Patents by Inventor John L. Herrmann, Jr.

John L. Herrmann, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antiandrogenic sulfonylsteroidopyrazoles and processes for preparation method of use and compositions thereof
    Patent number: 4684636
    Abstract: 1'-Sulfonylsteroido[3,2-c]pyrazoles, for example, (5.alpha.,17.alpha.)-1'-(methylsulfonyl)-1'H-pregn-20-yno[3,2-c]pyrazol-17 -ol, which are useful as antiandrogenic agents, and processes for preparation, method of use and compositions thereof are disclosed.
    Type: Grant
    Filed: April 8, 1986
    Date of Patent: August 4, 1987
    Assignee: Sterling Drug Inc.
    Inventors: Robert G. Christiansen, Malcolm R. Bell, John L. Herrmann, Jr., Chester J. Opalka, Jr.
  • Pentacyclic phenylpyrazole compounds as anti-inflammatory agents
    Patent number: 4412995
    Abstract: Compounds of the formula ##STR1## where R is hydrogen, methyl, ethyl, propyl, 2-propenyl or 2-propynyl; and R' is hydrogen or fluoro possess anti-inflammatory activity. The compounds where R is H are prepared by reacting a compound of the formula ##STR2## with (1H,3H)-pyrimidine-2,4,5,6-tetrone. The compounds where R is other than hydrogen are prepared by reacting a compound where R is hydrogen with the appropriate alkylating agent.
    Type: Grant
    Filed: January 13, 1982
    Date of Patent: November 1, 1983
    Assignee: Sterling Drug Inc.
    Inventors: Malcolm R. Bell, John L. Herrmann, Jr.
  • Anti-inflammatory spiro-2H-indene-[2,3']-3H-pyrazolo[4",5":7',6']naphtho[2,1-b]pyran-1,3-d ione derivatives
    Patent number: 4349559
    Abstract: The compounds of formula ##STR1## where R is hydrogen or fluorine possess glucocorticoid activity, and are prepared by reacting a compound of the formula ##STR2## with 1,2,3-indantrione.
    Type: Grant
    Filed: February 19, 1981
    Date of Patent: September 14, 1982
    Assignee: Sterling Drug Inc.
    Inventors: Malcolm R. Bell, John L. Herrmann, Jr.
  • Dehydrohalogenation process
    Patent number: 4157349
    Abstract: 5-Ethenyl-4,4a,7,8-tetrahydro-4a-methyl-2(3H)-naphthalenone, an intermediate useful in the total synthesis of steroids, is prepared by dehydrohalogenation of 5-(2-bromoethylidene)-2(3H)-4a-methyl-4,4a,5,6,7,8-hexahydronaphthalen-2-o ne by a pyrolytic procedure or by means of dehydrohalogenating agents, for example, a mixture of lithium bromide and lithium carbonate.
    Type: Grant
    Filed: March 13, 1978
    Date of Patent: June 5, 1979
    Assignee: Sterling Drug Inc.
    Inventors: Malcolm R. Bell, John L. Herrmann, Jr., Vahan Akullian