Patents by Inventor John Linton
John Linton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220088561Abstract: A method of registering a location of a dispenser array in relation to a microfluidic array is provided. One of the dispenser array and the microfluidic array can be movable in relation to the frame, and the other can be fixed relative to the frame. Their relative positions can be identified by a set of coordinates. Identification of a fiducial marker can occur in a manner permitting the fiducial reference to appear in a first position of a field of view of a first camera when the dispenser array or the microfluidic array is in an alignment position. Quantities related to a vector displacement from the alignment position to a fixed position on the microfluidic array or the dispenser array can be identified. Quantities determined can be used to guide positioning of the dispenser array relative to the microfluidic array.Type: ApplicationFiled: October 19, 2021Publication date: March 24, 2022Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Colin BRENAN, Jamie CHO, Javier GARCIA, Robert HESS, Tanya KANIGAN, Arrin KATZ, Namyong KIM, John LINTON, Shailesh SRIVASTAVA, Karl YODER
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Patent number: 11154834Abstract: A differentially coated device for conducting a plurality of nano-volume specified reactions, the device comprising a platen having at least one exterior surface modified to a specified physicochemical property, a plurality of nano-volume channels, each nanovolume channel having at least one interior surface in communication with the at least one exterior surface. Methods for preparing and using such devices are also provided, as well as a method of registering a location of a dispenser array in relation to a microfluidic array. Quantities related to a vector displacement from the alignment position to a fixed position on the one of the dispenser array and the microfluidic array is determined. The quantities thus determined are used to guide positioning of the dispenser array relative to the microfluidic array.Type: GrantFiled: February 25, 2019Date of Patent: October 26, 2021Assignee: LIFE TECHNOLOGIES CORPORATIONInventors: Colin Brenan, Jamie Cho, Javier Garcia, Robert Hess, Tanya Kanigan, Arrin Katz, Namyong Kim, John Linton, Shailesh Srivastava, Karl Yoder
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Patent number: 10974247Abstract: An interface is provided for storing microfluidic samples in a nanoliter sample chip. A fluid access structure provides a fluid access region to a selected subset of sample wells from an array of sample wells. A fluid introduction mechanism introduces a sample fluid to the fluid access region so that the sample wells in the selected subset are populated with the sample fluid without the unselected sample wells being populated with the sample fluid.Type: GrantFiled: August 31, 2018Date of Patent: April 13, 2021Assignee: Life Technologies CorporationInventors: Tanya S. Kanigan, Steve Smith, John Linton, Robert Hess, Karl Yoder, Colin J. H. Brenan
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Publication number: 20200055016Abstract: A differentially coated device for conducting a plurality of nano-volume specified reactions, the device comprising a platen having at least one exterior surface modified to a specified physicochemical property, a plurality of nano-volume channels, each nano-volume channel having at least one interior surface in communication with the at least one exterior surface that is selectively coated with an optionally dissolvable coating agent physisorbed to at least one interior surface, wherein the optionally dissolvable coating agent comprises a coating agent and a first component for the plurality of specified reactions. Methods for preparing and using such devices are also provided, as well as a method of registering a location of a dispenser array in relation to a microfluidic array. A first one of the dispenser array and the microfluidic array is movable in relation to the frame, and the other of the first one of the dispenser array and the microfluidic array is fixed relative to the frame.Type: ApplicationFiled: February 25, 2019Publication date: February 20, 2020Inventors: Colin BRENAN, Jamie CHO, Javier GARCIA, Robert HESS, Tanya Kanigan, Arrin Katz, Namyong KIM, John LINTON, Shailesh SRIVASTAVA, Karl Yoder
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Publication number: 20190118173Abstract: An interface is provided for storing microfluidic samples in a nanoliter sample chip. A fluid access structure provides a fluid access region to a selected subset of sample wells from an array of sample wells. A fluid introduction mechanism introduces a sample fluid to the fluid access region so that the sample wells in the selected subset are populated with the sample fluid without the unselected sample wells being populated with the sample fluid.Type: ApplicationFiled: August 31, 2018Publication date: April 25, 2019Inventors: Tanya S. KANIGAN, Steve SMITH, John LINTON, Robert HESS, Karl YODER, Colin J. H. BRENAN
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Patent number: 10213761Abstract: A differentially coated device for conducting a plurality of nano-volume specified reactions, the device comprising a platen having at least one exterior surface modified to a specified physicochemical property, a plurality of nano-volume channels, each nano-volume channel having at least one interior surface in communication with the at least one exterior surface that is selectively coated with an optionally dissolvable coating agent physisorbed to at least one interior surface, wherein the optionally dissolvable coating agent comprises a coating agent and a first component for the plurality of specified reactions. Methods for preparing and using such devices are also provided, as well as a method of registering a location of a dispenser array in relation to a microfluidic array. A first one of the dispenser array and the microfluidic array is movable in relation to the frame, and the other of the first one of the dispenser array and the microfluidic array is fixed relative to the frame.Type: GrantFiled: June 9, 2014Date of Patent: February 26, 2019Assignee: Life Technologies CorporationInventors: Colin J. H. Brenan, Jamie Cho, Javier Garcia, Robert Hess, Tanya S. Kanigan, Arrin Katz, Namyong Kim, John Linton, Shailesh Srivastava, Karl Yoder
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Publication number: 20180361345Abstract: The invention features methods of making devices, or “platens”, having a high-density array of through-holes, as well as methods of cleaning and refurbishing the surfaces of the platens. The invention further features methods of making high-density arrays of chemical, biochemical, and biological compounds, having many advantages over conventional, lower-density arrays. The invention includes methods by which many physical, chemical or biological transformations can be implemented in serial or in parallel within each addressable through-hole of the devices. Additionally, the invention includes methods of analyzing the contents of the array, including assaying of physical properties of the samples.Type: ApplicationFiled: May 14, 2018Publication date: December 20, 2018Inventors: Robert Hess, John Linton, Tanya S. Kanigan, Colin Brenan, Can Ozbal
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Patent number: 10065189Abstract: An interface is provided for storing microfluidic samples in a nanoliter sample chip. A fluid access structure provides a fluid access region to a selected subset of sample wells from an array of sample wells. A fluid introduction mechanism introduces a sample fluid to the fluid access region so that the sample wells in the selected subset are populated with the sample fluid without the unselected sample wells being populated with the sample fluid.Type: GrantFiled: February 22, 2016Date of Patent: September 4, 2018Assignee: Life Technologies CorporationInventors: Tanya S. Kanigan, Steve Smith, John Linton, Robert Hess, Karl Yoder, Colin John Herbert Brenan
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Patent number: 9968903Abstract: The invention features methods of making devices, or “platens”, having a high-density array of through-holes, as well as methods of cleaning and refurbishing the surfaces of the platens. The invention further features methods of making high-density arrays of chemical, biochemical, and biological compounds, having many advantages over conventional, lower-density arrays. The invention includes methods by which many physical, chemical or biological transformations can be implemented in serial or in parallel within each addressable through-hole of the devices. Additionally, the invention includes methods of analyzing the contents of the array, including assaying of physical properties of the samples.Type: GrantFiled: April 18, 2016Date of Patent: May 15, 2018Assignee: Life Technologies CorporationInventors: Robert Hess, John Linton, Tanya S. Kanigan, Colin Brenan, Can Ozbal
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Publication number: 20160332133Abstract: The invention features methods of making devices, or “platens”, having a high-density array of through-holes, as well as methods of cleaning and refurbishing the surfaces of the platens. The invention further features methods of making high-density arrays of chemical, biochemical, and biological compounds, having many advantages over conventional, lower-density arrays. The invention includes methods by which many physical, chemical or biological transformations can be implemented in serial or in parallel within each addressable through-hole of the devices. Additionally, the invention includes methods of analyzing the contents of the array, including assaying of physical properties of the samples.Type: ApplicationFiled: April 18, 2016Publication date: November 17, 2016Inventors: Robert HESS, John LINTON, Tanya S. KANIGAN, Colin BRENAN, Can OZBAL
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Patent number: 9428800Abstract: A system for holding at least one of sample and reagent for analysis. The system includes a pair of parallel covers, at least one of which is light transmissive, of which pair a light transmissive cover forms a top, and of which pair the other forms a bottom. A frame is disposed between the covers to define, in relation to the covers, an interior volume. The frame and the covers are associated with one another to form a case, the case being substantially tight to liquids. A microfluidic array is disposed in the interior volume. The array includes a sheet of material having a pair of opposed surfaces, a thickness, and a plurality of through-holes running through the thickness between the surfaces, the through-holes containing at least one of sample and reagent.Type: GrantFiled: March 3, 2014Date of Patent: August 30, 2016Assignee: Life Technologies CorporationInventors: John Linton, Arrin Katz, Colin Brenan, Karl Yoder, Robert Hess, Leila Madrone, Robert Ellis, Tanya Kanigan, Kristine Friesen, Thomas Morrison, Javier Garcia
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Publication number: 20160210875Abstract: Various embodiments for prescribing electronic resources based on observational assessments are described. One example system includes a communication unit for sending and receiving data, a recommendation engine, and an assignment engine. The recommendation engine receives observation data related to a target subject, identifies one or more electronic resources that correspond to the observation data, and provides data describing the one or more electronic resources for display to an observer. The recommendation engine is coupled to the communication unit to provide the data representing the one or more electronic resources. The assignment engine receives an assignment request requesting an assignment of at least one electronic resource from the one or more electronic resources to the target subject for completion. The assignment engine also assigns the at least one electronic resource to the target subject. The assignment engine is coupled to the communication unit to receive the assignment request.Type: ApplicationFiled: January 5, 2016Publication date: July 21, 2016Inventors: Chet Dee Linton, Cory John Linton, Jonathan E. Smalley, Derris Todd Moore
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Publication number: 20160167044Abstract: An interface is provided for storing microfluidic samples in a nanoliter sample chip. A fluid access structure provides a fluid access region to a selected subset of sample wells from an array of sample wells. A fluid introduction mechanism introduces a sample fluid to the fluid access region so that the sample wells in the selected subset are populated with the sample fluid without the unselected sample wells being populated with the sample fluid.Type: ApplicationFiled: February 22, 2016Publication date: June 16, 2016Inventors: Tanya S. KANIGAN, Steve SMITH, John LINTON, Robert HESS, Karl YODER, Colin John Herbert BRENAN
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Patent number: 9314764Abstract: The invention features methods of making devices, or “platens”, having a high-density array of through-holes, as well as methods of cleaning and refurbishing the surfaces of the platens. The invention further features methods of making high-density arrays of chemical, biochemical, and biological compounds, having many advantages over conventional, lower-density arrays. The invention includes methods by which many physical, chemical or biological transformations can be implemented in serial or in parallel within each addressable through-hole of the devices. Additionally, the invention includes methods of analyzing the contents of the array, including assaying of physical properties of the samples.Type: GrantFiled: July 21, 2011Date of Patent: April 19, 2016Assignee: Life Technologies CorporationInventors: Robert Hess, John Linton, Tanya S. Kanigan, Colin Brenan, Can Ozbal
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Patent number: 9266108Abstract: An interface is provided for storing microfluidic samples in a nanoliter sample chip. A fluid access structure provides a fluid access region to a selected subset of sample wells from an array of sample wells. A fluid introduction mechanism introduces a sample fluid to the fluid access region so that the sample wells in the selected subset are populated with the sample fluid without the unselected sample wells being populated with the sample fluid.Type: GrantFiled: September 30, 2013Date of Patent: February 23, 2016Assignee: Life Technologies CorporationInventors: Tanya S. Kanigan, Steve Smith, John Linton, Robert Hess, Karl Yoder, Colin John Herbert Brenan
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Patent number: 9262746Abstract: Various embodiments for prescribing electronic resources based on observational assessments are described. One example system includes a communication unit for sending and receiving data, a recommendation engine, and an assignment engine. The recommendation engine receives observation data related to a target subject, identifies one or more electronic resources that correspond to the observation data, and provides data describing the one or more electronic resources for display to an observer. The recommendation engine is coupled to the communication unit to provide the data representing the one or more electronic resources. The assignment engine receives an assignment request requesting an assignment of at least one electronic resource from the one or more electronic resources to the target subject for completion. The assignment engine also assigns the at least one electronic resource to the target subject. The assignment engine is coupled to the communication unit to receive the assignment request.Type: GrantFiled: August 9, 2012Date of Patent: February 16, 2016Assignee: SCHOOL IMPROVEMENT NETWORK, LLCInventors: Chet Dee Linton, Cory John Linton, Jonathan E. Smalley, Derris Todd Moore
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Publication number: 20150038377Abstract: A liquid dispenser for a microfluidic assay system is described. The dispenser includes at least one transfer pin for transferring a microfluidic sample of liquid to a target receptacle. A pin tip at one end of the transfer pin is structured to cooperate with an opening in the target receptacle. The tip uses a high voltage potential to transfer the sample from the pin to the receptacle.Type: ApplicationFiled: July 15, 2014Publication date: February 5, 2015Inventors: Leila Madrone, John Linton, Colin John Herbert Brenan
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Publication number: 20150011436Abstract: A differentially coated device for conducting a plurality of nano-volume specified reactions, the device comprising a platen having at least one exterior surface modified to a specified physicochemical property, a plurality of nano-volume channels, each nano-volume channel having at least one interior surface in communication with the at least one exterior surface that is selectively coated with an optionally dissolvable coating agent physisorbed to at least one interior surface, wherein the optionally dissolvable coating agent comprises a coating agent and a first component for the plurality of specified reactions. Methods for preparing and using such devices are also provided, as well as a method of registering a location of a dispenser array in relation to a microfluidic array. A first one of the dispenser array and the microfluidic array is movable in relation to the frame, and the other of the first one of the dispenser array and the microfluidic array is fixed relative to the frame.Type: ApplicationFiled: June 9, 2014Publication date: January 8, 2015Inventors: Colin J. H. Brenan, Jamie Cho, Javier Garcia, Robert Hess, Tanya S. Kanigan, Arrin Katz, Namyong Kim, John Linton, Shailesh Srivastava, Karl Yoder
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Patent number: RE46326Abstract: A method and system for providing point-of-sale and point-of-delivery and/or distribution of products in a restricted access unit near the customer. The method and system utilize products equipped with radio frequency tags and reduce the effects of energy sharing, shadowing, and nulls. In one embodiment, a plurality of RF tagged products are placed within a refrigerator, cabinet, or other micro-warehouse that has a door or opening that can detect access to the micro-warehouse. In one embodiment, one or more antennas are positioned within the door. Each antenna may have a transmission line of sight and be configured to emit a signal at predefined frequencies. Each antenna generates an electromagnetic field within the micro-warehouse. In one embodiment, the products are positioned in one or more bins, compartments, or similar devices located within the micro-warehouse such that at least two of the plurality of products are spaced a distance from each other to reduce energy sharing.Type: GrantFiled: January 22, 2015Date of Patent: February 28, 2017Assignee: Promega CorporationInventors: Michael Dearing, Gediminas Vidugiris, William A. Linton, John Linton, Julia E. Krueger
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Patent number: RE47599Abstract: A method and system for providing point-of-sale and point-of-delivery and/or distribution of products in a restricted access unit near the customer. The method and system utilize products equipped with radio frequency tags and reduce the effects of energy sharing, shadowing, and nulls. In one embodiment, a plurality of RF tagged products are placed within a refrigerator, cabinet, or other micro-warehouse that has a door or opening that can detect access to the micro-warehouse. In one embodiment, one or more antennas are positioned within the door. Each antenna may have a transmission line of sight and be configured to emit a signal at predefined frequencies. Each antenna generates an electromagnetic field within the micro-warehouse. In one embodiment, the products are positioned in one or more bins, compartments, or similar devices located within the micro-warehouse such that at least two of the plurality of products are spaced a distance from each other to reduce energy sharing.Type: GrantFiled: June 14, 2017Date of Patent: September 10, 2019Assignee: PROMEGA CORPORATIONInventors: Michael Dearing, Gediminas Vidugiris, William A. Linton, John Linton, Julia E. Krueger