Patents by Inventor John L. Gainer

John L. Gainer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ORAL FORMULATIONS OF BIPOLAR TRANS CAROTENOIDS
    Publication number: 20230346733
    Abstract: The subject invention relates to a variety of formulations of bipolar trans carotenoids including pharmaceutical compositions for oral delivery of a bipolar trans carotenoid comprising i) a bipolar trans carotenoid, ii) a cyclodextrin, and iii) a coating. The invention also relates to preparation of such formulations and their uses.
    Type: Application
    Filed: November 7, 2022
    Publication date: November 2, 2023
    Inventors: John L. Gainer, Robert Murray
  • TRANS CAROTENOIDS, THEIR SYNTHESIS, FORMULATION AND USES
    Publication number: 20220387589
    Abstract: The invention relates to trans carotenoid compounds and salts thereof as well as compositions thereof, methods for making them, and uses thereof. These compounds are useful in improving diffusivity of oxygen between red blood cells and body tissues in mammals including humans.
    Type: Application
    Filed: January 31, 2022
    Publication date: December 8, 2022
    Inventors: John L. Gainer, Marc Lanz
  • Oral formulations of bipolar trans carotenoids
    Patent number: 11491129
    Abstract: The subject invention relates to a variety of formulations of bipolar trans carotenoids including pharmaceutical compositions for oral delivery of a bipolar trans carotenoid comprising i) a bipolar trans carotenoid, ii) a cyclodextrin, and iii) a coating. The invention also relates to preparation of such formulations and their uses.
    Type: Grant
    Filed: July 9, 2018
    Date of Patent: November 8, 2022
    Assignee: DIFFUSION PHARMACEUTICALS LLC
    Inventors: John L. Gainer, Robert Murray
  • USE OF BIPOLAR TRANS CAROTENOIDS WITH CHEMOTHERAPY AND RADIOTHERAPY FOR TREATMENT OF CANCER
    Publication number: 20220265592
    Abstract: The subject disclosure relates to compounds and compositions including chemotherapy agents and/or radiation therapy with bipolar trans carotenoids, and the use of such compounds for the treatment of various cancers including pancreatic and brain cancers.
    Type: Application
    Filed: October 31, 2021
    Publication date: August 25, 2022
    Inventor: John L. GAINER
  • DIFFUSION ENHANCING COMPOUNDS AND THEIR USE ALONE OR WITH THROMBOLYTICS
    Publication number: 20220241385
    Abstract: The subject invention relates to diffusion enhancing compounds and their use alone or with thrombolytic agents for the treatment of disorders resulting from the formation of a thrombus such as a myocardial infarction or stroke.
    Type: Application
    Filed: October 11, 2021
    Publication date: August 4, 2022
    Inventor: John L. Gainer
  • Trans carotenoids, their synthesis, formulation and uses
    Patent number: 11278621
    Abstract: The invention relates to trans carotenoid compounds and salts thereof as well as compositions thereof, methods for making them, and uses thereof. These compounds are useful in improving diffusivity of oxygen between red blood cells and body tissues in mammals including humans.
    Type: Grant
    Filed: March 20, 2018
    Date of Patent: March 22, 2022
    Assignee: DIFFUSION PHARMACEUTICALS LLC
    Inventors: John L. Gainer, Marc Lanz
  • Use of bipolar trans carotenoids with chemotherapy and radiotherapy for treatment of cancer
    Patent number: 11185523
    Abstract: The subject disclosure relates to compounds and compositions including chemotherapy agents and/or radiation therapy with bipolar trans carotenoids, and the use of such compounds for the treatment of various cancers including pancreatic and brain cancers.
    Type: Grant
    Filed: March 23, 2017
    Date of Patent: November 30, 2021
    Assignee: DIFFUSION PHARMACEUTICALS LLC
    Inventor: John L. Gainer
  • Diffusion enhancing compounds and their use alone or with thrombolytics
    Patent number: 11147859
    Abstract: The subject invention relates to diffusion enhancing compounds and their use alone or with thrombolytic agents for the treatment of disorders resulting from the formation of a thrombus such as a myocardial infarction or stroke.
    Type: Grant
    Filed: November 16, 2018
    Date of Patent: October 19, 2021
    Assignee: DIFFUSION PHARMACEUTICALS LLC
    Inventor: John L. Gainer
  • USE OF BIPOLAR TRANS CAROTENOIDS WITH CHEMOTHERAPY AND RADIOTHERAPY FOR TREATMENT OF CANCER
    Publication number: 20190083439
    Abstract: The subject disclosure relates to compounds and compositions including chemotherapy agents and/or radiation therapy with bipolar trans carotenoids, and the use of such compounds for the treatment of various cancers including pancreatic and brain cancers.
    Type: Application
    Filed: March 23, 2017
    Publication date: March 21, 2019
    Inventor: John L. GAINER
  • DIFFUSION ENHANCING COMPOUNDS AND THEIR USE ALONE OR WITH THROMBOLYTICS
    Publication number: 20190083584
    Abstract: The subject invention relates to diffusion enhancing compounds and their use alone or with thrombolytic agents for the treatment of disorders resulting from the formation of a thrombus such as a myocardial infarction or stroke.
    Type: Application
    Filed: November 16, 2018
    Publication date: March 21, 2019
    Applicant: DIFFUSION PHARMACEUTICALS LLC
    Inventor: John L. GAINER
  • ORAL FORMULATIONS OF BIPOLAR TRANS CAROTENOIDS
    Publication number: 20190038586
    Abstract: The subject invention relates to a variety of formulations of bipolar trans carotenoids including pharmaceutical compositions for oral delivery of a bipolar trans carotenoid comprising i) a bipolar trans carotenoid, ii) a cyclodextrin, and iii) a coating. The invention also relates to preparation of such formulations and their uses.
    Type: Application
    Filed: July 9, 2018
    Publication date: February 7, 2019
    Applicant: Diffusion Pharmaceuticals LLC
    Inventors: John L. GAINER, Robert MURRAY
  • Diffusion enhancing compounds and their use alone or with thrombolytics
    Patent number: 10130689
    Abstract: The subject invention relates to diffusion enhancing compounds and their use alone or with thrombolytic agents for the treatment of disorders resulting from the formation of a thrombus such as a myocardial infarction or stroke.
    Type: Grant
    Filed: June 22, 2010
    Date of Patent: November 20, 2018
    Assignee: DIFFUSION PHARMACEUTICALS LLC
    Inventor: John L. Gainer
  • TRANS CAROTENOIDS, THEIR SYNTHESIS, FORMULATION AND USES
    Publication number: 20180271979
    Abstract: The invention relates to trans carotenoid compounds and salts thereof as well as compositions thereof, methods for making them, and uses thereof. These compounds are useful in improving diffusivity of oxygen between red blood cells and body tissues in mammals including humans.
    Type: Application
    Filed: March 20, 2018
    Publication date: September 27, 2018
    Applicant: Diffusion Pharmaceuticals LLC
    Inventors: John L. GAINER, Marc LANZ
  • Oral formulations of bipolar trans carotenoids
    Patent number: 10016384
    Abstract: The subject invention relates to a variety of formulations of bipolar trans carotenoids including pharmaceutical compositions for oral delivery of a bipolar trans carotenoid comprising i) a bipolar trans carotenoid, ii) a cyclodextrin, and iii) a coating. The invention also relates to preparation of such formulations and their uses.
    Type: Grant
    Filed: March 9, 2015
    Date of Patent: July 10, 2018
    Assignee: DIFFUSION PHARMACEUTICALS LLC
    Inventors: John L. Gainer, Robert Murray
  • Trans carotenoids, their synthesis, formulation and uses
    Patent number: 9950067
    Abstract: The invention relates to trans carotenoid compounds and salts thereof as well as compositions thereof, methods for making them, and uses thereof. These compounds are useful in improving diffusivity of oxygen between red blood cells and body tissues in mammals including humans.
    Type: Grant
    Filed: January 11, 2016
    Date of Patent: April 24, 2018
    Assignee: Diffusion Pharmaceuticals, LLC
    Inventors: John L. Gainer, Marc Lanz
  • BIPOLAR TRANS CARTENOID SALTS AND THEIR USES
    Publication number: 20170202798
    Abstract: The invention relates to trans carotenoid salt compounds, methods for making them, methods for solubilizing them and uses thereof. These compounds are useful in improving diffusivity of oxygen between red blood cells and body tissues in mammals including humans.
    Type: Application
    Filed: January 30, 2017
    Publication date: July 20, 2017
    Applicant: DIFFUSION PHARMACEUTICALS LLC
    Inventors: John L. GAINER, Raymond C. GRABIAK
  • Bipolar trans carotenoid salts and their uses
    Patent number: 9604899
    Abstract: The invention relates to trans carotenoid salt compounds, methods for making them, methods for solubilizing them and uses thereof. These compounds are useful in improving diffusivity of oxygen between red blood cells and body tissues in mammals including humans.
    Type: Grant
    Filed: August 8, 2011
    Date of Patent: March 28, 2017
    Assignee: Diffusion Pharmaceuticals LLC
    Inventors: John L. Gainer, Raymond C. Grabiak
  • TRANS CAROTENOIDS, THEIR SYNTHESIS, FORMULATION AND USES
    Publication number: 20160199490
    Abstract: The invention relates to trans carotenoid compounds and salts thereof as well as compositions thereof, methods for making them, and uses thereof. These compounds are useful in improving diffusivity of oxygen between red blood cells and body tissues in mammals including humans.
    Type: Application
    Filed: January 11, 2016
    Publication date: July 14, 2016
    Inventors: John L. Gainer, Marc Lanz
  • ORAL FORMULATIONS OF BIPOLAR TRANS CAROTENOIDS
    Publication number: 20150352068
    Abstract: The subject invention relates to a variety of formulations of bipolar trans carotenoids including pharmaceutical compositions for oral delivery of a bipolar trans carotenoid comprising i) a bipolar trans carotenoid, ii) a cyclodextrin, and iii) a coating. The invention also relates to preparation of such formulations and their uses.
    Type: Application
    Filed: March 9, 2015
    Publication date: December 10, 2015
    Inventors: John L. Gainer, Robert MURRAY
  • Oral formulations of bipolar trans carotenoids
    Patent number: 8974822
    Abstract: The subject invention relates to a variety of formulations of bipolar trans carotenoids including pharmaceutical compositions for oral delivery of a bipolar trans carotenoid comprising i) a bipolar trans carotenoid, ii) a cyclodextrin, and iii) a coating. The invention also relates to preparation of such formulations and their uses.
    Type: Grant
    Filed: June 2, 2011
    Date of Patent: March 10, 2015
    Assignee: Diffusion Pharmaceuticals LLC
    Inventors: John L. Gainer, Robert Murray