Patents by Inventor John M. Sipes

John M. Sipes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peptide inhibitors of fibronectin and related collagen-binding proteins
    Patent number: 5849701
    Abstract: Peptides derived from the second type 1 repeat of human endothelial cell thrombospondin which bind to the gelatin-binding domain of fibronectin have been isolated and synthetically produced. The peptides can be used to bind to fibronectin or other related collagen-binding proteins to inhibit fibronectin-dependent cell adhesion to collagen matrices and to inhibit interactions with collagen of other proteins that share homologies with the gelatin-binding domain of fibronectin.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: December 15, 1998
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: David D. Roberts, Henry C. Krutzsch, John M. Sipes, Neng-hua Guo, Eric Negre
  • Peptide inhibitors of fibronectin and related collagen-binding proteins
    Patent number: 5491130
    Abstract: Peptides derived from the second type 1 repeat of human endothelial cell thrombospondin which bind to the gelatin-binding domain of fibronectin have been isolated and synthetically produced. The peptides can be used to bind to fibronectin or other related collagen-binding proteins to inhibit fibronectin-dependent cell adhesion to collagen matrices and to inhibit interactions with collagen of other proteins that share homologies with the gelatin-binding domain of fibronectin.
    Type: Grant
    Filed: November 10, 1992
    Date of Patent: February 13, 1996
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: David D. Roberts, Henry C. Krutzsch, John M. Sipes, Neng-hua Guo, Eric Negre