Abstract: Compositions and methods for inhibiting, treating, and/or preventing a B-cell neoplasm are provided.

Abstract: A light-emitting system (1000) removably attachable to headgear is provided, which comprises: a form factor (1010) configured to surround a portion of the headgear when the light-emitting system (1000) is removably attached to the headgear for use; a plurality of halo lighting elements (1100) configured to selectively generate at least a partial halo of light that radiates outwardly away from the light-emitting system; and at least one task lighting element (1120) aligned in a direction along a task light axis (1130) that is fixed and oriented downwardly at an oblique angle (?) relative to a transverse plane (TP) of the light-emitting system (1000), the at least one task lighting element (1120) being configured to selectively generate flood task lighting in an area in front of a user.

Abstract: The article of footwear further includes a heel cup attached to the upper and extending from the sole structure to at least a portion of the rear heel collar of upper. Additionally, the heel cup is uniformly molded with an upper portion, midportion, and lower portion and the upper portion has a smaller mediolateral length than the midportion, and the midportion and lower portion form a concave structure configured to receive the heel. The midportion includes a peripheral portion having a first thickness and a central portion having a second thickness, and the second thickness is less than the first thickness.

Abstract: A shoe includes a heel counter with a heel cup. The heel cup may be uniformly molded with an upper portion, midportion, and a lower portion. The upper portion has a smaller mediolateral length than the midportion, and a thickness of the heel cup decreases from a peripheral portion of the heel cup toward a central region of the midportion. The central region of the midportion provides flexibility of the heel cup, and the rearmost portion of the heel cup has an overall vertical S wave cross-sectional shape.

Abstract: Systems and techniques are described for monitoring energy use habits of consumers. In some implementations, a method includes obtaining temperature data from a monitored property. An energy model of the monitored property is generated based on the obtained temperature data. The current temperature data is obtained from the monitored property. The current temperature data is provided to the generated energy model to generate a duty-cycle for turning an HVAC system of the monitored property off an on during the on-peak hours. The HVAC system of the monitored property is instructed to cycle off and on during the on-peak hours based on the generated duty-cycle.

Abstract: Mask interfaces having mask frames and mask seals are disclosed. Headgear and breathing conduits can be connected to the mask interfaces. The connection between the mask seals and the mask frames can enable movement of the mask seals relative to the mask frames. The relative movement may be at the mounting locations of the mask seals and mask frames.

Abstract: Communication systems, methods, and non-transitory machine-readable storage media are disclosed herein. A communication system may include a communication device configured to receive a video stream including sign language content and any content indicators associated with the video stream during a real-time communication session within a single communication device or between a plurality of communication devices. The communication system may also include a translation engine configured to automatically translate the sign language content into word content during the real-time communication session without assistance of a human sign language interpreter. Further, the communication system may be configured to output the word content translation to a communication device during the real-time communication session.

Abstract: A patient interface includes a mask body, an elbow, a connector and a conduit. Any one or more of the mask body, the elbow, the connector and the conduit includes a bias flow vent. The bias flow vent is configured to deform with the application of pressure but not fully collapse such that an orifice size defined by the bias flow vent can vary with the application of pressure.

Abstract: A humidification system for delivering humidified gases to a user can include a heater base, humidification chamber having an inlet, outlet, and associated fluid conduit, and breathing circuit including a supply conduit, inspiratory conduit, and optional expiratory conduit. The humidification system can include various features to help make set-up less difficult and time-consuming. For example, the supply conduit, inspiratory conduit, and optional expiratory conduit can be coupled into a one-piece circuit to aid set-up. Various components can be color-coded and can have corresponding structures to indicate which components should be connected to one another during set-up. Such features can also help make the set-up process more intuitive for an operator, which can reduce the need for specialized training and reduce the number of potential errors.

Abstract: A user classification system is provided. The system includes a sensor for producing a sensor signal and a user device. The system classifies a user of the system based on the sensor signal.

Abstract: Interfaces for positive pressure therapy having a mask assembly, a headgear assembly and a connection port assembly are disclosed herein. The connection port assembly has a ball joint connection with the mask assembly and includes a quick release button for easily disconnecting the gases source conduit from the mask assembly. The mask assembly may include a bias flow vent that is formed separately and attached to the mask assembly. The headgear assembly encircles the rear region of the user's head and may include at least some portions that are substantially non-stretchable.

Abstract: The article of footwear further includes a heel cup attached to the upper and extending from the sole structure to at least a portion of the rear heel collar of upper. Additionally, the heel cup is uniformly molded with an upper portion, midportion, and lower portion and the upper portion has a smaller mediolateral length than the midportion, and the midportion and lower portion form a concave structure configured to receive the heel. The midportion includes a peripheral portion having a first thickness and a central portion having a second thickness, and the second thickness is less than the first thickness.

Abstract: Embodiments of the invention provide systems and methods of generating a complete and accurate geometrically optimized environment. Stereo pair images depicting an environment are selected from a plurality of images to generate a Digital Surface Model (DSM). Characteristics of objects in the environment are determined and identified. The geometry of the objects may be determined and fit with polygons and textured facades. By determining the objects, the geometry, and the material from original satellite imagery and from a DSM created from the matching stereo pair point clouds, a complete and accurate geometrically optimized environment is created.

Abstract: A shoe includes a sole and an upper having a heel counter with a heel cup. The upper includes a foot receiving shoe opening. The heel cup is uniformly molded with an upper portion, midportion, and lower portion. On a vertical cross-section, the heel cup has a S wave shape and a thickness of the heel cup decreases gradually from a peripheral portion of the heel cup toward a central region of the heel cup. The heel cup is attached to an interior compressible layer, and the compressible layer extends into the shoe opening. The compressible layer may be compressed by a user's foot during insertion or removal of the user's foot, and may at least partially expand to hold an ankle of the user's foot once the foot is inserted.

Abstract: A shoe has an upper with a foot receiving shoe opening. A heel counter is located at a rear portion of the upper and includes a rigid heel cup. The heel cup has a lower portion, a midportion, and an upper portion having a curvature extending from a top edge of the heel cup and that is curved downward towards the shoe opening. On a vertical cross-section, the heel cup has a S wave shape. A compressible layer is located along an inner wall of the heel cup and is configured to curve around a portion of a user's ankle above the user's heel once donned. The compressible layer may be compressed during donning of the shoe and may at least partially expand to secure the foot within the shoe once donned.

Abstract: A system for performing a medical procedure on a patient is provided. The system comprises at least one of: an energy delivery device: a chronic energy delivery device; and/or a force applying device. In particular, the system can be configured to treat and/or diagnose a patient suffering from sleep apnea. Methods and devices for treating sleep apnea and other medical conditions are also provided.

Abstract: An article of footwear includes a heel cup that is attached to the upper and extends from the sole structure to at least a portion of the rear heel collar of the upper. The heel cup may be uniformly molded with an upper portion, midportion, and lower portion and the upper portion has a smaller mediolateral length than the midportion, and the midportion and lower portion form a concave structure that receives the heel. The upper portion has a first configuration and is capable of distorting into a second configuration under a load of a user's foot when the user is donning the footwear. In the second configuration, at least part of the upper portion is lowered and is capable of returning to the first configuration after the load of the user's foot is removed. The midportion includes a peripheral portion that may be thicker than a central portion.