Patents by Inventor John McElver

John McElver has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20140377835
    Abstract: The present invention relates compositions and methods for identifying, isolating, and characterizing herbicide tolerant mutations in monocot plastidic acetyl-CoA carboxylases using a model system.
    Type: Application
    Filed: November 13, 2012
    Publication date: December 25, 2014
    Applicant: BASF SE
    Inventors: Leon Neuteboom, Sherry R. Whitt, John A. McElver, Jill M. Stevenson-Paulik, S. Luke Mankin
  • Publication number: 20120060243
    Abstract: The invention provides transgenic or non-transgenic plants with improved levels of tolerance to AHAS-inhibiting herbicides. The invention also provides nucleic acids encoding mutants of the acetohydroxyacid synthase (AHAS) large subunit, expression vectors, plants comprising the nucleic acids encoding the AHASL subunits containing one, two, or more mutations, plants comprising such AHASL subunit mutant nucleic acids, methods for making and using the same, and methods of controlling weeds.
    Type: Application
    Filed: September 24, 2009
    Publication date: March 8, 2012
    Inventors: Peter Beetham, Dale Carlson, Greg Gocal, John McElver, James Pearce, Christian Schopke, Bijay Singh, Keith Walker
  • Publication number: 20110167522
    Abstract: The invention provides isolated polynucleotides, specifically Cyclin D polynucleotides, and their encoded proteins that are involved in cell cycle regulation. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions. The present invention provides methods and compositions relating to altering cell cycle protein content and/or composition of plants for the purpose of increasing transformation efficiency.
    Type: Application
    Filed: July 28, 2010
    Publication date: July 7, 2011
    Applicant: Pioneer Hi-Bred International, Inc.
    Inventors: Keith S. Lowe, Yumin Tao, William J. Gordon-Kamm, Carolyn A. Gregory, John A. McElver, George J. Hoerster, Sheila E. Maddock
  • Publication number: 20100287641
    Abstract: The invention provides nucleic acids encoding mutants of the acetohydroxyacid synthase (AHAS) large subunit comprising at least two mutations, for example double and triple mutants, which are useful for producing transgenic or non-transgenic plants with improved levels of tolerance to AHAS-inhibiting herbicides. The invention also provides expression vectors, cells, plants comprising the polynucleotides encoding the AHAS large subunit double and triple mutants, plants comprising two or more AHAS large subunit single mutant polypeptides, and methods for making and using the same.
    Type: Application
    Filed: April 3, 2008
    Publication date: November 11, 2010
    Applicant: BASF Plant Science GmbH
    Inventors: John A. McElver, Bijay Singh
  • Publication number: 20100285591
    Abstract: The invention provides isolated polynucleotides, specifically Cyclin D polynucleotides, and their encoded proteins that are involved in cell cycle regulation. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions. The present invention provides methods and compositions relating to altering cell cycle protein content and/or composition of plants for the purpose of increasing transformation efficiency.
    Type: Application
    Filed: July 27, 2010
    Publication date: November 11, 2010
    Applicant: Pioneer Hi-Bred International, Inc.
    Inventors: Keith S. Lowe, Yumin Tao, William J. Gordon-Kamm, Carolyn A. Gregory, John A. McElver, George J. Hoerster, Sheila E. Maddock
  • Patent number: 7799566
    Abstract: The invention provides isolated polynucleotides, specifically Cyclin D polynucleotides, and their encoded proteins that are involved in cell cycle regulation. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions. The present invention provides methods and compositions relating to altering cell cycle protein content and/or composition of plants for the purpose of increasing transformation efficiency.
    Type: Grant
    Filed: November 16, 2006
    Date of Patent: September 21, 2010
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: Keith S. Lowe, Yumin Tao, William J. Gordon-Kamm, Carolyn A. Gregory, John A. McElver, George J. Hoerster, Sheila E. Maddock
  • Publication number: 20080242624
    Abstract: The invention provides isolated polynucleotides, specifically Cyclin D polynucleotides, and their encoded proteins that are involved in cell cycle regulation. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions. The present invention provides methods and compositions relating to altering cell cycle protein content and/or composition of plants for the purpose of increasing transformation efficiency.
    Type: Application
    Filed: November 16, 2006
    Publication date: October 2, 2008
    Applicant: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: Keith S. Lowe, Yumin Tao, William J. Gordon-Kamm, Carolyn A. Gregory, John A. McElver, George J. Hoerster, Sheila E. Maddock
  • Patent number: 6905857
    Abstract: Nucleic acid sequences encoding two RAD51 recombinases active in maize plants are provided. cDNA sequences including the ZmRAD51 coding sequences and unique 3?-untranslated regions which are useful as RFLP probes, are also provided. The production of plasmids containing a nucleic acid sequence encoding a ZmRAD51 fusion protein, as well as the use of the plasmids to introduce the ZmRAD51 coding sequence into a host cell, such as maize cell, are also disclosed.
    Type: Grant
    Filed: September 18, 2002
    Date of Patent: June 14, 2005
    Assignees: Pioneer Hi-Bred International, Inc., Trustees of Columbia University in the City of New York
    Inventors: Benjamin A. Bowen, Mark A. Chamberlin, Bruce J. Drummond, John A. McElver, Rodney J. Rothstein
  • Patent number: 6881539
    Abstract: A method for the rapid isolation and identification of the DNA sequence of transposable element-tagged genes is provided. The method comprises a modified AFLP approach using a transposable element-anchored amplification to identify and clone an amplification product that is associated with a mutant phenotype. Once cloned, the amplification product of interest may be used to screen a cDNA library directly or may be sequenced and compared to available databases for sequence homology. A modification of this approach provides a method for the identification of the location of an additional type of insertion event into genomic DNA, more specifically transgene insertion into the genome of a host organism.
    Type: Grant
    Filed: February 16, 1999
    Date of Patent: April 19, 2005
    Assignee: Pioneer Hi-Bred International Inc.
    Inventors: John A. Arbuckle, Timothy W. Fox, Robert B. Meeley, Benjamin A. Bowen, John A. McElver
  • Publication number: 20040191850
    Abstract: Nucleotide sequences are isolated from Arabidopsis thaliana that code for proteins essential for plant growth and development. The essentially of the proteins may be exploited by recombinantly expressing the proteins and using them in screening assays to identify compounds that interact with or inhibit the proteins and are therefore potential herbicides.
    Type: Application
    Filed: October 29, 2003
    Publication date: September 30, 2004
    Applicant: Syngenta Participations AG
    Inventors: Joshua Zvi Levin, John Tossberg, Qing Zhou, George Aux, John McElver, Carla Thomas, David Andrew Patton, Catherine Frye, Gregory Budziszewski
  • Publication number: 20030213016
    Abstract: The invention provides isolated polynucleotides and their encoded proteins that are involved in cell cycle regulation. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions. The present invention provides methods and compositions relating to altering cell cycle protein content and/or composition of plants.
    Type: Application
    Filed: January 21, 2003
    Publication date: November 13, 2003
    Applicant: Pioneer Hi-Bred International, Inc.
    Inventors: Keith S. Lowe, Yumin Tao, William J. Gordon-Kamm, Carolyn A. Gregory, John A. McElver, George J. Hoerster, Sheila E. Maddock
  • Publication number: 20030110529
    Abstract: The invention provides isolated polynucleotides and their encoded proteins that are involved in cell cycle regulation. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions. The present invention provides methods and compositions relating to altering cell cycle protein content and/or composition of plants.
    Type: Application
    Filed: December 16, 2002
    Publication date: June 12, 2003
    Applicant: Pioneer Hi-Bred International, Inc.
    Inventors: Keith S. Lowe, Yumin Tao, William J. Gordon-Kamm, Carolyn A. Gregory, George J. Hoerster, John A. McElver
  • Publication number: 20030097680
    Abstract: Nucleic acid sequences encoding two RAD51 recombinases active in maize plants are provided. cDNA sequences including the ZmRAD51 coding sequences and unique 3′-untranslated regions which are useful as RFLP probes, are also provided. The production of plasmids containing a nucleic acid sequence encoding a ZmRAD51 fusion protein, as well as the use of the plasmids to introduce the ZmRAD51 coding sequence into a host cell, such as maize cell, are also disclosed.
    Type: Application
    Filed: September 18, 2002
    Publication date: May 22, 2003
    Applicant: Pioneer Hi-Bred International, Inc.
    Inventors: Benjamin A. Bowen, Mark A. Chamberlin, Bruce J. Drummond, John A. McElver, Rodney J. Rothstein
  • Patent number: 6541684
    Abstract: Nucleic acid sequences encoding two RAD51 recombinases active in maize plants are provided. cDNA sequences including the ZmRAD51 coding sequences and unique 3′-untranslated regions which are useful as RFLP probes, are also provided. The production of plasmids containing a nucleic acid sequence encoding a ZmRAD51 fusion protein, as well as the use of the plasmids to introduce the ZmRAD51 coding sequence into a host cell, such as maize cell, are also disclosed.
    Type: Grant
    Filed: February 9, 1999
    Date of Patent: April 1, 2003
    Assignees: Trustees of Columbia University in the City of New York, Pioneer Hi-Bred International, Inc.
    Inventors: Benjamin A. Bowen, Mark A. Chamberlin, Bruce J. Drummond, John A. McElver, Rodney J. Rothstein
  • Patent number: 6518487
    Abstract: The invention provides isolated polynucleotides and their encoded proteins that are involved in cell cycle regulation. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions. The present invention provides methods and compositions relating to altering cell cycle protein content and/or composition of plants.
    Type: Grant
    Filed: September 20, 1999
    Date of Patent: February 11, 2003
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: Keith S. Lowe, Yumin Tao, William J. Gordon-Kamm, Carolyn A. Gregory, George J. Hoerster, John A. McElver
  • Patent number: 6465638
    Abstract: The present invention relates to nucleic acid primers and probes specific for organisms of the Mycobacterium avium complex (MAC) and to their use in nucleic acid amplification methods for the detection and differentiation of such organisms in biological samples. The invention also relates to diagnostic kits for detecting and differentiating the various organisms comprising the MAC.
    Type: Grant
    Filed: June 23, 1998
    Date of Patent: October 15, 2002
    Assignee: Ortho-Clinical Diagnostics, Inc.
    Inventors: Kevin M. Gorman, John A. McElver, Charles P. Cartwright, David R. Patterson
  • Publication number: 20020127537
    Abstract: The invention relates to genes isolated from Arabidopsis that code for proteins essential for normal plant development. The invention also includes the methods of using these proteins to discover new herbicides, based on the essentiality of the genes for normal growth and development. The invention can also be used in a screening assay to identify inhibitors that are potential herbicides. The invention is also applied to the development of herbicide tolerant plants, plant tissues, plant seeds, and plant cells.
    Type: Application
    Filed: June 28, 2001
    Publication date: September 12, 2002
    Inventors: David A. Patton, Carl S. Ashby, Sandra L. Volrath, John A. McElver, Michael W. Bauer
  • Patent number: 6388169
    Abstract: The present invention provides methods and compositions relating to altering RecA content and/or composition of plants. The invention provides isolated nucleic acids and their encoded proteins that are homologous to bacterial RecA genes. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions. The plant recA polynucleotides and their cognate products are useful for gene targeting in maize and other plant species and for use as a molecular marker.
    Type: Grant
    Filed: May 12, 1999
    Date of Patent: May 14, 2002
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: Pramod B. Mahajan, Jinrui Shi, Christopher Baszczynski, John McElver, Benjamin Bowen
  • Patent number: 6300091
    Abstract: The invention relates to genes isolated from Arabidopsis that code for proteins essential for normal plant development. The invention also includes the methods of using these proteins to discover new herbicides, based on the essentiality of the genes for normal growth and development. The invention can also be used in a screening assay to identify inhibitors that are potential herbicides. The invention is also applied to the development of herbicide tolerant plants, plant tissues, plant seeds, and plant cells.
    Type: Grant
    Filed: February 14, 2000
    Date of Patent: October 9, 2001
    Assignee: Syngenta Participations AG
    Inventors: David A. Patton, Carl S. Ashby, John A. McElver
  • Publication number: 20010019822
    Abstract: The present invention relates to nucleic acid primers and probes specific for organisms of the Mycobacterium avium complex (MAC) and to their use in nucleic acid amplification methods for the detection and differentiation of such organisms in biological samples. The invention also relates to diagnostic kits for detecting and differentiating the various organisms comprising the MAC.
    Type: Application
    Filed: June 23, 1998
    Publication date: September 6, 2001
    Inventors: KEVIN M. GORMAN, JOHN A. MCELVER, CHARLES P. CARTWRIGHT, DAVID R. PATTERSON