Patents by Inventor John Liddle

John Liddle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PYRAZOLOPYRIDINES AND PYRAZOLOPYRIDAZINES ADN ANTIDIABETICS
    Publication number: 20060223800
    Abstract: The present invention includes compound of formula (I), or a derivative thereof wherein Y is CH or N; R1 is unsubstituted or substituted alkyl, unsubstituted or substituted cycloalkyl, unsubstituted or substituted alkenyl, unsubstituted or substituted cycloalkenyl, unsubstituted or substituted aryl, aralkyl wherein the aryl and the alkyl moieties may each independently be unsubstituted or substituted, aralkenyl wherein the aryl, and alkenyl moieties may each independently be unsubstituted or substituted, unsubstituted or substituted heterocyclyl, or heterocyclylalkyl wherein the heterocyclcyl and the alkyl moieties may each inedepently be unsubstituted or substituted; and R2 is unsubstituted aryl or unsubstituted or substituted or substituted heteroaryl. Additionally the present invention inlcudes a process for preparing such a compound, a pharmaceutical composition containing such a compound, and the use of such a compound in medicine.
    Type: Application
    Filed: June 6, 2006
    Publication date: October 5, 2006
    Inventors: Stephen Garland, David Haigh, Deidre Mary Hickey, John Liddle, David Smith, Robert Ward, Jason Witherington
  • Pyrazolopyridines and pyrazolopyridazines as antidiabetics
    Patent number: 7109199
    Abstract: The present invention includes compound of formula (I), or a derivative thereof, wherein Y is CH or N; R1 is unsubstituted or substituted alkyl, unsubstituted or substituted cycloalkyl, unsubstituted or substituted alkenyl, unsubstituted or substituted cycloalkenyl, unsubstituted or substituted aryl, aralkyl wherein the aryl and the alkyl moieties may each independently be unsubstituted or substituted, aralkenyl wherein the aryl, and alkenyl moieties may each independently be unsubstituted or substituted, unsubstituted or substituted heterocyclyl, or heterocyclylalkyl wherein the heterocyclyl and the alkyl moieties may each independently be unsubstituted or substituted; and R2 is unsubstituted aryl or unsubstituted or substituted or substituted heteroaryl. Additionally the present invention includes a process for preparing such a compound, a pharmaceutical composition containing such a compound, and the use of such a compound in medicine.
    Type: Grant
    Filed: September 19, 2001
    Date of Patent: September 19, 2006
    Assignee: SmithKline Beecham Corporation
    Inventors: Stephen Garland, David Haigh, Deidre Mary Bernadette Hickey, John Liddle, David Glynn Smith, Robert William Ward, Jason Witherington
  • Substituted diketopiperazines as oxytocin antagonists
    Publication number: 20050148572
    Abstract: A method of treating or preventing diseases or conditions mediated through the action of oxytocin which comprises administering to a mammal in need thereof of an effective amount of a compound of the formula (I) and/or a physiologically acceptable derivative thereof, wherein the substituents have the meaning given in the description. Disclosed are also novel compounds of formula (I) and processes for their preparation.
    Type: Application
    Filed: December 20, 2002
    Publication date: July 7, 2005
    Inventors: Alan Borthwick, Richard Hatley, Deirdre Hickey, John Liddle, David Livermore, Andrew Mason, Neil Miller, Fabrizio Nerozzi, Steven Sollis, Anna Szardenings, Paul Wyatt
  • Heterocyclic derivatives of glycinamide and their medical use
    Publication number: 20050043335
    Abstract: Compounds of the formula (I) are inhibitors of the enzyme Lp-PLA2? and are of use in therapy, in particular for treating atherosclerosis.
    Type: Application
    Filed: November 8, 2002
    Publication date: February 24, 2005
    Inventors: Richard Elliott, Deidre Hickey, Robert Ife, Colin Leach, John Liddle, Ivan Pinto, Stephen Smith, Steven Stanway
  • Pyridone, pyridazone and triazone derivatives as lp-pla2 inhibitors
    Publication number: 20050020832
    Abstract: Compounds of the formula (I) are inhibitors of the enzyme Lp-PLA2 and are of use in therapy, in particular for treating atherosclerosis.
    Type: Application
    Filed: November 8, 2002
    Publication date: January 27, 2005
    Inventors: Stephen Fell, Deirdre Hickey, Colin Leach, John Liddle, Ivan Pinto, Stephen Smith
  • Pyridinone derivatives for treatment of atherosclerosis
    Publication number: 20050014793
    Abstract: Compounds of formula (I): are inhibitors of the enzyme Lp-PLA2 and are of use in therapy, in particular for treating atherosclerosis. Compounds of formula (I): are inhibitors of the enzyme Lp-PLA2 and are of use in therapy, in particular for treating atherosclerosis.
    Type: Application
    Filed: July 28, 2004
    Publication date: January 20, 2005
    Inventors: Deirdre Hickey, Robert Ife, Colin Leach, John Liddle, Ivan Pinto, Stephen Smith, Steven Stanway
  • Pyridinone derivatives for treatment of atherosclerosis
    Publication number: 20040063753
    Abstract: Compounds of formula (I): are inhibitors of the enzyme Lp-PLA2 and are of use in therapy, in particular for treating atherosclerosis.
    Type: Application
    Filed: September 9, 2003
    Publication date: April 1, 2004
    Inventors: Deirdre Mary Bernadette Hickey, Robert John Ife, Colin Andrew Leach, John Liddle, Ivan Leo Pinto, Stephen Allan Smith, Steven James Stanway
  • Pyrazolopyridines and pyrazolopyridazines as antidabetics
    Publication number: 20040019052
    Abstract: The present invention includes compound of formula (I), 1
    Type: Application
    Filed: August 14, 2003
    Publication date: January 29, 2004
    Inventors: Stephen Garland, David Haigh, Deidre Mary Bernadette Hickey, John Liddle, David Glynn Smith, Robert William Ward, Jason Witherington