Patents by Inventor John L. Murphy

John L. Murphy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10743817
    Abstract: An apparatus for monitoring EMG signals of a patient's laryngeal muscles includes an endotracheal tube having an exterior surface. Conductive electrodes are formed on the endotracheal tube. The conductive electrodes are configured to receive the EMG signals from the laryngeal muscles when the endotracheal tube is placed in a trachea of the patient. At least wireless sensor is formed on the endotracheal tube, and is configured to wirelessly transmit information to a processing apparatus.
    Type: Grant
    Filed: August 31, 2017
    Date of Patent: August 18, 2020
    Assignee: Medtronic Xomed, Inc.
    Inventors: David C. Hacker, Maria Charles Vijay Stanislaus, Wenjeng Li, Dwayne S. Yamasaki, William C. Brunnett, Kevin L. McFarlin, James Britton Hissong, Robert K. Vaccaro, John M. Murphy, Carla A. Pagotto, Tino Schuler
  • Publication number: 20200228906
    Abstract: Loudspeaker parameters are measured separately for various forward and rearward cone displacements, using a test signal that permits measurement of parameters at various degrees of either forward or rearward cone movement. The test signal uses a brief frequency sweep signal such as a logarithmic sweep signal, in combination with a very low frequency (VLF) audio tone having a fundamental frequency below, e.g., 10 Hz. The very low frequency audio tone may have a sine wave shape, a square wave shape or a clipped sine wave shape.
    Type: Application
    Filed: January 10, 2020
    Publication date: July 16, 2020
    Inventors: Brian K. Myers, John L. Murphy
  • Publication number: 20200208161
    Abstract: Methods are provided herein for assembling at least two nucleic acids using a sequence specific nuclease agent (e.g., a gRNA-Cas complex) to create end sequences having complementarity and subsequently assembling the overlapping complementary sequences. The nuclease agent (e.g., a gRNA-Cas complex) can create double strand breaks in dsDNA in order to create overlapping end sequences or can create nicks on each strand to produce complementary overhanging end sequences. Assembly using the method described herein can assemble any nucleic acids having overlapping sequences or can use a joiner oligo to assemble sequences without complementary ends.
    Type: Application
    Filed: March 11, 2020
    Publication date: July 2, 2020
    Applicant: REGENERON PHARMACEUTICALS, INC.
    Inventors: Chris Schoenherr, John McWhirter, Corey Momont, Caitlin L. Goshert, Lynn Macdonald, Gregg S. Warshaw, Jose F. Rojas, Ka-Man Venus Lai, David M. Valenzuela, Andrew J. Murphy
  • Publication number: 20200122303
    Abstract: A method for manufacturing hand tools, such as wrenches. The method generally includes the steps of providing a flat stock, cutting the flat stock into the desired two-dimension blank using a laser, and three-dimensionally machining the laser-cut 2D blank into the desired three-dimensional workpiece. The tool may undergo a heating treatment process and a surface treatment process. In the context of a wrench, the blank may be laser cut with a laser beam oriented to cut generally perpendicularly to the plane of the flat stock. After laser cutting, the handle and interface region between the handle and jaw(s) are machined to provide the desired three-dimensional shape. For example, the three-dimensional shape may be selected to provide a comfortable grip even when applying a high level of force. The wrench jaw may have an optimized geometry calculated so that there is no excess material or “over-designed” regions of the jaw. The wrench jaw has internal corners with optimized radii.
    Type: Application
    Filed: October 19, 2018
    Publication date: April 23, 2020
    Inventors: John A. Amash, Codie A. Bhuyan, Ethan D. Fassezke, Benjamin E. Harrison, Devin L. Henige, Laura R. Murphy
  • Patent number: 10626402
    Abstract: Methods are provided herein for assembling at least two nucleic acids using a sequence specific nuclease agent (e.g., a gRNA-Cas complex) to create end sequences having complementarity and subsequently assembling the overlapping complementary sequences. The nuclease agent (e.g., a gRNA-Cas complex) can create double strand breaks in dsDNA in order to create overlapping end sequences or can create nicks on each strand to produce complementary overhanging end sequences. Assembly using the method described herein can assemble any nucleic acids having overlapping sequences or can use a joiner oligo to assemble sequences without complementary ends.
    Type: Grant
    Filed: March 7, 2019
    Date of Patent: April 21, 2020
    Assignee: Regeneron Pharmaceuticals, Inc.
    Inventors: Chris Schoenherr, John McWhirter, Corey Momont, Caitlin L. Goshert, Lynn MacDonald, Gregg S. Warshaw, Jose F. Rojas, Ka-Man Venus Lai, David M. Valenzuela, Andrew J. Murphy
  • Publication number: 20200111044
    Abstract: A system comprising at least one database and a machine learning computing system to generate optimized learning modules with a track cycle; wherein a track cycle comprises at least one nano learning module, at least one micro learning module, and at least one macro learning module; wherein a track cycle further comprises at least one assessment corresponding to the at least one nano learning module, the at least one micro learning module, or the at least one macro learning module; wherein upon the completion of an assessment, said database is updated to confirm that a learning module, made up of the combination of the at least one nano learning module, at least one micro learning module, and the at least one macro learning module is completed; wherein the machine learning computing system identifies an optimized next track cycle to optimize the next learning module; wherein the machine learning comprises collecting data from at least one user comprising the user's skills and data, and generating optimized ou
    Type: Application
    Filed: October 7, 2019
    Publication date: April 9, 2020
    Inventors: John R. New, JR., Patrick J. Murphy, Steven L. Parker, Joseph L. Narke, Robert J. Cirino
  • Publication number: 20200086042
    Abstract: A system for delivery of a volume of infusible fluid. The system includes a controller configured to calculate a trajectory for delivering infusible fluid, the trajectory comprising at least one volume of fluid, and determine a schedule for delivering the at least one volume of fluid according to the trajectory, wherein the schedule comprising an interval and a volume of infusible fluid for delivery. The system also includes a volume sensor assembly for determining the at least one volume of fluid delivered, wherein the controller recalculates the trajectory based on the volume of fluid delivered.
    Type: Application
    Filed: November 21, 2019
    Publication date: March 19, 2020
    Inventors: Dean Kamen, John M. Kerwin, Gerald M. Guay, Larry B. Gray, Richard J. Lanigan, Stephen L. Fichera, Colin H. Murphy, Thomas F. Soldau, David Blumberg, JR.
  • Publication number: 20200000146
    Abstract: A vaporizer device may include various modular components. The vaporizer device may include a first subassembly. The first subassembly may include a cartridge connector that secures a vaporizer cartridge to the vaporizer device and includes at least two receptacle contacts that electrically communicate with the vaporizer cartridge. The vaporizer device may include a second subassembly. The second subassembly may include a skeleton defining a rigid tray that retains at least a power source. The vaporizer device may also include a third subassembly. The third subassembly may include a plurality of charging contacts that supply power to the power source, and an end cap that encloses an end of the vaporizer device.
    Type: Application
    Filed: June 27, 2019
    Publication date: January 2, 2020
    Inventors: Samuel C. Anderson, Wei-Ling Chang, Brandon Cheung, Steven Christensen, Joseph Chun, Joseph R. Fisher, Jr., Nicholas J. Hatton, Kevin Lomeli, James Monsees, Andrew L. Murphy, Claire O' Malley, John R. Pelochino, Hugh Pham, Vipul V. Rahane, Matthew J. Taschner, Val Valentine, Kenneth Wong
  • Patent number: 10485922
    Abstract: A system for delivery of a volume of infusible fluid. The system includes a controller configured to calculate a trajectory for delivering infusible fluid, the trajectory comprising at least one volume of fluid, and determine a schedule for delivering the at least one volume of fluid according to the trajectory, wherein the schedule comprising an interval and a volume of infusible fluid for delivery. The system also includes a volume sensor assembly for determining the at least one volume of fluid delivered, wherein the controller recalculates the trajectory based on the volume of fluid delivered.
    Type: Grant
    Filed: November 14, 2016
    Date of Patent: November 26, 2019
    Assignee: DEKA Products Limited Partnership
    Inventors: Dean Kamen, John M. Kerwin, Gerald M. Guay, Larry B. Gray, Richard J. Lanigan, Stephen L. Fichera, Colin H. Murphy, Thomas F. Soldau, David Blumberg, Jr.
  • Publication number: 20190183424
    Abstract: An apparatus for monitoring EMG signals of a patient's laryngeal muscles includes an endotracheal tube having an exterior surface. Conductive electrodes are formed on the endotracheal tube. The conductive electrodes are configured to receive the EMG signals from the laryngeal muscles when the endotracheal tube is placed in a trachea of the patient. At least wireless sensor is formed on the endotracheal tube, and is configured to wirelessly transmit information to a processing apparatus.
    Type: Application
    Filed: February 25, 2019
    Publication date: June 20, 2019
    Applicant: MEDTRONIC XOMED, INC.
    Inventors: David C. Hacker, Maria Charles Vijay Stanislaus, Wenjeng Li, Dwayne S. Yamasaki, William C. Brunnett, Kevin L. McFarlin, James Britton Hissong, Robert K. Vaccaro, John M. Murphy, Carla A. Pagotto, Tino Schuler
  • Patent number: 10238767
    Abstract: The invention relates provides synthetic medical adhesives which exploit plant derivatives to form covalent bonds with amines and thiols on tissue surfaces.
    Type: Grant
    Filed: July 25, 2013
    Date of Patent: March 26, 2019
    Assignee: DSM IP ASSETS, B.V.
    Inventors: John L. Murphy, Jeffrey L. Dalsin, Arinne N. Lyman, Laura L. Bremer, Joel L. Broussard, Neil Winterbottom, Justin T. Koepsel
  • Publication number: 20170312384
    Abstract: The invention describes new synthetic medical adhesives and antifouling coatings which exploit the key components of natural marine mussel adhesive proteins.
    Type: Application
    Filed: August 25, 2015
    Publication date: November 2, 2017
    Inventors: Bruce P. Lee, Sunil Silvary, John L. Murphy
  • Publication number: 20170266353
    Abstract: Synthesis methods for creating polymeric compounds comprising phenyl derivatives (PD), or PDp i.e., polymers modified with PD, with desired surface active effects are described. The polymer backbone of PDp has structural or performance features that can be tailored to control physical properties of PDp, allowing it to be useful for different applications i.e., tissue adhesives or sealants, adhesion promoting coatings, and antifouling coatings.
    Type: Application
    Filed: May 13, 2015
    Publication date: September 21, 2017
    Inventors: John L MURPHY, Christopher P RADANO, Jeffrey L. DALSIN, Justin T. KOEPSEL
  • Publication number: 20170056548
    Abstract: The invention describes new synthetic medical adhesives and antifouling coatings which exploit the key components of natural marine mussel adhesive proteins.
    Type: Application
    Filed: August 25, 2015
    Publication date: March 2, 2017
    Inventors: Bruce P. Lee, Sunil Silvary, John L. Murphy
  • Publication number: 20160346424
    Abstract: The invention describes new synthetic medical adhesives and films which exploit the key components of natural marine mussel adhesive proteins.
    Type: Application
    Filed: April 25, 2016
    Publication date: December 1, 2016
    Inventors: Bruce P. Lee, Jeffrey L. Dalsin, John L. Murphy, Laura Vollenweider, Arinne N. Lyman, Fangmin Xu, Jediah White, William D. Lew, Michael Brodie
  • Patent number: 9320826
    Abstract: The invention describes new synthetic medical adhesives and films which exploit the key components of natural marine mussel adhesive proteins.
    Type: Grant
    Filed: November 9, 2011
    Date of Patent: April 26, 2016
    Assignee: KENSEY NASH CORPORATION
    Inventors: Bruce P. Lee, Jeffrey L. Dalsin, John L. Murphy, Laura Vollenweider, Arinne N. Lyman, Fangmin Xu, Jediah White, William D. Lew, Michael Brodie
  • Publication number: 20160032047
    Abstract: The invention provides compositions that use phenylic derivatives to provide adhesive properties. Selection of phenylic derivatives with linkers or linking groups, and the linkages between the linkers or linking groups with polyalkylene oxides, provided herein may be configured to control curing time, biodegradation and/or swelling.
    Type: Application
    Filed: March 14, 2014
    Publication date: February 4, 2016
    Inventors: John L MURPHY, Jeffrey L DALSIN, Arinne N LYMAN, Christopher P RADANO
  • Patent number: 9115289
    Abstract: The invention describes new synthetic medical adhesives and antifouling coatings which exploit the key components of natural marine mussel adhesive proteins.
    Type: Grant
    Filed: February 5, 2010
    Date of Patent: August 25, 2015
    Assignee: KENSEY NASH CORPORATION
    Inventors: Bruce P. Lee, Sunil Silvary, John L. Murphy
  • Patent number: 8916652
    Abstract: The invention describes families of compounds that utilize multihydroxyl phenyl groups to provide adhesive properties. Selection of the multihydroxy phenyl group along with linkers or linking groups and the linkages between the linkers or linking groups with polyalkylene oxides, provides materials that can be engineered to afford controllable curing time, biodegradation and/or swelling.
    Type: Grant
    Filed: February 20, 2012
    Date of Patent: December 23, 2014
    Assignee: Kensey Nash Corporation
    Inventors: Jeffrey L. Dalsin, Bruce P. Lee, Laura Vollenweider, Sunil Silvary, John L. Murphy, Fangmin Xu, Amanda Spitz, Arinne Lyman
  • Patent number: 8754285
    Abstract: The invention relates generally to thin-film adhesive materials suitable for various applications. In particular, the present invention provides pliable viscoelastic thin-films configured to form strong water-resistant adhesive bonds to various surface types.
    Type: Grant
    Filed: July 14, 2010
    Date of Patent: June 17, 2014
    Assignee: Kensey Nash Corporation
    Inventors: Bruce P. Lee, Jediah White, Fangmin Xu, John L. Murphy, Laura Vollenweider