Patents by Inventor John Malcolm Curling

John Malcolm Curling has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of isolating albumin from blood products
    Patent number: 4086222
    Abstract: This invention relates to a new method of isolating highly purified albumin in high yields from plasma products.According to the invention a particular plasma fraction, containing albumin in dissolved form and being essentially free from the coagulation factors I, II, VII, VIII, IX and X and from the main part of IgG, is subjected to a two-step chromatographic separation using aqueous buffer systems. The first step is carried out on an anion exchanger and the second step on a cation exchanger, or vice versa. In a preferred embodiment a buffer of pH 4.5 - 4.9 and an ionic strength of 0.025 - 0.1 is used for the separation on the anion exchanger, whereas a buffer of pH 5.2 - 6.5 and an ionic strength of 0.1 - 0.05 is used for the separation on the cation exchanger.
    Type: Grant
    Filed: September 28, 1976
    Date of Patent: April 25, 1978
    Assignee: Pharmacia Fine Chemicals AB
    Inventors: Lars-Olof Edvard Lindquist, Jan Hakan Berglof, John Malcolm Curling