Abstract: In some aspects, the disclosure relates to compositions and methods useful for the modulating the function of the nuclear pore and/or nucleocytoplasmic transport (NCT). In some embodiments, the disclosure relates to methods of treatment of a neurodegenerative disease (e.g., amyotrophic lateral sclerosis).

Abstract: A multi-catalytic material that includes a polyelectrolyte membrane and methods of preparing the same are provided herein.

Abstract: A multi-catalytic material that includes a polyelectrolyte membrane and methods of preparing the same are provided herein.

Abstract: The invention encompasses methods and products related to genotyping. The method of genotyping of the invention is based on the use of single nucleotide polymorphisms (SNPs) to perform high throughput genome scans. The high throughput method can be performed by hybridizing SNP allele-specific oligonucleotides and a reduced complexity genome (RCG). The invention also relates to methods of preparing the SNP specific oligonucleotides and RCGs, methods of fingerprinting, determining allele frequency for a SNP, characterizing tumors, generating a genomic classification code for a genome, identifying previously unknown SNPs, and related compositions and kits.

Abstract: An electric game apparatus (‘the first apparatus’) for use by a player in a live combat simulation, the apparatus including a firearm-like device, transmission means configured to transmit first and second signals, and a target receiver, the first signal being transmitted towards a target receiver of a like apparatus of another game player (‘second apparatus’) in response to firing said device when aimed at the target receiver of the second apparatus, the second signal being transmitted in response to the target receiver of the first apparatus being hit by a said first signal from a second apparatus to indicate the hit to that other player.

Abstract: Nanocomposite fibers containing one or more carbon nanotubes encapsulated in an polysaccharide gel matrix.

Abstract: An electric game apparatus (‘the first apparatus’) for use by a player in a live combat simulation, the apparatus including a firearm-like device, transmission means configured to transmit first and second signals, and a target receiver, the first signal being transmitted towards a target receiver of a like apparatus of another game player (‘second apparatus’) in response to firing said device when aimed at the target receiver of the second apparatus, the second signal being transmitted in response to the target receiver of the first apparatus being hit by a said first signal from a second apparatus to indicate the hit to that other player.

Abstract: A game maze for playing war games, combat games and the like is erected from a series of inflatable wall modules which can be deflated for transportation and storage. The wall modules are grouped together as desired to form passageways or cells within the maze. Some of the modules are formed with door openings through which game players can pass and window openings through which game players can view other parts of the maze and other participants.

Abstract: The invention encompasses methods and products related to genotyping. The method of genotyping of the invention is based on the use of single nucleotide polymorphisms (SNPs) to perform high throughput genome scans. The high throughput method can be performed by hybridizing SNP allele-specific oligonucleotides and a reduced complexity genome (RCG). The invention also relates to methods of preparing the SNP specific oligonucleotides and RCGs, methods of fingerprinting, determining allele frequency for a SNP, characterizing tumors, generating a genomic classification code for a genome, identifying previously unknown SNPs, and related compositions and kits.

Abstract: A method and system for capturing a written signature is presented. A tip of an infrared transmitting pen transmits an infrared signal to infrared sensors that are aligned along two sides of a rectangular writing surface. As a person's signature is written with the infrared transmitting pen, the sensors capture the written signature.

Abstract: A system and method for providing an expandable, configurable and adaptable POS terminal having a common chassis in relation to a retailer's requirements without requiring a retailer to reconfigure or swap out the logic board of the POS terminal is provided. The POS terminal of the present invention includes a common chassis forming an interior compartment for housing the internal components of the POS terminal including a PC motherboard and riser cards having POS functionality. The footprint, appearance and connectivity of the POS terminal is also adaptable to reflect retailer requirements without the need to modify or exchange the logic board of the POS terminal. Such a system and method allows for improved in-field upgrades, improvements and extensions; automatic detection of configured technology via panel cards and riser cards; coupling and mixing of a plurality of connective technologies; and customization of unique connector configurations and external preferences for a specific retail environment.

Abstract: A method, computer program product and system for storing or updating authentications, e.g., passwords, in a boot code image, i.e., binary executable boot code, stored within a Read Only Memory (ROM), e.g., flash ROM, of a terminal from a remote central site. An authentication may be stored in the boot code image in a terminal from a central site by creating a file comprising a boot code image storing the authentication at the central site and then storing the created file in ROM in the terminal. The file may be downloaded from a server at the central site to the terminal. An authentication in the boot code image in a terminal may be updated remotely from a central site by updating the file associated with the boot code image, i.e., updating the authentication, at the central site and then downloading the updated file to the terminal.

Abstract: A method and system for authenticating print media includes providing a digital memory physically associated with a holder of print media, and storing data in the digital memory, which data is adapted to be authenticated to allow use of the print media. In a preferred embodiment the system and method are capable of detecting the print medium present in a printer and adjusting printing characteristics of a printer with respect to the specific print medium present.

Abstract: The invention relates to high throughput methods for determining haplotypes. The high throughput methods are based on hybridization, fluorescence detection, primer extension, MALDI TOF, and HPLC.

Abstract: A method and system for automatically determining a configuration of an I/O connector panel is disclosed. The method and system comprises the steps of providing information about the capabilities of the connector card to a memory within the connector card, examining the information in the memory. The method and system further includes downloading at least one driver to a system coupled to the I/O connector panel based upon the examined information. In a preferred embodiment, an EEROM is provided in the connector panel that contains details on connectors that are installed and the EEROM is easy to update. The I/O capabilities of a platform (as determined by an I/O panel or other hardware that contains some identification mechanism that defines the I/O capabilities) is within the connector card. This mechanism is then used to determine what software to “preload” into a system so that as new I/O devices are added in the field, the required software for these devices has already been preloaded.

Abstract: The invention encompasses methods and products related to genotyping. The method of genotyping of the invention is based on the use of single nucleotide polymorphisms (SNPs) to perform high throughput genome scans. The high throughput method can be performed by hybridizing SNP allele-specific oligonucleotides and a reduced complexity genome (RCG). The invention also relates to methods of preparing the SNP specific oligonucleotides and RCGs, methods of fingerprinting, determining allele frequency for a SNP, characterizing tumors, generating a genomic classification code for a genome, identifying previously unknown SNPs, and related compositions and kits.

Abstract: The invention encompasses methods and products related to genotyping. The method of genotyping of the invention is based on the use of single nucleotide polymorphisms (SNPs) to perform high throughput genome scans. The high throughput method can be performed by hybridizing SNP allele-specific oligonucleotides and a reduced complexity genome (RCG). The invention also relates to methods of preparing the SNP specific oligonucleotides and RCGs, methods of fingerprinting, determining allele frequency for a SNP, characterizing tumors, generating a genomic classification code for a genome, identifying previously unknown SNPs, and related compositions and kits.

Abstract: A hot melt pressure sensitive adhesive composition comprising a tackified ethylene-propylene rubber modified with a copolymer of a styrene ethylene-propylene block copolymer and/or a styrene ethylene -butylene block is provided. The pressure sensitive adhesive exhibits high cohesive strength and adhesion to polar and apolar surfaces.