Patents by Inventor John McElver
John McElver has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20140377835Abstract: The present invention relates compositions and methods for identifying, isolating, and characterizing herbicide tolerant mutations in monocot plastidic acetyl-CoA carboxylases using a model system.Type: ApplicationFiled: November 13, 2012Publication date: December 25, 2014Applicant: BASF SEInventors: Leon Neuteboom, Sherry R. Whitt, John A. McElver, Jill M. Stevenson-Paulik, S. Luke Mankin
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Publication number: 20120060243Abstract: The invention provides transgenic or non-transgenic plants with improved levels of tolerance to AHAS-inhibiting herbicides. The invention also provides nucleic acids encoding mutants of the acetohydroxyacid synthase (AHAS) large subunit, expression vectors, plants comprising the nucleic acids encoding the AHASL subunits containing one, two, or more mutations, plants comprising such AHASL subunit mutant nucleic acids, methods for making and using the same, and methods of controlling weeds.Type: ApplicationFiled: September 24, 2009Publication date: March 8, 2012Inventors: Peter Beetham, Dale Carlson, Greg Gocal, John McElver, James Pearce, Christian Schopke, Bijay Singh, Keith Walker
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Publication number: 20110167522Abstract: The invention provides isolated polynucleotides, specifically Cyclin D polynucleotides, and their encoded proteins that are involved in cell cycle regulation. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions. The present invention provides methods and compositions relating to altering cell cycle protein content and/or composition of plants for the purpose of increasing transformation efficiency.Type: ApplicationFiled: July 28, 2010Publication date: July 7, 2011Applicant: Pioneer Hi-Bred International, Inc.Inventors: Keith S. Lowe, Yumin Tao, William J. Gordon-Kamm, Carolyn A. Gregory, John A. McElver, George J. Hoerster, Sheila E. Maddock
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Publication number: 20100287641Abstract: The invention provides nucleic acids encoding mutants of the acetohydroxyacid synthase (AHAS) large subunit comprising at least two mutations, for example double and triple mutants, which are useful for producing transgenic or non-transgenic plants with improved levels of tolerance to AHAS-inhibiting herbicides. The invention also provides expression vectors, cells, plants comprising the polynucleotides encoding the AHAS large subunit double and triple mutants, plants comprising two or more AHAS large subunit single mutant polypeptides, and methods for making and using the same.Type: ApplicationFiled: April 3, 2008Publication date: November 11, 2010Applicant: BASF Plant Science GmbHInventors: John A. McElver, Bijay Singh
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Publication number: 20100285591Abstract: The invention provides isolated polynucleotides, specifically Cyclin D polynucleotides, and their encoded proteins that are involved in cell cycle regulation. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions. The present invention provides methods and compositions relating to altering cell cycle protein content and/or composition of plants for the purpose of increasing transformation efficiency.Type: ApplicationFiled: July 27, 2010Publication date: November 11, 2010Applicant: Pioneer Hi-Bred International, Inc.Inventors: Keith S. Lowe, Yumin Tao, William J. Gordon-Kamm, Carolyn A. Gregory, John A. McElver, George J. Hoerster, Sheila E. Maddock
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Patent number: 7799566Abstract: The invention provides isolated polynucleotides, specifically Cyclin D polynucleotides, and their encoded proteins that are involved in cell cycle regulation. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions. The present invention provides methods and compositions relating to altering cell cycle protein content and/or composition of plants for the purpose of increasing transformation efficiency.Type: GrantFiled: November 16, 2006Date of Patent: September 21, 2010Assignee: Pioneer Hi-Bred International, Inc.Inventors: Keith S. Lowe, Yumin Tao, William J. Gordon-Kamm, Carolyn A. Gregory, John A. McElver, George J. Hoerster, Sheila E. Maddock
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Publication number: 20080242624Abstract: The invention provides isolated polynucleotides, specifically Cyclin D polynucleotides, and their encoded proteins that are involved in cell cycle regulation. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions. The present invention provides methods and compositions relating to altering cell cycle protein content and/or composition of plants for the purpose of increasing transformation efficiency.Type: ApplicationFiled: November 16, 2006Publication date: October 2, 2008Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: Keith S. Lowe, Yumin Tao, William J. Gordon-Kamm, Carolyn A. Gregory, John A. McElver, George J. Hoerster, Sheila E. Maddock
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Patent number: 6905857Abstract: Nucleic acid sequences encoding two RAD51 recombinases active in maize plants are provided. cDNA sequences including the ZmRAD51 coding sequences and unique 3?-untranslated regions which are useful as RFLP probes, are also provided. The production of plasmids containing a nucleic acid sequence encoding a ZmRAD51 fusion protein, as well as the use of the plasmids to introduce the ZmRAD51 coding sequence into a host cell, such as maize cell, are also disclosed.Type: GrantFiled: September 18, 2002Date of Patent: June 14, 2005Assignees: Pioneer Hi-Bred International, Inc., Trustees of Columbia University in the City of New YorkInventors: Benjamin A. Bowen, Mark A. Chamberlin, Bruce J. Drummond, John A. McElver, Rodney J. Rothstein
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Transposable element-anchored, amplification method for isolation and identification of tagged genes
Patent number: 6881539Abstract: A method for the rapid isolation and identification of the DNA sequence of transposable element-tagged genes is provided. The method comprises a modified AFLP approach using a transposable element-anchored amplification to identify and clone an amplification product that is associated with a mutant phenotype. Once cloned, the amplification product of interest may be used to screen a cDNA library directly or may be sequenced and compared to available databases for sequence homology. A modification of this approach provides a method for the identification of the location of an additional type of insertion event into genomic DNA, more specifically transgene insertion into the genome of a host organism.Type: GrantFiled: February 16, 1999Date of Patent: April 19, 2005Assignee: Pioneer Hi-Bred International Inc.Inventors: John A. Arbuckle, Timothy W. Fox, Robert B. Meeley, Benjamin A. Bowen, John A. McElver -
Nucleic acid molecules encoding proteins essential for plant growth and development and uses thereof
Publication number: 20040191850Abstract: Nucleotide sequences are isolated from Arabidopsis thaliana that code for proteins essential for plant growth and development. The essentially of the proteins may be exploited by recombinantly expressing the proteins and using them in screening assays to identify compounds that interact with or inhibit the proteins and are therefore potential herbicides.Type: ApplicationFiled: October 29, 2003Publication date: September 30, 2004Applicant: Syngenta Participations AGInventors: Joshua Zvi Levin, John Tossberg, Qing Zhou, George Aux, John McElver, Carla Thomas, David Andrew Patton, Catherine Frye, Gregory Budziszewski -
Publication number: 20030213016Abstract: The invention provides isolated polynucleotides and their encoded proteins that are involved in cell cycle regulation. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions. The present invention provides methods and compositions relating to altering cell cycle protein content and/or composition of plants.Type: ApplicationFiled: January 21, 2003Publication date: November 13, 2003Applicant: Pioneer Hi-Bred International, Inc.Inventors: Keith S. Lowe, Yumin Tao, William J. Gordon-Kamm, Carolyn A. Gregory, John A. McElver, George J. Hoerster, Sheila E. Maddock
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Publication number: 20030110529Abstract: The invention provides isolated polynucleotides and their encoded proteins that are involved in cell cycle regulation. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions. The present invention provides methods and compositions relating to altering cell cycle protein content and/or composition of plants.Type: ApplicationFiled: December 16, 2002Publication date: June 12, 2003Applicant: Pioneer Hi-Bred International, Inc.Inventors: Keith S. Lowe, Yumin Tao, William J. Gordon-Kamm, Carolyn A. Gregory, George J. Hoerster, John A. McElver
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Publication number: 20030097680Abstract: Nucleic acid sequences encoding two RAD51 recombinases active in maize plants are provided. cDNA sequences including the ZmRAD51 coding sequences and unique 3′-untranslated regions which are useful as RFLP probes, are also provided. The production of plasmids containing a nucleic acid sequence encoding a ZmRAD51 fusion protein, as well as the use of the plasmids to introduce the ZmRAD51 coding sequence into a host cell, such as maize cell, are also disclosed.Type: ApplicationFiled: September 18, 2002Publication date: May 22, 2003Applicant: Pioneer Hi-Bred International, Inc.Inventors: Benjamin A. Bowen, Mark A. Chamberlin, Bruce J. Drummond, John A. McElver, Rodney J. Rothstein
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Patent number: 6541684Abstract: Nucleic acid sequences encoding two RAD51 recombinases active in maize plants are provided. cDNA sequences including the ZmRAD51 coding sequences and unique 3′-untranslated regions which are useful as RFLP probes, are also provided. The production of plasmids containing a nucleic acid sequence encoding a ZmRAD51 fusion protein, as well as the use of the plasmids to introduce the ZmRAD51 coding sequence into a host cell, such as maize cell, are also disclosed.Type: GrantFiled: February 9, 1999Date of Patent: April 1, 2003Assignees: Trustees of Columbia University in the City of New York, Pioneer Hi-Bred International, Inc.Inventors: Benjamin A. Bowen, Mark A. Chamberlin, Bruce J. Drummond, John A. McElver, Rodney J. Rothstein
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Patent number: 6518487Abstract: The invention provides isolated polynucleotides and their encoded proteins that are involved in cell cycle regulation. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions. The present invention provides methods and compositions relating to altering cell cycle protein content and/or composition of plants.Type: GrantFiled: September 20, 1999Date of Patent: February 11, 2003Assignee: Pioneer Hi-Bred International, Inc.Inventors: Keith S. Lowe, Yumin Tao, William J. Gordon-Kamm, Carolyn A. Gregory, George J. Hoerster, John A. McElver
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Patent number: 6465638Abstract: The present invention relates to nucleic acid primers and probes specific for organisms of the Mycobacterium avium complex (MAC) and to their use in nucleic acid amplification methods for the detection and differentiation of such organisms in biological samples. The invention also relates to diagnostic kits for detecting and differentiating the various organisms comprising the MAC.Type: GrantFiled: June 23, 1998Date of Patent: October 15, 2002Assignee: Ortho-Clinical Diagnostics, Inc.Inventors: Kevin M. Gorman, John A. McElver, Charles P. Cartwright, David R. Patterson
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Publication number: 20020127537Abstract: The invention relates to genes isolated from Arabidopsis that code for proteins essential for normal plant development. The invention also includes the methods of using these proteins to discover new herbicides, based on the essentiality of the genes for normal growth and development. The invention can also be used in a screening assay to identify inhibitors that are potential herbicides. The invention is also applied to the development of herbicide tolerant plants, plant tissues, plant seeds, and plant cells.Type: ApplicationFiled: June 28, 2001Publication date: September 12, 2002Inventors: David A. Patton, Carl S. Ashby, Sandra L. Volrath, John A. McElver, Michael W. Bauer
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Patent number: 6388169Abstract: The present invention provides methods and compositions relating to altering RecA content and/or composition of plants. The invention provides isolated nucleic acids and their encoded proteins that are homologous to bacterial RecA genes. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions. The plant recA polynucleotides and their cognate products are useful for gene targeting in maize and other plant species and for use as a molecular marker.Type: GrantFiled: May 12, 1999Date of Patent: May 14, 2002Assignee: Pioneer Hi-Bred International, Inc.Inventors: Pramod B. Mahajan, Jinrui Shi, Christopher Baszczynski, John McElver, Benjamin Bowen
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Patent number: 6300091Abstract: The invention relates to genes isolated from Arabidopsis that code for proteins essential for normal plant development. The invention also includes the methods of using these proteins to discover new herbicides, based on the essentiality of the genes for normal growth and development. The invention can also be used in a screening assay to identify inhibitors that are potential herbicides. The invention is also applied to the development of herbicide tolerant plants, plant tissues, plant seeds, and plant cells.Type: GrantFiled: February 14, 2000Date of Patent: October 9, 2001Assignee: Syngenta Participations AGInventors: David A. Patton, Carl S. Ashby, John A. McElver
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Publication number: 20010019822Abstract: The present invention relates to nucleic acid primers and probes specific for organisms of the Mycobacterium avium complex (MAC) and to their use in nucleic acid amplification methods for the detection and differentiation of such organisms in biological samples. The invention also relates to diagnostic kits for detecting and differentiating the various organisms comprising the MAC.Type: ApplicationFiled: June 23, 1998Publication date: September 6, 2001Inventors: KEVIN M. GORMAN, JOHN A. MCELVER, CHARLES P. CARTWRIGHT, DAVID R. PATTERSON