Abstract: The present invention is directed to cinnolinyl and quinolinyl pyrazol-4-yl-pyridine compounds which are allosteric modulators of the M4 muscarinic acetylcholine receptor. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which M4 muscarinic acetylcholine receptors are involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the potential prevention or treatment of such diseases in which M4 muscarinic acetylcholine receptors are involved.

Abstract: An optical pattern tracer is disclosed, of the circular scanning type. The interception of the pattern by the scan produces electrical outputs which are reduced to numerical values representative of their time of occurrence with reference to the scanning circle. The numbers derived and the nature of the signal generated are then processed to indicate the direction of the pattern, presence or absence of command marks and combined with other reference inputs, such as kerf and direction of tracing used to control a drive mechanism to move the tracer around the pattern.