Abstract: A needle-bearing device for injecting medicinal fluid from a pre-filled vial is provided. After use, the needle is retracted into the body of the device to prevent inadvertent contact with the sharpened end of the needle. In one embodiment, the invention provides a manually actuable button that effectuates retraction of the needle after use. In another embodiment, retraction is effectuated automatically after the injection is complete.

Abstract: A safety needle-bearing device for mixing and injecting medication from a two-chambered cartridge is provided. The device includes a needle that extends through the forward end of a barrel. A two-chambered cartridge is attached to the barrel and contains components of a medication stored separately in the chambers. A plunger in the rearward end of the cartridge can be advanced into the cartridge to combine the separate components and prepare the medication. As the cartridge is advanced forwardly into the barrel, the medication is injected through the needle and into a patient. At the completion of the injection stroke, the cartridge engages a needle retainer to actuate needle retraction. The needle is subsequently retracted to shield the contaminated needle.

Abstract: A method and apparatus are provided for injecting medicine from a pre-filled container into a patient through an injection needle. After use the needle is automatically shielded so that the contaminated needle is protected to prevent inadvertent contact with the needle. The device operates by pumping medicine out of the vial into a transfer chamber. The medicine is the expelled from the transfer chamber into the patient during an injection stroke. At the end of the injection stroke, the needle is released for retraction, and the spring then retracts the needle to shield the needle. Preferably, the device includes an injector assembly and a vial holder assembly. The injector assembly has a needle retainer for releasably retaining te needle in a projecting position against the bias of a spring. The vial holder assembly is attachable with the injector assembly and is operable to transfer the medicine out of the vial and into the transfer chamber to prepare the device for an injection.

Abstract: A catheter insertion device is provided for inserting an over-the-needle catheter. The device includes an insertion needle that is retractable into the housing of the device after use to prevent exposure to the contaminated needle. The needle retainer releasably retains the needle in an extended position against the rearward bias of the biasing element. The needle retainer engages the hub of the catheter so that when the catheter is removed from the insertion device, the needle retainer automatically releases the needle. The biasing element then propels the needle rearwardly into the housing of the device. A method for inserting a catheter is also provided, in which the needle is hooded by the catheter during the insertion procedure.

Abstract: A catheter insertion device is provided for inserting an over-the-needle catheter. The device includes an insertion needle that is retractable into the housing of the device after use to prevent exposure to the contaminated needle. The needle retainer releasably retains the needle in an extended position against the rearward bias of the biasing element. The needle retainer engages the hub of the catheter so that when the catheter is removed from the insertion device, the needle retainer automatically releases the needle. The biasing element then propels the needle rearwardly into the housing of the device. A method for inserting a catheter is also provided, in which the needle is hooded by the catheter during the insertion procedure.

Abstract: A needle-bearing medical device is provided for inserting a guide wire. After use the needle is shielded to render the contaminated needle safe to prevent inadvertent needle sticks. The device includes a housing and a needle having a sharpened tip. A biasing element biases the needle toward a position in which the sharpened tip is shielded. A connector is provided for attaching a fluid collection device to the guide wire insertion device, if desired. A guide is configured for guiding the guide wire through the port and into the needle. A method is also provided for using the medical device, in which the needle is inserted vascularly into a patient. A fluid collection device is attached to the connector of the device and blood is drawn into the fluid collection device to ensure that the needle is properly positioned within a vein or artery of the patient. A guide wire is then inserted into the patient through the device and the needle is retracted to shield the needle.

Abstract: Needle-bearing medical devices are provided for fluid infusion, fluid transfusion, and inserting a guide wire. After use the needle is shielded to render the contaminated needle safe to prevent inadvertent needle sticks. The device includes a housing and a needle having a sharpened tip. A biasing element biases the needle toward a position in which the sharpened tip is shielded.

Abstract: The present invention is a sensor cartridge into which sensors are installed. The sensor cartridge allows the sensors to be easily and reliably installed into a blood analyzer. The sensor assembly has an electrical connector mounted on the rear side of the assembly. A plurality of inner walls within the housing locate a pump tube assembly and right angle fluid coupling within the housing. An opening in the housing receives a first boss which extends from the blood analyzer. A capture/release arm has an opening through which the first boss protrudes. The arm is resiliently held in place such that an inner edge of the opening is captured within a ring-like groove in the boss that extends from the blood analyzer when the cartridge is installed in the blood analyzer. A portion of the arm extends beyond the housing to allow an operator to press the arm and thus release the edge of the arm from the groove in the boss.

Abstract: The present invention provides a staple cartridge assembly adapted for use in a surgical stapler having a cartridge retention portion and an anvil portion which are movable between a closed position and an open position.

Abstract: A trocar for placement in the lumen of a cannula to facilitate inserting the cannula through tissue is disclosed. The trocar has an improved trigger/obturator assembly wherein the trigger comprises tissue cam parts each having (a) planar outer surfaces, and (b) an arcuate end portion at the distal end of the trigger including a distal edge surface that is arcuate about an axis normal to the outer surfaces. The arcuate end portions intersect at edge surfaces which are obscured by the arcuate end portions.

Abstract: The present invention provides a staple cartridge assembly adapted for use in a surgical stapler having a cartridge retention portion and an anvil portion which are movable between a closed position and an open position.

Abstract: A surgical clip for occluding an anatomical structure is disclosed. The clip has a hinge portions and at least three legs projecting from the hinge portion with a slot portion present between at least two of the legs. The hinge portion affords easy removal of the clip.

Abstract: A trocar for placement in the lumen of a cannula to facilitate inserting the cannula through the wall of a body cavity, the trocar comprising an obturator with a point for piercing the wall of the body cavity, and a protective sleeve mounted concentrically around the obturator. The obturator retracts proximally relative to the protective sleeve after the trocar point has penetrated through the wall of the body cavity. The protective sleeve is mounted for axial movement relative to the obturator, retracting proximally in response to drag from the wall of the body cavity as the trocar is advanced through the wall, and advancing distally after the cannula has penetrated through the wall, reducing the drag on the sleeve. The distal advancement of the sleeve triggers the retraction of the obturator.

Abstract: An adapter seal adapted to facilitate the use of a small instrument within a laparoscopic cannula. The adapter seal comprises a body portion formed of elastomeric material, and a relatively rigid insertion guide mounted on the body portion The body portion has an aperture therein adapted to sealingly engage and support the small instrument while permitting movement of the instrument through the aperture The insertion guide has a wall forming a generally conical passageway for guiding small instruments toward the aperture of the body portion. A tether may be provided for holding the adapter seal adjacent the cannula when the body portion is disconnected from the cannula, and the insertion guide may be color-coded to indicate the size aperture through the body portion of the adapter seal.

Abstract: A compound of the general formula ##STR1## in which X represents a chlorine or bromine atom, R.sup.1 represents a hydrogen atom, a C(1-6) alkyl group, a benzyl group or a phenyl group optionally substituted by a C(1-6) alkyl group, and R.sup.2 represents the group CN or the group COOR.sup.3 in which R.sup.3 represents a C(1-6) alkyl group, a process for the preparation of a compound of formula (I), and the use of a compound of formula (I) in the preparation of a compound of the general formula. ##STR2## in which R.sup.1 is as defined above and R.sup.4 represents an amino group or a hydroxyl group.

Abstract: A trocar for placement in the lumen of a cannula to facilitate inserting the cannula through the wall of a body cavity, the trocar comprising an obturator with a point for piercing the wall of the body cavity, and a protective sleeve mounted concentrically around the obturator. The obturator retracts proximally relative to the protective sleeve after the trocar point has penetrated through the wall of the body cavity. The protective sleeve is mounted for axial movement relative to the obturator, retracting proximally in response to drag from the wall of the body cavity as the trocar is advanced through the wall, and advancing distally after the cannula has penetrated through the wall, reducing the drag on the sleeve. The distal advancement of the sleeve triggers the retraction of the obturator.

Abstract: An improved stapler firing assembly and a surgical stapler are disclosed. The stapler comprises structural members having handle parts with opposite sides and jaw parts projecting from the handle parts. The stapler includes a mechanism for releasable engagement between an elongate locking member and the the structural members comprising a lever lock including a hook portion adapted to pass through a slot in a handle part. The lever lock is mounted on the locking member and includes first and second release buttons and actuating means mounting the first and second release buttons on opposite sides of the locking member for movement between first and second positions with respect to the locking member. The stapler firing assembly comprises a pusher adapted to move longitudinally along one of the jaw parts to sequentially press the staples against an anvil.

Abstract: An improved stapler firing assembly and a surgical stapler are disclosed. The stapler comprises structural members having handle parts with opposite sides and jaw parts projecting from the handle parts. The stapler includes a mechanism for releasable engagement between an elongate locking member and the structural members comprising a lever lock including a hook portion adapted to pass through a slot in a handle part. The lever lock is mounted on the locking member and includes first and second release buttons and actuating means mounting the first and second release buttons on opposite sides of the locking member for movement between first and second positions with respect to the locking member. The stapler firing assembly comprises a pusher adapted to move longitudinally along one of the jaw parts to sequentially press the staples against an anvil.

Abstract: A process for the preparation of 3-aminothiophenes or acid-addition salts thereof, which comprises reacting the corresponding 3-oxotetrahydrothiophenes with an acid-addition salt of hydroxylamine in the presence of a polar inert solvent and in the absence of a base at a temperature in the range of from 0.degree. to 200.degree. C.