Abstract: Disclosed is an annular ear cushion for an earphone configured to be worn at an ear of a user. The ear cushion is configured to abut the head of the user along an annular contact surface of the ear cushion and to abut or face a housing of the earphone along an annular attachment surface of the ear cushion when the user is wearing the earphone in its intended position, thereby reducing the level of sound entering the ear canal of the user from the environment. The ear cushion further comprising an annular exterior surface and an annular interior surface each extending from the contact surface to the attachment surface and facing respectively the environment and the ear canal of the user when the user is wearing the earphone in its intended position. The ear cushion further comprising a foam core (150) having a first acoustic impedance, and a cover having a first portion extending across the exterior surface and a second portion extending across the contact surface.

Abstract: Compounds useful as fluorescent or colored dyes are disclosed. The compounds have the following structure (I): (I) or a stereoisomer, tautomer or salt thereof, wherein R1, R2, R3, R4, R5, L1a, L1b, L2, L3, L4, L5, L6, L7, M1, M2, q, w, m and n are as defined herein. Methods associated with preparation and use of such compounds are also provided.

Abstract: An active noise-reduction headphone arrangement has a housing bearing a loudspeaker having a first diaphragm surface coupled to a first volume of air bounded by and coupled to a user's ear, and a second diaphragm surface bounding a cavity within the housing assembly so as to define a second volume of air, rearward of the diaphragm; a conduit provided in the housing, the conduit being in fluid communication the ambient air via a first acoustic couple means having a first characteristic acoustic impedance, the conduit also being in fluid communication with said second volume of air via a second acoustic couple means having a second characteristic acoustic impedance; and a microphone having an inlet coupled acoustically to a predetermined location within the conduit.

Abstract: A MEMS microphone assembly has an enclosure enclosing a volume of air. A MEMS microphone chip is provided within the enclosure. First and second acoustic ports are formed in the enclosure, defining first and second fluid paths between the volume of air and air outside the enclosure. The MEMS microphone responds to a pre-determined linear interpolative value between two independent pressure signals supplied via first and second ports according to the potentiometic ratio of the acoustic impedances of the first and second ports.

Abstract: An active noise-reduction headphone arrangement has a housing bearing a loudspeaker having a first diaphragm surface coupled to a first volume of air bounded by and coupled to a user's ear, and a second diaphragm surface bounding a cavity within the housing assembly so as to define a second volume of air, rearward of the diaphragm; a conduit provided in the housing, the conduit being in fluid communication the ambient air via a first acoustic couple means having a first characteristic acoustic impedance, the conduit also being in fluid communication with said second volume of air via a second acoustic couple means having a second characteristic acoustic impedance; and a microphone having an inlet coupled acoustically to a predetermined location within the conduit.

Abstract: A MEMS microphone assembly has an enclosure enclosing a volume of air. A MEMS microphone chip is provided within the enclosure. First and second acoustic ports are formed in the enclosure, defining first and second fluid paths between the volume of air and air outside the enclosure. The MEMS microphone responds to a pre-determined linear interpolative value between two independent pressure signals supplied via first and second ports according to the potentiometic ratio of the acoustic impedances of the first and second ports.

Abstract: A portable laminator designed primarily for home use where the laminator includes a handle for carrying which may also act as a guide for articles being fed into the laminator. In alternate embodiments, the laminator includes a cover which may first position acts as a guide for material being fed into the laminator and in a second position acts as a cover for the laminators feed slot. In additional embodiments, the laminator includes a double walled housing to provide insulation from the heating elements.

Abstract: A method and system for increasing the flow resistance of collateral pathways in the lung by employing aspiration to establish an artificial convective flow current between compartments in the lung in order to entrain and deliver a clogging agent preferentially to the collateral pathways. The method may sometimes be performed after lung has been assessed for the presence of collateral pathways.

Abstract: Disclosed is a method of regulating fluid flow for a targeted lung region. The method comprises injecting a therapeutic agent into the targeted lung region. The therapeutic agent induces a reaction in lung tissue of the targeted lung region or in a collateral pathway to the lung region to reduce collateral fluid flow into the targeted lung region. In one aspect, the method additionally comprises deploying a bronchial isolation device in the direct pathway to regulate fluid flow to the targeted lung region through the direct pathway. The therapeutic agent can comprise, for example, a sclerosing agent that induces a reaction that causes sclerosis in the lung tissue.

Abstract: A method and system for increasing the flow resistance of collateral pathways in the lung by employing aspiration to establish an artificial convective flow current between compartments in the lung in order to entrain and deliver a clogging agent preferentially to the collateral pathways. The method may sometimes be performed after lung has been assessed for the presence of collateral pathways.

Abstract: Disclosed is an apparatus for deploying a bronchial isolation device in a bronchial passageway in a lung of a patient. In one embodiment, the apparatus includes an outer shaft having a distal end. A housing is coupled to the distal end of the outer shaft and configured to receive the bronchial device. An inner shaft is slidably disposed within the outer shaft. A handle is adapted to move the outer shaft relative to both the inner shaft and the handle while the inner shaft remains fixed relative to the handle so as to eject the bronchial isolation device from the housing.

Abstract: Disclosed are various disease indications and treatment methods that benefit from selective lung region isolation. A lung region is bronchially isolated by regulating the flow of fluid to and from the lung region, such as by implanting one or more bronchial isolation devices into one or more bronchial passageways that feed air to the lung region. The bronchial isolation devices can comprise, for example, one-way valves, two-way valves, occluders or blockers, ligating clips, glues, sealants, and sclerosing agents.

Abstract: A portable laminator designed primarily for home use where the laminator includes a handle for carrying which may also act as a guide for articles being fed into the laminator. In alternate embodiments, the laminator includes a cover which may first position acts as a guide for material being fed into the laminator and in a second position acts as a cover for the laminators feed slot. In additional embodiments, the laminator includes a double walled housing to provide insulation from the heating elements.

Abstract: A method of treating a lung comprises deploying a delivery catheter through a bronchial tree into a targeted lung region and delivering a fibrinogen suspension through the delivery catheter so that the fibrinogen suspension exits the distal end of the delivery catheter into the targeted lung region. Thrombin is also delivered through the delivery catheter so that the thrombin exits the distal end of the delivery catheter into the targeted lung region. The lung is promoted to collapse.

Abstract: Disclosed are methods and devices for regulating fluid flow in one or more lung regions that are supplied fluid through one or more collateral pathways. An identified region of the lung is targeted for volume reduction or collapse. The targeted lung region is then bronchially isolated to inhibit air from flowing into the targeted lung region through bronchial pathways that directly feed air to the targeted lung region. If the targeted lung region does not collapse after bronchially isolating the targeted lung region, then it is possible that a collateral pathway is feeding air to the targeted lung region, thereby preventing the targeted lung region from collapsing. In such a case, the collateral pathway is identified and air flow into the targeted lung region via the collateral pathway is reduced or eliminated.

Abstract: A portable laminator designed primarily for home use where the laminator includes a handle for carrying which may also act as a guide for articles being fed into the laminator. In alternate embodiments, the laminator includes a cover which may first position acts as a guide for material being fed into the laminator and in a second position acts as a cover for the laminators feed slot. In additional embodiments, the laminator includes a double walled housing to provide insulation from the heating elements.

Abstract: Methods and devices are adapted for regulating fluid flow to and from a region of a patient's lung, such as to achieve a desired fluid flow dynamic to a lung region during respiration and/or to induce collapse in one or more lung regions. Pursuant to an exemplary procedure, an identified region of the lung is targeted for treatment. The targeted lung region is then bronchially isolated to regulate airflow into and/or out of the targeted lung region through one or more bronchial passageways that feed air to the targeted lung region.

Abstract: A method of diagnosing collateral ventilation between regions of a lung includes the step of measuring at least one parameter associated with a target lung region while a catheter is positioned in the target lung region. A level of collateral fluid flow into the target lung region is detected based on the at least one parameter.

Abstract: Delivery system including endoscopes are described. In an embodiment, a delivery system includes a flexible, elongate endoscope extending along a longitudinal axis when the endoscope is straightened and a first lens located on the distal region. The first lens faces a direction transverse to the longitudinal axis. The first lens permits the endoscope to provide an image of anatomical structures that offset from the axis of the endoscope.

Abstract: Disclosed are methods and devices for treating a patient's lung region. A catheter is deployed into the lung. The catheter is used to apply heat to a targeted lung region wherein the heat affects fluid flow within the targeted lung region.