Abstract: The system and method of pupil size independent pupillometry used for assessing critical diagnostic characteristics relating to neurotransmission and neuroactivity as applied to toxin exposure. The system and method utilizes the timing of a response to stimuli for a pupil of an individual, characterizes the timed responses, determines the latency of the timed responses, measures the minimum constriction value for the timed responses; and assesses the timed responses collected to diagnose changes in neurotransmission and neuroactivity for an individual exposed to organophosphate (OP) nerve agents or botulinum toxin (BTX).

Abstract: The system and method of size independent pupillometry used for assessing critical diagnostic characteristics relating to traumatic brain injury (TBI). The system and method utilizes the timing of a response to a stimuli for one or more pupils of an individual, characterizes the one or more timed responses, determines the latency of the one or more timed responses, measures the minimum constriction value for the one or more timed responses; and assesses the one or more timed responses collected to detect changes in neurotransmission and neuroactivity of an individual to assess the presence of a traumatic brain injury.

Abstract: A system and method for finding the position of a waveguide in a planar optical device that has application to the coupling of light to a planar optical waveguide without connectors. The system comprises input and output optical fiber probes, a light source, a photo or light detector and a optical power meter. The light detector is positioned at the exit of the optical waveguide of interest. Typically, the position of the waveguide will be known with some window of uncertainty. Assuming that the photo detector is a photodiode, the area of the photodiode is preferably large enough that the exit of the waveguide can be assumed to lie within the detection area of the photodiode. The input optical fiber probe is coupled to the light source and is moved across the uncertainty window of the entry to the waveguide. The light transmitted through the waveguide to the photo detector is measured and used to find the position of the entry to the way guide.