Patents by Inventor John M. Keith

John M. Keith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SUBSTITUTED PYRIDYL AMIDE COMPOUNDS AS MODULATORS OF THE HISTAMINE H3 RECEPTOR
    Publication number: 20100267701
    Abstract: Certain substituted pyridyl amide compounds are histamine H3 receptor modulators useful in the treatment of histamine H3 receptor-mediated diseases.
    Type: Application
    Filed: July 1, 2010
    Publication date: October 21, 2010
    Inventors: John M. Keith, Michael A. Letavic, Kiev S. Ly, Neelakandha S. Mani, John E. Mills, Chennagiri R. Pandit, Frank J. Villani, Hua Zhong
  • BUTYL AND BUTYNYL BENZYL AMINE COMPOUNDS
    Publication number: 20100256122
    Abstract: Certain substituted butyl and butynyl benzyl amine compounds are histamine H3 receptor and/or serotonin transporter modulators useful in the treatment of histamine H3 receptor- and/or serotonin-mediated diseases.
    Type: Application
    Filed: June 22, 2010
    Publication date: October 7, 2010
    Inventors: John M. Keith, Michael A. Letavic, Emily M. Stocking
  • HEXAHYDRO-PYRROLO-ISOQUINOLINE COMPOUNDS
    Publication number: 20100240648
    Abstract: Certain hexahydro-pyrrolo-isoquinoline compounds are histamine H3 receptor and serotonin transporter modulators useful in the treatment of histamine H3 receptor- and serotonin-mediated diseases.
    Type: Application
    Filed: June 2, 2010
    Publication date: September 23, 2010
    Inventors: Richard Apodaca, Ann J. Barbier, Nicholas I. Carruthers, Leslie A. Gomez, John M. Keith, Timothy W. Lovenberg, Ronald L. Wolin
  • Butyl and butynyl benzyl amine compounds
    Patent number: 7767666
    Abstract: Certain substituted butyl and butynyl benzyl amine compounds are histamine H3 receptor and/or serotonin transporter modulators useful in the treatment of histamine H3 receptor- and/or serotonin-mediated diseases.
    Type: Grant
    Filed: June 21, 2007
    Date of Patent: August 3, 2010
    Assignee: Janssen Pharmaceutica NV
    Inventors: John M. Keith, Michael A. Letavic, Emily M. Stocking
  • Hexahydro-pyrrolo-isoquinoline compounds
    Patent number: 7754882
    Abstract: Certain hexahydro-pyrrolo-isoquinoline compounds are histamine H3 receptor and serotonin transporter modulators useful in the treatment of histamine H3 receptor- and serotonin-mediated diseases.
    Type: Grant
    Filed: June 16, 2006
    Date of Patent: July 13, 2010
    Assignee: Janssen Pharmaceutica NV
    Inventors: Richard Apodaca, Ann J. Barbier, Nicholas I. Carruthers, Leslie A. Gomez, John M. Keith, Timothy W. Lovenberg, Ronald L. Wolin
  • Aryl - Hydroxyethylamino - Pyrimidines and Triazines as Modulators of Fatty Acid amide Hydrolase
    Publication number: 20090264429
    Abstract: Certain aryl-hydroxyethylamino-pyrimidine and triazine compounds are described, which are useful as FAAH inhibitors. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by fatty acid amide hydrolase (FAAH) activity, such as anxiety, pain, inflammation, sleep disorders, eating disorders, energy metabolism disorders, and movement disorders (e.g., multiple sclerosis). Methods of synthesizing such compounds are also disclosed.
    Type: Application
    Filed: February 18, 2009
    Publication date: October 22, 2009
    Inventors: Richard Apodaca, J. Guy Breitenbucher, Alison L. Chambers, Xiaohu Deng, Natalie A. Hawryluk, John M. Keith, Neelakandha S. Mani, Jeffrey E. Merit, Joan M. Pierce, Mark Seierstad, Wei Xiao
  • SUBSTITUTED BENZYL AMINE COMPOUNDS
    Publication number: 20090137562
    Abstract: Certain substituted benzyl amine compounds are histamine H3 receptor and/or serotonin transporter modulators useful in the treatment of histamine H3 receptor- and/or serotonin-mediated diseases.
    Type: Application
    Filed: December 9, 2008
    Publication date: May 28, 2009
    Inventors: Brett Allison, Michael P. Curtis, Cheryl A. Grice, John M. Keith, Michael A. Letavic, Jennifer M.B. Miller, Emily M. Stocking
  • HETEROARYL-SUBSTITUTED UREA MODULATORS OF FATTY ACID AMIDE HYDROLASE
    Publication number: 20090062294
    Abstract: Certain heteroaryl-substituted piperidinyl and piperazinyl urea compounds are described, which are useful as FAAH inhibitors. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by fatty acid amide hydrolase (FAAH) activity, such as anxiety, pain, inflammation, sleep disorders, eating disorders, insulin resistance, diabetes, osteoporosis, and movement disorders (e.g., multiple sclerosis).
    Type: Application
    Filed: May 23, 2008
    Publication date: March 5, 2009
    Inventors: Richard Apodaca, J. Guy Breitenbucher, Natalie A. Hawryluk, William M. Jones, John M. Keith, Jeffrey E. Merit, Mark S. Tichenor, Amy K. Timmons
  • Substituted benzyl amine compounds
    Patent number: 7479493
    Abstract: Certain substituted benzyl amine compounds are histamine H3 receptor and/or serotonin transporter modulators useful in the treatment of histamine H3 receptor- and/or serotonin-mediated diseases.
    Type: Grant
    Filed: June 21, 2007
    Date of Patent: January 20, 2009
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Brett Allison, Michael P. Curtis, Cheryl A. Grice, John M. Keith, Michael A. Letavic, Jennifer M. B. Miller, Emily M. Stocking
  • DIARYL-SUBSTITUTED TETRAHYDROISOQUINOLINES AS HISTAMINE H3 RECEPTOR AND SEROTONIN TRANSPORTER MODULATORS
    Publication number: 20080318952
    Abstract: Certain diaryl-substituted tetrahydroisoquinoline compounds are histamine H3 receptor and/or serotonin transporter modulators useful in the treatment of histamine H3 receptor- and/or serotonin-mediated diseases.
    Type: Application
    Filed: May 13, 2008
    Publication date: December 25, 2008
    Inventor: John M. Keith
  • Naphthyridine compounds
    Patent number: 7417054
    Abstract: Certain naphthyridine compounds are histamine H3 receptor and serotonin transporter modulators useful in the treatment of histamine H3 receptor- and serotonin-mediated diseases.
    Type: Grant
    Filed: June 16, 2006
    Date of Patent: August 26, 2008
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Nicholas I. Carruthers, John M. Keith, Michael A. Letavic, Chandravadan R. Shah
  • SUBSTITUTED PHENYL PROPYL AMINES AS HISTAMINE H3 RECEPTOR AND SEROTONIN TRANSPORTER MODULATORS
    Publication number: 20080139564
    Abstract: Certain substituted phenyl propyl amine compounds are histamine H3 receptor and/or serotonin transporter modulators useful in the treatment of histamine H3 receptor- and/or serotonin-mediated diseases.
    Type: Application
    Filed: November 14, 2007
    Publication date: June 12, 2008
    Inventors: John M. Keith, Jennifer M.B. Miller, Emily M. Stocking
  • SUBSTITUTED AMINOMETHYL BENZAMIDE COMPOUNDS
    Publication number: 20080045508
    Abstract: Certain substituted aminomethyl benzamide compounds are histamine H3 receptor and/or serotonin transporter modulators useful in the treatment of histamine H3 receptor- and/or serotonin-mediated diseases.
    Type: Application
    Filed: June 21, 2007
    Publication date: February 21, 2008
    Inventors: Brett Allison, Nicholas I. Carruthers, Michael P. Curtis, John M. Keith, Michael A. Letavic, Emily M. Stocking
  • SUBSTITUTED BENZYL AMINE COMPOUNDS
    Publication number: 20080045509
    Abstract: Certain substituted benzyl amine compounds are histamine H3 receptor and/or serotonin transporter modulators useful in the treatment of histamine H3 receptor- and/or serotonin-mediated diseases.
    Type: Application
    Filed: June 21, 2007
    Publication date: February 21, 2008
    Inventors: Brett Allison, Michael P. Curtis, Cheryl A. Grice, John M. Keith, Michael A. Letavic, Jennifer M. B. Miller, Emily M. Stocking
  • BUTYL AND BUTYNYL BENZYL AMINE COMPOUNDS
    Publication number: 20080004258
    Abstract: Certain substituted butyl and butynyl benzyl amine compounds are histamine H3 receptor and/or serotonin transporter modulators useful in the treatment of histamine H3 receptor- and/or serotonin-mediated diseases.
    Type: Application
    Filed: June 21, 2007
    Publication date: January 3, 2008
    Inventors: John M. Keith, Michael A. Letavic, Emily M. Stocking
  • SUBSTITUTED PYRIDYL AMIDE COMPOUNDS AS MODULATORS OF THE HISTAMINE H3 RECEPTOR
    Publication number: 20070281923
    Abstract: Certain substituted pyridyl amide compounds are histamine H3 receptor modulators useful in the treatment of histamine H3 receptor-mediated diseases.
    Type: Application
    Filed: May 25, 2007
    Publication date: December 6, 2007
    Inventors: John M. Keith, Michael A. Letavic, Kiev S. Ly, Neelakandha S. Mani, John E. Mills, Chennagiri R. Pandit, Frank J. Villani, Hua Zhong
  • Adaptive digital video compression system
    Patent number: 5225904
    Abstract: A full motion color digital video signal is compressed, formatted for transmission, recorded on compact disc media and decoded at conventional video frame rates. During compression, regions of a frame are individually analyzed to select optimum fill coding methods specific to each region. Region decoding time estimates are made to optimize compression thresholds. Region descriptive codes conveying the size and locations of the regions are grouped together in a first segment of a data stream. Region fill codes conveying pixel amplitude indications for the regions are grouped together according to fill code type and placed in other segments of the data stream. The data stream segments are individually variable length coded according to their respective statistical distributions and formatted to form data frames.
    Type: Grant
    Filed: December 4, 1991
    Date of Patent: July 6, 1993
    Assignee: Intel Corporation
    Inventors: Stuart J. Golin, Allen H. Simon, Brian Astle, John M. Keith
  • Processor with hierarchal memory and using meta-instructions for software control of loading, unloading and execution of machine instructions stored in the cache
    Patent number: 5187793
    Abstract: An instruction caching system comprises meta-instructions which are contained within the program being executed. A meta-machine, which is a small segment of software, executes the meta-instructions and passes control to the processor itself at appropriate times to execute blocks of instructions from the instruction cache.
    Type: Grant
    Filed: January 9, 1989
    Date of Patent: February 16, 1993
    Assignee: Intel Corporation
    Inventors: John M. Keith, Allen H. Simon, David L. Sprague, Douglas F. Dixon, Judith A. Goldstein
  • Adaptive video compression system
    Patent number: 5079630
    Abstract: A full motion color digital video signal is compressed, formatted for transmission, recorded on compact disc media and decoded at conventional video frame rates. During compression, regions of a frame are individually analyzed to select optimum fill coding methods specific to each region. Region decoding time estimates are made to optimize compression thresholds. Region descriptive codes conveying the size and locations of the regions are grouped together in a first segment of a data stream. Region fill codes conveying pixel amplitude indications for the regions are grouped together according to fill code type and placed in other segments of the data stream. The data stream segments are individually variable length coded according to their respective statistical distributions and formatted to form data frames.
    Type: Grant
    Filed: September 15, 1989
    Date of Patent: January 7, 1992
    Assignee: Intel Corporation
    Inventors: Stuart J. Golin, Allen H. Simon, Brian Astle, John M. Keith
  • Digital video formatting and transmission system and method
    Patent number: 4918523
    Abstract: A full motion color digital video signal is compressed, formatted for transmission, recorded on compact disc media and decoded at conventional video frame rates. During compression, regions of a frame are individually analyzed to select optimum fill coding methods specific to each region. Region decoding time estimates are made to optimize compression thresholds. Region descriptive codes conveying the size and locations of the regions are grouped together in a first segment of a data stream. Region fill codes conveying pixel amplitude indications for the regions are grouped together according to fill code type and placed in other segments of the data stream. The data stream segments are individually variable length coded according to their respective statistical distributions and formatted to form data frames.
    Type: Grant
    Filed: October 5, 1987
    Date of Patent: April 17, 1990
    Assignee: Intel Corporation
    Inventors: Allen H. Simon, Stuart J. Golin, Brian Astle, John M. Keith, Suz H. Wan