Abstract: A modular filter system is provided with one or more modules that can be interchangeable, depending upon the specific application or specific health or environmental issue presented. Disclosed combinations can include one or more of any of the following modules in any relative position to one another: (a) a microbiological contaminant mitigation module, preferably in the form of an inverted u-shaped hollow fiber filter module wherein the fibers have ends potted on the downstream side and that consists essentially of hydrophilic fibers for water filtration with a small amount of hydrophobic fibers for venting of entrapped air; (b) a first chemical mitigation module, preferably in the form of an adsorption module comprising carbon or the combination of carbon and a deionization resin; and (c) a second chemical mitigation module, preferably in the form of a deionization resin module.

Abstract: A closure device for use with a container having an open neck finish, including an inner cap having a skirt terminating in an open end which engages the outside diameter of the finish. The inner cap is sized to initially engage the finish. The skirt has circumferentially spaced slits extending, which may function as lyophilization ports, which permit the inner cap to expand upon an axial closing force and engage the bottom of the finish. A liner is positioned in the inner cap proximate the closed end and is compressed against the finish when the cap is moved to alignment with the bottom of the finish. An outer cap is locked on to the inner cap in pre-assembly which then encloses the inner cap after complete assembly to seal and compress the liner between the finish and the inside face of the inner cap.