Patents by Inventor John MacLean

John MacLean has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230312466
    Abstract: The invention relates to compounds of formula (I) and related aspects.
    Type: Application
    Filed: September 1, 2021
    Publication date: October 5, 2023
    Applicant: NRG Therapeutics Ltd
    Inventors: Neil MILLER, Richard RUTTER, Jan KULAGOWSKI, Richard MORPHY, Tammy LADDUWAHETTY, John MACLEAN, Eric TALBOT
  • Publication number: 20200359865
    Abstract: A dirt separator for a vacuum cleaner including a chamber having an inlet through which dirt-laden fluid enters the chamber and an outlet through which cleansed fluid exits the chamber; and a disc located at the outlet, the disc being arranged to rotate about a rotational axis and including holes through which the cleansed fluid passes. The disc includes a first region in which a first array of said holes is provided, and a second region, radially outward of the first region, in which a second array of said holes is provided. Each hole of the second array has a larger cross-sectional area than each hole of the first array.
    Type: Application
    Filed: July 30, 2018
    Publication date: November 19, 2020
    Applicant: Dyson Technology Limited
    Inventors: Charles Howard PERCY-RAINE, Tim John MACLEAN, Gregory William DUSSEK, Mateusz GUGALA, Jonathan Bartholomew MURPHY
  • Publication number: 20200214522
    Abstract: A dirt separator for a vacuum cleaner including a chamber having an inlet through which dirt-laden fluid enters the chamber and an outlet through which cleansed fluid exits the chamber; and a disc located at the outlet, the disc being arranged to rotate about a rotational axis, and including holes running from an upstream face to a downstream face through which the cleansed fluid passes. Each hole has a tapered portion which narrows from an upstream end to a downstream end thereof.
    Type: Application
    Filed: July 30, 2018
    Publication date: July 9, 2020
    Applicant: Dyson Technology Limited
    Inventors: Tim John MACLEAN, Mateusz GUGALA, Jonathan Bartholomew MURPHY, Andrew John ISAACS, Charles Howard PERCY-RAINE, Gregory William DUSSEK
  • Publication number: 20200170465
    Abstract: A dirt separator for a vacuum cleaner including a chamber having an inlet through which dirt-laden fluid enters the chamber and an outlet through which cleansed fluid exits the chamber; and a disc located at the outlet, the disc being arranged to rotate about a rotational axis and including holes through which the cleansed fluid passes. When viewed normal to the disc, each hole is elongate and defines a longitudinal axis which runs within the plane of the disc. The longitudinal axis of each hole is curved.
    Type: Application
    Filed: July 30, 2018
    Publication date: June 4, 2020
    Applicant: Dyson Technology Limited
    Inventors: Tim John MACLEAN, Mateusz GUGALA, Charles Howard PERCY-RAINE, Gregory William DUSSEK, Jonathan Bartholomew MURPHY, Andrew John ISAACS
  • Publication number: 20200170464
    Abstract: A dirt separator for a vacuum cleaner including a chamber having an inlet through which dirt-laden fluid enters the chamber and an outlet through which cleansed fluid exits the chamber; and a disc located at the outlet, the disc being arranged to rotate about a rotational axis and including holes through which the cleansed fluid passes. When viewed normal to the disc, each hole is elongate and defines a longitudinal axis which runs within the plane of the disc. The longitudinal axis of each hole is inclined relative to the radial direction of the disc.
    Type: Application
    Filed: July 30, 2018
    Publication date: June 4, 2020
    Applicant: Dyson Technology Limited
    Inventors: Tim John MACLEAN, Mateusz GUGALA, Charles Howard PERCY-RAINE, Gregory William DUSSEK, Jonathan Bartholomew MURPHY, Andrew John ISAACS
  • Publication number: 20200163509
    Abstract: A dirt separator including a chamber having an inlet through which dirt-laden fluid enters the chamber and an outlet through which cleansed fluid exits the chamber, and a disc located at the outlet, the disc being arranged to rotate about a rotational axis and including holes through which the cleansed fluid passes. The holes are distributed over at least first and second regions of the disc, the second region being radially outward of the first region. The porosity of the second region is higher than the porosity of the first region.
    Type: Application
    Filed: July 30, 2018
    Publication date: May 28, 2020
    Applicant: Dyson Technology Limited
    Inventors: Charles Howard PERCY-RAINE, Tim John MACLEAN, Gregory William DUSSEK, Mateusz GUGALA, Jonathan Bartholomew MURPHY
  • Publication number: 20200163510
    Abstract: A dirt separator for a vacuum cleaner including a chamber having an inlet through which dirt-laden fluid enters the chamber and an outlet through which cleansed fluid exits the chamber; and a disc located at the outlet, the disc being arranged to rotate in a predetermined direction about a rotational axis, and including holes running from an upstream face to a downstream face through which the cleansed fluid passes. When viewed along the radial direction of the disc, the path of each hole through the thickness of the disc defines a centreline, the centreline being inclined such that it is non-perpendicular to the disc. The centreline of each hole is inclined such that it intersects the upstream face of the disc at a point which is behind, in the direction of rotation of the disc, the point at which the centreline intersects the downstream face of the disc.
    Type: Application
    Filed: July 30, 2018
    Publication date: May 28, 2020
    Applicant: Dyson Technology Limited
    Inventors: Tim John MACLEAN, Mateusz GUGALA, Charles Howard PERCY-RAINE, Gregory William DUSSEK, Jonathan Bartholomew MURPHY, Andrew John ISAACS
  • Patent number: 10459915
    Abstract: Managing queries performed on one or more data sources includes: storing at least a first query in a storage medium; selecting the first query for processing; instructing a query engine to process the first query on a first portion of data in the one or more data sources for a first query interval; receiving result data from the query engine based on processing the first query on the first portion of data; saving a state of the first query in the storage medium after the first query interval; instructing the query engine to process a second query during a second query interval after the first query interval; and instructing the query engine to process the first query on a second portion of data in the one or more data sources during a third query interval after the second query interval.
    Type: Grant
    Filed: December 23, 2010
    Date of Patent: October 29, 2019
    Assignee: Ab Initio Technology LLC
    Inventors: Craig W. Stanfill, John Maclean
  • Patent number: 10213793
    Abstract: A cyclonic separation apparatus includes an outer wall, an inner wall and a cyclonic chamber defined between the outer wall and inner wall. A section of the surfaces of both the outer wall and the inner wall are flattened. The inner wall and the outer wall are also concentrically arranged. During use a fluid moving around the cyclonic chamber flows between a curved passage and a flattened passage of the cyclonic chamber.
    Type: Grant
    Filed: January 19, 2017
    Date of Patent: February 26, 2019
    Assignee: Dyson Technology Limited
    Inventors: Tim John Maclean, Richard Allix Braine, Joshua James Tunstill, Ashley Jane Caddle
  • Patent number: 9844553
    Abstract: This invention relates to pyrazolopyridyl compounds of the structural formula: or their pharmaceutically acceptable salts, wherein the variable are defined herein. The inventive compounds selectively inhibit aldosterone synthase. This invention also provides for pharmaceutical compositions comprising the compounds of Formula I or their salts as well as potentially to methods for the treatment, amelioration or prevention of conditions that could be treated by inhibiting aldosterone synthase.
    Type: Grant
    Filed: April 27, 2016
    Date of Patent: December 19, 2017
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: D. Jonathan Bennett, Jaiqiang Cai, Emma Carswell, Andrew Cooke, Scott B. Hoyt, Clare London, John MacLean, Min K. Park, Paul Ratcliffe, Yusheng Xiong, Swapan Kumar Samanta, Bheemashankar A. Kulkarni
  • Patent number: 9797229
    Abstract: A method of setting the value of an operational parameter of a well is provided. The method includes providing a measure related to the actual value of the parameter; setting a maximum limit for the measure; setting a minimum limit for the measure; setting a demanded value for the parameter; and automatically overriding the demanded value if it is such that it would result in the measure exceeding the maximum limit or being below the minimum limit to produce an actual value for the parameter with results in the measure not exceeding the maximum limit and not being below the minimum limit.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: October 24, 2017
    Assignee: GE Oil & Gas UK Limited
    Inventor: John Maclean Wingate
  • Patent number: 9783511
    Abstract: The invention provides certain benzoxazine compounds of the Formula (I) or pharmaceutically acceptable salts thereof wherein R1, R2, Ra1, Ra2, Rb1, Rb2, Rc, Rd, and Cy are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds of the Formula (I) or pharmaceutically acceptable salts thereof, and methods of using the compounds of the Formula (I) or pharmaceutically acceptable salts thereof or pharmaceutical compositions comprising the same for treating diseases or conditions mediated by RORgammaT.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: October 10, 2017
    Assignees: Lycera Corporation, Merck Sharp & Dohme Corp.
    Inventors: Thomas D. Aicher, Chad A. VanHuis, John MacLean, Brian M. Andresen, Kenneth J. Barr, Corey Bienstock, Matthew Daniels, Kun Liu, Yuan Liu, Catherine White, Nunzio Sciammetta, Vladimir Simov
  • Publication number: 20170209875
    Abstract: A cyclonic separation apparatus includes an outer wall, an inner wall and a cyclonic chamber defined between the outer wall and inner wall. A section of the surfaces of both the outer wall and the inner wall are flattened. The inner wall and the outer wall are also concentrically arranged. During use a fluid moving around the cyclonic chamber flows between a curved passage and a flattened passage of the cyclonic chamber.
    Type: Application
    Filed: January 19, 2017
    Publication date: July 27, 2017
    Applicant: Dyson Technology Limited
    Inventors: Tim John MACLEAN, Richard Allix BRAINE, Joshua James TUNSTILL, Ashley Jane CADDLE
  • Publication number: 20170177446
    Abstract: A method performed by a data processing system for processing data, the method including: intermittently receiving data from one or more data streams, the received data including data records; detecting two or more particular data records in the received data records, where the detected two or more particular data records each include a particular identifier; for that particular identifier, creating a collection of data records; for at least one particular data record included in the collection of data records, searching data records for a historical aggregation of data; and computing combined data; modifying a data record by inserting the combined data into a field of the data record and by inserting data from at least one of the data records in the collection into another field of the data record; based on applying the rules, writing to memory one or more instructions for initiation of one or more actions.
    Type: Application
    Filed: November 23, 2016
    Publication date: June 22, 2017
    Inventors: John MacLean, Paul Veiser
  • Patent number: 9663502
    Abstract: The invention provides certain benzoxazine compounds of the Formula (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, Ra, Rb, Rc, Rd, Rg, and Cy are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds of the Formula (I) or pharmaceutically acceptable salts thereof, and methods of using the compounds of the Formula (I) or pharmaceutically acceptable salts thereof or pharmaceutical compositions comprising the same for treating diseases or conditions mediated by RORgammaT.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: May 30, 2017
    Assignees: Lycera Corporation, Merck Sharp & Dohme Corp.
    Inventors: Thomas D. Aicher, Chad A. VanHuis, John MacLean, Brian M. Andresen, Kenneth J. Barr, Corey Bienstock, Neville J. Anthony, Matthew Daniels, Yuan Liu, Catherine White, Blair T. Lapointe, Nunzio Sciammetta, Vladimir Simov, Wesley B. Trotter, Kun Liu
  • Patent number: 9567333
    Abstract: This invention relates to triazolopyridyl compounds of the structural formula: or their pharmaceutically acceptable salts, wherein the variable are defined herein. The inventive compounds selectively inhibit aldosterone synthase. This invention also provides for pharmaceutical compositions comprising the compounds of Formula I or their salts as well as potentially to methods for the treatment, amelioration or prevention of conditions that could be treated by inhibiting aldosterone synthase.
    Type: Grant
    Filed: October 19, 2015
    Date of Patent: February 14, 2017
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: D. Jonathan Bennett, Jaiqiang Cai, Emma Carswell, Andrew Cooke, Scott B. Hoyt, Clare London, John MacLean, Paul Ratcliffe, Jerry Andrew Taylor, Yusheng Xiong, Swapan Kumar Samanta, Bheemashankar A. Kulkarni
  • Publication number: 20170020879
    Abstract: This invention relates to pyrazolopyridyl compounds of the structural formula: or their pharmaceutically acceptable salts, wherein the variable are defined herein. The inventive compounds selectively inhibit aldosterone synthase. This invention also provides for pharmaceutical compositions comprising the compounds of Formula I or their salts as well as potentially to methods for the treatment, amelioration or prevention of conditions that could be treated by inhibiting aldosterone synthase.
    Type: Application
    Filed: April 27, 2016
    Publication date: January 26, 2017
    Inventors: D. Jonathan Bennett, Jaiqiang Cai, Emma Carswell, Andrew Cooke, Scott B. Hoyt, Clare London, John MacLean, Min K. Park, Paul Ratcliffe, Yusheng Xiong, Swapan Kumar Samanta, Bheemashankar A. Kulkarni
  • Patent number: 9518055
    Abstract: This invention relates to imidazopyridyl compounds of the structural formula: or their pharmaceutically acceptable salts, wherein the variable are defined herein. The inventive compounds selectively inhibit aldosterone synthase. This invention also provides for pharmaceutical compositions comprising the compounds of Formula I or their salts as well as potentially to methods for the treatment, amelioration or prevention of conditions that could be treated by inhibiting aldosterone synthase.
    Type: Grant
    Filed: October 16, 2015
    Date of Patent: December 13, 2016
    Assignee: Merck Sharp & Dohme
    Inventors: Amjad Ali, D. Jonathan Bennett, Jaiqiang Cai, Emma Carswell, Andrew Cooke, Scott B. Hoyt, Michael Lo, Clare London, John MacLean, Min K. Park, Paul Ratcliffe, Jerry Andrew Taylor, Brent Whitehead, Yusheng Xiong
  • Publication number: 20160311787
    Abstract: The invention provides certain benzoxazine compounds of the Formula (I) or pharmaceutically acceptable salts thereof wherein R1, R2, Ra1, Ra2, Rb1, Rb2, Rc, Rd, and Cy are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds of the Formula (I) or pharmaceutically acceptable salts thereof, and methods of using the compounds of the Formula (I) or pharmaceutically acceptable salts thereof or pharmaceutical compositions comprising the same for treating diseases or conditions mediated by RORgammaT.
    Type: Application
    Filed: December 19, 2014
    Publication date: October 27, 2016
    Inventors: Thomas D. Aicher, Chad A. VanHuis, John MacLean, Brian M. Andresen, Kenneth J. Barr, Corey Bienstock, Matthew Daniels, Kun Liu, Yuan Liu, Catherine White, Nunzio Sciammetta, Vladimir Simov
  • Publication number: 20160304505
    Abstract: The invention provides certain benzoxazine compounds of the Formula (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, Ra, Rb, Rc, Rd, Rg, and Cy are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds of the Formula (I) or pharmaceutically acceptable salts thereof, and methods of using the compounds of the Formula (I) or pharmaceutically acceptable salts thereof or pharmaceutical compositions comprising the same for treating diseases or conditions mediated by RORgammaT.
    Type: Application
    Filed: December 19, 2014
    Publication date: October 20, 2016
    Inventors: Thomas D. Aicher, Chad A. VanHuis, John MacLean, Brian M. Andresen, Kenneth J. Barr, Corey Bienstock, Neville J. Anthony, Matthew Daniels, Yuan Liu, Catherine White, Blair T. Lapointe, Nunzio Sciammetta, Vladimir Simov, Wesley B. Trotter, Kun Liu