Patents by Inventor John M. Doyle

John M. Doyle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11960456
    Abstract: A graph-based clinical concept mapping algorithm maps ICD-9 (International Classification of Disease, Revision 9) and ICD-10 (International Classification of Disease, Revision 10) codes to unified Systematized Nomenclature of Medicine (SNOMED) clinical concepts to normalize longitudinal healthcare data to thereby improve tracking and the use of such data for research and commercial purposes. The graph-based clinical concept mapping algorithm advantageously combines a novel graph-based search algorithm and natural language processing to map orphan ICD codes (those without equivalents across codebases) by finding optimally relevant shared SNOMED concepts. The graph-based clinical concept mapping algorithm is further advantageously utilized to group ICD-9/10 codes into higher order, more prevalent SNOMED concepts to support clinical interpretation.
    Type: Grant
    Filed: February 25, 2020
    Date of Patent: April 16, 2024
    Assignee: IQVIA Inc.
    Inventors: Shaun Gupta, Frederik B. C. Dieleman, Daniel Homola, Adam Webber, Orla M. Doyle, Nadejda Leavitt, John Rigg, Patrick Long, Rabe'e Cheheltani
  • Patent number: 9909998
    Abstract: An apparatus for spectroscopy of a gas mixture is described. Such an apparatus includes a gas mixing system configured to mix a hot analyte gas that includes at least one analyte species in a gas phase into a cold buffer gas, thereby forming a supersaturated mixture to be provided for spectroscopic analysis.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: March 6, 2018
    Assignee: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: David S. Patterson, John M. Doyle
  • Patent number: 9857315
    Abstract: A spectrometer includes: (1) a housing defining a volume into which an analyte gas is introduced, the analyte gas including a chiral component; (2) a microwave generator coupled to the housing and configured to apply a microwave pulse to the analyte gas, the microwave pulse being polarized along a first direction; (3) an electric field generator coupled to the housing and configured to apply a switched electric field to the analyte gas, the electric field being oriented along a second direction different from the first direction; (4) a phase-sensitive microwave detector coupled to the housing and configured to detect an induced microwave emitted by the analyte gas, the induced microwave being polarized along a third direction different from the first direction and the second direction; and (5) an analyzer coupled to the phase-sensitive microwave detector and configured to detect an enantiomer of the chiral component based on a phase of the induced microwave.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: January 2, 2018
    Assignee: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: David S. Patterson, John M. Doyle
  • Publication number: 20150177164
    Abstract: A spectrometer includes: (1) a housing defining a volume into which an analyte gas is introduced, the analyte gas including a chiral component; (2) a microwave generator coupled to the housing and configured to apply a microwave pulse to the analyte gas, the microwave pulse being polarized along a first direction; (3) an electric field generator coupled to the housing and configured to apply a switched electric field to the analyte gas, the electric field being oriented along a second direction different from the first direction; (4) a phase-sensitive microwave detector coupled to the housing and configured to detect an induced microwave emitted by the analyte gas, the induced microwave being polarized along a third direction different from the first direction and the second direction; and (5) an analyzer coupled to the phase-sensitive microwave detector and configured to detect an enantiomer of the chiral component based on a phase of the induced microwave.
    Type: Application
    Filed: March 14, 2013
    Publication date: June 25, 2015
    Inventors: David S. Patterson, John M. Doyle
  • Publication number: 20150077137
    Abstract: An apparatus for spectroscopy of a gas mixture is described. Such an apparatus includes a gas mixing system configured to mix a hot analyte gas that includes at least one analyte species in a gas phase into a cold buffer gas, thereby forming a supersaturated mixture to be provided for spectroscopic analysis.
    Type: Application
    Filed: March 13, 2013
    Publication date: March 19, 2015
    Inventors: David S. Patterson, John M. Doyle
  • Patent number: 8907286
    Abstract: A system includes a cold cell tube configured to receive a mixture of a target gas and a buffer gas to cool the target gas to a temperature at which a partial pressure of the target gas is greater than the saturated vapor pressure of the target gas while maintaining at least a portion of the target gas in the gas phase. The system also includes a spectroscopic module configured to detect the cooled target gas in the cold cell tube; and an analysis module configured to determine a characteristic of the target gas based on the results of the detecting.
    Type: Grant
    Filed: April 12, 2011
    Date of Patent: December 9, 2014
    Assignee: President and Fellows of Harvard College
    Inventors: John M. Doyle, David S. Patterson
  • Publication number: 20130107244
    Abstract: A system includes a cold cell tube configured to receive a mixture of a target gas and a buffer gas to cool the target gas to a temperature at which a partial pressure of the target gas is greater than the saturated vapor pressure of the target gas while maintaining at least a portion of the target gas in the gas phase. The system also includes a spectroscopic module configured to detect the cooled target gas in the cold cell tube; and an analysis module configured to determine a characteristic of the target gas based on the results of the detecting.
    Type: Application
    Filed: April 12, 2011
    Publication date: May 2, 2013
    Applicant: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: John M. Doyle, David S. Patterson
  • Patent number: 4249172
    Abstract: A logic control system for a video display terminal is disclosed for accommodating vertically and horizontally varying entry points to a video memory to acquire first character bytes of rows of video information for display on a CRT screen. Dynamically changeable display page snapshots of the video memory, and the formation of display pages from randomly located rows of video information within the video memory are thereby provided.
    Type: Grant
    Filed: September 4, 1979
    Date of Patent: February 3, 1981
    Assignee: Honeywell Information Systems Inc.
    Inventors: Richard R. Watkins, C. Steven Briggs, John M. Doyle, Jr.