Abstract: Compounds, compositions, and methods for treatment and/or prevention of at least one disease, disorder, and/or condition by inhibiting binding of an E-selectin, galectin-3, or E-selectin and galectin-3 to ligands are disclosed. For example, heterobifunctional inhibitors of E-selectin and galectin-3 are described and pharmaceutical compositions comprising at least one such agent is described.

Abstract: In some embodiments, an affixed group of pharmaceutical vials with frangible connectors includes: a plurality of pharmaceutical vials arranged as a group of pharmaceutical vials, each of the plurality of pharmaceutical vials shaped and positioned to minimize a total volume of the group of pharmaceutical vials, each of the pharmaceutical vials including at least one external side with a surface configured to reversibly mate with a corresponding external side and a surface of an adjacent pharmaceutical vial; and a plurality of frangible connectors, wherein at least one frangible connector is affixed to the surface of at least two of the plurality of pharmaceutical vials within the group of pharmaceutical vials, and at least one frangible connector is affixed to each of the plurality of pharmaceutical vials.

Abstract: Dithiocarbamate and phosphite containing fertilizers, as well as methods of making and methods of using these fertilizers, are disclosed.

Abstract: Dithiocarbamate and phosphite containing fertilizers, as well as methods of making and methods of using these fertilizers, are disclosed.

Abstract: A toolholder apparatus includes a head, a cutting tool mounting fixture attached to the head for holding the cutting tool, and a floating roller assembly pivotally mounted relative to the head. These components are arranged and constructed so that during the cutting of a workpiece with the cutting tool the floating roller assembly can pivot about a pivotal axis relative to the head to allow the floating roller assembly to align with the workpiece. A mechanism is also provided for accomplishing the initial adjustment of alignment of the cutting tool with the rotating workpiece. This mechanism includes a cylindrical shaft extending from the head, and having an eccentric cam follower lug extending transversely from the shaft. A mounting block has a cylindrical bore disposed therethrough, and the shaft is received through the bore of the mounting block. A cam piece is slideably disposed within the mounting block to rotate the shaft as the cam piece slides relative to the mounting block.

Abstract: A toolholder apparatus includes a head, a cutting tool mounting fixture attached to the head for holding the cutting tool, and a floating roller assembly pivotally mounted relative to the head. These components are arranged and constructed so that during the cutting of a workpiece with the cutting tool the floating roller assembly can pivot about a pivotal axis relative to the head to allow the floating roller assembly to align with the workpiece. A mechanism is also provided for accomplishing the initial adjustment of alignment of the cutting tool with the rotating workpiece. This mechanism includes a cylindrical shaft extending from the head, and having an eccentric cam follower lug extending transversely from the shaft. A mounting block has a cylindrical bore disposed therethrough, and the shaft is received through the bore of the mounting block. A cam piece is slideably disposed within the mounting block to rotate the shaft as the cam piece slides relative to the mounting block.

Abstract: An adjustable toolholder apparatus includes a base plate having a planar supporting surface. A holder body includes a bottom planar supported surface which slideably engages and rests upon the supporting surface of the base plate. A linear position adjuster provides a linear sliding motion of the holder body upon the base plate. An angular position adjuster provides a rotational sliding motion of the holder body upon the base plate. The holder body has a wedge shaped recess within which is received a wedge shaped carrier block. A vertically adjustable column supports the wedge shaped carrier block from the base plate to adjust a height of the cutting tool. After linear and angular adjustment of the cutting tool relative to the base plate, the wedge shaped carrier block is clamped to the holder body, and the holder body and base plate are clamped to a cross slide to fix the cutting tool in its final desired position.

Abstract: A toolholder apparatus includes a head, a cutting tool mounting fixture attached to the head for holding the cutting tool, and a floating roller assembly pivotally mounted relative to the head. These components are arranged and constructed so that during the cutting of a workpiece with the cutting tool the floating roller assembly can pivot about a pivotal axis relative to the head to allow the floating roller assembly to align with the workpiece. A mechanism is also provided for accomplishing the initial adjustment of alignment of the cutting tool with the rotating workpiece. This mechanism includes a cylindrical shaft extending from the head, and having an eccentric cam follower lug extending transversely from the shaft. A mounting block has a cylindrical bore disposed therethrough, and the shaft is received through the bore of the mounting block. A cam piece is slideably disposed within the mounting block to rotate the shaft as the cam piece slides relative to the mounting block.

Abstract: The present invention relates to a composition comprising an antimicrobial effective amount of a biocide selected from the group consisting of aromatic 2-N-hydroxy-thiourea and N-hydroxy-quinazolinone, and derivatives and combinations thereof, and at least one component selected from the group consisting of soaps, shampoos, skin-care medicaments, cosmetics, plastics and paints. Also disclosed is a novel process for making the biocide.

Abstract: The present invention relates to a composition comprising an antimicrobial effective amount of a biocide selected from the group consisting of aromatic 2-N-hydroxy-thiourea and N-hydroxy-quinazolinone, and derivatives and combinations thereof, and at least one component selected from the group consisting of soaps, shampoos, skin-care medicaments, cosmetics, plastics and paints. Also disclosed is a novel process for making the biocide.

Abstract: A hybrid air conditioning system which simultaneously dehumidifies and cools air using standard vapor-compression equipment and aqueous solutions of liquid desiccant. By using a circulating liquid desiccant and an adiabatic humidifier, a more efficient refrigerant cycle is utilized. Moreover, conditioned air can be delivered at the same temperature and absolute humidity as conventional vapor-compression systems but without overworking the compressor.

Abstract: A hybrid air conditioning system which simultaneously dehumidifies and cools air using standard vapor-compression equipment and aqueous solutions of liquid desiccant. By using a circulating liquid desiccant and an adiabatic humidifier, a more efficient refrigerant cycle is utilized. Moreover, conditioned air can be delivered at the same temperature and absolute humidity as conventional vapor-compression systems but without overworking the compressor.

Abstract: The present invention relates, in general, to an electronic and measuirng circuits are located remotely from the test head. A low device count circuit at each pin performs the necessary high speed switching. The force and measure lines are relatively long, but the signal rates are low enough to be accurately transmitted. The only high rate signals are on lines coupled to the gates of FET switches at the test head. Thus, multiple pin, high speed testing can be accomplished using relatively small and inexpensive test heads.

Abstract: The specification discloses a cutting tool (10) having a cutting insert (18) mounted thereon. A clamp (20) is secured to a tool body (12) by a screw (24) and spring (62) interconnection, and a clamp tip (22) extends from the clamp (20) towards the insert (18). Structure, such as a groove (25) or shoulder (82), is formed in or on the upper surface of the cutting insert (18) for interengaging with the clamp tip (22) to secure the cutting insert on the cutting tool (10). Lateral shoulders (30) and (32) and a body surface (52) engage and align the insert (18) thereby, preventing lateral, rearward, and rotational movement of the insert (18).