Patents by Inventor John M Cox

John M Cox has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250059170
    Abstract: The present disclosure relates to solid state forms of 1-((3S,5R)-1-acryloyl-5-(methoxymethyl)pyrrolidin-3-yl)-3-((1-cyclopropyl-4, 6-difluoro-1H-benzo[d]imidazol-5-yl)ethynyl)-5-(methylamino)-1H-pyrazole-4-carboxamide. Such solid state forms are useful in preparation of pharmaceutical compositions and dosage forms for the treatment of disease.
    Type: Application
    Filed: December 7, 2022
    Publication date: February 20, 2025
    Inventors: Stephen W. KALDOR, Toufike KANOUNI, Andrew PHIMISTER, Jayachandra P. REDDY, John TYHONAS, Shubham CHOPADE, Preetanshu PANDEY, Jason M. COX, Robert KANIA
  • Patent number: 12214678
    Abstract: A method and system are provided for a fastening system comprising: an electrically conductive continuous unitary structure, such as an electrically conductive stud, overmolded into an enclosure, the electrically conductive stud extending from an interior of the enclosure to an exterior of the enclosure. The fastening system may act as a structural member transferring mechanical forces away from the battery enclosure, secure the battery enclosure to a mount, aid in sealing the battery enclosure, and act as an electrical grounding path for the battery through an enclosure formed of a non-electrically conductive composite material.
    Type: Grant
    Filed: July 14, 2022
    Date of Patent: February 4, 2025
    Assignee: DANA AUTOMOTIVE SYSTEMS GROUP, LLC
    Inventors: Samuel Wesley Cox, Christopher M. Cook, John Bruzewski, Michael Kevin Nanney
  • Publication number: 20250032458
    Abstract: Provided herein are compositions and methods for the treatment of a cancer. Said compositions comprise an FGFR kinase inhibitor. Some embodiments comprise combination therapy featuring the FGFR kinase inhibitor with at least one oncology therapeutic agent.
    Type: Application
    Filed: December 7, 2022
    Publication date: January 30, 2025
    Inventors: Aleksandra FRANOVIC, Angie VASSAR, Nichol MILLER, Ken KOBAYASHI, Richard Thomas WILLIAMS, John TYHONAS, Robert KANIA, Jason M. COX, Neolito TIMPLE, Eric S. MARTIN, Eric A. MURPHY
  • Patent number: 11993000
    Abstract: The present invention relates to systems and methods for solid freeform fabrication, especially fused deposition modeling, as well as various articles made using the same, where the systems and methods utilize certain thermoplastic polyurethanes which are particularly suited for such processing. The useful thermoplastic polyurethanes are derived from (a) a polyisocyanate component, (b) a polyol component, and (c) an optional chain extender component where the resulting thermoplastic polyurethane has a crystallization temperature above 80° C. and retains more than 20% of its shear storage modulus at 100° C. relative to its shear storage modulus at 20° C.
    Type: Grant
    Filed: May 17, 2021
    Date of Patent: May 28, 2024
    Assignee: Lubrizol Advanced Materials, Inc.
    Inventors: John M. Cox, Joseph J. Vontorcik, Jr., Edward W. Ault
  • Publication number: 20210268718
    Abstract: The present invention relates to systems and methods for solid freeform fabrication, especially fused deposition modeling, as well as various articles made using the same, where the systems and methods utilize certain thermoplastic polyurethanes which are particularly suited for such processing. The useful thermoplastic polyurethanes are derived from (a) a polyisocyanate component, (b) a polyol component, and (c) an optional chain extender component where the resulting thermoplastic polyurethane has a crystallization temperature above 80° C. and retains more than 20% of its shear storage modulus at 100° C. relative to its shear storage modulus at 20° C.
    Type: Application
    Filed: May 17, 2021
    Publication date: September 2, 2021
    Applicant: Lubrizol Advanced Materials, Inc.
    Inventors: John M. Cox, Joseph J. Vontorcik, JR., Edward W. Ault
  • Publication number: 20200299530
    Abstract: The invention relates to compositions and methods for solid freeform fabrication of oral care or medical devices, components and applications, in which the composition includes a thermoplastic polyurethane which is particularly suited for such processing. The useful thermoplastic polyurethanes are derived from (a) an aromatic diisocyanate component, (b) a chain extender component, and an optional polyol component.
    Type: Application
    Filed: March 28, 2017
    Publication date: September 24, 2020
    Inventors: Jennifer Green, John M. Cox, Joseph J. Vontorcik, Jr., Barbara Morgan
  • Publication number: 20180282471
    Abstract: The invention relates to compositions and methods for solid freeform fabrication of medical devices, components and applications in which the composition includes a thermoplastic polyurethane which is particularly suited for such processing. The useful thermoplastic polyurethanes are derived from a polyisocyanate component including a first linear aliphatic diisocyate and a second aliphatic diisocyanate, a polyol component, and (c) a chain extender component.
    Type: Application
    Filed: September 29, 2016
    Publication date: October 4, 2018
    Inventors: Jennifer Green, John M. Cox, Joseph J. Vontorcik, Jr., Barbara Morgan
  • Publication number: 20180237600
    Abstract: The present invention relates to systems and methods for solid freeform fabrication, especially fused deposition modeling, as well as various articles made using the same, where the systems and methods utilize certain thermoplastic polyurethanes which are particularly suited for such processing. The useful thermoplastic polyurethanes are derived from (a) a polyisocyanate component, (b) a polyol component, and (c) an optional chain extender component where the resulting thermoplastic polyurethane has a crystallization temperature above 80° C. and retains more than 20% of its shear storage modulus at 100° C. relative to its shear storage modulus at 20° C.
    Type: Application
    Filed: April 20, 2018
    Publication date: August 23, 2018
    Inventors: John M. Cox, Joseph J. Vontorcik, JR., Edward W. Ault
  • Publication number: 20180208706
    Abstract: The invention relates to compositions and methods for solid freeform fabrication of medical devices, components and applications in which the composition includes a thermoplastic polyurethane which is particularly suited for such processing. The useful thermoplastic polyurethanes are derived from (a) an aromatic diisocyanate component, (b) a polyol component, and (c) a chain extender component where the molar ratio of (c) to (b) is at least 4.25.
    Type: Application
    Filed: July 15, 2016
    Publication date: July 26, 2018
    Inventors: Jennifer Green, John M. Cox, Joseph J. Vontorcik, JR., Barbara Morgan
  • Publication number: 20180208704
    Abstract: The invention relates to compositions and methods for solid freeform fabrication of medical devices, components and medical applications, in which the composition includes a thermoplastic polyurethane which is particularly suited for such processing. The useful thermoplastic polyurethanes are derived from (a) an aromatic diisocyanate component, (b) a polyol component, and (c) a chain extender component where the molar ratio of (c) to (b) is from 2.4 to 4.7.
    Type: Application
    Filed: July 15, 2016
    Publication date: July 26, 2018
    Inventors: Jennifer Green, John M. Cox, Joseph J. Vontorcik, JR., Barbara Morgan
  • Publication number: 20160271904
    Abstract: Traditionally, the rheological properties, including, for example, the viscosities, of two or more polymers that are to be co-extruded must be well matched in order to obtain acceptable multilayer structures. This limitation severely narrows the processing window for such co-extrusions as well as the combinations of polymers that can be used in such co-extrusions. The technology disclosed herein removes these limitations and allows for the co-extrusion of a wider variety of combinations of polymers, even when the rheological properties of the polymers to be used are significantly different, while still providing acceptable multilayer structures. Stated another way, the technology disclosed herein improves the multilayer structures that can be obtained when processing two or more polymer materials with significantly different rheological properties via layer-multiplying co-extrusion.
    Type: Application
    Filed: November 8, 2014
    Publication date: September 22, 2016
    Inventors: Joao M. Maia, Rongzhi Huang, John M. Cox
  • Patent number: 8242228
    Abstract: The present invention is a low haze thermoplastic polyurethane (TPU) prepared from a chain extender mixture that includes an acyclic diol and a mixture of 1,3- and 1,4-cyclohexanedimethanol. The TPU elastomers exhibit good optical clarity, particularly when formed into relatively thick injection molded parts.
    Type: Grant
    Filed: December 3, 2007
    Date of Patent: August 14, 2012
    Inventors: John M. Cox, Francisco Lerma, Mark F. Sonnenschein
  • Publication number: 20100109200
    Abstract: The present invention is a low haze thermoplastic polyurethane (TPU) elastomer prepared from a diol mixture that includes a polyester diol and a difunctional homopolymer of propylene oxide. The TPU elastomers of the invention solidify quickly in injection molding processes, thus reducing cycle time and manufacturing costs.
    Type: Application
    Filed: March 21, 2008
    Publication date: May 6, 2010
    Applicant: Lubrizol Advanced Materials, Inc.
    Inventors: John M. Cox, Bowdie J. Isanhart, Mark F. Sonnenschein, Rogert P. Clement
  • Publication number: 20100113733
    Abstract: The present invention is a low haze thermoplastic polyurethane (TPU) prepared from a chain extender mixture that includes an acyclic diol and a mixture of 1,3- and 1,4-cyclohexanedimethanol. The TPU elastomers exhibit good optical clarity, particularly when formed into relatively thick injection molded parts.
    Type: Application
    Filed: December 3, 2007
    Publication date: May 6, 2010
    Applicant: LUBRIZOL ADVANCED MATERIALS, INC.
    Inventors: John M. Cox, Francisco Lerma, Jr., Mark F. Sonnenschein
  • Patent number: 6291400
    Abstract: A compound of formula (I): or a salt, enamine or the like, acylate, sulphonate, carbamate or ether derivative thereof; wherein X, X1 and X2 are independently oxygen or sulphur, R1 is an optionally substituted heterocyclic or cycloalkyl group, and Y is an optionally substituted C2-C4 alkylene group which is optionally interposed by an oxygen atom, a group a group or an optionally mono-substituted nitrogen atom, wherein p is 0, 1 or 2, s is 0 or 1 and Rb is alkyl or alkoxy; provided that when X, X1 and X2 are oxygen, R1 is not pyridyl or pyrimidinyl. Processes for the preparation of these compounds and herbicidal compositions containing them are also described and claimed.
    Type: Grant
    Filed: May 27, 1999
    Date of Patent: September 18, 2001
    Assignee: Zeneca Limited
    Inventors: John E D Barton, David Cartwright, John M Cox, Glynn Mitchell, Charles G Carter, David L Lee, Francis H Walker, Frank X Woolard
  • Patent number: 6011243
    Abstract: A cabinet and control system for maintaining a food product within a predetermined temperature range for a holding period of time not exceeding a predetermined maximum time. The cabinet comprises a housing having a front panel and a passageway opening at the front panel. The passageway is capable of receiving at least two containers of the food product. A temperature element positioned in said passageway maintains the passageway within the predetermined temperature range. A processing circuit tracks the amount of time each container of food product remains within the passageway. The processing circuit provides a signal output indicating which container has been within said passageway the longest and an alarm signal when either container remains within said passageway beyond said maximum time. A display positioned on said housing proximate to said passageway receives the said signal output and indicates which container has been within the passageway the longest.
    Type: Grant
    Filed: June 24, 1997
    Date of Patent: January 4, 2000
    Inventors: Anthony W. Arnold, Steven B. Collins, Jack M. Johnson, Jeffrey S. Williams, John M. Cox, John Guthrie, Thomas A. McMillan
  • Patent number: 5958839
    Abstract: A compound of formula (I): ##STR1## or a salt, enamine or the like, acylate, sulphonate, carbamate or ether derivative thereof; wherein X, X.sup.1 and X.sup.2 are independently oxygen or sulphur, R.sup.1 is an optionally substituted heterocyclic or cycloalkyl group, and Y is an optionally substituted C.sub.2 -C.sub.4 alkylene group which is optionally interposed by an oxygen atom, a group ##STR2## a group ##STR3## or an optionally mono-substituted nitrogen atom, wherein p is 0, 1 or 2, s is 0 or 1 and R.sup.b is alkyl or alkoxy; provided that when X, X.sup.1 and X.sup.2 are oxygen, R.sup.1 is not pyridyl or pyrimidinyl. Processes for the preparation of these compounds and herbicidal compositions containing them are also described and claimed.
    Type: Grant
    Filed: February 11, 1998
    Date of Patent: September 28, 1999
    Assignee: Zeneca Litmited
    Inventors: John E. D. Barton, David Cartwright, John M Cox, Glynn Mitchell, Charles G. Carter, David L Lee, Francis H Walker, Frank X. Woolard
  • Patent number: 5744610
    Abstract: A compound of formula (I): ##STR1## or a salt, enamine or the like, acylate, sulphonate, carbamate or ether derivative thereof; wherein X, X.sup.1 and X.sup.2 are independently oxygen or sulphur, R.sup.1 is an optionally substituted heterocyclic or cycloalkyl group, and Y is an optionally substituted C.sub.2 -C.sub.4 alkylene group which is optionally interposed, by an oxygen atom, a group ##STR2## a group ##STR3## or an optionally mono-substituted nitrogen atom, wherein p is 0, 1 or 2, s is 0 or 1 and R.sup.b is alkyl or alkoxy; provided that when X, X.sup.1 and X.sup.2 are oxygen, R.sup.1 is not pyridyl or pyrimidinyl. Processes for the preparation of these compounds and herbicidal compositions containing them are also described and claimed.
    Type: Grant
    Filed: July 18, 1996
    Date of Patent: April 28, 1998
    Assignee: Zeneca Limited
    Inventors: John E. D. Barton, David Cartwright, John M. Cox, Glynn Mitchell, Charles G. Carter, David L. Lee, Francis H. Walker, Frank X. Woolard
  • Patent number: 5563115
    Abstract: A compound of formula (I): ##STR1## or a salt, enamine or the like, acylate, sulphonate, carbamate or ether derivative thereof; wherein X, X.sup.1 and X.sup.2 are independently oxygen or sulphur, R.sup.1 is an optionally substituted heterocyclic or cycloalkyl group, and Y is an optionally substituted C.sub.2 -C.sub.4 alkylene group which is optionally interposed by an oxygen atom, a group ##STR2## a group ##STR3## or an optionally mono-substituted nitrogen atom, wherein p is 0, 1 or 2, s is 0 or 1 and R.sup.b is alkyl or alkoxy; provided that when X, X.sup.1 and X.sup.2 are oxygen, R.sup.1 is not pyridyl or pyrimidinyl. Processes for the preparation of these compounds and herbicidal compositions containing them are also described and claimed.
    Type: Grant
    Filed: May 30, 1995
    Date of Patent: October 8, 1996
    Assignee: Zeneca Limited
    Inventors: John E. D. Barton, David Cartwright, John M. Cox, Glynn Mitchell, Charles G. Carter, David L. Lee, Francis H. Walker, Frank X. Woolard
  • Patent number: 5426091
    Abstract: A compound of formula (I): ##STR1## or a salt, enamine or the like, acylate, sulphonate, carbamate or ether derivative thereof; wherein X, X.sup.1 and X.sup.2 are independently oxygen or sulphur, R.sup.1 is an optionally substituted heterocyclic or cycloalkyl group, and Y is an optionally substituted C.sub.2 -C.sub.4 alkylene group which is optionally interposed by an oxygen atom, a group ##STR2## or an optionally mono-substituted nitrogen atom, wherein p is 0, 1 or 2, s is 0 or 1 and R.sup.b is alkyl or alkoxy; provided that when X, X.sup.1 and X.sup.2 are oxygen, R.sup.1 is not pyridyl or pyrimidinyl. Processes for the preparation of these compounds and herbicidal compositions containing them are also described and claimed.
    Type: Grant
    Filed: August 4, 1993
    Date of Patent: June 20, 1995
    Assignee: Zeneca Limited
    Inventors: John E. D. Barton, David Cartwright, John M. Cox, Glynn Mitchell, Charles G. Carter, David L. Lee, Francis H. Walker, Frank X. Woolard