Abstract: Sublingual or buccal dosage forms comprise at least one antioxidant compound, such as N-acetyl cysteine (NAC), or a pharmaceutically acceptable salt thereof. The sublingual or buccal dosage forms are administered for treating central nervous system (CNS) disorders, such as traumatic brain injury or stroke.

Abstract: The hemitartrate salt of a compound represented by the following structural formula: (Formula I Hemitartrate), which may be used in pharmaceutical applications, are disclosed. Particular single crystalline forms of the Formula (I) Hemitartrate are characterized by a variety of properties and physical measurements. As well, methods of producing crystalline Formula (I) Hemitartrate, and using it to inhibit glucosylceramide synthase or lowering glycosphingolipid concentrations in subjects to treat a number of diseases, are also discussed. Pharmaceutical compositions are also described.

Abstract: The present invention relates to a novel chemical compound for use in the treatment of cancer, to compositions containing said compound, methods of manufacture and combinations with other therapeutic agents.

Abstract: Systems and methods are described for a messaging agent for managed multidimensional search based on an electronic message and management policies. A messaging application at a client device can send a new electronic message, such as an email, to a connector service. An attachment can be ingested and stored in a vector database. Then one or more artificial intelligence (“AI”) agents can be selected for responding to the body of the email, such as a query in the body. The responses can be formatted and sent to multiple users, such as a sending user of the electronic message and a recipient user that was copied or also sent the new electronic message. The AI agents can use different AI models, prompts, and vector databases depending on user permissions. This allows for building up vector databases with relevant content items and answering user questions based on those vector databases.

Abstract: Systems and methods are described for a connected AI agent for managed multidimensional search based on an electronic message and management policies. A messaging application at a client device can send a new electronic message, such as an email, to a connector service. An attachment can be ingested and stored in a vector database. Then one or more artificial intelligence (“AI”) agents can be selected for responding to the body of the email, such as a query in the body. The responses can be formatted and sent to multiple parties, such as a sending user of the electronic message and a recipient that was copied or also sent the new electronic message. The AI agents can use different AI models, prompts, and vector databases depending on user permissions. This allows for building up vector databases with relevant content items and answering user questions based on those vector databases.

Abstract: Systems and methods are described for a connected AI agent for managed multidimensional search based on an electronic message and management policies. A messaging application at a client device can send a new electronic message, such as an email, to a connector service. An attachment can be ingested and stored in a vector database. Then one or more artificial intelligence (“AI”) agents can be selected for responding to the body of the email, such as a query in the body. The responses can be formatted and sent to multiple parties, such as a sending user of the electronic message and a recipient that was copied or also sent the new electronic message. The AI agents can use different AI models, prompts, and vector databases depending on user permissions. This allows for building up vector databases with relevant content items and answering user questions based on those vector databases.

Abstract: Systems and methods are described for executing customer artificial intelligence pipelines by dynamically selecting service providers based on resource consumption. A server can poll a group of service providers and receive resource information that indicates compute, network, storage, and token requirements to perform an action. When the customer AI pipeline executes, a pipeline engine can select a service provider to execute the action based on stored resource information. The service providers available in the group can also dynamically change based on terms of service.

Abstract: Systems and methods are described for executing tenant artificial intelligence pipelines by dynamically selecting service providers based on resource consumption. A server can poll a group of service providers and receive resource information that indicates compute, network, storage, and token requirements to perform an action. When the tenant AI pipeline executes, a pipeline engine can select a service provider to execute the action based on stored resource information. The service providers available in the group can also dynamically change based on terms of service.

Abstract: Systems and methods are described for a messaging agent for managed multidimensional search based on an electronic message and management policies. A messaging application at a client device can send a new electronic message, such as an email, to a connector service. An attachment can be ingested and stored in a vector database. Then one or more artificial intelligence (“AI”) agents can be selected for responding to the body of the email, such as a query in the body. The responses can be formatted and sent to multiple users, such as a sending user of the electronic message and a recipient user that was copied or also sent the new electronic message. The AI agents can use different AI models, prompts, and vector databases depending on user permissions. This allows for building up vector databases with relevant content items and answering user questions based on those vector databases.

Abstract: Systems and methods are described for a connected AI agent for managed multidimensional search based on an electronic message and management policies. A messaging application at a client device can send a new electronic message, such as an email, to a connector service. An attachment can be ingested and stored in a vector database. Then one or more artificial intelligence (“AI”) agents can be selected for responding to the body of the email, such as a query in the body. The responses can be formatted and sent to multiple parties, such as a sending user of the electronic message and a recipient that was copied or also sent the new electronic message. The AI agents can use different AI models, prompts, and vector databases depending on user permissions. This allows for building up vector databases with relevant content items and answering user questions based on those vector databases.

Abstract: The invention includes a UI that allows addition of functional placeholders to an AI pipeline, and a rules engine that chooses pipeline objects during or before AI pipeline execution. The rules engine can select pipeline objects meeting the same function type and object rules of the functional placeholder. The rules engine also applies customizable security rules and artificial intelligence (AI) model routing to queries. Remedial actions are taken when the rule evaluation exceeds a threshold. The remedial actions include transforming the query by replacing sensitive information with a reversible placeholder. The actual result can be modified by reversing the placeholder and redacting additional sensitive information. The system can notify the user, an administrator, and a supervisor regarding the security evaluation and remedial actions. The evaluations can be logged for auditing purposes.

Abstract: Systems and methods are described for a messaging agent for managed multidimensional search based on an electronic message and management policies. A messaging application at a client device can send a new electronic message, such as an email, to a connector service. An attachment can be ingested and stored in a vector database. Then one or more artificial intelligence (“AI”) agents can be selected for responding to the body of the email, such as a query in the body. The responses can be formatted and sent to multiple users, such as a sending user of the electronic message and a recipient user that was copied or also sent the new electronic message. The AI agents can use different AI models, prompts, and vector databases depending on user permissions. This allows for building up vector databases with relevant content items and answering user questions based on those vector databases.

Abstract: This invention relates to an apparatus for obstructing the open end of vertical corner channel pieces of siding often used in residential building applications. Siding terminates at the corners of buildings into a vertical corner channel piece that is typically open on its top and bottom ends. This opening provides opportunity for small animals to enter and damage the building. This invention comprises an enclosing cap with a bottom surface to obstruct the opening of the vertical corner channel piece and two exterior surfaces along with two interior pinching surfaces that secure the apparatus onto the siding piece. This enclosing cap provides an attractive and inexpensive solution to the problem of small animals entering spaces located underneath siding.

Abstract: Systems and methods are described for a connected AI agent for managed multidimensional search based on an electronic message and management policies. A messaging application at a client device can send a new electronic message, such as an email, to a connector service. An attachment can be ingested and stored in a vector database. Then one or more artificial intelligence (“AI”) agents can be selected for responding to the body of the email, such as a query in the body. The responses can be formatted and sent to multiple parties, such as a sending user of the electronic message and a recipient that was copied or also sent the new electronic message. The AI agents can use different AI models, prompts, and vector databases depending on user permissions. This allows for building up vector databases with relevant content items and answering user questions based on those vector databases.

Abstract: Disclosed are various embodiments for controlling access to data on a network. Upon receiving a request comprising a device identifier and at least one user credential to access a remote resource, the request may be authenticated according to at least one compliance policy. If the request is authenticated, a resource credential associated with the remote resource may be provided.

Abstract: The present disclosure generally relates to methods and formulations for treating central nervous system (CNS) disorders. The present disclosure involves intranasal delivery of at least one antioxidant compound, allowing for effective treatment of a central nervous system disorder such as traumatic brain injury or stroke.

Abstract: A broadcast spreader broadly comprising a frame, a hopper, an impeller, a set of wheels, and an electric hub motor. The hopper is supported by the frame and configured to hold a particulate material. The impeller is rotatably connected below the hopper and is configured to receive the particulate material from the hopper and spread the particulate material over a surface. The wheels are rotatably connected to the frame for traversing the surface. The electric hub motor is at least partially positioned in one of the wheels and configured to drivably engage the one of the wheels to propel the hopper along the surface.

Abstract: The present disclosure generally relates to methods and formulations for treating central nervous system (CNS) disorders. The present disclosure involves intranasal delivery of at least one antioxidant compound, allowing for effective treatment of a central nervous system disorder such as traumatic brain injury or stroke.

Abstract: The present invention provides to compositions and methods useful in the treatment of neurological disorders including, but not limited to, Angelman syndrome, depression, traumatic brain injury, stroke, and Alzheimer's disease. CN2097, a rationally designed cyclic peptidomimetic drug that has been demonstrated to have effectiveness in preclinical models for the treatment of neurological disorders, is rapidly cleared and has a short half-life. The present invention provides a stable analog of CN2097.

Abstract: The invention includes a UI that allows addition of functional placeholders to an AI pipeline, and a rules engine that chooses pipeline objects during or before AI pipeline execution. The rules engine can select pipeline objects meeting the same function type and object rules of the functional placeholder. The rules engine also applies customizable security rules and artificial intelligence (AI) model routing to queries. Remedial actions are taken when the rule evaluation exceeds a threshold. The remedial actions include transforming the query by replacing sensitive information with a reversible placeholder. The actual result can be modified by reversing the placeholder and redacting additional sensitive information. The system can notify the user, an administrator, and a supervisor regarding the security evaluation and remedial actions. The evaluations can be logged for auditing purposes.