip includes an inner portion of conductive material and an exterior layer of insulative material. The tip includes a tip lumen fluidly connected to the electrode shaft lumen and configured to deliver fluid to the target site.Type: ApplicationFiled: June 4, 2021Publication date: December 16, 2021Applicant: Boston Scientific Scimed Inc.Inventors: Daniel J. FOSTER, Matthew P. Jones, Allyn N. Jensrud, John Kummailil
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Publication number: 20210061950Abstract: In some aspects, the present disclosure pertains to multi-arm polymers that comprise a core, a plurality of polymer segments having a first end that is covalently attached to the core and a second end comprising a moiety that comprises a reactive group, wherein the polymer segments comprise one or more free-radical-polymerizable monomers. In some aspects, systems are provided that comprise a first composition comprising such a multi-arm polymer and a second composition comprising a multifunctional compound that comprises functional groups that are reactive with the reactive groups of the multi-arm polymer. In some aspects, systems are provided that comprise crosslinked reaction products of such a multi-arm polymer and such a multifunctional compound.Type: ApplicationFiled: August 21, 2020Publication date: March 4, 2021Inventors: Joseph T. Delaney, Jr., Carey Rehder, Tatyana Dyndikova, John Kummailil
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Publication number: 20210061954Abstract: In some aspects, the present disclosure pertains to a multi-arm polymer comprising a core and a plurality of polyoxazoline segments (or arms) having a first end that is covalently attached to the core and a second end comprising a moiety that comprises a reactive group. In some aspects, systems are provided that comprise a first composition comprising such a multi-arm polymer and a second composition comprising a multifunctional compound that comprises functional groups that are reactive with the reactive groups of the multi-arm polymer. In some aspects, systems are provided that comprise crosslinked reaction products of such a multi-arm polymer and such a multifunctional compound.Type: ApplicationFiled: August 21, 2020Publication date: March 4, 2021Inventors: Joseph T. Delaney, Jr., Paul V. Grosso, John Kummailil, Tatyana Dyndikova, Carey Rehder
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Publication number: 20210061957Abstract: In some aspects, the present disclosure pertains to multi-arm polymers that comprise a core and a plurality of polymer segments having a first end that is covalently attached to the core and (a) a second end comprising a moiety that comprises a reactive end group, wherein the polymer segments comprise one or more hydrophilic aprotic NMP-polymerizable monomers, and wherein the reactive multi-arm polymer comprises nitroxide radicals or (b) a second end comprising a moiety that comprises an alkoxyamine group, wherein the core is a polyol residue, and wherein the polymer segments comprise one or more NMP-polymerizable monomers. In some aspects, the present disclosure pertains to a multifunctional alkoxyamine molecule comprising a core and a plurality of alkoxyamine groups covalently attached to the core, wherein the core is a polyol residue.Type: ApplicationFiled: August 21, 2020Publication date: March 4, 2021Inventors: Joseph T. Delaney, JR., Paul V. Grosso, John Kummailil, Tatyana Dyndikova, Carey Rehder
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Patent number: 10517999Abstract: A medical device for insertion or implantation in a body includes a polymer substrate and a layer of poly(vinyl pyrrolidone-alt-maleic anhydride) formed on a surface of the polymer substrate. Polymer chains of the poly(vinyl pyrrolidone-alt-maleic anhydride) are entangled with the polymer substrate.Type: GrantFiled: April 12, 2017Date of Patent: December 31, 2019Assignee: Cardiac Pacemakers, Inc.Inventors: John Kummailil, Paul V. Grosso, Joseph T. Delaney, Jr.
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Patent number: 9992489Abstract: A method of calibrating an image sensor may include detecting a response from a pixel of the image sensor as a result of light having an intensity impinging on the pixel, and measuring the actual standard deviation of the response of the pixel at the intensity of light. The method may also include determining an averaging number for the pixel at the intensity. The averaging number may be a number of responses of the pixel at the intensity to be averaged to attain an average response having a standard deviation less than or equal to a target value. The method may further include determining the average response of the pixel using the determined averaging number.Type: GrantFiled: December 5, 2016Date of Patent: June 5, 2018Assignee: Boston Scientific Scimed, Inc.Inventors: John Kummailil, Nathaniel McCaffrey
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Publication number: 20180021252Abstract: The present disclosure relates to injectable compositions sterile injectable fluid compositions comprising a polysaccharide having a color in the visible spectrum, methods of forming the same, kits containing the same, and methods for performing agent-assisted procedures in a patient using the same.Type: ApplicationFiled: July 20, 2017Publication date: January 25, 2018Inventors: Joseph T. Delaney, Samuel Raybin, John Kummailil, Matthew B. Hollyer
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Publication number: 20170290955Abstract: A medical device for insertion or implantation in a body includes a polymer substrate and a layer of poly(vinyl pyrrolidone-alt-maleic anhydride) formed on a surface of the polymer substrate. Polymer chains of the poly(vinyl pyrrolidone-alt-maleic anhydride) are entangled with the polymer substrate.Type: ApplicationFiled: April 12, 2017Publication date: October 12, 2017Inventors: John Kummailil, Paul V. Grosso, Joseph T. Delaney, JR.
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Publication number: 20170085870Abstract: A method of calibrating an image sensor may include detecting a response from a pixel of the image sensor as a result of light having an intensity impinging on the pixel, and measuring the actual standard deviation of the response of the pixel at the intensity of light. The method may also include determining an averaging number for the pixel at the intensity. The averaging number may be a number of responses of the pixel at the intensity to be averaged to attain an average response having a standard deviation less than or equal to a target value. The method may further include determining the average response of the pixel using the determined averaging number.Type: ApplicationFiled: December 5, 2016Publication date: March 23, 2017Applicant: Boston Scientific Scimed, Inc.Inventors: John Kummailil, Nathaniel McCaffrey
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Patent number: 9565994Abstract: An articulating portion for an elongate medical device is disclosed. The articulating portion may include a plurality of segments movable relative to one another, and a plurality of hinges disposed between adjacent segments. The segments can be configured to bend at the hinges upon manipulation of a control member of the device. The segments and the hinges can also be a single continuous piece of material.Type: GrantFiled: October 28, 2015Date of Patent: February 14, 2017Assignee: Boston Scientific Scimed, Inc.Inventors: Gary S. Kappel, Francis T. MacNamara, Federico Gutierrez, John Kummailil, Thomas M. Ragonese, Robert B. DeVries, Paul Smith