Abstract: Methods of braiding using a braiding mechanism are described. The braiding mechanism includes a disc defining a plane and a circumferential edge, a mandrel extending from a center of the disc that is adapted to hold a plurality of filaments extending radially from the mandrel toward the circumferential edge of the disc, a plurality of catch mechanisms positioned circumferentially around the edge of the disc, a plurality of actuators adapted to move the plurality of catch mechanisms in a substantially radial direction relative to the circumferential edge of the disc, and a plurality of filaments extending radially from the mandrel towards circumferential edge of the disc. A middle portion of each filament of the plurality of filaments contacts an end of the mandrel.

Abstract: Each of one or more unknown compounds are separated from a sample over a separation time period. Separated compounds are ionized, producing one or more compound precursor ions for each of the unknown compounds and a plurality of background precursor ions. A precursor ion mass spectrum is measured for the combined compound and background precursor ions at each time step of a plurality of time steps spread across the separation time period, producing a plurality of precursor ion mass spectra. One or more background precursor ions are selected from the plurality of precursor ion mass spectra that have a resolving power in a range below a threshold expected resolving power. A separation time is detected for an unknown compound when a decrease in an intensity measurement of the selected background precursor ions over a time period exceeds a threshold decrease in intensity with respect to time.

Abstract: Provided herein are inhibitors of MET receptor tyrosine kinase, pharmaceutical compositions comprising said inhibitory compounds, and methods for using said MET kinase inhibitory compounds for the treatment of disease.

Abstract: The present invention relates to systems and methods for solid freeform fabrication, especially fused deposition modeling, as well as various articles made using the same, where the systems and methods utilize certain thermoplastic polyurethanes which are particularly suited for such processing. The useful thermoplastic polyurethanes are derived from (a) a polyisocyanate component, (b) a polyol component, and (c) an optional chain extender component where the resulting thermoplastic polyurethane has a crystallization temperature above 80° C. and retains more than 20% of its shear storage modulus at 100° C. relative to its shear storage modulus at 20° C.

Abstract: The invention relates to compositions and methods for solid freeform fabrication of oral care or medical devices, components and applications, in which the composition includes a thermoplastic polyurethane which is particularly suited for such processing. The useful thermoplastic polyurethanes are derived from (a) an aromatic diisocyanate component, (b) a chain extender component, and an optional polyol component.

Abstract: The invention relates to compositions and methods for solid freeform fabrication of medical devices, components and applications in which the composition includes a thermoplastic polyurethane which is particularly suited for such processing. The useful thermoplastic polyurethanes are derived from a polyisocyanate component including a first linear aliphatic diisocyate and a second aliphatic diisocyanate, a polyol component, and (c) a chain extender component.

Abstract: The present invention relates to systems and methods for solid freeform fabrication, especially fused deposition modeling, as well as various articles made using the same, where the systems and methods utilize certain thermoplastic polyurethanes which are particularly suited for such processing. The useful thermoplastic polyurethanes are derived from (a) a polyisocyanate component, (b) a polyol component, and (c) an optional chain extender component where the resulting thermoplastic polyurethane has a crystallization temperature above 80° C. and retains more than 20% of its shear storage modulus at 100° C. relative to its shear storage modulus at 20° C.

Abstract: The invention relates to compositions and methods for solid freeform fabrication of medical devices, components and medical applications, in which the composition includes a thermoplastic polyurethane which is particularly suited for such processing. The useful thermoplastic polyurethanes are derived from (a) an aromatic diisocyanate component, (b) a polyol component, and (c) a chain extender component where the molar ratio of (c) to (b) is from 2.4 to 4.7.

Abstract: The invention relates to compositions and methods for solid freeform fabrication of medical devices, components and applications in which the composition includes a thermoplastic polyurethane which is particularly suited for such processing. The useful thermoplastic polyurethanes are derived from (a) an aromatic diisocyanate component, (b) a polyol component, and (c) a chain extender component where the molar ratio of (c) to (b) is at least 4.25.

Abstract: Traditionally, the rheological properties, including, for example, the viscosities, of two or more polymers that are to be co-extruded must be well matched in order to obtain acceptable multilayer structures. This limitation severely narrows the processing window for such co-extrusions as well as the combinations of polymers that can be used in such co-extrusions. The technology disclosed herein removes these limitations and allows for the co-extrusion of a wider variety of combinations of polymers, even when the rheological properties of the polymers to be used are significantly different, while still providing acceptable multilayer structures. Stated another way, the technology disclosed herein improves the multilayer structures that can be obtained when processing two or more polymer materials with significantly different rheological properties via layer-multiplying co-extrusion.

Abstract: The present invention is a low haze thermoplastic polyurethane (TPU) prepared from a chain extender mixture that includes an acyclic diol and a mixture of 1,3- and 1,4-cyclohexanedimethanol. The TPU elastomers exhibit good optical clarity, particularly when formed into relatively thick injection molded parts.

Abstract: The present invention is a low haze thermoplastic polyurethane (TPU) elastomer prepared from a diol mixture that includes a polyester diol and a difunctional homopolymer of propylene oxide. The TPU elastomers of the invention solidify quickly in injection molding processes, thus reducing cycle time and manufacturing costs.

Abstract: The present invention is a low haze thermoplastic polyurethane (TPU) prepared from a chain extender mixture that includes an acyclic diol and a mixture of 1,3- and 1,4-cyclohexanedimethanol. The TPU elastomers exhibit good optical clarity, particularly when formed into relatively thick injection molded parts.

Abstract: A compound of formula (I): or a salt, enamine or the like, acylate, sulphonate, carbamate or ether derivative thereof; wherein X, X1 and X2 are independently oxygen or sulphur, R1 is an optionally substituted heterocyclic or cycloalkyl group, and Y is an optionally substituted C2-C4 alkylene group which is optionally interposed by an oxygen atom, a group a group or an optionally mono-substituted nitrogen atom, wherein p is 0, 1 or 2, s is 0 or 1 and Rb is alkyl or alkoxy; provided that when X, X1 and X2 are oxygen, R1 is not pyridyl or pyrimidinyl. Processes for the preparation of these compounds and herbicidal compositions containing them are also described and claimed.

Abstract: A cabinet and control system for maintaining a food product within a predetermined temperature range for a holding period of time not exceeding a predetermined maximum time. The cabinet comprises a housing having a front panel and a passageway opening at the front panel. The passageway is capable of receiving at least two containers of the food product. A temperature element positioned in said passageway maintains the passageway within the predetermined temperature range. A processing circuit tracks the amount of time each container of food product remains within the passageway. The processing circuit provides a signal output indicating which container has been within said passageway the longest and an alarm signal when either container remains within said passageway beyond said maximum time. A display positioned on said housing proximate to said passageway receives the said signal output and indicates which container has been within the passageway the longest.

Abstract: A compound of formula (I): ##STR1## or a salt, enamine or the like, acylate, sulphonate, carbamate or ether derivative thereof; wherein X, X.sup.1 and X.sup.2 are independently oxygen or sulphur, R.sup.1 is an optionally substituted heterocyclic or cycloalkyl group, and Y is an optionally substituted C.sub.2 -C.sub.4 alkylene group which is optionally interposed by an oxygen atom, a group ##STR2## a group ##STR3## or an optionally mono-substituted nitrogen atom, wherein p is 0, 1 or 2, s is 0 or 1 and R.sup.b is alkyl or alkoxy; provided that when X, X.sup.1 and X.sup.2 are oxygen, R.sup.1 is not pyridyl or pyrimidinyl. Processes for the preparation of these compounds and herbicidal compositions containing them are also described and claimed.

Abstract: A compound of formula (I): ##STR1## or a salt, enamine or the like, acylate, sulphonate, carbamate or ether derivative thereof; wherein X, X.sup.1 and X.sup.2 are independently oxygen or sulphur, R.sup.1 is an optionally substituted heterocyclic or cycloalkyl group, and Y is an optionally substituted C.sub.2 -C.sub.4 alkylene group which is optionally interposed, by an oxygen atom, a group ##STR2## a group ##STR3## or an optionally mono-substituted nitrogen atom, wherein p is 0, 1 or 2, s is 0 or 1 and R.sup.b is alkyl or alkoxy; provided that when X, X.sup.1 and X.sup.2 are oxygen, R.sup.1 is not pyridyl or pyrimidinyl. Processes for the preparation of these compounds and herbicidal compositions containing them are also described and claimed.

Abstract: A compound of formula (I): ##STR1## or a salt, enamine or the like, acylate, sulphonate, carbamate or ether derivative thereof; wherein X, X.sup.1 and X.sup.2 are independently oxygen or sulphur, R.sup.1 is an optionally substituted heterocyclic or cycloalkyl group, and Y is an optionally substituted C.sub.2 -C.sub.4 alkylene group which is optionally interposed by an oxygen atom, a group ##STR2## a group ##STR3## or an optionally mono-substituted nitrogen atom, wherein p is 0, 1 or 2, s is 0 or 1 and R.sup.b is alkyl or alkoxy; provided that when X, X.sup.1 and X.sup.2 are oxygen, R.sup.1 is not pyridyl or pyrimidinyl. Processes for the preparation of these compounds and herbicidal compositions containing them are also described and claimed.

Abstract: A compound of formula (I): ##STR1## or a salt, enamine or the like, acylate, sulphonate, carbamate or ether derivative thereof; wherein X, X.sup.1 and X.sup.2 are independently oxygen or sulphur, R.sup.1 is an optionally substituted heterocyclic or cycloalkyl group, and Y is an optionally substituted C.sub.2 -C.sub.4 alkylene group which is optionally interposed by an oxygen atom, a group ##STR2## or an optionally mono-substituted nitrogen atom, wherein p is 0, 1 or 2, s is 0 or 1 and R.sup.b is alkyl or alkoxy; provided that when X, X.sup.1 and X.sup.2 are oxygen, R.sup.1 is not pyridyl or pyrimidinyl. Processes for the preparation of these compounds and herbicidal compositions containing them are also described and claimed.

Abstract: A herbicidal compound of formula (I) ##STR1## or a salt, tautomer or cyclic derivative thereof; where R.sup.1 and R.sup.2 are hydrogen and A is an optionally substituted saturated or unsaturated chain or ring of three carbon atoms.Methods for preparing these compounds, intermediates used in the preparation and herbicidal compositions containing them are also described and claimed.