Patents by Inventor John M. Lipari

John M. Lipari has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180021280
    Abstract: The present disclosure provides (a) a pharmaceutical composition comprising a levodopa active agent and a carbidopa active agent and (b) methods of treating Parkinson's disease and associated conditions comprising administering the pharmaceutical composition to a subject with Parkinson's disease.
    Type: Application
    Filed: July 20, 2017
    Publication date: January 25, 2018
    Applicant: AbbVie Inc.
    Inventors: Alexandru DEAC, Ye HUANG, John M. LIPARI, Alexander RUGGLES, Thin Yu TUN
  • Publication number: 20170266289
    Abstract: The invention described herein provides topical formulations that can be prepared at ambient temperature without the need for any heating step during preparation. Thus the formulations are particularly suitable for cosmetic and pharmaceutical active ingredients that are relatively heat sensitive. The invention also provides methods for preparing the same.
    Type: Application
    Filed: August 27, 2015
    Publication date: September 21, 2017
    Applicant: AbbVie Inc.
    Inventors: John M. Lipari, Philip D. Zocharski
  • Patent number: 8895051
    Abstract: A flavoring system for a liquid pharmaceutical composition and pharmaceutical compositions containing such flavoring systems are disclosed. Flavoring systems of the invention include at least one sweetening agent, at least two flavored ingredients, and at least one flavor modifier selected from the group consisting of citric acid, sodium citrate, sodium chloride, and mixtures thereof. At least two of the flavored ingredients are selected from the group consisting of a vanilla flavored ingredient, a peppermint flavored ingredient, a menthol flavored ingredient, a cotton candy flavored ingredient, and mixtures thereof. The one or more sweetening agents comprise glycerin, monoammonium glycyrrhizinate, saccharin sodium, acesulfame potassium, high fructose corn syrup, and/or mixtures thereof.
    Type: Grant
    Filed: May 10, 2013
    Date of Patent: November 25, 2014
    Inventors: Laman Alani, Donald P. Gauwitz, Dilip Kaul, John M. Lipari, Soumojeet Ghosh, Kennan C. Marsh, Richard H. Whelan, Vanik D. Petrossian
  • Publication number: 20130252985
    Abstract: A flavoring system for a liquid pharmaceutical composition and pharmaceutical compositions containing such flavoring systems are disclosed. Flavoring systems of the invention include at least one sweetening agent, at least two flavored ingredients, and at least one flavor modifier selected from the group consisting of citric acid, sodium citrate, sodium chloride, and mixtures thereof. At least two of the flavored ingredients are selected from the group consisting of a vanilla flavored ingredient, a peppermint flavored ingredient, a menthol flavored ingredient, a cotton candy flavored ingredient, and mixtures thereof. The one or more sweetening agents comprise glycerin, monoammonium glycyrrhizinate, saccharin sodium, acesulfame potassium, high fructose corn syrup, and/or mixtures thereof.
    Type: Application
    Filed: May 10, 2013
    Publication date: September 26, 2013
    Inventors: Laman Alani, Donald P. Gauwitz, Dilip Kaul, John M. Lipari, Soumojeet Ghosh, Kennan C. Marsh
  • Patent number: 8501219
    Abstract: A flavoring system for a liquid pharmaceutical composition and pharmaceutical compositions containing such flavoring systems are disclosed. Flavoring systems of the invention include at least one sweetening agent, at least two flavored ingredients, and at least one flavor modifier selected from the group consisting of citric acid, sodium citrate, sodium chloride, and mixtures thereof. At least two of the flavored ingredients are selected from the group consisting of a vanilla flavored ingredient, a peppermint flavored ingredient, a menthol flavored ingredient, a cotton candy flavored ingredient, and mixtures thereof. The one or more sweetening agents comprise glycerin, monoammonium glycyrrhizinate, saccharin sodium, acesulfame potassium, high fructose corn syrup, and/or mixtures thereof.
    Type: Grant
    Filed: January 14, 2010
    Date of Patent: August 6, 2013
    Assignee: AbbVie Inc.
    Inventors: Laman Alani, Donald P. Gauwitz, Dilip Kaul, John M. Lipari, Soumojeet Ghosh, Kennan C. Marsh, Richard H. Whelan, Vanik D. Petrossian
  • Publication number: 20100280055
    Abstract: A flavoring system for a liquid pharmaceutical composition and pharmaceutical compositions containing such flavoring systems are disclosed. Flavoring systems of the invention include at least one sweetening agent, at least two flavored ingredients, and at least one flavor modifier selected from the group consisting of citric acid, sodium citrate, sodium chloride, and mixtures thereof. At least two of the flavored ingredients are selected from the group consisting of a vanilla flavored ingredient, a peppermint flavored ingredient, a menthol flavored ingredient, a cotton candy flavored ingredient, and mixtures thereof. The one or more sweetening agents comprise glycerin, monoammonium glycyrrhizinate, saccharin sodium, acesulfame potassium, high fructose corn syrup, and/or mixtures thereof.
    Type: Application
    Filed: January 14, 2010
    Publication date: November 4, 2010
    Applicant: ABBOTT LABORATORIES
    Inventors: Laman Alani, Donald P. Gauwitz, Dilip Kaul, John M. Lipari, Soumojeet Ghosh, Kennan C. Marsh, Richard H. Whelan, Vanik D. Petrossian
  • Patent number: 7014864
    Abstract: The present invention is directed to a formulation comprising a lipid-regulating agent dissolved in at least one structured lipid as the primary solvent medium for said agent. One or more emulsifiers may be added to the formulation.
    Type: Grant
    Filed: December 18, 1998
    Date of Patent: March 21, 2006
    Assignee: Abbott Laboratories
    Inventors: John M. Lipari, Dawn M. Raymond, Tom Reiland
  • Patent number: 6911214
    Abstract: A flavoring system for a liquid pharmaceutical composition and pharmaceutical compositions containing such flavoring systems are disclosed. Flavoring systems of the invention include at least one sweetening agent, at least two flavored ingredients, and at least one flavor modifier selected from the group consisting of citric acid, sodium citrate, sodium chloride, and mixtures thereof. At least two of the flavored ingredients are selected from the group consisting of a vanilla flavored ingredient, a peppermint flavored ingredient, a menthol flavored ingredient, a cotton candy flavored ingredient, and mixtures thereof. The one or more sweetening agents comprise glycerin, monoammonium glycyrrhizinate, saccharin sodium, acesulfame potassium, high fructose corn syrup, and/or mixtures thereof.
    Type: Grant
    Filed: September 4, 2001
    Date of Patent: June 28, 2005
    Assignee: Abbott Laboratories
    Inventors: Laman Alani, Donald P. Gauwitz, Dilip Kaul, John M. Lipari, Soumojeet Ghosh, Kennan C. Marsh, Richard H. Whelan, Vanik D. Petrossian
  • Patent number: 6838091
    Abstract: The present invention is directed to a formulation comprising a lipid-regulating agent dissolved in at least one monoglyceride as the primary solvent medium for said agent. One or more emulsifiers may be added to the formulation.
    Type: Grant
    Filed: December 18, 1998
    Date of Patent: January 4, 2005
    Assignee: Abbott Laboratories
    Inventors: John M. Lipari, Dawn M. Raymond, Tom Reiland, Yeshwant D. Sanzgiri
  • Patent number: 6814977
    Abstract: The present invention is directed to a formulation comprising a lipid-regulating agent dissolved in at least one medium chain glycerol ester of a fatty acid as the primary solvent medium for said agent. One or more emulsifiers may be added to the formulation.
    Type: Grant
    Filed: December 18, 1998
    Date of Patent: November 9, 2004
    Assignee: Abbott Laboratories
    Inventors: John M. Lipari, Dawn M. Raymond, Tom Reiland
  • Publication number: 20040191207
    Abstract: Delivery compositions having an alpha-hydroxy acid ester and an acylglycerol as part of a carrier composition for pharmaceutical drug actives or prodrugs are described. These formulations display unique properties aiding in the delivery of the drug to a subject.
    Type: Application
    Filed: March 31, 2003
    Publication date: September 30, 2004
    Inventors: John M. Lipari, Michelle A. Long
  • Publication number: 20030203931
    Abstract: Two new crystalline polymorphs of the compound of formula (I) 1
    Type: Application
    Filed: April 18, 2003
    Publication date: October 30, 2003
    Inventors: John B. Cannon, Pawan Hansrani, Russell L. Hertzler, John M. Lipari, Yeshwant D. Sanzgiri, Steven J. Wittenberger
  • Publication number: 20030192163
    Abstract: A method for inserting a heat port into a stamped base unit includes manufacturing a heat port from a hard metal and providing the heat port with a flange and a recessed locking area. The base unit is provided with a counterbored base hole, the base hole including a counterbore area. The heat port is stamped into the counterbored base hole so that the heat port flange coins the base unit material by the counterbore area into the recessed locking area of the heat port.
    Type: Application
    Filed: April 10, 2002
    Publication date: October 16, 2003
    Inventor: John M. Lipari
  • Publication number: 20020090445
    Abstract: A flavoring system for a liquid pharmaceutical composition and pharmaceutical compositions containing such flavoring systems are disclosed. Flavoring systems of the invention include at least one sweetening agent, at least two flavored ingredients, and at least one flavor modifier selected from the group consisting of citric acid, sodium citrate, sodium chloride, and mixtures thereof. At least two of the flavored ingredients are selected from the group consisting of a vanilla flavored ingredient, a peppermint flavored ingredient, a menthol flavored ingredient, a cotton candy flavored ingredient, and mixtures thereof. The one or more sweetening agents comprise glycerin, monoammonium glycyrrhizinate, saccharin sodium, acesulfame potassium, high fructose corn syrup, and/or mixtures thereof.
    Type: Application
    Filed: September 4, 2001
    Publication date: July 11, 2002
    Inventors: Laman Alani, Donald P. Gauwitz, Dilip Kaul, John M. Lipari, Soumojeet Ghosh, Kennan C. Marsh, Richard H. Whelan, Vanik D. Petrossian
  • Publication number: 20020040046
    Abstract: The present invention is directed to a formulation comprising a lipid-regulating agent dissolved or dispersed in at least one oil and an emulsifier or emulsifier blend, the resulting mixture being capable of forming an emulsion upon dilution in an aqueous medium.
    Type: Application
    Filed: March 13, 2000
    Publication date: April 4, 2002
    Inventors: Jitendra P Patel, Yeshwant D Sanzgiri, John M Lipari, Thomas L Reinland
  • Publication number: 20010053385
    Abstract: The present invention is directed to a formulation comprising a lipid-regulating agent dissolved in at least one monoglyceride as the primary solvent medium for said agent. One or more emulsifiers may be added to the formulation.
    Type: Application
    Filed: December 18, 1998
    Publication date: December 20, 2001
    Inventors: JOHN M. LIPARI, DAWN M. RAYMOND, TOM REILAND, YESHWANT D. SANZGIRI
  • Patent number: 6284767
    Abstract: A compound of the formula: is disclosed as an HIV protease inhibitor. Methods and compositions for inhibiting an HIV infection are also disclosed.
    Type: Grant
    Filed: December 8, 1998
    Date of Patent: September 4, 2001
    Assignee: Abbott Laboratories
    Inventors: Hing Leung Sham, Daniel W. Norbeck, Dale J. Kempf, Xiaoqi Chen, David A. Betebenner, Thomas R. Herrin, Gondi N. Kumar, John M. Lipari, Laman Alani, Soumojeet Ghosh, Rong R. Gao, Dilip Kaul
  • Patent number: 6155093
    Abstract: A method of forming metal enclosures specifically for electrical or electronic components which require precision in the formation of enclosure wells for containing the components. In accordance with the present invention the method comprises the steps of initially taking a metal blank having a depth thickness at least sufficient to accommodate a pre-determined enclosure well depth therein; determining the shape and depth of varying dimensions of the predetermined enclosure well; using a coining press and dies to separately cold form the determined shapes and depths which in toto form the desired well, and wherein each of the cold formings causes extrusion of a portion of metal to extend beyond the original depth thickness; after each cold forming with the coining press of the separate shapes and depth, using a metal removal device such as a grinder to remove the metal extrusion portion.
    Type: Grant
    Filed: June 18, 1999
    Date of Patent: December 5, 2000
    Assignee: Coining Technologies, Inc.
    Inventor: John M. Lipari
  • Patent number: 6008192
    Abstract: Binary pharmaceutical compositions comprising (i) a cyclosporine compound, (ii) a hydrophilic phase and (iii) a surfactant provide bioavailability of the active ingredient which is equivalent to that provided by ternary compositions, but without the need for a lipophilic phase.
    Type: Grant
    Filed: March 12, 1998
    Date of Patent: December 28, 1999
    Assignee: Abbott Laboratories
    Inventors: Laman A. Al-Razzak, Panayiotis Pericleous Constantinides, Dilip Kaul, John M. Lipari, Lisa L. McChesney-Harris, Bashar Y. Abdullah
  • Patent number: 4383992
    Abstract: Beta-cyclodextrin forms a water-soluble complex or inclusion compound with steroid compounds having a molecular structure smaller than the interior cavity in the doughnut-shaped molecular structure of beta-cyclodextrin. The resulting inclusion compounds can be used for a variety of applications including aqueous topical ophthalmic preparations and topical dermatological ointments.
    Type: Grant
    Filed: February 8, 1982
    Date of Patent: May 17, 1983
    Inventor: John M. Lipari