Patents by Inventor John L. Murtha

John L. Murtha has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Oral sustained release pharmaceutical formulation and process
    Patent number: 5073380
    Abstract: A pharmaceutical sustained release tablet or tablet layer is formed by making a wet granulation, using povidone (PVP) in water or alcohol-water as the granulating fluid which is mixed with a pharmaceutical active, hydroxyethyl cellulose, a wicking agent e.g. microcrystalline cellulose, then drying and milling the granulation and blending with dry powdered smoothness enhancer, e.g. povidone, erosion promoter, e.g. pregelatinized starch, additional wicking agent, lubricant e.g. magnesium stearate and glidant e.g. silicon dioxide, and compressing the resultant granulation into a tablet with a smooth outer surface, which tablet provides, upon administration, a slow release of the pharmaceutical active.
    Type: Grant
    Filed: July 9, 1990
    Date of Patent: December 17, 1991
    Assignee: McNeil-PPC, Inc.
    Inventors: Suresh R. Babu, Robert Glinecke, John L. Murtha, Galen W. Radebaugh
  • Oral sustained release pharmaceutical formulation and process
    Patent number: 5004613
    Abstract: A pharmaceutical sustained release tablet or tablet layer is formed by making a wet granulation, using povidone (PVP) in water or alcohol-water as the granulating fluid which is mixed with a pharmaceutical active, hydroxyethyl cellulose, a wicking agent e.g. microcrystalline cellulose, then drying and milling the granulation and blending with dry powdered erosion promotor, e.g. pregelantinized starch, additional wicking agent, lubricant e.g. magnesium stearate and glidant e.g. silicon dioxide, and compressing the resultant granulation, which upon administration results in a slow release of the pharmaceutical active.
    Type: Grant
    Filed: August 11, 1989
    Date of Patent: April 2, 1991
    Assignee: McNeil-PPC, Inc.
    Inventors: Galen W. Radebaugh, John L. Murtha, Robert Glinecke
  • Oral sustained release acetaminophen formulation and process
    Patent number: 4968509
    Abstract: An acetaminophen-sustained release tablet or tablet layer is formed by making a wet granulation, using Povidone (PVP) in water or alcohol-water as the granulating fluid which is mixed with acetaminophen, hydroxyethyl cellulose, a wicking agent e.g. microcrystalline cellulose, then drying and milling the granulation and blending with dry powdered erosion promoter, e.g. pregelatinized starch, wicking agent, lubricant e.g. magnesium stearate and glidant e.g. silicon dioxide, and compressing the resultant granulation, which upon administration results in a slow release of the acetaminophen.
    Type: Grant
    Filed: January 19, 1989
    Date of Patent: November 6, 1990
    Assignee: McNeilab, Inc.
    Inventors: Galen W. Radebaugh, John L. Murtha, Robert Glinecke
  • Oral sustained release acetaminophen formulation and process
    Patent number: 4820522
    Abstract: An acetaminophen-sustained release tablet or tablet layer is formed by making a wet granulation, using Povidone (PVP) in water or alcohol-water as the granulating fluid which is mixed with acetaminophen, hydroxyethyl cellulose, a wicking agent e.g. microcrystalline cellulose, then drying and milling the granulation and blending with dry powdered erosion promoter, e.g. pregelatinized starch, wicking agent, lubricant e.g. magnesium stearate and glidant e.g. silicon dioxide, and compressing the resultant granulation, which upon administration results in a slow release of the acetaminophen.
    Type: Grant
    Filed: July 27, 1987
    Date of Patent: April 11, 1989
    Assignee: McNeilab, Inc.
    Inventors: Galen W. Radebaugh, John L. Murtha, Robert Glinecke