Patents by Inventor John Leo Grutsch, Jr.

John Leo Grutsch, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cyclic peptide antifungal agents
    Patent number: 6043341
    Abstract: The present invention provides phosphonylating agents and phosphonylation conditions that are compatible with the acid- and base-sensitive compounds and which promote a regioselective and reproducible conversion to a phosphonate compound. Also provided are intermediates that may be used to prepare phosphonate derivatives of cyclic peptides antifungal agent and a process for converting the phosphonates to the desired phosphonic acid prodrugs.
    Type: Grant
    Filed: August 4, 1998
    Date of Patent: March 28, 2000
    Assignee: Eli Lilly & Co.
    Inventors: Uko Effiong Udodong, John Leo Grutsch, Jr., Marvin Martin Hansen, Allen Robert Harkness, Daniel Edward Verral, II