Patents by Inventor John M. Centanni

John M. Centanni has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HUMAN SKIN EQUIVALENTS EXPRESSING EXOGENOUS POLYPEPTIDES
    Publication number: 20210146012
    Abstract: The present invention relates generally to compositions for wound closure. More specifically, the present invention provides human skin equivalents engineered to express exogenous polypeptides (e.g., antimicrobial polypeptides and keratinocyte growth factor 2) and compositions and methods for making human skin equivalents engineered to express exogenous polypeptides. In addition, the present invention provides methods for treatment of wounds with human skin equivalents engineered to express exogenous polypeptides.
    Type: Application
    Filed: January 5, 2021
    Publication date: May 20, 2021
    Inventors: John M. Centanni, B. Lynn Allen-Hoffmann
  • Human skin equivalents expressing exogenous polypeptides
    Patent number: 10918768
    Abstract: The present invention relates generally to compositions for wound closure. More specifically, the present invention provides human skin equivalents engineered to express exogenous polypeptides (e.g., antimicrobial polypeptides and keratinocyte growth factor 2) and compositions and methods for making human skin equivalents engineered to express exogenous polypeptides. In addition, the present invention provides methods for treatment of wounds with human skin equivalents engineered to express exogenous polypeptides.
    Type: Grant
    Filed: July 16, 2018
    Date of Patent: February 16, 2021
    Assignee: Stratatech Corporation
    Inventors: John M. Centanni, B. Lynn Allen-Hoffman
  • HUMAN SKIN EQUIVALENTS EXPRESSING EXOGENOUS POLYPEPTIDES
    Publication number: 20180311414
    Abstract: The present invention relates generally to compositions for wound closure. More specifically, the present invention provides human skin equivalents engineered to express exogenous polypeptides (e.g., antimicrobial polypeptides and keratinocyte growth factor 2) and compositions and methods for making human skin equivalents engineered to express exogenous polypeptides. In addition, the present invention provides methods for treatment of wounds with human skin equivalents engineered to express exogenous polypeptides.
    Type: Application
    Filed: July 16, 2018
    Publication date: November 1, 2018
    Inventors: John M. Centanni, B. Lynn Allen-Hoffman
  • HUMAN SKIN EQUIVALENTS EXPRESSING EXOGENOUS POLYPEPTIDES
    Publication number: 20170157297
    Abstract: The present invention relates generally to compositions for wound closure. More specifically, the present invention provides human skin equivalents engineered to express exogenous polypeptides (e.g., antimicrobial polypeptides and keratinocyte growth factor 2) and compositions and methods for making human skin equivalents engineered to express exogenous polypeptides. In addition, the present invention provides methods for treatment of wounds with human skin equivalents engineered to express exogenous polypeptides.
    Type: Application
    Filed: December 13, 2016
    Publication date: June 8, 2017
    Inventors: John M. Centanni, B. Lynn Allen-Hoffman
  • Human skin equivalents expressing exogenous polypeptides
    Patent number: 9526748
    Abstract: The present invention relates generally to compositions for wound closure. More specifically, the present invention provides human skin equivalents engineered to express exogenous polypeptides (e.g., antimicrobial polypeptides and keratinocyte growth factor 2) and compositions and methods for making human skin equivalents engineered to express exogenous polypeptides. In addition, the present invention provides methods for treatment of wounds with human skin equivalents engineered to express exogenous polypeptides.
    Type: Grant
    Filed: July 18, 2014
    Date of Patent: December 27, 2016
    Assignee: STRATATECH CORPORATION
    Inventors: John M. Centanni, B. Lynn Allen-Hoffmann
  • Skin substitutes with improved purity
    Patent number: 9295543
    Abstract: The present invention relates to in vitro cultured skin substitutes. In particular, the present invention relates to compositions and methods for the development of cultured skin substitutes using NIKS cells.
    Type: Grant
    Filed: March 15, 2006
    Date of Patent: March 29, 2016
    Assignee: STRATATECH CORPORATION
    Inventors: B. Lynn Allen-Hoffmann, Cathy Ann-Rasmussen Ivarie, John M. Centanni
  • Methods and compositions for selecting cells with increased potency
    Patent number: 9216202
    Abstract: The present invention relates generally to compositions for wound closure. More specifically, the present invention provides human skin equivalents engineered to express exogenous polypeptides (e.g., antimicrobial polypeptides and keratinocyte growth factor 2) and compositions and methods for making human skin equivalents engineered to express exogenous polypeptides. In addition, the present invention provides methods for treatment of wounds with human skin equivalents engineered to express exogenous polypeptides.
    Type: Grant
    Filed: December 9, 2005
    Date of Patent: December 22, 2015
    Assignee: Stratatech Corporation
    Inventors: John M. Centanni, Lynn Allen-Hoffmann
  • HUMAN SKIN EQUIVALENTS EXPRESSING EXOGENOUS POLYPEPTIDES
    Publication number: 20140335064
    Abstract: The present invention relates generally to compositions for wound closure. More specifically, the present invention provides human skin equivalents engineered to express exogenous polypeptides (e.g., antimicrobial polypeptides and keratinocyte growth factor 2) and compositions and methods for making human skin equivalents engineered to express exogenous polypeptides. In addition, the present invention provides methods for treatment of wounds with human skin equivalents engineered to express exogenous polypeptides.
    Type: Application
    Filed: July 18, 2014
    Publication date: November 13, 2014
    Inventors: John M. Centanni, B. Lynn Allen-Hoffmann
  • Human skin equivalents expressing exogenous polypeptides
    Patent number: 8790636
    Abstract: The present invention relates generally to compositions for wound closure. More specifically, the present invention provides human skin equivalents engineered to express exogenous polypeptides (e.g., antimicrobial polypeptides and keratinocyte growth factor 2) and compositions and methods for making human skin equivalents engineered to express exogenous polypeptides. In addition, the present invention provides methods for treatment of wounds with human skin equivalents engineered to express exogenous polypeptides.
    Type: Grant
    Filed: January 4, 2012
    Date of Patent: July 29, 2014
    Assignee: Stratatech Corporation
    Inventors: John M. Centanni, B. Lynn Allen-Hoffmann
  • HUMAN SKIN EQUIVALENTS EXPRESSING EXOGENOUS POLYPEPTIDES
    Publication number: 20120107283
    Abstract: The present invention relates generally to compositions for wound closure. More specifically, the present invention provides human skin equivalents engineered to express exogenous polypeptides (e.g., antimicrobial polypeptides and keratinocyte growth factor 2) and compositions and methods for making human skin equivalents engineered to express exogenous polypeptides. In addition, the present invention provides methods for treatment of wounds with human skin equivalents engineered to express exogenous polypeptides.
    Type: Application
    Filed: January 4, 2012
    Publication date: May 3, 2012
    Applicant: STRATATECH CORPORATION
    Inventors: John M. Centanni, Lynn Allen-Hoffmann
  • Human skin equivalents expressing exogenous polypeptides
    Patent number: 8092531
    Abstract: The present invention relates generally to compositions for wound closure. More specifically, the present invention provides human skin equivalents engineered to express exogenous polypeptides (e.g., antimicrobial polypeptides and keratinocyte growth factor 2) and compositions and methods for making human skin equivalents engineered to express exogenous polypeptides. In addition, the present invention provides methods for treatment of wounds with human skin equivalents engineered to express exogenous polypeptides.
    Type: Grant
    Filed: January 20, 2010
    Date of Patent: January 10, 2012
    Assignee: Stratatech Corporation
    Inventors: John M. Centanni, B. Lynn Allen-Hoffmann
  • Kit for species specific DNA detection
    Patent number: 7888496
    Abstract: The present invention relates to methods and compositions for the identification of species-specific material in pharmaceutical products. In particular, the present invention relates to methods for the identification of species-specific DNA in a population of a different species or following contact (e.g., growth) with cells of a different species.
    Type: Grant
    Filed: December 5, 2008
    Date of Patent: February 15, 2011
    Assignee: Stratatech Corporation
    Inventors: B. Lynn Allen-Hoffmann, John M. Centanni
  • HUMAN SKIN EQUIVALENTS EXPRESSING EXOGENOUS POLYPEPTIDES
    Publication number: 20100119495
    Abstract: The present invention relates generally to compositions for wound closure. More specifically, the present invention provides human skin equivalents engineered to express exogenous polypeptides (e.g., antimicrobial polypeptides and keratinocyte growth factor 2) and compositions and methods for making human skin equivalents engineered to express exogenous polypeptides. In addition, the present invention provides methods for treatment of wounds with human skin equivalents engineered to express exogenous polypeptides.
    Type: Application
    Filed: January 20, 2010
    Publication date: May 13, 2010
    Applicant: STRATATECH CORPORATION
    Inventors: John M. Centanni, Lynn Allen-Hoffmann
  • Human skin equivalents expressing exogenous polypeptides
    Patent number: 7674291
    Abstract: The present invention relates generally to compositions for wound closure. More specifically, the present invention provides human skin equivalents engineered to express exogenous polypeptides (e.g., antimicrobial polypeptides and keratinocyte growth factor 2) and compositions and methods for making human skin equivalents engineered to express exogenous polypeptides. In addition, the present invention provides methods for treatment of wounds with human skin equivalents engineered to express exogenous polypeptides.
    Type: Grant
    Filed: July 30, 2004
    Date of Patent: March 9, 2010
    Assignee: Stratatech Corporation
    Inventors: John M. Centanni, Lynn Allen-Hoffmann
  • Species Specific DNA Detection
    Publication number: 20090176299
    Abstract: The present invention relates to methods and compositions for the identification of species-specific material in pharmaceutical products. In particular, the present invention relates to methods for the identification of species-specific DNA in a population of a different species or following contact (e.g., growth) with cells of a different species.
    Type: Application
    Filed: December 5, 2008
    Publication date: July 9, 2009
    Applicant: STRATATECH CORPORATION
    Inventors: B. Lynn Allen-Hoffmann, John M. Centanni
  • Species specific DNA detection
    Patent number: 7462448
    Abstract: The present invention relates to methods and compositions for the identification of species-specific material in pharmaceutical products. In particular, the present invention relates to methods for the identification of species-specific DNA in a population of a different species or following contact (e.g., growth) with cells of a different species.
    Type: Grant
    Filed: August 1, 2003
    Date of Patent: December 9, 2008
    Assignee: Stratatech Corporation
    Inventors: Lynn Allen-Hoffmann, John M. Centanni
  • Method for increasing luminescence assay sensitivity
    Patent number: 7118878
    Abstract: The invention provides kits and methods for increasing the sensitivity of a bio-luminescent assay, which employ an organic compound that, for instance, reduces luminescence that is not dependent on the presence of an analyte by at least about 10 fold and reduces luminescence that is dependent on the presence of an analyte by less than about 7 fold, reduces luminescence generated by luminogenic molecules not bound to an enzyme by at least about 10 fold and reduces the luminescence generated by luminogenic molecules bound to an enzyme by less than about 7 fold, or reduces autoluminescence by at least about 10 fold and reduces luminescence that is dependent on the presence of an analyte by less than about 7 fold.
    Type: Grant
    Filed: June 9, 2000
    Date of Patent: October 10, 2006
    Assignee: Promega Corporation
    Inventors: Erika Hawkins, John M. Centanni, Jacqueline Sankbeil, Keith V. Wood
  • Method for increasing luminescence assay sensitivity
    Patent number: 7108996
    Abstract: A method for increasing the sensitivity of a bio-luminescent assay comprising carrying out the assay in the presence of an organic compound that reduces luminescence that is not dependent on the presence of an analyte by at least about 10 fold, and that reduces, maintains, or increases the luminescence that is dependent on the presence of an analyte.
    Type: Grant
    Filed: November 18, 2004
    Date of Patent: September 19, 2006
    Assignee: Promega Corporation
    Inventors: Erika Hawkins, John M. Centanni, Jacqueline Sankbeil, Keith V. Wood
  • Kits for increasing luminescence assay sensitivity
    Patent number: 7078181
    Abstract: Assay kits for increasing the sensitivity of luminescent assays are provided that include an organic compound that reduces luminescence that is not dependent on the presence of an analyte by at least about 10 fold, and that reduces, maintains, or increases the luminescence that is dependent on the presence of an analyte.
    Type: Grant
    Filed: October 24, 2003
    Date of Patent: July 18, 2006
    Assignee: Promega Corporation
    Inventors: Erika Hawkins, John M. Centanni, Jacqueline Sankbeil, Keith V. Wood
  • Species specific DNA detection
    Publication number: 20040146881
    Abstract: The present invention relates to methods and compositions for the identification of species-specific material in pharmaceutical products. In particular, the present invention relates to methods for the identification of species-specific DNA in a population of a different species or following contact (e.g., growth) with cells of a different species.
    Type: Application
    Filed: August 1, 2003
    Publication date: July 29, 2004
    Applicant: OSI Pharmaceuticals. Inc.
    Inventors: Lynn Allen-Hoffmann, John M. Centanni