Patents by Inventor John Lokhnauth

John Lokhnauth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Lipid multiparticulate formulations
    Patent number: 11324699
    Abstract: Disclosed are various embodiments of lipid multiparticulate compositions comprising at least one active agent, a low flow point excipient, and a high flow point excipient.
    Type: Grant
    Filed: November 24, 2015
    Date of Patent: May 10, 2022
    Assignee: Capsugel Belgium NV
    Inventors: Christopher Diorio, John Lokhnauth, Chang Lee
  • Curcumin solid lipid particles and methods for their preparation and use
    Patent number: 10166187
    Abstract: Solid lipid particles comprising a lipid hydrophobic matrix and from about 5 wt. % to about 30 wt. % of curcumin, and methods of making and treatment thereof.
    Type: Grant
    Filed: October 18, 2017
    Date of Patent: January 1, 2019
    Assignee: Capsugel Belgium NV
    Inventors: Christopher Diorio, John Lokhnauth
  • CURCUMIN SOLID LIPID PARTICLES AND METHODS FOR THEIR PREPARATION AND USE
    Publication number: 20180036248
    Abstract: Solid lipid particles comprising a lipid hydrophobic matrix and from about 5 wt. % to about 30 wt. % of curcumin, and methods of making and treatment thereof.
    Type: Application
    Filed: October 18, 2017
    Publication date: February 8, 2018
    Applicant: Capsugel Belgium NV
    Inventors: Christopher Diorio, John Lokhnauth
  • LIPID MULTIPARTICULATE FORMULATIONS
    Publication number: 20170354599
    Abstract: Disclosed are various embodiments of lipid multiparticulate compositions comprising at least one active agent, a low flow point excipient, and a high flow point excipient.
    Type: Application
    Filed: November 24, 2015
    Publication date: December 14, 2017
    Applicant: Capsugel Belgium NV
    Inventors: Christopher Diorio, John Lokhnauth, Chang Lee
  • Peripheral opioid receptor antagonists and uses thereof
    Patent number: 9724343
    Abstract: The present invention provides a compound of formua I: wherein X?, R1, and R2 are as defined herein, and compositions thereof.
    Type: Grant
    Filed: September 26, 2016
    Date of Patent: August 8, 2017
    Assignee: Wyeth, LLC
    Inventors: Nataliya Bazhina, George Joseph Donato, III, Steven R. Fabian, John Lokhnauth, Sreenivasulu Megati, Charles Melucci, Christian Ofslager, Niketa Patel, Galen Radebaugh, Syed M. Shah, Jan Szeliga, Huyi Zhang, Tianmin Zhu
  • PERIPHERAL OPIOID RECEPTOR ANTAGONISTS AND USES THEREOF
    Publication number: 20170007597
    Abstract: The present invention provides a compound of formula I: wherein X?, R1, and R2 are as defined herein, and compositions thereof.
    Type: Application
    Filed: September 26, 2016
    Publication date: January 12, 2017
    Inventors: Nataliya Bazhina, George Joseph Donato, III, Steven R. Fabian, John Lokhnauth, Sreenivasulu Megati, Charles Melucci, Christian Ofslager, Niketa Patel, Galen Radebaugh, Syed M. Shah, Jan Szeliga, Huyi Zhang, Tianmin Zhu
  • Peripheral opioid receptor antagonists and uses thereof
    Patent number: 9492445
    Abstract: The present invention provides a compound of formula I: wherein X?, R1, and R2 are as defined herein, and compositions thereof.
    Type: Grant
    Filed: September 30, 2015
    Date of Patent: November 15, 2016
    Assignee: Wyeth, LLC
    Inventors: Nataliya Bazhina, George Joseph Donato, III, Steven R. Fabian, John Lokhnauth, Sreenivasulu Megati, Charles Melucci, Christian Ofslager, Niketa Patel, Galen Radebaugh, Syed M. Shah, Jan Szeliga, Huyi Zhang, Tianmin Zhu
  • PERIPHERAL OPIOID RECEPTOR ANTAGONISTS AND USES THEREOF
    Publication number: 20160113923
    Abstract: The present invention provides a compound of formula I: wherein X?, R1, and R2 are as defined herein, and compositions thereof.
    Type: Application
    Filed: September 30, 2015
    Publication date: April 28, 2016
    Inventors: Nataliya Bazhina, George Joseph Donato, III, Steven R. Fabian, John Lokhnauth, Sreenivasulu Megati, Charles Melucci, Christian Ofslager, Niketa Patel, Galen Radebaugh, Syed M. Shah, Jan Szeliga, Huyi Zhang, Tianmin Zhu
  • BISMUTH LIQUID FILLED HARD CAPSULES
    Publication number: 20160015647
    Abstract: The present disclosure relates to a new, stable, oil based liquid suspension filled hard capsule dosage form for bismuth salts such as bismuth subsalicylate, a process for its manufacture, methods to deliver bismuth salts to humans or animals via stable hard capsules, and improved methods of treating gastrointestinal disorders with such dosage forms.
    Type: Application
    Filed: March 3, 2014
    Publication date: January 21, 2016
    Applicant: CAPSUGEL BELGIUM NV
    Inventors: Eric Ehrnsperger, Christopher Diorio, Joseph J. Gross, John Lokhnauth
  • CURCUMIN SOLID LIPID PARTICLES AND METHODS FOR THEIR PREPARATION AND USE
    Publication number: 20160000714
    Abstract: Solid lipid particles comprising a lipid hydrophobic matrix and from about 5 wt. % to about 30 wt. % of curcumin, and methods of making and treatment thereof.
    Type: Application
    Filed: March 4, 2014
    Publication date: January 7, 2016
    Applicant: Capsugel Belgium NV
    Inventors: Christopher Diorio, John Lokhnauth
  • Peripheral opioid receptor antagonists and uses thereof
    Patent number: 9180125
    Abstract: The present invention provides a compound of formula I: wherein X?, R1, and R2 are as defined herein, and compositions thereof.
    Type: Grant
    Filed: July 2, 2014
    Date of Patent: November 10, 2015
    Assignee: Wyeth, LLC
    Inventors: Nataliya Bazhina, George Joseph Donato, III, Steven R. Fabian, John Lokhnauth, Sreenivasulu Megati, Charles Melucci, Christian Ofslager, Niketa Patel, Galen Radebaugh, Syed M. Shah, Jan Szeliga, Huyi Zhang, Tianmin Zhu
  • PERIPHERAL OPIOID RECEPTOR ANTAGONISTS AND USES THEREOF
    Publication number: 20150150866
    Abstract: The present invention provides a compound of formula I: wherein X?, R1, and R2 are as defined herein, and compositions thereof.
    Type: Application
    Filed: July 2, 2014
    Publication date: June 4, 2015
    Inventors: Nataliya Bazhina, George Joseph Donato, III, Steven R. Fabian, John Lokhnauth, Sreenivasulu Megati, Charles Melucci, Christian Ofslager, Niketa Patel, Galen Radebaugh, Syed M. Shah, Jan Szeliga, Huyi Zhang, Tianmin Zhu
  • Peripheral opioid receptor antagonists and uses thereof
    Patent number: 8822490
    Abstract: The present invention provides a compound of formula I: wherein X?, R1, and R2 are as defined herein, and compositions thereof.
    Type: Grant
    Filed: May 2, 2013
    Date of Patent: September 2, 2014
    Assignee: Wyeth LLC
    Inventors: Nataliya Bazhina, George Joseph Donato, III, Steven R. Fabian, John Lokhnauth, Sreenivasulu Megati, Charles Melucci, Christian Ofslager, Niketa Patel, Galen Radebaugh, Syed M. Shah, Jan Szeliga, Huyi Zhang, Tianmin Zhu
  • Peripheral opioid receptor antagonists and uses thereof
    Patent number: 8772310
    Abstract: The present invention provides a compound of formula I: wherein X?, R1, and R2 are as defined herein, and compositions thereof; useful as a peripheral mu opioid receptor antagonist.
    Type: Grant
    Filed: November 9, 2012
    Date of Patent: July 8, 2014
    Assignee: Wyeth LLC
    Inventors: Charles K. Melucci, John Lokhnauth
  • Peripheral opioid receptor antagonists and uses thereof
    Patent number: 8455644
    Abstract: The present invention provides a compound of formula I: wherein X?, R1, and R2 are as defined herein, and compositions thereof.
    Type: Grant
    Filed: July 11, 2012
    Date of Patent: June 4, 2013
    Assignee: Wyeth
    Inventors: Nataliya Bazhina, George Joseph Donato, III, Steven R. Fabian, John Lokhnauth, Sreenivasulu Megati, Charles Melucci, Christian Ofslager, Niketa Patel, Galen Radebaugh, Syed M. Shah, Jan Szeliga, Huyi Zhang, Tianmin Zhu
  • Peripheral opioid receptor antagonists and uses thereof
    Patent number: 8420663
    Abstract: The present invention provides a compound of formula I: wherein X?, R1, and R2 are as defined herein, and compositions thereof.
    Type: Grant
    Filed: August 9, 2012
    Date of Patent: April 16, 2013
    Assignee: Wyeth
    Inventors: Nataliya Bazhina, George Joseph Donato, III, Steven R. Fabian, John Lokhnauth, Sreenivasulu Megati, Charles K. Melucci, Christian Ofslager, Niketa Patel, Galen Radebaugh, Syed M. Shah, Jan Szeliga, Huyi Zhang, Tianmin Zhu
  • PERIPHERAL OPIOID RECEPTOR ANTAGONISTS AND USES THEREOF
    Publication number: 20130011929
    Abstract: The present invention provides a compound of formula I: wherein X?, R1, and R2 are as defined herein, and compositions thereof.
    Type: Application
    Filed: July 11, 2012
    Publication date: January 10, 2013
    Applicant: Wyeth
    Inventors: Nataliya Bazhina, George Joseph Donato, III, Steven R. Fabian, John Lokhnauth, Sreenivasulu Megati, Charles Melucci, Christian Ofslager, Niketa Patel, Galen Radebaugh, Syed M. Shah, Jan Szeliga, Huyi Zhang, Tianmin Zhu
  • Peripheral opioid receptor antagonists and uses thereof
    Patent number: 8338446
    Abstract: The present invention provides a compound of formula I: wherein X?, R1, and R2 are as defined herein, and compositions thereof, useful as a peripheral mu opioid receptor antagonist.
    Type: Grant
    Filed: March 28, 2008
    Date of Patent: December 25, 2012
    Assignee: Wyeth LLC
    Inventors: Charles K. Melucci, John Lokhnauth
  • Peripheral Opioid Receptor Antagonists and Uses Thereof
    Publication number: 20120316191
    Abstract: The present invention provides a compound of formula I: wherein X?, R1, and R2 are as defined herein, and compositions thereof.
    Type: Application
    Filed: August 9, 2012
    Publication date: December 13, 2012
    Applicant: Wyeth
    Inventors: Nataliya Bazhina, George Joseph Donato, III, Steven R. Fabian, John Lokhnauth, Sreenivasulu Megati, Charles Melucci, Christian Ofslager, Niketa Patel, Galen Radebaugh, Syed M. Shah, Jan Szeliga, Huyi Zhang, Tianmin Zhu
  • Peripheral opioid receptor antagonists and uses thereof
    Patent number: 8247425
    Abstract: The present invention provides a compound of formula I: wherein X?, R1, and R2 are as defined herein, and compositions thereof.
    Type: Grant
    Filed: September 30, 2009
    Date of Patent: August 21, 2012
    Assignee: Wyeth
    Inventors: Nataliya Bazhina, George Joseph Donato, III, Steven R. Fabian, John Lokhnauth, Sreenivasulu Megati, Charles Melucci, Christian Ofslager, Niketa Patel, Galen Radebaugh, Syed M. Shah, Jan Szeliga, Huyi Zhang, Tianmin Zhu