Abstract: Systems and methods for modeling and detecting white blood cell population dynamic for diagnosis and treatment, e.g., of acute coronary syndrome or leukocytosis.

Abstract: A method includes receiving data representing a first complete blood count (CBC) measured from a first sample of red blood cells (RBCs) from a subject and data representing a second CBC measured from a second sample of RBCs from the subject, each of the first and second CBCs including a volume and a hemoglobin content of each of the RBCs in the respective sample, the first and second samples being different samples corresponding to different times. Parameters representing RBC population dynamics for the subject are calculated based on the volume and the hemoglobin content for the RBCs in each of the first and second samples and a time between the first and second samples. A pathophysiological state of the subject is determined based on the one or more parameters representing the RBC population dynamics.

Abstract: Systems and methods for modeling and detecting white blood cell population dynamic for diagnosis and treatment, e.g., of acute coronary syndrome or leukocytosis.

Abstract: Methods for identifying patients with anemia, distinguishing thalassemia-trait anemia from iron-deficiency anemia, and identifying pre-anemic patients several weeks before anemia becomes clinically detectable. Also, methods for detecting blood doping in athletes and for optimizing therapy with erythropoiesis stimulating agents or iron supplementation. Computer-readable storage devices and systems, e.g., for use in the described methods.

Abstract: Systems and methods for modeling and detecting white blood cell population dynamic for diagnosis and treatment, e.g., of acute coronary syndrome or leukocytosis.

Abstract: A method includes estimating a value of a parameter indicative of an age or lifespan of a population of red blood cells of a subject, estimating a value of average glucose (AG) of the subject based on (i) the value of the parameter and (ii) a value indicative of an amount of glycated hemoglobin (HbA1c) of the subject, and providing information for treatment or diagnosis of a hyperglycemia condition of the subject based on the estimated value of AG.

Abstract: A method includes estimating a value of a parameter indicative of an age or lifespan of a population of red blood cells of a subject, estimating a value of average glucose (AG) of the subject based on (i) the value of the parameter and (ii) a value indicative of an amount of glycated hemoglobin (HbA1c) of the subject, and providing information for treatment or diagnosis of a hyperglycemia condition of the subject based on the estimated value of AG.

Abstract: Systems and methods for modeling and detecting white blood cell population dynamic for diagnosis and treatment, e.g., of acute coronary syndrome or leukocytosis.

Abstract: A method includes estimating a value of a parameter indicative of an age or lifespan of a population of red blood cells of a subject, estimating a value of average glucose (AG) of the subject based on (i) the value of the parameter and (ii) a value indicative of an amount of glycated hemoglobin (HbA1c) of the subject, and providing information for treatment or diagnosis of a hyperglycemia condition of the subject based on the estimated value of AG.

Abstract: Methods for identifying patients with anemia, distinguishing thalassemia-trait anemia from iron-deficiency anemia, and identifying pre-anemic patients several weeks before anemia becomes clinically detectable. Also, methods for detecting blood doping in athletes and for optimizing therapy with erythropoiesis stimulating agents or iron supplementation. Computer-readable storage devices and systems, e.g., for use in the described methods.

Abstract: Methods for identifying patients with anemia, distinguishing thalassemia-trait anemia from iron-deficiency anemia, and identifying pre-anemic patients several weeks before anemia becomes clinically detectable. Also, methods for detecting blood doping in athletes and for optimizing therapy with erythropoiesis stimulating agents or iron supplementation. Computer-readable storage devices and systems, e.g., for use in the described methods.

Abstract: A method for evaluating a risk of a morbidity associated with elevated red blood cell (RBC) volume variation (RDW) includes measuring, using a hematology analyzer, a complete blood count (CBC) of a blood sample including a population of RBCs from a subject. In some embodiments, the method includes estimating a normalized clearance volume of the population of the RBCs based on the CBC. In some embodiments, the method includes comparing the normalized clearance volume to a reference value. In some embodiments, the method includes determining a risk level for the patient to develop the morbidity associated with elevated RDW within a specified time period. In some embodiments, the risk level is high if the normalized clearance volume is below the reference value, and the risk level is low if the normalized clearance volume is above the reference value. In some embodiments, the method further includes selecting the patient for diagnostic workup for the morbidity if the risk level is high.

Abstract: The invention comprises systems, methods and computer programs for information retrieval using content algebra. In an embodiment, the invention comprises (i) receiving a first plurality of search results returned by the search engine in response to a first search query, (ii) generating a first plurality of search result vectors, wherein each of the first plurality of search result vectors may be generated based on a corresponding search result from among the first plurality of search results and may comprise data describing the corresponding search result, (iii) generating a first search result image vector based on data from the first plurality of search result vectors, and (iv) displaying information representative of the first plurality of search results on a display device such that visual configuration of the displayed information may be based on data within the first search result image vector.

Abstract: In one embodiment, a method of transmitting a directed query from a client device that stores private data elements includes determining relationships between elements of the private data, where each of the relationships associates two or more elements of the private data. The method may further include receiving a query related to a target element of the private data, where the query requests data related to the element that is not present in the private data. The method may further include storing the query in electronic memory. The method may further include determining a recipient for the query based on the relationships associated with the target element of the query. The method may further include electronically transmitting the query to the recipient.

Abstract: Methods for identifying patients with anemia, distinguishing thalassemia-trait anemia from iron-deficiency anemia, and identifying pre-anemic patients several weeks before anemia becomes clinically detectable. Also, methods for detecting blood doping in athletes and for optimizing therapy with erythropoiesis stimulating agents or iron supplementation. Computer-readable storage devices and systems, e.g., for use in the described methods.

Abstract: A method for creating composite droplets for use in an ink jet system includes a first fluid (1) brought into contact with a second fluid within a set of channels (5,14). The interface between the fluids is characterized by an interfacial tension. The first fluid forms spaced droplets (8) within the second fluid, the composite of the first and second fluids passing through an orifice (6) to form a jet (9).

Abstract: An inkjet printing system comprising a plurality of static inkjet printing units each comprising at least one inkjet printing head; an ink-receiving element comprising a poorly-absorbing or impermeable substrate; an aqueous inkjet composition which comprises a polymeric compound comprising discrete particles responsive to an external stimulus, and a functional material, which may be incorporated as part of the polymeric particles, the composition having a first rheological state and a different second rheological state in response to a stimulated change in conditions, the first state being associated with a first lower viscosity of the composition, wherein the particles have a first lower volume, and the second state being associated with a second higher viscosity of the composition, wherein the particles have a second higher volume, and of drying the aqueous ink composition only positioned downstream of the plurality of the printing units.

Abstract: The invention provides an aqueous inkjet ink composition comprises a polymeric compound comprising discrete particles responsive to an external stimulus, and a functional material, wherein the functional material may be incorporated as part of the polymeric particles, the particles causing the composition to have a first rheological state and a different second rheological state in response to a stimulated change in conditions, the first rheological state being associated with a first lower viscosity of the composition, wherein the particles have a first lower volume, enabling the composition to pass through an inkjet printhead orifice and the second rheological state being associated with a second higher viscosity of the composition, wherein the particles have a second higher volume, enabling immobilisation of droplets of the composition on a substrate.

Abstract: The invention relates to a method of making a planographic printing plate comprising a substrate having thereon one or more layers of a radiation-sensitive metal oxide, sulfide or nitride and excluding an organic hydrophobic material or a binder within or above a radiation-sensitive layer, the method comprising depositing the one or more layers of the radiation-sensitive metal oxide, sulfide or nitride by vapor deposition and exposing the one or more layers without that exposure causing ablative effect. Preferably the compound, and in particular a metal oxide, such as titanium dioxide, is deposited by atomic layer deposition at atmospheric pressure and at a temperature of from 20° C. to 300° C. at a layer thickness of less than 100 nm. The substrate can be any planar material, preferably with the potential to be flexible and with a surface that can be roughened or textured.

Abstract: A method of creating a patterned coated layer on a substrate comprises the steps of applying a pattern on the substrate by an additive process using a first material, depositing a second material by vapour deposition over the whole substrate area and mechanically removing the pattern of first material from the substrate, leaving the inverse pattern of the second material.