Patents by Inventor John L. Lim

John L. Lim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Preparation and Use of Alkylating Agents
    Publication number: 20110028725
    Abstract: The present disclosure provides methods of synthesizing alkylating agents and methods of use.
    Type: Application
    Filed: August 17, 2010
    Publication date: February 3, 2011
    Applicant: The Queen's Medical Center
    Inventor: John L. Lim
  • Preparation and use of alkylating agents
    Patent number: 7776309
    Abstract: Methods of alkylating target compounds are disclosed. The alkylating agent can be radiolabelled. In some instances, the alkylating agent is synthesized and then reacted with a target compound without an intervening purification step. The method comprises a) synthesizing an alkylating agent having the formula: X—(CR1R2)aCR3R4-LG wherein, a is 0, 1, 2 or 3, R1, R2, R3 and R4 are independently H, X or alkyl, X is a halogen or a label, with the proviso that at least one X is a halogen, LG is a leaving group; and b) directly reacting said alkylating agent with a target compound comprising an alkylation reactive group under conditions suitable for the alkylation of said target compound.
    Type: Grant
    Filed: July 26, 2004
    Date of Patent: August 17, 2010
    Assignee: The Queen's Medical Center
    Inventor: John L. Lim
  • Preparation and Use of Alkylating Agents
    Publication number: 20080294289
    Abstract: The present disclosure provides methods of synthesizing alkylating agents and methods of use.
    Type: Application
    Filed: December 21, 2007
    Publication date: November 27, 2008
    Applicant: The Queen's Medical Center
    Inventor: John L. LIM