Abstract: The disclosure provides anti-Siglec-9 antibodies and bispecific and multispecific antibodies that target Siglec-9 and Siglec-7, and therapeutic methods comprising administering such antibodies to a cancer patient or a patient having an autoimmune disease or other disorder in which it is desirable to inhibit an immune response.

Abstract: The present disclosure provides anti-Siglec-6 antibodies and their use in treating and preventing mast cell-mediated disorders, as well as compositions and kits comprising the anti-Siglec-6 antibodies.

Abstract: The invention provides humanized anti-Siglec-8 antibodies and their use in treating and preventing eosinophil-mediated disorders and/or mast cell-mediated disorders, as well as compositions and kits comprising the humanized anti-Siglec-8 antibodies.

Abstract: A method for generating a visual illustration of data organized in a multiway graph is provided. In an embodiment, a computer system maintains a plurality of nodes and edges within a multiway graph and displays a visual user interface with a first node positioned at the center of the visual user interface and child nodes positioned at radially symmetric positions surrounding the first node. The computer system receives a first input that specifies a selection of a first child node. In response to receiving the first input, the computer system updates the visual user interface to display: the first node, positioned at the center; the child nodes, positioned at radially symmetric positions surrounding the first node; the first child node positioned below the first node; and grandchild nodes of the first child node, displayed as polygons positioned at radially symmetric positions around a circular area surrounding the child nodes.

Abstract: A method for generating a visual illustration of data organized in a multiway graph is provided. In an embodiment, a computer system maintains a plurality of nodes and edges within a multiway graph and displays a visual user interface with a first node positioned at the center of the visual user interface and child nodes positioned at radially symmetric positions surrounding the first node. The computer system receives a first input that specifies a selection of a first child node. In response to receiving the first input, the computer system updates the visual user interface to display: the first node, positioned at the center; the child nodes, positioned at radially symmetric positions surrounding the first node; the first child node positioned below the first node; and grandchild nodes of the first child node, displayed as polygons positioned at radially symmetric positions around a circular area surrounding the child nodes.

Abstract: A method for generating a visual illustration of data organized in a multiway graph is provided. In an embodiment, a computer system maintains a plurality of nodes and edges within a multiway graph and displays a visual user interface with a first node positioned at the center of the visual user interface and child nodes positioned at radially symmetric positions surrounding the first node. The computer system receives a first input that specifies a selection of a first child node. In response to receiving the first input, the computer system updates the visual user interface to display: the first node, positioned at the center; the child nodes, positioned at radially symmetric positions surrounding the first node; the first child node positioned below the first node; and grandchild nodes of the first child node, displayed as polygons positioned at radially symmetric positions around a circular area surrounding the child nodes.

Abstract: A method for generating a visual illustration of data organized in a multiway graph is provided. In an embodiment, a computer system maintains a plurality of nodes and edges within a multiway graph and displays a visual user interface with a first node positioned at the center of the visual user interface and child nodes positioned at radially symmetric positions surrounding the first node. The computer system receives a first input that specifies a selection of a first child node. In response to receiving the first input, the computer system updates the visual user interface to display: the first node, positioned at the center; the child nodes, positioned at radially symmetric positions surrounding the first node; the first child node positioned below the first node; and grandchild nodes of the first child node, displayed as polygons positioned at radially symmetric positions around a circular area surrounding the child nodes.

Abstract: The invention provides humanized anti-Siglec-8 antibodies and their use in treating and preventing eosinophil-mediated disorders and/or mast cell-mediated disorders, as well as compositions and kits comprising the humanized anti-Siglec-8 antibodies.

Abstract: A method for generating a visual illustration of data organized in a multiway graph is provided. In an embodiment, a computer system maintains a plurality of nodes and edges within a multiway graph and displays a visual user interface with a first node positioned at the center of the visual user interface and child nodes positioned at radially symmetric positions surrounding the first node. The computer system receives a first input that specifies a selection of a first child node. In response to receiving the first input, the computer system updates the visual user interface to display: the first node, positioned at the center; the child nodes, positioned at radially symmetric positions surrounding the first node; the first child node positioned below the first node; and grandchild nodes of the first child node, displayed as polygons positioned at radially symmetric positions around a circular area surrounding the child nodes.

Abstract: A method for generating a visual illustration of data organized in a multiway graph is provided. In an embodiment, a computer system maintains a plurality of nodes and edges within a multiway graph and displays a visual user interface with a first node positioned at the center of the visual user interface and child nodes positioned at radially symmetric positions surrounding the first node. The computer system receives a first input that specifies a selection of a first child node. In response to receiving the first input, the computer system updates the visual user interface to display: the first node, positioned at the center; the child nodes, positioned at radially symmetric positions surrounding the first node; the first child node positioned below the first node; and grandchild nodes of the first child node, displayed as polygons positioned at radially symmetric positions around a circular area surrounding the child nodes.

Abstract: The invention provides humanized anti-Siglec-8 antibodies and their use in treating and preventing eosinophil-mediated disorders and/or mast cell-mediated disorders, as well as compositions and kits comprising the humanized anti-Siglec-8 antibodies.

Abstract: The invention provides humanized anti-Siglec-8 antibodies and their use in treating and preventing eosinophil-mediated disorders and/or mast cell-mediated disorders, as well as compositions and kits comprising the humanized anti-Siglec-8 antibodies.

Abstract: The invention provides humanized anti-Siglec-8 antibodies and their use in treating and preventing eosinophil-mediated disorders and/or mast cell-mediated disorders, as well as compositions and kits comprising the humanized anti-Siglec-8 antibodies.

Abstract: Aspects of a method and system for integrated blocker detection and automatic gain control are provided. In this regard, a communication device may generate one or more first signal strength indications based on a strength of a received signal at a first point in the analog front-end of the communication device. The communication device may generate one or more second signal strength indications based on a strength of the received signal at a second point in a digital processing module of the communication device. The first point in the analog front-end may be an input or an output of a down-conversion mixer. The second point in the digital processing module may be an output of an analog-to-digital converter or an output of a channel selection filter. The communication device may control, utilizing the first signal strength indication(s) and the second signal strength indication(s), a gain of one or more components of the communication device.

Abstract: Aspects of a method and system for integrated blocker detection and automatic gain control are provided. In this regard, a communication device may generate one or more first signal strength indications based on a strength of a received signal at a first point in the analog front-end of the communication device. The communication device may generate one or more second signal strength indications based on a strength of the received signal at a second point in a digital processing module of the communication device. The first point in the analog front-end may be an input or an output of a down-conversion mixer. The second point in the digital processing module may be an output of an analog-to-digital converter or an output of a channel selection filter. The communication device may control, utilizing the first signal strength indication(s) and the second signal strength indication(s), a gain of one or more components of the communication device.

Abstract: A method and apparatus for pressurizing a fillable-structure, wherein a space defined by the pump, an untraversed plunger, and a closure is a volume, Vt, and a stop to limit the travel of the plunger along the pump so a volume, Vb, remains within the space defined by the pump, the fully traversed plunger, and the closure. Traversal or manipulation of the plunger expresses gas from the pump to the Tillable-structure wherein the pressurization of the fillable-structure is limited by the ratio of Vt to Vb whereby the fillable-structure can not be pressurized beyond a pressure Pmax.

Abstract: Embodiments of the invention are generally directed to a system and method for a service processor architecture. The service processor provides an extensible execution environment for a platform (or other device) that is accessible when the host system is non-functional. In an embodiment, the service processor has one or more platform-independent external interfaces to provide a communications link between the service processor and one or more management resources.