Abstract: Compounds of formula I, ##STR1## in which A is a 5 or 6 membered, fully unsaturated, carbocyclic or heterocyclic ring,B is a 5 or 6 membered, fully unsaturated, nitrogen containing heterocyclic ring,X is NR.sub.19, O or S,R.sub.19 is hydrogen or alkyl optionally substituted by --OCOR,n is 0 or 1,R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7, R.sub.8, R.sub.9 and R.sub.10 have various significances,R.sub.1 and R.sub.2, are hydrogen or alkyl or together with the ring carbon atoms to which they are attached, form a benzene or pyridine ring, which ring carries substituents R.sub.15, R.sub.16, R.sub.17 and R.sub.18,R.sub.15, R.sub.16, R.sub.17 and R.sub.18, have varioussignificances, with certain provisos are described.Processes for making the compounds and pharmaceutical formulations containing them, e.g. for the treatment of conditions including excess gastric acid secretion, are also described.

Abstract: There are described compounds of formula I, ##STR1## in which A is a benzene or heterocyclic ring, y is 0 or 1,L is a group containing 1 or 2 carbon atoms, or is a single bond,R.sub.9 and R.sub.10 have a variety of significances, e.g.R.sub.10 may form part of a double bond with L, orthe group --NR.sub.9 R.sub.10 forms a ring carrying substituents R.sub.1 and R.sub.8, orwhen L is a single bond --NR.sub.10 and R.sub.8 may form a ring carrying substituents R.sub.16 to R.sub.25, orthe group --LNR.sub.9 R.sub.10 forms a heterocyclic ring carrying substituents R.sub.26 to R.sub.33,R.sub.1 to R.sub.8 and R.sub.16 to R.sub.33 have a variety of significancesn is 0, 1 or 2,x is 3, 4 or 5,X is S, O or NR.sub.15,R.sub.15 is hydrogen, --COR, --COOR or alkyl optionally substituted by --OCOR,and certain provisos.Processes for making the compounds and pharmaceutical formulations containing them, e.g. for the treatment of conditions involving excess gastric acid secretion, are also described.

Abstract: There are provided benzopyrans of formula I, ##STR1## wherein the substituents, R.sub.5 -R.sub.8 and EA are as defined in the specification. These compounds are useful as anti-asthmatic agents.

Abstract: There are provided benzopyrans of formula I ##STR1## wherein R.sub.6 and R.sub.7 together form the chain --CHOCH.dbd.(A.sub.1 E.sub.1)--O-- in which --O-- is attached to R.sub.7,R.sub.5 represents hydrogen,R.sub.8 represents propyl,A represents a single bond,A.sub.1 represents a single bond, phenylene or (CH.sub.2).sub.m,m represents an integer from 1 to 10 inclusive,E and E.sub.1, which may be the same or different, independently represent --COOH, 5H-tetrazolyl, or CONR.sub.24 R.sub.25, wherein R.sub.24 and R.sub.25, which may be the same or different, represent hydrogen or alkyl of C.sub.1 to C.sub.6 ;provided that when A.sub.1 represents a single bond, then E.sub.1 represents 5H-tetrazolyl or CONR.sub.24 R.sub.25, and their pharmaceutically acceptable salts, all of which are useful as anti-asthmatics.

Abstract: There are described compounds of formula I, ##STR1## in which an adjacent pair of R.sub.5, R.sub.6, R.sub.7 and R.sub.8 form a chain --CZC(G.sub.1).dbd.(G.sub.2)--Z--,R.sub.4, R.sub.9 and the remainder of R.sub.5, R.sub.6, R.sub.7 and R.sub.8, which may be the same or different, each represent hydrogen, alkyl, halogen, alkenyl, --NO.sub.2, --NR.sub.1 R.sub.2, --OR.sub.3, --S(O).sub.n R.sub.3 ; or alkyl substituted by hydroxy, amino, alkoxy or carbonyl oxygen,n is 0, 1 or 2,R.sub.1 and R.sub.2, which may be the same or different, each represent hydrogen, alkyl, --CONHR.sub.3, phenyl or phenyl substituted by alkyl or halogen, or R.sub.1 and R.sub.2 together with the nitrogen atom to which they are attached form a 5 or 6 membered heterocyclic ring,R.sub.3 represents hydrogen, alkyl, alkenyl or phenyl,one of G.sub.1 and G.sub.

Abstract: There is described the mono salt of 6-methylamino-4-oxo-10-propyl-4H-pyrano[3,2-g]-quinoline-2,8-dicarboxylic acid with a strongly basic cation.There is also described an aqueous solution of 6-methylamino-4-oxo-10-propyl-4H-pyrano[3,2-g]quinoline-2,8-dicarboxylic acid the solution being at a pH of from 4 to 8.The salts and solutions are useful as pharmaceuticals, e.g. in the treatment of allergies.