Abstract: Methods, formulations, and a system for improved iontophoretic administration of a drug, by, preferably, topical administration of a formulation containing an active vasodilator, rubefacient, or counterirritant agent such as capsaicin on the skin at the electrode site, or, iontophoretic administration of a vasodilator formulation or alpha blocker prior to iontophoretic administration of the drug.

Abstract: Compositions and methods for the transdermal delivery of pharmacologically active chiral compounds are described which are based on the use of enantiomers or mixtures that contain a disproportionate amount of the enantiomers.

Abstract: An apparatus and method for iontophoretic transdermal delivery of exercise simulating agents includes an electrode having disposed therein a drug reservoir comprising a viscosity-control agent comprising an aqueous sol with an antioxidant, a preservative, a chelator and a buffer. A silver/silver chloride conducive element is preferably situated in the electrode adjacent the drug reservoir to conduct an electric charge across the reservoir.

Abstract: The transdermal flux rates of 1,4-dihydropyridine derivatives, such as nilvapidine and its enantiomers may be increased by the use of a solvent vehicle which comprises dioctyl adipate, isopropyl myristate, benzyl alcohol, diisopropyl adipate, a mixture of 5 to 50% ethyl alcohol and 95-50% of diisopropyl adipate, or a mixture of any of the foregoing.

Abstract: Compositions and methods for the transdermal delivery of pharmacologically active chiral compounds are described which are based on the use of enantiomers or mixtures that contain a disproportionate amount of the enantiomers.

Abstract: This invention is directed to an occlusive dressing useful for treating skin lesions and a granular material capable of interacting with wound exudate. Wounds emitting a large amount of fluid can be treated by first packing with the granular material and then covering the wound with the occlusive dressing.

Abstract: This invention is directed to an occlusive dressing useful for treating skin lesions and a granular material capable of interacting with wound exudate. Wounds emitting a large amount of fluid can be treated by first packing with the granular material and then covering the wound with the occlusive dressing.

Abstract: Medical grade adhesive compositions comprising a homogeneous blend of one or more pressure sensitive adhesive materials and one or more natural or synthetic polymers capable of developing elastomeric properties when hydrated such as gluten and long chain polymers of methyl vinyl ether/maleic acid are disclosed. The compositions may also include one or more water soluble hydrocolloid gums and may additionally contain one or more water swellable cohesive strengthening agents.

Abstract: A lyophilized foam sponge product having medically useful hemostatic and adhesive properties formed from the hydrocolloids, gelatin, pectin, and sodium carboxymethylcellulose and having a density of from about 0.01 to about 0.10 grams/cc. The gelatin is present at from about 20% to about 80% by weight of the final product and the pectin and sodium carboxymethylcellulose are each present at from about 10% to about 50% by weight of the final product. The product is prepared by forming an aqueous colloidal dispersion of hydrocolloids, aerating or foaming, freezing, and lyophilizing.