Patents by Inventor John Luecke

John Luecke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11268133
    Abstract: Disclosed herein are methods of detecting presence of a gene fusion in a sample from a subject. In some embodiments, the methods of detecting presence of a fusion gene in a sample from a subject utilize a fusion probe that spans the point of fusion between two nucleic acids or genes. In other embodiments, the methods of detecting presence of a fusion gene in a sample from a subject utilize two or more probes that flank the point of fusion between two nucleic acids or genes. In additional embodiments, the methods can include determining the percentage of gene fusion in the sample relative to the first nucleic acid or the second nucleic acid.
    Type: Grant
    Filed: April 8, 2019
    Date of Patent: March 8, 2022
    Assignee: HTG Molecular Diagnostics, Inc.
    Inventors: Bruce A. Seligmann, BJ Kerns, John Luecke, Matt Rounseville, Ihab Botros, Mark Schwartz
  • Publication number: 20190226013
    Abstract: Disclosed herein are methods of detecting presence of a gene fusion in a sample from a subject. In some embodiments, the methods of detecting presence of a fusion gene in a sample from a subject utilize a fusion probe that spans the point of fusion between two nucleic acids or genes. In other embodiments, the methods of detecting presence of a fusion gene in a sample from a subject utilize two or more probes that flank the point of fusion between two nucleic acids or genes. In additional embodiments, the methods can include determining the percentage of gene fusion in the sample relative to the first nucleic acid or the second nucleic acid.
    Type: Application
    Filed: April 8, 2019
    Publication date: July 25, 2019
    Applicant: HTG Molecular Diagnostics, Inc.
    Inventors: Bruce A. Seligmann, BJ Kerns, John Luecke, Matt Rounseville, Ihab Botros, Mark Schwartz
  • Patent number: 10294515
    Abstract: Disclosed herein are methods of detecting presence of a gene fusion in a sample from a subject. In some embodiments, the methods of detecting presence of a fusion gene in a sample from a subject utilize a fusion probe that spans the point of fusion between two nucleic acids or genes, and detecting the fusion probe after nuclease treatment. In other embodiments, the methods of detecting presence of a fusion gene in a sample from a subject utilize two or more probes that flank the point of fusion between two nucleic acids or genes, and detecting these probes after nuclease treatment. In additional embodiments, the methods can include determining the percentage of gene fusion in the sample relative to the first nucleic acid or the second nucleic acid.
    Type: Grant
    Filed: December 7, 2011
    Date of Patent: May 21, 2019
    Assignee: HTG Molecular Diagnostics, Inc.
    Inventors: Bruce Seligmann, BJ Kerns, John Luecke, Matt Rounseville, Ihab Botros, Mark Schwartz
  • Publication number: 20140120540
    Abstract: Disclosed herein are methods of detecting presence of a gene fusion in a sample from a subject. In some embodiments, the methods of detecting presence of a fusion gene in a sample from a subject utilize a fusion probe that spans the point of fusion between two nucleic acids or genes, and detecting the fusion probe after nuclease treatment. In other embodiments, the methods of detecting presence of a fusion gene in a sample from a subject utilize two or more probes that flank the point of fusion between two nucleic acids or genes, and detecting these probes after nuclease treatment. In additional embodiments, the methods can include determining the percentage of gene fusion in the sample relative to the first nucleic acid or the second nucleic acid.
    Type: Application
    Filed: December 7, 2011
    Publication date: May 1, 2014
    Applicant: HTG MOLECULAR DIAGNOSTICS, INC.
    Inventors: Bruce Seligmann, Bj Kerns, John Luecke, Matt Rounseville, Ihab Botros, Mark Schwartz
  • Publication number: 20050067051
    Abstract: A wood chipping or cutting knife assembly providing improved knife stability. A number of control surfaces and other geometric features are provided to stabilize the knife in the assembly. An improved splitter is also provided for the knife assembly.
    Type: Application
    Filed: September 25, 2003
    Publication date: March 31, 2005
    Inventors: Andrew Knappett, Brian Rusaw, Peter Marshall, Bradley Stager, John Luecke
  • Patent number: 5862549
    Abstract: A hospital bed (10) especially adapted for use by a woman giving birth is disclosed. The bed includes a base (11) on which a litter frame (12) is positioned. A lift assembly (14) attached to the base and is connected to a inner frame (50) located inside the litter frame. The lift assembly moves the inner frame and litter frame up and down. The litter frame is pivotally connected to the inner frame so that the litter frame can be selectively moved in the Trendelenburg position.
    Type: Grant
    Filed: March 19, 1997
    Date of Patent: January 26, 1999
    Assignee: Stryker Corporation
    Inventors: Gary Morton, Ned Johnson, John Luecke
  • Patent number: 5774914
    Abstract: A hospital bed (10) especially adapted for use by a woman giving birth is disclosed. The bed includes a base (11) on which a litter frame (12) is positioned. A lift assembly (14) attached to the base and is connected to a inner frame (50) located inside the litter frame. The lift assembly moves the inner frame and litter frame up and down. The litter frame is pivotally connected to the inner frame so that the litter frame can be selectively moved in the Trendelenburg position. A Fowler frame (16) is attached to the litter frame so that it can be both pivoted upwardly from the horizontal and selectively moved toward the seat end of the litter frame. Foot rests (30) are attached to the under surface of the litter frame and can be swung into position as needed. Leg rests (34) are mounted to the under surface of the foot rests and likewise be simply pivoted in place. A foot frame (24) is attached to the seat end of the litter frame and can be readily separated from the rest of the bed.
    Type: Grant
    Filed: January 5, 1996
    Date of Patent: July 7, 1998
    Assignee: Stryker Corporation
    Inventors: Ned Johnson, John Luecke, John Lacey