Abstract: A neuromodulation therapy is delivered via at least one electrode implanted subcutaneously and superficially to a fascia layer superficial to a nerve of a patient. In one example, an implantable medical device is deployed along a superficial surface of a deep fascia tissue layer superficial to a nerve of a patient. Electrical stimulation energy is delivered to the nerve through the deep fascia tissue layer via implantable medical device electrodes.

Abstract: A neuromodulation therapy is delivered via at least one electrode implanted subcutaneously and superficially to a fascia layer superficial to a nerve of a patient. In one example, an implantable medical device is deployed along a superficial surface of a deep fascia tissue layer superficial to a nerve of a patient. Electrical stimulation energy is delivered to the nerve through the deep fascia tissue layer via implantable medical device electrodes.

Abstract: Integrated devices that include a sample preparation component integrated with a detection component are disclosed. The sample preparation component may be a digital microfluidics module or a surface acoustic wave module which modules are used for combing a sample droplet with a reagent droplet and for performing additional sample preparation step leading to a droplet that contains beads/particles/labels that indicate presence or absence of an analyte of interest in the sample. The beads/particles/labels may be detected by moving the droplet to the detection component of the device, which detection component includes an array of wells.

Abstract: Integrated devices that include a sample preparation component integrated with a detection component are disclosed. The sample preparation component may be a digital microfluidics module or a surface acoustic wave module which modules are used for combing a sample droplet with a reagent droplet and for performing additional sample preparation step leading to a droplet that contains beads/particles/labels that indicate presence or absence of an analyte of interest in the sample. The beads/particles/labels may be detected by moving the droplet to the detection component of the device, which detection component includes an array of wells.

Abstract: The frequency stability of an optical local oscillator is improved by locking a laser to a silicon Fabry-Perot cavity operating at a temperature near 124 K, where the coefficient of thermal expansion of silicon is near zero. The cavity is mounted inside a cryostat housed in a temperature-stabilized vacuum system that is surrounded by an isolating enclosure and supported by an active vibration platform. Laser light is steered with a superpolished mirror toward a superpolished focusing optic that couples the laser light into the cavity. Light reflected from the cavity is used to stabilize the laser via the Pound-Drever-Hall technique, while light transmitted through the cavity is used to stabilize the laser power. A resonant transimpedance amplifier allows the laser power to be reduced, which reduces heating of the cavity caused by residual absorption of the light.

Abstract: The frequency stability of an optical local oscillator is improved by locking a laser to a silicon Fabry-Perot cavity operating at a temperature near 124 K, where the coefficient of thermal expansion of silicon is near zero. The cavity is mounted inside a cryostat housed in a temperature-stabilized vacuum system that is surrounded by an isolating enclosure and supported by an active vibration platform. Laser light is steered with a superpolished mirror toward a superpolished focusing optic that couples the laser light into the cavity. Light reflected from the cavity is used to stabilize the laser via the Pound-Drever-Hall technique, while light transmitted through the cavity is used to stabilize the laser power. A resonant transimpedance amplifier allows the laser power to be reduced, which reduces heating of the cavity caused by residual absorption of the light.

Abstract: Integrated devices that include a sample preparation component integrated with a detection component are disclosed. The sample preparation component may be a digital microfluidics module or a surface acoustic wave module which modules are used for combing a sample droplet with a reagent droplet and for performing additional sample preparation step leading to a droplet that contains beads/particles/labels that indicate presence or absence of an analyte of interest in the sample. The beads/particles/labels may be detected by moving the droplet to the detection component of the device, which detection component includes an array of wells.

Abstract: Integrated microfluidic and analyte detection devices are disclosed, along with methods of detecting target analytes. Digital microfluidic and analyte detection devices include a first substrate and a second substrate aligned generally parallel to each other to define a gap therebetween, the first substrate including a plurality of electrodes to generate electrical actuation forces on a liquid droplet disposed in the gap; at least one reagent disposed on at least one of the first substrate or the second substrate and configured to be carried by the liquid droplet; and an analyte detection device in fluid communication with the gap, wherein the plurality of electrodes are configured to move the liquid droplet towards the analyte detection device.

Abstract: A motorcycle canopy to protect a motorcycle and a motorcyclist during a rain storm including a collapsible main frame with sub-frames, formed of cylindrical fiberglass rods, pivotally attached to a pivotal body, a waterproof canopy body having sleeves in which the sub-frames are disposed, a mesh screen disposed in the front and rear end of the canopy body for air circulation and heat exhaustion, and a window disposed in the canopy body proximal to a center frame. Securement straps attached to the center frame, a cross-strap disposed across the center frame, and front straps disposed between an upper frame and a motorcycle handlebar secure the device in place during windy conditions.

Abstract: A system and method for estimating and updating the current state of disease of a patient, called the disease impression. The disease impression of the patient, for a disease with a set of possible disease conditions, is updated based upon the current disease impression, the outcome of a test performed with respect to the disease in the patient, and the conditional probabilities of obtaining the test outcome given each of the disease conditions for the disease. The conditional probabilities with respect to all possible outcomes of the test and conditions of the disease may be stored in a likelihood matrix, which comprises a medical knowledge base. Because tests are error prone, the estimate of the patient's state of disease evolves according to a hidden Markov model, which allows the clinical impression of the patient to be computed in real-time.

Abstract: Methods of processing seismic data to remove unwanted noise from meaningful reflection signals are provided for. Assembled seismic data are transformed from the offset-time domain to the time-slowness domain using a Radon transformation. Preferably, the Radon transformation is applied within defined slowness limits pmin and pmax that will preserve coherent noise, and according to an index j of the slowness set and a sampling variable ?p; wherein j = p ma ? ? x - p m ? ? i ? ? n + 1 ? ?sec ? / ? m ? ? ? p , ?p is from about 0.5 to about 4.0 ?sec/m. The coherent noise content of the transformed data is then enhanced, and the primary reflection signal content diminished by filtering at least a subset of the transformed data.

Abstract: Methods of processing seismic data to remove unwanted noise from meaningful reflection signals are provided for. Assembled seismic data are transformed from the offset-time domain to the time-slowness domain using a Radon transformation. Preferably, the Radon transformation is applied within defined slowness limits pmin and pmax that will preserve coherent noise, and according to an index j of the slowness set and a sampling variable ?p; wherein j = p ma ? ? x - p m ? ? i ? ? n + 1 ? ?sec ? / ? m ? ? ? p , ?p is from about 0.5 to about 4.0 ?sec/m. The coherent noise content of the transformed data is then enhanced, and the primary reflection signal content diminished by filtering at least a subset of the transformed data.

Abstract: The message board of the present invention includes a base unit and a writing board that can fit within a channel of the base unit and be removed therefrom. The base unit can include a light and may be operable to be plugged directly into a wall outlet. A switch can also be included on the base unit to activate and deactivate the light. The base has a front surface with an arm extending outwardly therefrom and tie arm having a flange spaced apart from and extending generally parallel to the front surface. The front surface, the arm and the flange define a channel, the channel having a dimension such that the writing board can fit and rest therein. The channel also has a floor region which allows light to shine therethrough. The writing board can have a written message thereon and is operable to allow light to illuminate the written message when placed within the channel of the base and light shines through the floor region of the channel.

Abstract: Methods of processing seismic data to remove unwanted noise from meaningful reflection signals are provided for. Assembled seismic data are transformed from the offset-time domain to the time-slowness domain using a Radon transformation. Preferably, an offset weighting factor xn is applied to the amplitude data, wherein 0<n<1, and the Radon transformation is applied within defined slowness limits pmin and pmax that will preserve coherent noise, and according to an index j of the slowness set and a sampling variable ?p; wherein j = p max - p min + 1 ? ? µ ? ? sec ? / ? m ? ? ? p , ?p is from about 0.5 to about 4.0 ?sec/m. The coherent noise content of the transformed data is then enhanced, and the primary reflection signal content diminished by filtering at least a subset of the transformed data.

Abstract: Methods of processing seismic data to remove unwanted noise from meaningful reflection signals are provided for. The methods comprise the steps of assembling seismic data into common geometry gathers in an offset-time domain without correcting the data for normal moveout. The amplitude data are then transformed from the offset-time domain to the time-slowness domain using a limited Radon transformation. That is, the Radon transformation is applied within defined slowness limits pmin and pmax, where pmin is a predetermined minimum slowness and pmax is a predetermined maximum slowness. A corrective filter is then applied to the transformed data enhance the primary reflection signal content of the data and to eliminate unwanted noise events. After filtering, the enhanced signal content is inverse transformed from the time-slowness domain back to the offset-time domain using an inverse Radon transformation.

Abstract: Disclosed is an interactive toy for providing an audible response to an initial audio signal. The toy is comprised of a housing, a microphone, a controller having speech circuitry and Mask ROM memory, and a speaker. The housing can be in the form of a human figurine and the toy can include an on/off switch which allows for the energizing or de-energizing of the toy. The controller is preferably a microprocessor. In addition, the controller is operable to run in different modes, for example a demo mode and a play mode. The microphone can receive an audio signal from a user and relay the audio signal to the controller. The audio signal can be in the form of a verbal question provided by the user. The controller receives the audio signal from the microphone and selects a message stored in the Mask ROM memory and provides the message to the speaker. The speaker transmits the message to the user in an audible form.

Abstract: Methods of processing seismic data to remove unwanted noise from meaningful reflection signals are provided for. The methods comprise the steps of assembling seismic data into common geometry gathers in an offset-time domain without correcting the data for normal moveout. The amplitude data are then transformed from the offset-time domain to the time-slowness domain using a Radon transformation. At least of subset of the transformed data is filtered to enhance its coherent noise content and to diminish its primary reflection signal content by defining a slowness high-pass region and, a slowness low-pass region. The low-pass region is defined to enhance the low slowness coherent noise content and to diminish the primary reflection signal content thereof, thereby generating a first subset of said transformed data having enhanced low slowness coherent noise content.

Abstract: An apparatus for transporting and filling a freight container, such as an ISO standard intermodal container, with grain or other crop at the point of harvest. The apparatus includes a chassis adapted to support the freight container and a hopper for receiving grain from a harvesting machine. A conveyor moves the grain from the hopper and into the container. The apparatus is pulled by a tractor or can be a self propelled vehicle to move the container through a field to the harvester to receive grain and fill the container while the harvester continues to move through the field harvesting grain.

Abstract: Methods of processing seismic data to remove unwanted noise from meaningful reflection signals are provided for. The seismic data is transformed from the offset-time domain to the time-slowness domain using a limited Radon transformation. That is, the Radon transformation is applied within defined slowness limits pmin and pmax, where pmin is a predetermined minimum slowness and pmax is a predetermined maximum slowness. A corrective filter is then applied to enhance the primary reflection signal content of the data and to eliminate unwanted noise events. After filtering, the enhanced signal content is inverse transformed from the time-slowness domain back to the offset-time domain using an inverse Radon transformation.

Abstract: A cart for filling intermodal shipping containers with a bulk particulate material, such as grain, includes a hopper to receive the bulk material and a belt conveyor to deliver the material to the container. The conveyor is positioned external of the container and throws the material along an arcuate path to the opposite end of the container whereby the container is substantially filled without the need to extend the conveyor into the container. The cart is supported on wheels to be moved where needed. The cart can straddle a standard truck trailer carrying a container so that the container need not be removed from the trailer for filling. The conveyor height is variable to reach a container on a truck trailer or on the ground. The cart width can also be reduced for road transport.