Abstract: A tissue compression cuff comprises a first fastening portion defining one or more openings and at least one band. The at least one band comprises a first end extending from the first fastening portion at a first end, and an opposing second end, the at least one band defining a first diameter at the first end and a second diameter at the second end. The first diameter is larger than the second diameter. A second fastening portion is positioned at the opposing second end of the at least one band. The second end of the at least one band is configured to be inserted through the one or more openings of the first fastening portion. The tissue compression cuff is sized and configured to reduce blood flow through an arteriovenous fistula and made from an electrospun textile made up of biocompatible nanofibers.