Patents by Inventor John McBride

John McBride has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20260146256
    Abstract: The present disclosure provides yeasts, which can be recombinant yeast host cells, exhibiting prolonged persistence when submitted to a plurality of fermentation cycles. The yeasts exhibit at least one of the following phenotypic trait: a fast settling phenotype, a rugose phenotype, an improved invertase activity, triploidy, increased signaling in a RAS/cAMP/PKA pathway or combinations thereof.
    Type: Application
    Filed: July 16, 2025
    Publication date: May 28, 2026
    Inventors: Emily Agnes Stonehouse, John McBride, Justin Van Rooyen, Zach Losordo, Petra Deane
  • Publication number: 20250346873
    Abstract: The present disclosure concerns polypeptide having fumonisin esterase activity exhibiting increased fumonisin esterase activity, when measured at a temperature of at least 37° C., when compared to the control polypeptide comprising the amino acid of SEQ ID NO: 3. The polypeptides of the present disclosure include one or more amino acid variations which contribute to the increase fumonisin esterase activity. The present disclosure also includes compositions comprising the polypeptide having fumonisin esterase activity, methods for detoxifying a fumonisin mycotoxin as well as processes for making the compositions comprising the polypeptide having fumonisin esterase activity.
    Type: Application
    Filed: January 26, 2023
    Publication date: November 13, 2025
    Inventors: Allan FROEHLICH, Shelly CHENG, Erin WISWALL, John MCBRIDE
  • Patent number: 12385052
    Abstract: The present disclosure provides yeasts, which can be recombinant yeast host cells, exhibiting prolonged persistence when submitted to a plurality of fermentation cycles. The yeasts exhibit at least one of the following phenotypic trait: a fast settling phenotype, a rugose phenotype, an improved invertase activity, triploidy, increased signaling in a RAS/cAMP/PKA pathway or combinations thereof.
    Type: Grant
    Filed: June 17, 2022
    Date of Patent: August 12, 2025
    Assignee: Danstar Ferment AG
    Inventors: Emily Agnes Stonehouse, John McBride, Justin Van Rooyen, Zach Losordo, Petra Deane
  • Publication number: 20250011809
    Abstract: This invention relates to the production of viral vectors. More specifically, the invention relates to amphipathic cell penetrating peptides for use in the production of viral vectors, and methods of using such peptides, as well as populations of viral vectors produced using such peptides.
    Type: Application
    Filed: May 27, 2021
    Publication date: January 9, 2025
    Inventors: Jonathan APPLEBY, Gregory BERGER, Natacha AGABALYAN, Matthew SMART, Tristan THWAITES, John MCBRIDE, Helen MCCARTHY
  • Patent number: 11638505
    Abstract: A wipe dispensing system including a wall-mountable dispenser adapted to clamp a bag of wipes and optional saturating fluid in place in hanging relation below the dispenser such that no additional support structure is required. The mounting locations can be selected to provide access at varying heights directly against a wall without relying on a shelf thereby promoting availability to wheelchair users. Moreover, very little space is required since the bags hang down against the support wall thereby maintaining a relatively small outwardly projecting profile.
    Type: Grant
    Filed: November 9, 2021
    Date of Patent: May 2, 2023
    Assignee: CONTEC, INC.
    Inventors: John McBride, Jeremy Parker Davis
  • Publication number: 20230026548
    Abstract: The present disclosure provides yeasts, which can be recombinant yeast host cells, exhibiting prolonged persistence when submitted to a plurality of fermentation cycles. The yeasts exhibit at least one of the following phenotypic trait: a fast settling phenotype, a rugose phenotype, an improved invertase activity, triploidy, increased signaling in a RAS/cAMP/PKA pathway or combinations thereof.
    Type: Application
    Filed: June 17, 2022
    Publication date: January 26, 2023
    Inventors: Emily Agnes Stonehouse, John McBride, Justin Van Rooyen, Zach Losordo, Petra Deane
  • Publication number: 20220142419
    Abstract: A wipe dispensing system including a wall-mountable dispenser adapted to clamp a bag of wipes and optional saturating fluid in place in hanging relation below the dispenser such that no additional support structure is required. The mounting locations can be selected to provide access at varying heights directly against a wall without relying on a shelf thereby promoting availability to wheelchair users. Moreover, very little space is required since the bags hang down against the support wall thereby maintaining a relatively small outwardly projecting profile.
    Type: Application
    Filed: November 9, 2021
    Publication date: May 12, 2022
    Inventors: John McBride, Jeremy Parker Davis
  • Publication number: 20210388398
    Abstract: The present invention is directed to cellulytic host cells. The host cells of the invention expressing heterologous cellulases and are able to produce ethanol from cellulose. According to the invention, host cells expressing a combination of heterologous cellulases can be used to produce ethanol from cellulose. In addition, multiple host cells expressing different heterologous cellulases can be co-cultured together and used to produce ethanol from cellulose. Furthermore, the invention demonstrates for the first time the ability of Kluyveromyces to produce ethanol from cellulose. The yeast strains and co-cultures of yeast strains of the invention can be used to produce ethanol on their own, or can also be used in combination with externally added cellulases to increase the efficiency of saccharification and fermentation processes.
    Type: Application
    Filed: December 22, 2020
    Publication date: December 16, 2021
    Inventors: John McBride, Elena Brevnova, Mark Mellon, Allan Froehlich, Kristen Deleault, Vineet Rajgarhia, Riaan Den Haan, Merja Penttila, Marja Ilmen, Matti Siika-Aho, Jaana Uusitalo, Emily A. Stonehouse, Alan Gilbert, Haowen Xu, Deidre Willies, John Bardsley, Anu Koivula, Sanni Voutilainen
  • Patent number: 11173407
    Abstract: An inflatable water slide, an entertainment device, and a pool are provided. The water slide comprises a slide body that includes a first inflatable chamber having an inclined top surface. The water slide also includes a water spray device located on top of and extending along the inclined top surface of the slide body, and the water spray device is adapted to spray water onto the inclined top surface of the slide body. The entertainment device includes the inflatable water slide and an elongated slide sheet connected to the inflatable water slide. A pool may include the water slide of the present disclosure. The inflatable water slide, entertainment device, and pool of the present disclosure enable water to be sprayed onto the slide body more effectively than in conventional designs, thus preventing situations where water cannot be sprayed onto the slide body.
    Type: Grant
    Filed: April 10, 2020
    Date of Patent: November 16, 2021
    Assignee: BESTWAY INFLATABLES & MATERIAL CORP.
    Inventors: Shuiyong Huang, Patrizio Fumagalli, Matthew Vartola, John McBride, Jiliang Liu, Yuliang Jin, Lei Zhang
  • Patent number: 11168315
    Abstract: The present invention provides for heterologous expression of beta-glucosidase (BGL) polypeptides encoded by Humicola grisea, Candida wickerhamii, Aspergillus aculeatus, Aspergillus oryzae, Penicillium decumbens, Chaetomium globosum, Neocallimastix frontalis, Debaryomyces hansenii, Kluyveromyces marxianus, or Phytophthora infestans in host cells, such as the yeast Saccharomyces cerevisiae. The expression in such host cells of the corresponding genes, and variants and combinations thereof, result in improved specific activity of the expressed BGL. Thus, such genes and expression systems are useful for efficient and cost-effective consolidated bioprocessing systems.
    Type: Grant
    Filed: February 13, 2020
    Date of Patent: November 9, 2021
    Assignee: Lallemand Hungary Liquidity Management LLC
    Inventors: John McBride, Erin Wiswall
  • Patent number: 11063935
    Abstract: Systems and methods for obtaining access to a session with a remote cloud service server. The methods comprising: receiving, by a first client computing device, a user unique identifier from a mobile device located in proximity to the first client computing device; and performing facial recognition operations by the first client computing device subsequent to the reception of the user unique identifier. The facial recognition operations comprise: capturing an image of the mobile device's user; and analyzing the image to obtain a user name associated with the facial features represented therein. A determination is made as to whether the user name matches the user unique identifier. If so, a first session with the remote cloud service server is automatically launched.
    Type: Grant
    Filed: April 23, 2018
    Date of Patent: July 13, 2021
    Assignee: Citrix Systems, Inc.
    Inventors: Rachelle Tobkes, Yufeng Shi, Jyoti Mathur, Christopher Fleck, John McBride, Jacob J. Summers
  • Publication number: 20200353371
    Abstract: An inflatable water slide, an entertainment device, and a pool are provided. The water slide comprises a slide body that includes a first inflatable chamber having an inclined top surface. The water slide also includes a water spray device located on top of and extending along the inclined top surface of the slide body, and the water spray device is adapted to spray water onto the inclined top surface of the slide body. The entertainment device includes the inflatable water slide and an elongated slide sheet connected to the inflatable water slide. A pool may include the water slide of the present disclosure. The inflatable water slide, entertainment device, and pool of the present disclosure enable water to be sprayed onto the slide body more effectively than in conventional designs, thus preventing situations where water cannot be sprayed onto the slide body.
    Type: Application
    Filed: April 10, 2020
    Publication date: November 12, 2020
    Inventors: Shuiyong HUANG, Patrizio FUMAGALLI, Matthew VARTOLA, John MCBRIDE, Jiliang LIU, Yuliang JIN, Lei ZHANG
  • Publication number: 20200248221
    Abstract: The present invention provides for heterologous expression of beta-glucosidase (BGL) polypeptides encoded by Humicola grisea, Candida wickerhamii, Aspergillus aculeatus, Aspergillus oryzae, Penicillium decumbens, Chaetomium globosum, Neocallimastix frontalis, Debaryomyces hansenii, Kluyveromyces marxianus, or Phytophthora infestans in host cells, such as the yeast Saccharomyces cerevisiae. The expression in such host cells of the corresponding genes, and variants and combinations thereof, result in improved specific activity of the expressed BGL. Thus, such genes and expression systems are useful for efficient and cost-effective consolidated bioprocessing systems.
    Type: Application
    Filed: February 13, 2020
    Publication date: August 6, 2020
    Inventors: John McBride, Erin Wiswall
  • Patent number: 10612061
    Abstract: The present invention provides for heterologous expression of beta-glucosidase (BGL) polypeptides encoded by Humicola grisea, Candida wickerhamii, Aspergillus aculeatus, Aspergillus oryzae, Penicillium decumbens, Chaetomium globosum, Neocallimastix frontalis, Debaryomyces hansenii, Kluyveromyces marxianus, or Phytophthora infestans in host cells, such as the yeast Saccharomyces cerevisiae. The expression in such host cells of the corresponding genes, and variants and combinations thereof, result in improved specific activity of the expressed BGL. Thus, such genes and expression systems are useful for efficient and cost-effective consolidated bioprocessing systems.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: April 7, 2020
    Assignee: Lallemand Hungary Liquidity Management LLC
    Inventors: John McBride, Erin Wiswall
  • Patent number: 10428322
    Abstract: The present invention provides for heterologous expression of termite and termite-associated symbiont cellulases. The cellulases can, for example, be codon-optimized and expressed in yeast host cells, such as the yeast Saccharomyces cerevisiae. The cellulases can also be co-expressed in host cells with other cellulases. The expression in such host cells of the termite and termite-associated symbiont cellulases, and variants and combinations thereof, result in yeast with improved cellulosic activity. Thus, such genes and expression systems are useful for efficient and cost-effective consolidated bioprocessing systems.
    Type: Grant
    Filed: January 10, 2019
    Date of Patent: October 1, 2019
    Assignee: Lallemand Hungary Liquidity Management LLC
    Inventors: Elena E. Brevnova, Vineet Rajgarhia, Mark Mellon, Anne Warner, John McBride, Chhayal Gandhi, Erin Wiswall
  • Publication number: 20190127714
    Abstract: The present invention provides for heterologous expression of termite and termite-associated symbiont cellulases. The cellulases can, for example, be codon-optimized and expressed in yeast host cells, such as the yeast Saccharomyces cerevisiae. The cellulases can also be co-expressed in host cells with other cellulases. The expression in such host cells of the termite and termite-associated symbiont cellulases, and variants and combinations thereof, result in yeast with improved cellulosic activity. Thus, such genes and expression systems are useful for efficient and cost-effective consolidated bioprocessing systems.
    Type: Application
    Filed: January 10, 2019
    Publication date: May 2, 2019
    Inventors: Elena E. Brevnova, Vineet Rajgarhia, Mark Mellon, Anne Warner, John McBride, Chhayal Gandhi, Erin Wiswall
  • Patent number: 10214733
    Abstract: The present invention provides for heterologous expression of termite and termite-associated symbiont cellulases. The cellulases can, for example, be codon-optimized and expressed in yeast host cells, such as the yeast Saccharomyces cerevisiae. The cellulases can also be co-expressed in host cells with other cellulases. The expression in such host cells of the termite and termite-associated symbiont cellulases, and variants and combinations thereof, result in yeast with improved cellulosic activity. Thus, such genes and expression systems are useful for efficient and cost-effective consolidated bioprocessing systems.
    Type: Grant
    Filed: November 28, 2017
    Date of Patent: February 26, 2019
    Assignee: Lallemand Hungary Liquidity Management LLC
    Inventors: Elena E. Brevnova, Vineet Rajgarhia, Mark Mellon, Anne Warner, John McBride, Chhayal Gandhi, Erin Wiswall
  • Publication number: 20180258449
    Abstract: The present invention is directed to cellulytic host cells. The host cells of the invention expressing heterologous cellulases and are able to produce ethanol from cellulose. According to the invention, host cells expressing a combination of heterologous cellulases can be used to produce ethanol from cellulose. In addition, multiple host cells expressing different heterologous cellulases can be co-cultured together and used to produce ethanol from cellulose. Furthermore, the invention demonstrates for the first time the ability of Kluyveromyces to produce ethanol from cellulose. The yeast strains and co-cultures of yeast strains of the invention can be used to produce ethanol on their own, or can also be used in combination with externally added cellulases to increase the efficiency of saccharification and fermentation processes.
    Type: Application
    Filed: May 21, 2018
    Publication date: September 13, 2018
    Inventors: John McBride, Elena Brevnova, Mark Mellon, Allan Froehlich, Kristen Deleault, Vineet Rajgarhia, Riaan Den Haan, Merja Penttila, Marja Ilmen, Matti Siika-Aho, Jaana Uusitalo, Emily A. Stonehouse, Alan Gilbert, Haowen Xu, Deidre Willies, John Bardsley, Anu Koivula, Sanni Voutilainen
  • Patent number: 9994835
    Abstract: The present invention is directed to the construction of prototrophic, cellulo lytic strains of Saccharomyces cerevisiae with tethered and secreted cellulases and selection-based improvement of growth on cellulose by these strains. In some embodiments, host cells of the invention are able to produce ethanol using crystalline cellulose as a sole carbon source.
    Type: Grant
    Filed: May 11, 2009
    Date of Patent: June 12, 2018
    Assignee: Lallemand Hungary Liquidity Management LLC
    Inventors: John McBride, Lee Lynd, Kristen Deleault
  • Publication number: 20180155700
    Abstract: The present invention provides for heterologous expression of termite and termite-associated symbiont cellulases. The cellulases can, for example, be codon-optimized and expressed in yeast host cells, such as the yeast Saccharomyces cerevisiae. The cellulases can also be co-expressed in host cells with other cellulases. The expression in such host cells of the termite and termite-associated symbiont cellulases, and variants and combinations thereof, result in yeast with improved cellulosic activity. Thus, such genes and expression systems are useful for efficient and cost-effective consolidated bioprocessing systems.
    Type: Application
    Filed: November 28, 2017
    Publication date: June 7, 2018
    Inventors: Elena E. Brevnova, Vineet Rajgarhia, Mark Mellon, Anne Warner, John McBride, Chhayal Gandhi, Erin Wiswall