Patents by Inventor John Lowe

John Lowe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240204798
    Abstract: Provided are systems, methods, and computer program products for protecting AV communications including a sender component and a receiver component from components of an AV system communicating via a shared memory buffer, the sender component configured to send one or more serialized communications to the receiver component, by controlling at least one processor to access a data block storing message data; obtain a first instruction for serializing a communication; obtain a second instruction for computing a CRC checksum; and interleave the CRC checksum with serialized message data to generate a communication within a communication channel, by computing a serialized communication of the message data in the data block based on the first instruction, while concurrently computing the CRC checksum for the message data based on the second instruction.
    Type: Application
    Filed: December 14, 2022
    Publication date: June 20, 2024
    Inventors: Tilmann Wilhelm Wolfgang Ochs, Stuart John Lowe, Dalton Miles Woodard
  • Patent number: 11987580
    Abstract: Provided herein are compounds and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of conditions associated with inhibition of HDAC (e.g., HDAC2). The compounds are bicyclic inhibitors of histone deacetylase, useful for treating neurological disorders, memory or cognitive function disorders or impairments, extinction learning disorders, fungal diseases or infections, inflammatory diseases, hematological diseases, neoplastic diseases, psychiatric disorders, and memory loss.
    Type: Grant
    Filed: December 22, 2021
    Date of Patent: May 21, 2024
    Assignee: Alkermes, Inc.
    Inventors: Nathan Oliver Fuller, John A. Lowe, III
  • Patent number: 11912702
    Abstract: Provided herein are compounds and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of conditions associated with inhibition of HDAC (e.g,. HDAC2).
    Type: Grant
    Filed: December 22, 2021
    Date of Patent: February 27, 2024
    Assignee: Alkermes, Inc.
    Inventors: Nathan Oliver Fuller, John A. Lowe, III
  • Patent number: 11858939
    Abstract: This invention provides compounds that are inhibitors of HDAC2. The compounds (e.g., compounds according to Formula I, II or any of Compounds 100-128 or any of those in Tables 2 or 3) accordingly are useful for treating, alleviating, or preventing a condition in a subject such as a neurological disorder, memory or cognitive function disorder or impairment, extinction learning disorder, fungal disease or infection, inflammatory disease, hematological disease, or neoplastic disease, or for improving memory or treating, alleviating, or preventing memory loss or impairment.
    Type: Grant
    Filed: December 28, 2020
    Date of Patent: January 2, 2024
    Assignee: Alkermes, Inc.
    Inventors: Martin R. Jefson, John A. Lowe, III, Fabian Dey, Andreas Bergmann, Andreas Schoop, Nathan Oliver Fuller
  • Publication number: 20230250165
    Abstract: Purified recombinant polypeptides isolated from Chinese hamster ovary host cells, including antibodies, such as therapeutic antibodies, and methods of making and using such polypeptides are provided.
    Type: Application
    Filed: April 21, 2023
    Publication date: August 10, 2023
    Applicant: Genentech, Inc.
    Inventors: X. Christopher Yu, Saloumeh Kadkhodayan Fischer, Susan C. Fisher, John Lowe, Atia Naim, Ailen M. Sanchez, Christopher A. Teske, Martin Vanderlaan, Annamarie Amurao, Jayme Franklin, Corazon Victa
  • Publication number: 20220340560
    Abstract: Provided herein are compounds and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of conditions associated with inhibition of HDAC (e.g,. HDAC2).
    Type: Application
    Filed: December 22, 2021
    Publication date: October 27, 2022
    Inventors: Nathan Oliver Fuller, John A. Lowe, III
  • Publication number: 20220340558
    Abstract: Provided herein are compounds and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of conditions associated with inhibition of HDAC (e.g., HDAC2).
    Type: Application
    Filed: December 22, 2021
    Publication date: October 27, 2022
    Inventors: Nathan Oliver Fuller, John A. Lowe, III
  • Patent number: 11441521
    Abstract: A valve for m exhaust gas recirculation Mae in an engine includes a first barrel connectable to a first group of cylinders, a second barrel connectable to a second group of cylinders, and a center barrel between the first and second barrels and connectable to an intake of the engine, A poppet valve with two valve heads mounted on a valve stem is provided to open and close openings between the first and second barrels, with one of the valve beads of the poppet valve opening into the center barrel Vanes are provided in the center barrel to direct flow from the opening by the valve bead that opens into the center barrel toward the outlet opening.
    Type: Grant
    Filed: August 15, 2017
    Date of Patent: September 13, 2022
    Assignee: VOLVO TRUCK CORPORATION
    Inventors: Jian Li, John Lowe
  • Publication number: 20220151992
    Abstract: Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of conditions such as depression and related disorders. Orally available formulations and other pharmaceutically acceptable delivery forms of the compounds, including intravenous formulations, are also disclosed.
    Type: Application
    Filed: June 24, 2021
    Publication date: May 19, 2022
    Inventors: John A. Lowe, III, M. Amin Khan
  • Publication number: 20220139047
    Abstract: Many attempts at translating real-time events (e.g., sporting events) to augmented reality (AR)-based, extended or Data Processing Service and Technology Environment cross reality (XR)-based, or virtual reality (VR)-based experiences and environments rely upon mapping captured surface image data (such as video, pictures, etc.) of objects (e.g., balls, players, etc.) onto computer-modeled environments. This surface mapping results in imperfect and unsatisfactory virtual reality experiences for the viewer because the images and sounds do not perfectly correlate to the motion and states of the real-time objects and players. To solve this problem, and create an improved experience fo the virtual spectator, a more accurate and immersive virtual, extended, or aumented reality environment can be created by relying on data from a network system of sensors embedded throughout the real-time environment during the event in question.
    Type: Application
    Filed: February 28, 2020
    Publication date: May 5, 2022
    Applicant: SCORCHED ICE INC.
    Inventors: John LOWE, Bruce WRIGHT, Adile ABBADI-MACINTOSH
  • Patent number: 11286256
    Abstract: Provided herein are compounds and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of conditions associated with inhibition of HDAC (e.g,. HDAC2).
    Type: Grant
    Filed: May 21, 2020
    Date of Patent: March 29, 2022
    Assignee: Alkermes, Inc.
    Inventors: Nathan Oliver Fuller, John A. Lowe, III
  • Patent number: 11225479
    Abstract: Provided herein are compounds and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of conditions associated with inhibition of HDAC (e.g., HDAC2).
    Type: Grant
    Filed: August 31, 2020
    Date of Patent: January 18, 2022
    Assignee: Alkermes, Inc.
    Inventors: Nathan Oliver Fuller, John A. Lowe, III
  • Patent number: 11225475
    Abstract: Provided herein are compounds and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of conditions associated with inhibition of HDAC (e.g., HDAC2).
    Type: Grant
    Filed: August 7, 2018
    Date of Patent: January 18, 2022
    Assignee: Alkermes, Inc.
    Inventors: Nathan Oliver Fuller, John A. Lowe, III
  • Patent number: 11225490
    Abstract: The present invention relates to compounds of Formula I:
    Type: Grant
    Filed: September 6, 2019
    Date of Patent: January 18, 2022
    Assignee: Alkermes Pharma Ireland Limited
    Inventors: Laura Cook Blumberg, John A. Lowe, III, Orn Almarsson, Juan C. Alvarez, Tarek A. Zeidan
  • Publication number: 20210277007
    Abstract: This invention provides compounds that are inhibitors of HDAC2. The compounds (e.g., compounds according to Formula I, II or any of Compounds 100-128 or any of those in Tables 2 or 3) accordingly are useful for treating, alleviating, or preventing a condition in a subject such as a neurological disorder, memory or cognitive function disorder or impairment, extinction learning disorder, fungal disease or infection, inflammatory disease, hematological disease, or neoplastic disease, or for improving memory or treating, alleviating, or preventing memory loss or impairment.
    Type: Application
    Filed: December 28, 2020
    Publication date: September 9, 2021
    Inventors: Martin R. Jefson, John A. Lowe, III, Fabian Dey, Andreas Bergmann, Andreas Schoop, Nathan Oliver Fuller
  • Publication number: 20210276978
    Abstract: Provided herein are compounds of the Formula (I): and pharmaceutically acceptable salts and compositions thereof, which are useful for treating a variety of conditions associated with histone deacetylases (HDAC).
    Type: Application
    Filed: July 12, 2019
    Publication date: September 9, 2021
    Inventors: Nathan Oliver Fuller, John A. Lowe, III
  • Publication number: 20210276977
    Abstract: Provided herein are compounds of Formula I and pharmaceutically acceptable salts and compositions thereof, which are useful for treating a variety of conditions associated with histone deacetylases (HDAC).
    Type: Application
    Filed: July 12, 2019
    Publication date: September 9, 2021
    Inventors: Nathan Oliver Fuller, John A. Lowe, III
  • Patent number: 11077094
    Abstract: Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of conditions such as depression and related disorders. Orally available formulations and other pharmaceutically acceptable delivery forms of the compounds, including intravenous formulations, are also disclosed.
    Type: Grant
    Filed: August 9, 2019
    Date of Patent: August 3, 2021
    Assignee: Aptinyx Inc.
    Inventors: John A. Lowe, III, M. Amin Khan
  • Publication number: 20210155632
    Abstract: Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of conditions such as depression and related disorders. Orally available formulations and other pharmaceutically acceptable delivery forms of the compounds, including intravenous formulations, are also disclosed.
    Type: Application
    Filed: July 2, 2020
    Publication date: May 27, 2021
    Inventors: John A. Lowe, III, M. Amin Khan
  • Publication number: 20210147410
    Abstract: Provided herein are compounds and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of conditions associated with inhibition of HDAC (e.g. HDAC2).
    Type: Application
    Filed: August 7, 2018
    Publication date: May 20, 2021
    Inventors: Nathan Oliver Fuller, John A. Lowe, III