Abstract: A method for selectively separating desirable steroidal glycosides from undesirable components present in plant material of the Asclepiadaceae family containing the same. The method comprises contacting the plant material or material derived therefrom (herein: “the material”) with liquid or supercritical carbon dioxide under conditions whereby the desirable steroidal glycosides dissolve in the liquid or supercritical carbon dioxide in preference to the undesirable components, and subsequently recovering the desirable steroidal glycosides from the carbon dioxide solution.

Abstract: A safety device (10) comprises a plurality of wheel nut position indicators (30) captively but rotatably mounted in a holder (12). The position indicators are attachable to respective wheel nuts (40) by means of fastener covers (50). When attached, the fastener covers (50) act to secure the device to a wheel and to transfer any rotational movement, i.e. loosening, of a wheel nut (40) to an associated position indicator (30). The indicators (30) each have an indicator portion, e.g. a triangular pointer (34) and are so arranged that this portion emerges from the holder and hence becomes visible when any such rotation occurs. By removing a fastener cover (50) an indicator (30) is disengaged from a wheel nut (40) and the individual wheel nut can be tightened without having to remove the entire device (10).

Abstract: A safety device (10) comprises a plurality of wheel nut position indicators (30) captively but rotatably mounted in a holder (12). The position indicators are attachable to respective wheel nuts (40) by means of fastener covers (50). When attached, the fastener covers (50) act to secure the device to a wheel and to transfer any rotational movement, i.e. loosening, of a wheel nut (40) to an associated position indicator (30). The indicators (30) each have an indicator portion, e.g. a triangular pointer (34) and are so arranged that this portion emerges from the holder and hence becomes visible when any such rotation occurs. By removing a fastener cover (50) an indicator (30) is disengaged from a wheel nut (40) and the individual wheel nut can be tightened without having to remove the entire device (10).