Patents by Inventor John L. Herrmann
John L. Herrmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7253266Abstract: The present invention provides FGF-CX, a novel isolated polypeptide, as well as a polynucleotide encoding FGF-CX and antibodies that immunospecifically bind to FGF-CX or any derivative, variant, mutant, or fragment of the FGF-CX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the FGF-CX polypeptide, polynucleotide and antibody are used in detection and treatment of a broad range of pathological states, as well as other uses.Type: GrantFiled: June 17, 2002Date of Patent: August 7, 2007Assignee: CuraGen CorporationInventors: Richard A. Shimkets, Michael Jeffers, Sudhirdas K. Prayaga, Ferenc L. Boldog, Meijia Yang, Catherine Burgess, Elma Fernandes, John L. Herrmann, William J. LaRochelle, Henri Lichenstein, Linda Gorman, Mei Zhong, Muralidhara Padigaru, Carol E. A. Pena, John P. Alsobrook, II, Denise M. Lepley, Daniel K. Rieger, William Grosse
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Patent number: 7056885Abstract: The present invention provides FGF-CX polypeptides and polynucleotides, and antibodies that immunospecifically bind to FGF-CX or any derivative, variant, mutant, or fragment of the FGF-CX polypeptide, polynucleotide or antibody. The invention additionally provides methods of use for the FGF-CX polypeptide, polynucleotide and antibody.Type: GrantFiled: July 3, 2000Date of Patent: June 6, 2006Assignee: CuraGen CorporationInventors: Michael Jeffers, Richard A. Shimkets, Sudhirdas K. Prayaga, Ferenc L. Boldog, Meijia Yang, Catherine Burgess, Elma Fernandes, John L. Herrmann, William J. LaRochelle, Henri Lichenstein
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Patent number: 6991901Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: GrantFiled: January 11, 2002Date of Patent: January 31, 2006Assignee: Curagen CorporationInventors: Luca Rastelli, John L. Herrmann, John R. MacDougall, Haihong Zhong
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Patent number: 6964849Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: GrantFiled: March 15, 2002Date of Patent: November 15, 2005Assignee: Curagen CorporationInventors: Luca Rastelli, John L. Herrmann, John R. MacDougall, Haihong Zhong
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Publication number: 20040214759Abstract: In methods of using a fibroblast growth factor, such as for treating, preventing or delaying a proliferation-associated disorder, steps are provided to administer to a subject a therapeutically effective amount of a particular fibroblast growth factor polypeptide, or variant or fragment thereof.Type: ApplicationFiled: May 9, 2003Publication date: October 28, 2004Inventors: John P. Alsobrook, Enrique Alvarez, David W. Anderson, Joel S. Bader, Ferenc L. Boldog, Catherine E. Burgess, Rajeev A. Chillakuru, Lisa Deegler, Shlomit R. Edinger, Elma R. Fernandes, Linda Gorman, William M. Grosse, John L. Herrmann, Michael E. Jeffers, William J. LaRochelle, Denise M. Lepley, Henri S. Lichenstein, Kumar Namdev, Muralidhara Padigaru, Carol E. A. Pena, Sudhirdas K. Prayaga, Daniel K. Rieger, Richard A. Shimkets, Pascal Valax, Meijia Yang, Zachary Yim, Mei Zhong
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Publication number: 20040058338Abstract: The present invention provides novel isolated polynucleotides and small molecule target polypeptides encoded by the polynucleotides. Antibodies that immunospecifically bind to a novel small molecule target polypeptide or any derivative, variant, mutant or fragment of that polypeptide, polynucleotide or antibody are disclosed, as are methods in which the small molecule target polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states. More specifically, the present invention discloses methods of using recombinantly expressed and/or endogenously expressed proteins in various screening procedures for the purpose of identifying therapeutic antibodies and therapeutic small molecules associated with diseases. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: December 2, 2002Publication date: March 25, 2004Inventors: Michele L. Agee, John P. Alsobrook, David W. Anderson, Constance Berghs, Ferenc L. Boldog, Catherine E. Burgess, Elina Catterton, Vincent A. DiPippo, Shlomit R. Edinger, Andrew Eisen, Karen Ellerman, Esha A. Gangolli, Valerie Gerlach, Linda Gorman, Bonnie Gould Rothberg, Xiaojia Sasha Guo, John L. Herrmann, Yuan-Di Halvorsen, Weizhen Ji, Ramesh Kekuda, Nikolai V. Khramtsov, William J. LaRochelle, Denise M. Lepley, Li Li, John R. MacDougall, Charles E. Miller, Tatiana Ort, Muralidhara Padigaru, Meera Patturajan, Carol E. A. Pena, John A. Peyman, Daniel K. Rieger, Mark E. Rothenberg, Suresh G. Shenoy, Glennda Smithson, Steven K. Spaderna, Kimberly A. Spytek, David J. Stone, Raymond J. Taupier, Corine A.M. Vernet, Edward Z. Voss, Mei Zhong
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Publication number: 20040033491Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: December 10, 2001Publication date: February 19, 2004Inventors: John P. Alsobrook, David W. Anderson, Catherine E. Burgess, Ferenc L. Boldog, Stacie J. Casman, Steven D. Colman, Shlomit R. Edinger, Karen Ellerman, Valerie Gerlach, Linda Gorman, William M. Grosse, Xiaojia Sasha Guo, John L. Herrmann, Ramesh Kekuda, Denise M. Lepley, Li Li, John R. MacDougall, Isabelle Millet, Carol E. A. Pena, John A. Peyman, Luca Rastelli, Daniel K. Rieger, Richard A. Shimkets, Glennda Smithson, Kimberly A. Spytek, David J. Stone, Velizar T. Tchernev, Corine A.M. Vernet, Edward Z. Voss, Bryan D. Zerhusen, Haihong Zhong, Mei Zhong
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Publication number: 20040018196Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: January 11, 2002Publication date: January 29, 2004Inventors: Peter D. Mezes, Luca Rastelli, John L. Herrmann, John R. MacDougall, Haihong Zhong, Stacie J. Casman, Ferenc L. Boldog, Richard A. Shimkets, Linda Gorman, Andrew J. Eisen, Steven K. Spaderna, Corine A.M. Vernet, Constance Berghs, Kimberly A. Spytek, Vincent A. DiPippo, Bryan D. Zerhusen, John A. Peyman, Karen Ellerman, David J. Stone, William M. Grosse, John P. Alsobrook, Denise M. Lepley, Daniel K. Rieger, Catherine E. Burgess, Shlomit R. Edinger
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Publication number: 20040010119Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: February 12, 2002Publication date: January 15, 2004Inventors: Xiaojia Guo, Elma Fernandes, Li Li, Ramesh Kekuda, Yi Liu, Mario Leite, Kimberly A. Spytek, Weizhen Ji, Stacie J. Casman, Ference L. Boldog, Meera Patturajan, Corine A. M. Vernet, Robert A. Ballinger, Uriel M. Malyankar, Velizar T. Tchernev, Angela D. Blalock, Vladimir Y. Gusev, Luca Rastelli, Peter D. Mezes, Karen Ellerman, Melvyn Heyes, John L. Herrmann, Richard A. Shimkets, Noelle Ioime, Carol E. A. Pena, Suresh G. Shenoy, Raymond J. Taupier, Valerie Gerlach, Linda Gorman
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Publication number: 20040005557Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: January 16, 2002Publication date: January 8, 2004Inventors: Muralidhara Padigaru, John P. Alsobrook, Steven D. Colman, Kimberly A. Spytek, Ferenc L. Boldog, Corine A.M. Vernet, Li Li, Suresh G. Shenoy, Stacie J. Casman, Xiaojia (Sasha) Guo, Shlomit R. Edinger, John R. MacDougall, Uriel M. Malyankar, Meera Patturajan, Richard A. Shimkets, Carol E. A. Pena, Velizar T. Tchernev, Bryan D. Zerhusen, Isabelle Millet, Charles E. Miller, Denise M. Lepley, Glennda Smithson, Jason C. Baumgartner, John L. Herrmann, John A. Peyman, Linda Gorman, Peter D. Mezes, Ramesh Kekuda, Raymond J. Taupier, Valerie Gerlach, William M. Grosse, Xiaohong Liu, Karen Ellerman, Mark Rothenberg, David J. Stone, Catherine E. Burgess
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Publication number: 20040002120Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: March 7, 2002Publication date: January 1, 2004Inventors: Ramesh Kekuda, Velizar T. Tchernev, Xiaohong Liu, Kimberly A. Spytek, Meera Patturajan, Catherine E. Burgess, Corine A.M. Vernet, Li Li, Linda Gorman, Uriel M. Malyankar, Ferenc L. Boldog, Xiaojia (Sasha) Guo, Suresh G. Shenoy, Muralidhara Padigaru, Raymond J. Taupier, Charles E. Miller, Stacie J. Casman, Carol E. A. Pena, Esha A. Gangolli, Vladimir Y. Gusev, Glennda Smithson, Bryan D. Zerhusen, Valerie Gerlach, Pascale F-J Pochart, Elma R. Fernandes, Richard A. Shimkets, Luca Rastelli, Steven K. Spaderna, William J. LaRochelle, Mei Zhong, Nikolai V. Khramtsov, Edward Z. Voss, John L. Herrmann
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Publication number: 20030216308Abstract: The present invention provides novel isolated NOVX polynucleotides and polypeptides encoded by the NOVX polynucleotides. Also provided are the antibodies that immunospecifically bind to a NOVX polypeptide or any derivative, variant, mutant or fragment of the NOVX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the NOVX polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states, as well as to other uses.Type: ApplicationFiled: June 17, 2002Publication date: November 20, 2003Inventors: David W. Anderson, Xiaojia (Sasha) Guo, Vladimir Y. Gusev, John L. Herrmann, Li Li, Peter S. Mezes, Muralidhara Padigaru, Meera Patturajan, Carol E. A. Pena, Luca Rastelli, Richard A. Shimkets, Glennda Smithson, Steven K. Spaderna, Raymond J. Taupier, Corine A.M. Vernet
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Publication number: 20030215449Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: March 15, 2002Publication date: November 20, 2003Inventors: Peter D. Mezes, Luca Rastelli, John L. Herrmann, John R. MacDougall, Haihong Zhong, Stacie J. Casman, Ferenc L. Boldog, Richard A. Shimkets, Linda Gorman, Andrew J. Eisen, Steven K. Spaderna, Corine A.M. Vernet, Constance Berghs, Kimberly A. Spytek, Vincent A. DiPippo, Bryan D. Zerhusen, John A. Peyman, Karen Ellerman, David J. Stone, William M. Grosse, John P. Alsobrook, Denise M. Lepley, Daniel K. Rieger, Catherine E. Burgess, Shlomit R. Edinger, Edward Z. Voss, Charles E. Miller
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Publication number: 20030204052Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: October 4, 2001Publication date: October 30, 2003Inventors: John L. Herrmann, Luca Rastelli, Richard A. Shimkets
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Publication number: 20030198958Abstract: The invention provides polypeptides, designated herein as POLYX polypeptides, as well as polynucleotides encoding POLYX polypeptides, and antibodies that immunospecifically-bind to POLYX polypeptide or polynucleotide, or derivatives, variants, mutants, or fragments thereof. The invention additionally provides methods in which the POLYX polypeptide, polynucleotide, and antibody are used in the detection, prevention, and treatment of a broad range of pathological states.Type: ApplicationFiled: March 13, 2002Publication date: October 23, 2003Inventors: Richard A. Shimkets, Elma Fernandes, John L. Herrmann, Xiaohong Liu, Meijia Yang, Ferenc L. Boldog, Glennda Smithson, Luca Rastelli
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Publication number: 20030186433Abstract: The present invention provides FGF-CX, a novel isolated polypeptide, as well as a polynucleotide encoding FGF-CX and antibodies that immunospecifically bind to FGF-CX or any derivative, variant, mutant, or fragment of the FGF-CX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the FGF-CX polypeptide, polynucleotide and antibody are used in detection and treatment of a broad range of pathological states, as well as other uses.Type: ApplicationFiled: June 17, 2002Publication date: October 2, 2003Inventors: Richard A. Shimkets, Michael Jeffers, Sudhirdas K. Prayaga, Ferenc L. Boldog, Meijia Yang, Catherine Burgess, Elma Fernandes, John L. Herrmann, William J. LaRochelle, Henri Lichenstein, Linda Gorman, Mei Zhong, Muralidhara Padigaru, Carol E. A. Pena, John P. Alsobrook, Denise M. Lepley, Daniel K. Rieger, William Grosse
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Publication number: 20030149237Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: June 27, 2001Publication date: August 7, 2003Inventors: Corine Vernet, Velizar Tchernev, Meera Patturajan, Uriel M. Malyankar, Vladimir Gusev, John L. Herrmann, John R. MacDougall, Luca Rastelli, Haihong Zhong, Kimberly A. Spytek, Suresh Shenoy, Valerie L. Gerlach, Esha A. Gangolli, David J. Stone, Glennda Smithson
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Publication number: 20030077697Abstract: The present invention provides a novel isolated SER5 polynucleotide and a polypeptide encoded by the SER5 polynucleotide. Also provided are the antibodies that immunospecifically bind to a SER5 polypeptide or any derivative, variant, mutant or fragment of the SER5 polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the SER5 polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states as well as other uses.Type: ApplicationFiled: July 3, 2001Publication date: April 24, 2003Inventors: Valerie L. Gerlach, John R. MacDougall, Kerry E. Quinn, Kumud Majumder, Kimberly A. Spytek, Corine Vernet, Catherine E. Burgess, Elma R. Fernandes, Luca Rastelli, John L. Herrmann, Steven K. Spaderna, Richard A. Shimkets, Raymond J. Taupier
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Publication number: 20030065140Abstract: Disclosed herein are novel human nucleic acid sequences which encode polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.Type: ApplicationFiled: April 3, 2001Publication date: April 3, 2003Inventors: Corine A.M. Vernet, Catherine E. Burgess, Elma R. Fernandes, Raymond J. Taupier, Kerry E. Quinn, Kimberly A. Spytek, Luca Rastelli, John L. Herrmann
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Publication number: 20030036185Abstract: This application is drawn to novel amino acid sequences for mammalian polypeptides that have sequence similarity to precursors of human kidney cadherin-6 and cadherin-10 from Gallus gallus. The novel polypeptides comprise about 473 amino acids.Type: ApplicationFiled: November 2, 2001Publication date: February 20, 2003Applicant: CuraGen CorporationInventors: Richard A. Shimkets, Elma Fernandes, Corine Vernet, Meijia Yang, Ferenc L. Boldog, John L. Herrmann